Publications by authors named "Sang J Chung"

78Publications

A FRET-Based Fluorescent Probe to Screen Anticancer Drugs, Inhibiting p73 Binding to MDM2.

Chembiochem 2020 Oct 25. Epub 2020 Oct 25.

School of Pharmacy, Sungkyunkwan University, Suwon, 16419 (Republic of, Korea.

View Article and Find Full Text PDF
October 2020

Photoconjugation of an Fc-Specific Peptide Enables Efficient DAR 2 Antibody-Drug Conjugate Formation.

Org Lett 2020 11 19;22(21):8419-8423. Epub 2020 Oct 19.

School of Pharmacy, Sungkyunkwan University, Suwon 16419, South Korea.

View Article and Find Full Text PDF
November 2020

Phytosynthesis of Palladium Nanoclusters: An Efficient Nanozyme for Ultrasensitive and Selective Detection of Reactive Oxygen Species.

Molecules 2020 Jul 23;25(15). Epub 2020 Jul 23.

School of Pharmacy, Sungkyunkwan University, 2066 Seoburo, Jangan-gu, Suwon, Gyeonggido 16419, Korea.

View Article and Find Full Text PDF
July 2020

Enzyme Mimetic Activity of ZnO-Pd Nanosheets Synthesized via a Green Route.

Molecules 2020 Jun 2;25(11). Epub 2020 Jun 2.

School of Pharmacy, Sungkyunkwan University, 2066 Seoburo, Jangan-gu, Suwon, Gyeonggido 16419, Korea.

View Article and Find Full Text PDF
June 2020

Reclamation of hexavalent chromium using catalytic activity of highly recyclable biogenic Pd(0) nanoparticles.

Sci Rep 2020 01 20;10(1):640. Epub 2020 Jan 20.

School of Pharmacy, Sungkyunkwan University, 2066 Seoburo, Jangan-gu, Suwon, Gyeonggido, 16419, Republic of Korea.

View Article and Find Full Text PDF
January 2020

Facile Synthesis of Triangular and Hexagonal Anionic Gold Nanoparticles and Evaluation of Their Cytotoxicity.

Nanomaterials (Basel) 2019 Dec 12;9(12). Epub 2019 Dec 12.

School of Pharmacy, Sungkyunkwan University, 2066 Seoburo, Jangan-gu, Suwon, Gyeonggido 16419, Korea.

View Article and Find Full Text PDF
December 2019

Identification of Vaccinia-H1 Related Phosphatase as an Anticancer Target for 1,2,3,4,6-O-Pentagalloylglucose.

Chem Biodivers 2020 Feb 7;17(2):e1900414. Epub 2020 Jan 7.

School of Pharmacy, Sungkyunkwan University, Suwon, 16419, Republic of Korea.

View Article and Find Full Text PDF
February 2020

Coenzyme Q alleviates tacrolimus-induced mitochondrial dysfunction in kidney.

FASEB J 2019 11 20;33(11):12288-12298. Epub 2019 Aug 20.

Department of Internal Medicine and The Catholic University of Korea School of Medicine, Seoul, South Korea.

View Article and Find Full Text PDF
November 2019

Site-Selective C-H Alkylation of Diazine -Oxides Enabled by Phosphonium Ylides.

Org Lett 2019 08 2;21(16):6488-6493. Epub 2019 Aug 2.

School of Pharmacy , Sungkyunkwan University , Suwon 16419 , Republic of Korea.

View Article and Find Full Text PDF
August 2019

Chemical constituents of the root bark of Ulmus davidiana var. japonica and their potential biological activities.

Bioorg Chem 2019 10 25;91:103145. Epub 2019 Jul 25.

School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea. Electronic address:

View Article and Find Full Text PDF
October 2019

Identification of chebulinic acid as a dual targeting inhibitor of protein tyrosine phosphatases relevant to insulin resistance.

Bioorg Chem 2019 09 2;90:103087. Epub 2019 Jul 2.

School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea. Electronic address:

View Article and Find Full Text PDF
September 2019

Biogenic nanomaterials: Synthesis, characterization, growth mechanism, and biomedical applications.

J Microbiol Methods 2019 02 13;157:65-80. Epub 2018 Dec 13.

