Sang Min Lim

Sang Min Lim

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Sang Min Lim

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Decoding Principles of Selective GPCR-Gα Coupling.

Authors:
Sang Min Lim

Biochemistry 2019 Sep 26. Epub 2019 Sep 26.

Convergence Research Center for Diagnosis, Treatment and Care System of Dementia , Korea Institute of Science and Technology , Seoul 02792 , Republic of Korea.

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http://dx.doi.org/10.1021/acs.biochem.9b00828DOI Listing
September 2019

Structural hybridization of pyrrolidine-based T-type calcium channel inhibitors and exploration of their analgesic effects in a neuropathic pain model.

Bioorg Med Chem Lett 2019 May 21;29(10):1168-1172. Epub 2019 Mar 21.

Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology, 5, Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, 5, Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2019.03.026DOI Listing
May 2019

Synthesis and biological evaluation of pyrrolidine-based T-type calcium channel inhibitors for the treatment of neuropathic pain.

J Enzyme Inhib Med Chem 2018 Dec;33(1):1460-1471

a Convergence Research Center for Diagnosis, Treatment and Care System of Dementia , Korea Institute of Science and Technology , Seoul , Republic of Korea.

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http://dx.doi.org/10.1080/14756366.2018.1513926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151954PMC
December 2018

Identification of crizotinib derivatives as potent SHIP2 inhibitors for the treatment of Alzheimer's disease.

Eur J Med Chem 2018 Sep 3;157:405-422. Epub 2018 Aug 3.

Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea; KHU-KIST Department of Converging Science and Technology, Kyung Hee University, Seoul, 02447, Republic of Korea; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul, 02792, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.07.071DOI Listing
September 2018

GRP78-targeted in-silico virtual screening of novel anticancer agents.

Chem Biol Drug Des 2018 08 31;92(2):1555-1566. Epub 2018 May 31.

Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology, Seoul, Korea.

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http://doi.wiley.com/10.1111/cbdd.13322
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http://dx.doi.org/10.1111/cbdd.13322DOI Listing
August 2018

Enzyme/whole-cell biotransformation of plant oils, yeast derived oils, and microalgae fatty acid methyl esters into n-nonanoic acid, 9-hydroxynonanoic acid, and 1,9-nonanedioic acid.

Bioresour Technol 2018 Mar 15;251:288-294. Epub 2017 Dec 15.

Department of Food Science and Engineering, Ewha Womans University, Seoul 03760, Republic of Korea; Institute of Molecular Microbiology and Biosystems Engineering, Ewha Womans University, Seoul 03760, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.biortech.2017.12.036DOI Listing
March 2018

In silico-designed novel non-peptidic ABAD L hot spot mimetics reverse Aβ-induced mitochondrial impairments in vitro.

Chem Biol Drug Des 2017 Dec 27;90(6):1041-1055. Epub 2017 Jul 27.

Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology, Seoul, Korea.

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http://dx.doi.org/10.1111/cbdd.13065DOI Listing
December 2017

Discovery of thienopyrrolotriazine derivatives to protect mitochondrial function against Aβ-induced neurotoxicity.

Eur J Med Chem 2017 Dec 21;141:240-256. Epub 2017 Sep 21.

Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul 02792, Republic of Korea; Biological Chemistry, Korea University of Science and Technology, Gajeong-ro 217, Yuseong-gu, Daejon 34113, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2017.09.033DOI Listing
December 2017

Ligand-controlled Regiodivergent C-H Alkenylation of Pyrazoles and its Application to the Synthesis of Indazoles.

Angew Chem Int Ed Engl 2017 12 27;56(51):16262-16266. Epub 2017 Nov 27.

Department of Chemistry and Chemistry Institute of Functional Materials, Pusan National University, Busan, 46241, Republic of Korea.