School of Pharmacy, Sungkyunkwan University, 2066 Seoburo, Jangan-gu, Suwon, Gyeonggido 16419, Republic of Korea. Electronic address:

View Article and Find Full Text PDF
February 2019

Ginkgetin, a biflavone from Ginkgo biloba leaves, prevents adipogenesis through STAT5-mediated PPARγ and C/EBPα regulation.

Pharmacol Res 2019 01 22;139:325-336. Epub 2018 Nov 22.

Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, Republic of Korea; Department of Biomolecular Science, University of Science & Technology (UST), Daejeon, Republic of Korea. Electronic address:

View Article and Find Full Text PDF
January 2019

Ginkgolic acid as a dual-targeting inhibitor for protein tyrosine phosphatases relevant to insulin resistance.

Bioorg Chem 2018 12 12;81:264-269. Epub 2018 Aug 12.

School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea. Electronic address:

View Article and Find Full Text PDF
December 2018

Fc-Binding Ligands of Immunoglobulin G: An Overview of High Affinity Proteins and Peptides.

Materials (Basel) 2016 Dec 8;9(12). Epub 2016 Dec 8.

Research Institute of Biomolecular Chemistry, Dongguk University, Seoul 100-715, Korea.

View Article and Find Full Text PDF
December 2016

Identification of sennoside A as a novel inhibitor of the slingshot (SSH) family proteins related to cancer metastasis.

Pharmacol Res 2017 05 6;119:422-430. Epub 2017 Mar 6.

Department of Chemistry, Dongguk University, Seoul 100-715, Republic of Korea; Research Institute of Biomolecular Chemistry, Dongguk University, Seoul 100-715, Republic of Korea. Electronic address:

View Article and Find Full Text PDF
May 2017

Real-time and label-free monitoring of nanoparticle cellular uptake using capacitance-based assays.

Sci Rep 2016 09 19;6:33668. Epub 2016 Sep 19.

Center for Nano-Bio Measurement, Korea Research Institute of Standards and Science Daejeon, Republic of Korea.

View Article and Find Full Text PDF
September 2016

Cyclic peptide ligand with high binding capacity for affinity purification of immunoglobulin G.

J Chromatogr A 2016 Sep 3;1466:105-12. Epub 2016 Sep 3.

Research Institute of Biomolecular Chemistry, Dongguk University, Seoul 100-715, Republic of Korea; Department of Chemistry, Dongguk University, Seoul 100-715, Republic of Korea. Electronic address:

View Article and Find Full Text PDF
September 2016

Mitochondria-Targeting Chromogenic and Fluorescence Turn-On Probe for the Selective Detection of Cysteine by Caged Oxazolidinoindocyanine.

Anal Chem 2016 07 1;88(14):7178-82. Epub 2016 Jul 1.

Department of Chemistry, Hankuk University of Foreign Studies , Yongin 17035, Republic of Korea.

View Article and Find Full Text PDF
July 2016

Recent Advances in pH-Sensitive Polymeric Nanoparticles for Smart Drug Delivery in Cancer Therapy.

Curr Drug Targets 2018 02;19(4):300-317

Department of Chemistry and Molecular Targeting Research Center, Dongguk University, Seoul 100-715, Korea.

View Article and Find Full Text PDF
February 2018

Functionalized protein nanocages as a platform of targeted therapy and immunodetection.

Nanomedicine (Lond) 2015 9;10(24):3579-95. Epub 2015 Dec 9.

Department of Chemistry, Dongguk University, Seoul 100-715, Republic of Korea.

View Article and Find Full Text PDF
September 2016

Phosphoprotein phosphatase 1CB (PPP1CB), a novel adipogenic activator, promotes 3T3-L1 adipogenesis.

Biochem Biophys Res Commun 2015 Nov 9;467(2):211-7. Epub 2015 Oct 9.

Research Institute of Biomolecular Chemistry, Dongguk University, Seoul 100-715, Republic of Korea. Electronic address:

View Article and Find Full Text PDF
November 2015

A lactate-induced response to hypoxia.

Cell 2015 Apr 16;161(3):595-609. Epub 2015 Apr 16.

Medical Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 305-806, Korea; Ochang Branch Institute, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 305-806, Korea; Department of Functional Genomics, Korea University of Science and Technology, Daejeon 305-350, Korea. Electronic address:

View Article and Find Full Text PDF
April 2015

Stimulation of angiogenesis and survival of endothelial cells by human monoclonal Tie2 receptor antibody.

Biomaterials 2015 May 17;51:119-128. Epub 2015 Feb 17.

Functional Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea; Department of Biomolecular Science, University of Science & Technology, Daejeon, Republic of Korea. Electronic address:

View Article and Find Full Text PDF
May 2015

Intrinsic tryptophan fluorescence in the detection and analysis of proteins: a focus on Förster resonance energy transfer techniques.

Int J Mol Sci 2014 Dec 5;15(12):22518-38. Epub 2014 Dec 5.

Department of Chemistry, Dongguk University, Seoul 100-715, Korea.

View Article and Find Full Text PDF
December 2014

Homogeneous detection of caspase-3 using intrinsic fluorescence resonance energy transfer (iFRET).

Biosens Bioelectron 2015 May 3;67:413-8. Epub 2014 Sep 3.

Research Institute for Biomolecular Chemistry, Dongguk University, Seoul 100-715, Republic of Korea; Department of Chemistry, Dongguk University, Seoul 100-715, Republic of Korea. Electronic address:

View Article and Find Full Text PDF
May 2015

Recent advances in target characterization and identification by photoaffinity probes.

Molecules 2013 Aug 29;18(9):10425-51. Epub 2013 Aug 29.

BioNanotechnology Research Center, KRIBB, 125 Kwahangno, Yuseong, Daejeon 305-806, Korea.

View Article and Find Full Text PDF
August 2013

Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates.

Acta Crystallogr D Biol Crystallogr 2013 Aug 19;69(Pt 8):1522-9. Epub 2013 Jul 19.

Medical Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, 111 Gwahangno, Yuseong-gu, Daejeon 305-806, Republic of Korea.

View Article and Find Full Text PDF
August 2013

Structural asymmetry of procaspase-7 bound to a specific inhibitor.

Acta Crystallogr D Biol Crystallogr 2013 Aug 18;69(Pt 8):1514-21. Epub 2013 Jul 18.

Department of Chemistry, College of Natural Science, Dongguk University, 26 Pil-dong 3-ga, Jung-gu, Seoul 100-715, Republic of Korea.

View Article and Find Full Text PDF
August 2013

Crystal structure of xenotropic murine leukaemia virus-related virus (XMRV) ribonuclease H.

Biosci Rep 2012 Oct;32(5):455-63

Medical Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Yuseong-Gu, Daejeon, Republic of Korea.

View Article and Find Full Text PDF
October 2012

Fabrication of nanoporous TiO2 hollow capsules using core-shell silica nanoparticle templates.

J Nanosci Nanotechnol 2012 Feb;12(2):1604-7

Center for Nanoscience and Quantum Metrology, KRISS, Daejeon 305-600, Korea.

View Article and Find Full Text PDF
February 2012

A selective Seoul-Fluor-based bioprobe, SfBP, for vaccinia H1-related phosphatase--a dual-specific protein tyrosine phosphatase.

Chem Commun (Camb) 2012 Jul 24;48(52):6553-5. Epub 2012 May 24.

BioNanotechnology Research Center, KRIBB and NanoBio Major, UST, 111 Kwahangno, Yuseong, Daejeon 305-806, Korea.

View Article and Find Full Text PDF
July 2012

Developing an antibody-binding protein cage as a molecular recognition drug modular nanoplatform.

Biomaterials 2012 Jul 28;33(21):5423-30. Epub 2012 Apr 28.

BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB) Daejeon 305-806, Republic of Korea.

View Article and Find Full Text PDF
July 2012

Color-tunable photoluminescent fullerene nanoparticles.

Adv Mater 2012 Apr 19;24(15):1999-2003. Epub 2012 Mar 19.

BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, School of Engineering, University of Science and Technology, Daejeon, South Korea.

View Article and Find Full Text PDF
April 2012

Identification of 3-acyl-2-phenylamino-1,4-dihydroquinolin-4-one derivatives as inhibitors of the phosphatase SerB653 in Porphyromonas gingivalis, implicated in periodontitis.