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http://dx.doi.org/10.1002/anie.201709162DOI Listing
December 2017

Antifungal Effects of Synthetic Human Beta-defensin-3-C15 Peptide on Candida albicans-infected Root Dentin.

J Endod 2017 Nov 23;43(11):1857-1861. Epub 2017 Sep 23.

Department of Conservative Dentistry, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.joen.2017.06.035DOI Listing
November 2017

Discovery of non-peptidic small molecule inhibitors of cyclophilin D as neuroprotective agents in Aβ-induced mitochondrial dysfunction.

J Comput Aided Mol Des 2017 Oct 14;31(10):929-941. Epub 2017 Sep 14.

Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul, 02792, Republic of Korea.

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http://dx.doi.org/10.1007/s10822-017-0067-9DOI Listing
October 2017

Various heat-treated nickel-titanium rotary instruments evaluated in S-shaped simulated resin canals.

J Dent Sci 2017 Mar 2;12(1):14-20. Epub 2016 Jul 2.

Department of Conservative Dentistry, Dental Research Institute, Seoul National University Dental Hospital, Seoul National University School of Dentistry, Seoul, Republic of Korea.

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https://linkinghub.elsevier.com/retrieve/pii/S19917902163002
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http://dx.doi.org/10.1016/j.jds.2016.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395266PMC
March 2017

Small molecule selectively suppresses MYC transcription in cancer cells.

Proc Natl Acad Sci U S A 2017 03 14;114(13):3497-3502. Epub 2017 Mar 14.

California Institute for Biomedical Research, La Jolla, CA 92037

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http://dx.doi.org/10.1073/pnas.1702663114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380033PMC
March 2017

Effect of Different Agitation Techniques on the Penetration of Irrigant and Sealer into Dentinal Tubules.

Photomed Laser Surg 2017 Feb 3;35(2):71-77. Epub 2016 Nov 3.

1 Department of Conservative Dentistry, Dental Research Institute, Seoul National University Dental Hospital, Seoul National University School of Dentistry , Seoul, Republic of Korea.

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http://dx.doi.org/10.1089/pho.2016.4125DOI Listing
February 2017

Covalent Guanosine Mimetic Inhibitors of G12C KRAS.

ACS Med Chem Lett 2017 Jan 30;8(1):61-66. Epub 2016 Nov 30.

Department of Cancer Biology, Dana Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02115, United States; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02215, United States.

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http://pubs.acs.org/doi/10.1021/acsmedchemlett.6b00373
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http://dx.doi.org/10.1021/acsmedchemlett.6b00373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238463PMC
January 2017

Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.

Chem Biol Drug Des 2016 Dec 27;88(6):807-819. Epub 2016 Jul 27.

Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology, Seoul, Korea.

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http://dx.doi.org/10.1111/cbdd.12810DOI Listing
December 2016

Optimization and biological evaluation of aminopyrimidine-based IκB kinase β inhibitors with potent anti-inflammatory effects.

Eur J Med Chem 2016 Nov 1;123:544-556. Epub 2016 Aug 1.

Center for Catalytic Hydrocarbon Functionalizations, Institute of Basic Science (IBS), Daejeon 34141, South Korea; Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2016.07.075DOI Listing
November 2016

Development of a floating photobioreactor with internal partitions for efficient utilization of ocean wave into improved mass transfer and algal culture mixing.

Bioprocess Biosyst Eng 2016 May 8;39(5):713-23. Epub 2016 Feb 8.

National Marine Bioenergy R&D Center & Department of Biological Engineering, Inha University, Incheon, 22212, Korea.

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http://dx.doi.org/10.1007/s00449-016-1552-6DOI Listing
May 2016

Strategies to overcome acquired resistances conferred by mutations in the kinase domain of EGFR.

Future Med Chem 2016 05 19;8(8):853-78. Epub 2016 May 19.

Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS), Daejeon 34141, Korea.

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http://dx.doi.org/10.4155/fmc-2016-0019DOI Listing
May 2016

Antifungal effects of synthetic human β-defensin 3-C15 peptide.

Restor Dent Endod 2016 May 17;41(2):91-7. Epub 2016 Mar 17.

Department of Conservative Dentistry, Seoul National University Dental Hospital, Seoul National University School of Dentistry and Dental Research Institute, Seoul, Korea.

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http://dx.doi.org/10.5395/rde.2016.41.2.91DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868883PMC
May 2016

Evaluation of three obturation techniques in the apical third of mandibular first molar mesial root canals using micro-computed tomography.

J Dent Sci 2016 Mar 6;11(1):95-102. Epub 2016 Jan 6.

Department of Conservative Dentistry, Dental Research Institute, Seoul National University Dental Hospital, Seoul National University School of Dentistry, Seoul, Republic of Korea.

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https://linkinghub.elsevier.com/retrieve/pii/S19917902150013
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http://dx.doi.org/10.1016/j.jds.2015.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395149PMC
March 2016

Effect of acidic solutions on the microhardness of dentin and set OrthoMTA and their cytotoxicity on murine macrophage.

Restor Dent Endod 2016 Feb 1;41(1):12-21. Epub 2015 Dec 1.

Department of Conservative Dentistry, Dental Research Institute, Seoul National University Dental Hospital, Seoul National University School of Dentistry, Seoul, Korea.

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http://dx.doi.org/10.5395/rde.2016.41.1.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751202PMC
February 2016

Discovery of wrightiadione as a novel template for the TrkA kinase inhibitors.

Bioorg Med Chem Lett 2015 Nov 30;25(22):5186-9. Epub 2015 Sep 30.

Center for Catalytic Hydrocarbon Functionalization, Institute for Basic Science (IBS), Daejeon 305-701, Republic of Korea; Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2015.09.070DOI Listing
November 2015

Identification of β-Lapachone Analogs as Novel MALT1 Inhibitors To Treat an Aggressive Subtype of Diffuse Large B-Cell Lymphoma.

J Med Chem 2015 Nov 29;58(21):8491-502. Epub 2015 Oct 29.

Center for Catalytic Hydrocarbon Functionalizations, Institute of Basic Science (IBS) , Daejeon 305-701, Korea.

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http://pubs.acs.org/doi/10.1021/acs.jmedchem.5b01415
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http://dx.doi.org/10.1021/acs.jmedchem.5b01415DOI Listing
November 2015

Development of small molecules targeting the pseudokinase Her3.

Bioorg Med Chem Lett 2015 Aug 11;25(16):3382-9. Epub 2015 May 11.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2015.04.103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633287PMC
August 2015

Bacterial entombment by intratubular mineralization following orthograde mineral trioxide aggregate obturation: a scanning electron microscopy study.

Int J Oral Sci 2014 Dec 11;6(4):227-32. Epub 2014 Jul 11.

Department of Conservative Dentistry, Dental Research Institute, Seoul National University Dental Hospital, Seoul National University School of Dentistry, Seoul, Korea.

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http://dx.doi.org/10.1038/ijos.2014.30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153584PMC
December 2014

Pharmacological targeting of the pseudokinase Her3.

Nat Chem Biol 2014 Dec 19;10(12):1006-12. Epub 2014 Oct 19.

1] Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. [2] Department of Biological Chemistry &Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nchembio.1658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232461PMC
December 2014

Transplantation of insulin-producing cells differentiated from human periosteum-derived progenitor cells ameliorate hyperglycemia in diabetic mice.