Bioorg Med Chem Lett 2012 Mar 21;22(5):2084-8. Epub 2012 Jan 21.

Medical Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, 52 Eoeun-Dong, Yuseong-Gu, Daejeon 305-600, Republic of Korea.

View Article and Find Full Text PDF
March 2012

Photoreversible cellular imaging using photochrome-conjugated fullerene silica nanoparticles.

Chem Commun (Camb) 2011 Oct 2;47(38):10668-70. Epub 2011 Sep 2.

BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Gwahangno, Yuseong, Daejeon 305-806, Republic of Korea.

View Article and Find Full Text PDF
October 2011

Modulation of exosome-mediated mRNA turnover by interaction of GTP-binding protein 1 (GTPBP1) with its target mRNAs.

FASEB J 2011 Aug 22;25(8):2757-69. Epub 2011 Apr 22.

Department of Life Science, Division of Molecular and Life Science, Pohang University of Science and Technology, Pohang, South Korea.

View Article and Find Full Text PDF
August 2011

Recent advances in protein tyrosine phosphatase detection using chemical probes.

Anticancer Agents Med Chem 2011 Jan;11(1):54-63

College of Pharmacy, Dongguk University-Seoul, Seoul 100-71, Korea.

View Article and Find Full Text PDF
January 2011

Development of a nanoparticle-based FRET sensor for ultrasensitive detection of phytoestrogen compounds.

Analyst 2010 Nov 28;135(11):2879-86. Epub 2010 Sep 28.

Korea Research Institute of Biosciences and Biotechnology (KRIBB), 111 Gwahangno, Yuseong-gu, Daejeon, 305-806, Korea.

View Article and Find Full Text PDF
November 2010

An iminocoumarin-based fluorescent probe for the selective detection of dual-specific protein tyrosine phosphatases.

Chemistry 2010 May;16(18):5297-300

Department of Chemistry, Dankook University, 126 Jukjeon-dong, Yongin-si, Gyeonggi-do 448-701, Korea.

View Article and Find Full Text PDF
May 2010

Efficient selection of IgG Fc domain-binding peptides fused to fluorescent protein using E. coli expression system and dot-blotting assay.

Peptides 2010 Feb 16;31(2):202-6. Epub 2009 Dec 16.

BioNanotechnology Research Center, KRIBB and Nanobiotechnology Division of UST Daejeon, Republic of Korea.

View Article and Find Full Text PDF
February 2010

Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor.

FASEB J 2010 Feb 26;24(2):560-9. Epub 2009 Oct 26.

Medical Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, 52 Eoeun-Dong, Yuseong-Gu, Daejeon, 305-600, Korea.

View Article and Find Full Text PDF
February 2010

Monitoring of cleavage preference for caspase-3 using recombinant protein substrates.

J Microbiol Biotechnol 2009 Sep;19(9):911-7

BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-333, Korea.

View Article and Find Full Text PDF
September 2009

A highly selective fluorescent ESIPT probe for the dual specificity phosphatase MKP-6.

Chem Commun (Camb) 2009 Oct 17(39):5895-7. Epub 2009 Aug 17.

Department of Chemistry, Dankook University, 126 Jukjeon-dong, Yongin-si, Gyeonggi-do, 448-701, Korea.

View Article and Find Full Text PDF
October 2009

Large-scale expression in Escherichia coli and efficient purification of precursor and active caspase-7 by introduction of thrombin cleavage sites.

Protein Expr Purif 2010 Jan 25;69(1):29-33. Epub 2009 Sep 25.

BioNanotechnology Research Center, KRIBB, Yusung, Daejeon 305-806, South Korea.

View Article and Find Full Text PDF
January 2010

Cascade enzyme-linked immunosorbent assay (CELISA).

Biosens Bioelectron 2009 Oct 18;25(2):332-7. Epub 2009 Jul 18.

BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Yuseong, Daejeon 305-333, Republic of Korea.

View Article and Find Full Text PDF
October 2009

Large-scale preparation of active caspase-3 in E. coli by designing its thrombin-activatable precursors.

BMC Biotechnol 2008 Dec 11;8:92. Epub 2008 Dec 11.