Transplantation 2014 Nov;98(10):1040-7

1 College of Pharmacy and Gachon Institute of Pharmaceutical Science, Gachon University, Yeonsu-ku, Incheon, South Korea. 2 Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Yeonsu-ku, Incheon, South Korea. 3 Department of Biological Engineering, Inha University, Incheon, South Korea. 4 Department of Applied Bioscience, CHA University, Seoul, South Korea. 5 Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea. 6 Gachon Medical Research Institute, Gil Hospital, Incheon, South Korea. 7 Address correspondence to: Hee-Sook Jun, Ph.D., College of Pharmacy and Gachon Institute of Pharmaceutical Science, Gachon University, 7-45 Songdo-dong, Yeonsu-ku, Incheon 406-840, South Korea.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/TP.0000000000000388DOI Listing
November 2014

Comparison of alternative image reformatting techniques in micro-computed tomography and tooth clearing for detailed canal morphology.

J Endod 2014 Mar 25;40(3):417-22. Epub 2013 Oct 25.

Department of Conservative Dentistry, Dental Research Institute, Seoul National University Dental Hospital, Seoul National University School of Dentistry, Seoul National University, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.joen.2013.09.014DOI Listing
March 2014

Therapeutic targeting of oncogenic K-Ras by a covalent catalytic site inhibitor.

Angew Chem Int Ed Engl 2014 Jan 20;53(1):199-204. Epub 2013 Nov 20.

Department of Cancer Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215 (USA); Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, 250 Longwood Avenue, Boston, MA 02115 (USA); Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138 (USA).

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http://ccc.chem.pitt.edu/wipf/Current%20Literature/Evan_3.pd
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http://doi.wiley.com/10.1002/anie.201307387
Publisher Site
http://dx.doi.org/10.1002/anie.201307387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914205PMC
January 2014

Antibacterial efficacy of a human β-defensin-3 peptide on multispecies biofilms.

J Endod 2013 Dec 11;39(12):1625-9. Epub 2013 Sep 11.

Department of Conservative Dentistry, Dental Research Institute, Seoul National University Dental Hospital, Seoul National University School of Dentistry, Seoul, Republic of Korea.

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http://dx.doi.org/10.1016/j.joen.2013.07.035DOI Listing
December 2013

Microbial analysis in primary and persistent endodontic infections by using pyrosequencing.

J Endod 2013 Sep;39(9):1136-40

Division of Periodontology, School of Dental Medicine, University of Connecticut Health Center, Farmington, Connecticut, USA.

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http://dx.doi.org/10.1016/j.joen.2013.05.001DOI Listing
September 2013

Glucose-stimulated insulin secretion of various mesenchymal stem cells after insulin-producing cell differentiation.

J Biosci Bioeng 2012 Jun 16;113(6):771-7. Epub 2012 Mar 16.

Department of Biological Engineering, Inha University, Incheon 402-751, Republic of Korea.

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http://dx.doi.org/10.1016/j.jbiosc.2012.02.007DOI Listing
June 2012

Effects of mixed feeder cells on the expansion of CD34⁺ cells.

J Biosci Bioeng 2012 Mar 6;113(3):389-94. Epub 2011 Dec 6.

Department of Applied Bioscience, CHA University, Seoul 135-081, Republic of Korea.

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https://linkinghub.elsevier.com/retrieve/pii/S13891723110045
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http://dx.doi.org/10.1016/j.jbiosc.2011.11.006DOI Listing
March 2012

Optimization of ex vivo hematopoietic stem cell expansion in intermittent dynamic cultures.

Biotechnol Lett 2010 Dec 22;32(12):1969-75. Epub 2010 Jul 22.

Department of Applied Bioscience, CHA University, Seoul, 135-081, Korea.

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http://dx.doi.org/10.1007/s10529-010-0355-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974206PMC
December 2010

Broad spectrum alkynyl inhibitors of T315I Bcr-Abl.

Bioorg Med Chem Lett 2010 Jul 19;20(14):4196-200. Epub 2010 May 19.

Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, United States.

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http://dx.doi.org/10.1016/j.bmcl.2010.05.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901992PMC
July 2010

A comparison of nickel-titanium rotary instruments manufactured using different methods and cross-sectional areas: ability to resist cyclic fatigue.

Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010 Apr;109(4):622-8

Department of Conservative Dentistry, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.

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http://dx.doi.org/10.1016/j.tripleo.2009.12.025DOI Listing
April 2010

Production and characterization of long-acting recombinant human albumin-EPO fusion protein expressed in CHO cell.

Protein Expr Purif 2009 Dec 10;68(2):137-45. Epub 2009 Jul 10.

Boryung Central Research Institute, Boryung Pharmaceutical Co. Ltd., Ansan 425-839, South Korea.

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http://dx.doi.org/10.1016/j.pep.2009.07.003DOI Listing
December 2009

A method for the preparation of differentiated trans-1,2-diol derivatives with enantio- and diastereocontrol.

J Am Chem Soc 2009 Apr;131(16):5763-5

Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

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http://dx.doi.org/10.1021/ja901283qDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681323PMC
April 2009

Immunogenicity and safety of Vi capsular polysaccharide typhoid vaccine in healthy persons in Korea.

J Microbiol Biotechnol 2007 Apr;17(4):611-5

Central Research Institute, Boryung Pharm. Co. Ltd., Ansan 425-120, Korea.

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April 2007

Production and characterization of human CTLA4Ig expressed in transgenic rice cell suspension cultures.

Protein Expr Purif 2007 Feb 16;51(2):293-302. Epub 2006 Sep 16.

Boryung Pharmaceutical Co. Ltd., Ansan 425-120, Republic of Korea.

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http://dx.doi.org/10.1016/j.pep.2006.08.019DOI Listing
February 2007

Chondrogenesis of human periosteum-derived progenitor cells in atelocollagen.

Biotechnol Lett 2007 Feb 22;29(2):323-9. Epub 2006 Nov 22.

Department of Biological Engineering, Inha University, Incheon, 402-751, Korea,

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http://link.springer.com/10.1007/s10529-006-9240-2
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http://dx.doi.org/10.1007/s10529-006-9240-2DOI Listing
February 2007

Characterization of human cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (hCTLA4Ig) expressed in transgenic rice cell suspension cultures.

Biotechnol Lett 2006 Dec 28;28(24):2039-48. Epub 2006 Oct 28.

Boryung Central Research Institute, Boryung Pharmaceutical Co. Ltd., Ansan, Kyungki-do, 425-120, Korea.

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http://dx.doi.org/10.1007/s10529-006-9191-7DOI Listing
December 2006

Total synthesis of IKD-8344.

Angew Chem Int Ed Engl 2006 Oct;45(42):7072-5

Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151-747, Korea.

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http://dx.doi.org/10.1002/anie.200602860DOI Listing
October 2006

Continuous-flow fractionation of animal cells in microfluidic device using aqueous two-phase extraction.

Biomed Microdevices 2005 Sep;7(3):189-95

Department of Biological Engineering, Incheon 402-751, Korea.

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http://dx.doi.org/10.1007/s10544-005-3025-6DOI Listing
September 2005

Isolation of human periosteum-derived progenitor cells using immunophenotypes for chondrogenesis.

Biotechnol Lett 2005 May;27(9):607-11

Department of Biological Engineering, Inha University, Incheon 402-751, Korea.

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http://link.springer.com/10.1007/s10529-005-3625-5
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http://dx.doi.org/10.1007/s10529-005-3625-5DOI Listing
May 2005

Synthesis of the proposed structure of feigrisolide C.

Org Lett 2005 Mar;7(6):1085-7

Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151-747, Korea.

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http://dx.doi.org/10.1021/ol0500160DOI Listing
March 2005

Total synthesis of ambruticin.

Angew Chem Int Ed Engl 2002 Jan;41(1):176-8

School of Chemistry and Molecular Engineering, Seoul National University, Korea.

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http://dx.doi.org/10.1002/1521-3773(20020104)41:1<176::aid-anie176>3.0.co;2-#DOI Listing
January 2002