Nanobiotechnology Division, University of Science and Technology, Yuseong, Daejeon, 305-806, Korea.

View Article and Find Full Text PDF
December 2008

An ISFET biosensor for the monitoring of maltose-induced conformational changes in MBP.

FEBS Lett 2009 Jan 6;583(1):157-62. Epub 2008 Dec 6.

BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 305-333, South Korea.

View Article and Find Full Text PDF
January 2009

A potent reporter applicable to the monitoring of caspase-3-dependent proteolytic cleavage.

J Biotechnol 2008 Nov 15;138(1-2):17-23. Epub 2008 Aug 15.

BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Eoeun-Dong, Yuseong-Gu, Daejeon 305-333, Republic of Korea.

View Article and Find Full Text PDF
November 2008

Mixed self-assembly of polydiacetylenes for highly specific and sensitive strip biosensors.

Biosens Bioelectron 2008 Nov 18;24(3):480-4. Epub 2008 Jun 18.

BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Yuseong, Daejeon, Republic of Korea.

View Article and Find Full Text PDF
November 2008

Structure of human alpha-enolase (hENO1), a multifunctional glycolytic enzyme.

Acta Crystallogr D Biol Crystallogr 2008 Jun 14;64(Pt 6):651-7. Epub 2008 May 14.

BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology and Division of Nanobiotechnology, Korea University of Science and Technology (UST), Yuseong, Daejeon 305-333, Republic of Korea.

View Article and Find Full Text PDF
June 2008

Directed immobilization of DNA-binding proteins on a cognate DNA-modified chip surface.

J Biotechnol 2008 May 2;135(1):16-21. Epub 2008 Mar 2.

BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, 52 Eoeun-Dong, Yuseong-Gu, Daejeon 305-333, Republic of Korea.

View Article and Find Full Text PDF
May 2008

Synthesis and anticancer activity of geldanamycin derivatives derived from biosynthetically generated metabolites.

Org Biomol Chem 2008 Jan 30;6(2):340-8. Epub 2007 Nov 30.

Korea Research Institute of Bioscience & Biotechnology, 52 Eoeundong, Yuseonggu, Daejeon, 305-806, Korea.

View Article and Find Full Text PDF
January 2008

Stress-governed expression and purification of human type II hexokinase in Escherichia coli.

J Microbiol Biotechnol 2007 Apr;17(4):638-43

BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-600, Korea.

View Article and Find Full Text PDF
April 2007

Controlled antibody immobilization onto immunoanalytical platforms by synthetic peptide.

Anal Biochem 2008 Mar 23;374(1):99-105. Epub 2007 Oct 23.

BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Yuseong, Daejeon 305-333, Korea.

View Article and Find Full Text PDF
March 2008

Structure of human cytidine deaminase bound to a potent inhibitor.

J Med Chem 2005 Feb;48(3):658-60

Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.

View Article and Find Full Text PDF
February 2005

Structures of end products resulting from lesion processing by a DNA glycosylase/lyase.

Chem Biol 2004 Dec;11(12):1643-9

Department of Chemistry and Chemical Biology, Cambridge, Massachusetts 02138, USA.

View Article and Find Full Text PDF
December 2004

Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase.

Biochemistry 2003 Feb;42(6):1564-72

Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.

View Article and Find Full Text PDF
February 2003

Cleavage of beta-lactone ring by serine protease. Mechanistic implications.

Bioorg Med Chem 2002 Aug;10(8):2553-60

Division of Molecular and Life Sciences, Center for Integrated Molecular Systems, Pohang University of Science and Technology, San 31 Hyojadong, Pohang, South Korea 790-784.

View Article and Find Full Text PDF
August 2002

Insight into the stereochemistry in the inhibition of carboxypeptidase A with N-(hydroxyaminocarbonyl)phenylalanine: binding modes of an enantiomeric pair of the inhibitor to carboxypeptidase A.

Bioorg Med Chem 2002 Jun;10(6):2015-22

National Research Laboratory for Protein Engineering, Pohang University of Science and Technology, San 31Hyoja-dong, 790-784, Pohang, Republic of Korea.

View Article and Find Full Text PDF
June 2002