Sang Bae Han

Suppression of Pax3-MITF-M Axis Protects from UVB-Induced Skin Pigmentation by Tetrahydroquinoline Carboxamide.

Authors:

Yong-Pyo Choi Ga Hyun Kim Song-Hee Kim Jongseo Maeng Heesoon Lee Sang-Bae Han Ki Ho Kim Youngsoo Kim

Int J Mol Sci 2020 Dec 17;21(24). Epub 2020 Dec 17.

College of Pharmacy, Chungbuk National University, Cheongju 28160, Korea.

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December 2020

Recent Advances and Challenges in Controlling the Spatiotemporal Release of Combinatorial Anticancer Drugs from Nanoparticles.

Authors:

Moon Sup Yoon Yu Jin Lee Hee Ji Shin Chun-Woong Park Sang-Bae Han Jae-Kyung Jung Jin-Seok Kim Dae Hwan Shin

Pharmaceutics 2020 Nov 27;12(12). Epub 2020 Nov 27.

College of Pharmacy, Chungbuk National University, Cheongju 28160, Korea.

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November 2020

K284-6111 alleviates memory impairment and neuroinflammation in Tg2576 mice by inhibition of Chitinase-3-like 1 regulating ERK-dependent PTX3 pathway.

Authors:

Hyeon Joo Ham Yong Sun Lee Jaesuk Yun Dong Ju Son Hee Pom Lee Sang-Bae Han Jin Tae Hong

J Neuroinflammation 2020 Nov 22;17(1):350. Epub 2020 Nov 22.

College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju, Chungbuk, 28160, Republic of Korea.

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November 2020

G721-0282 exerts anxiolytic-like effects on chronic unpredictable mild stress in mice through inhibition of CHI3L1-mediated neuroinflammation.

Authors:

Hyeon Joo Ham Yong Sun Lee Hee Pom Lee Jaesung Cho Young Wan Ham Kwang Soo Lee Jaesuk Yun Sang Bae Han Jin Tae Hong

Br J Pharmacol 2020 Nov 3. Epub 2020 Nov 3.

College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju, Chungbuk, 28160, Republic of Korea.

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November 2020

Design, synthesis, and evaluation of novel -substituted-1-(4-chlorobenzyl)-1-indol-3-carbohydrazides as antitumor agents.

Authors:

Le Cong Huan Duong Tien Anh Pham-The Hai Lai Duc Anh Eun Jae Park A Young Ji Jong Soon Kang Do Thi Mai Dung Dao Thi Kim Oanh Truong Thanh Tung Dinh Thi Thanh Hai Sang-Bae Han Nguyen-Hai Nam

J Enzyme Inhib Med Chem 2020 Dec;35(1):1854-1865

Hanoi University of Pharmacy, Hanoi, Vietnam.

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December 2020

Phorbol ester activates human mesenchymal stem cells to inhibit B cells and ameliorate lupus symptoms in MRL. mice.

Authors:

Hong Kyung Lee Hyung Sook Kim Minji Pyo Eun Jae Park Sundong Jang Hye Won Jun Tae Yong Lee Kyung Suk Kim Sang-Cheol Bae Youngsoo Kim Jin Tae Hong Jaesuk Yun Sang-Bae Han

Theranostics 2020 13;10(22):10186-10199. Epub 2020 Aug 13.

College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk 28160, Republic of Korea.

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August 2020

Design, synthesis and evaluation of novel indirubin-based N-hydroxybenzamides, N-hydroxypropenamides and N-hydroxyheptanamides as histone deacetylase inhibitors and antitumor agents.

Authors:

Duong Tien Anh Pham-The Hai Do Thi Mai Dung Phan Thi Phuong Dung Le-Thi-Thu Huong Eun Jae Park Hye Won Jun Jong Soon Kang Joo-Hee Kwon Truong Thanh Tung Sang-Bae Han Nguyen-Hai Nam

Bioorg Med Chem Lett 2020 Nov 8;30(22):127537. Epub 2020 Sep 8.

Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Viet Nam. Electronic address:

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November 2020

Antifungal drug miconazole ameliorated memory deficits in a mouse model of LPS-induced memory loss through targeting iNOS.

Authors:

In Jun Yeo Jaesuk Yun Dong Ju Son Sang-Bae Han Jin Tae Hong

Cell Death Dis 2020 08 14;11(8):623. Epub 2020 Aug 14.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31 Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju, Chungbuk, 28160, Republic of Korea.

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August 2020

A novel de novo heterozygous DYRK1A mutation causes complete loss of DYRK1A function and developmental delay.

Authors:

Kyu-Sun Lee Miri Choi Dae-Woo Kwon Doyoun Kim Jong-Moon Choi Ae-Kyeong Kim Youngwook Ham Sang-Bae Han Sungchan Cho Chong Kun Cheon

Sci Rep 2020 06 17;10(1):9849. Epub 2020 Jun 17.

Division of Medical Genetics and Metabolism, Department of Pediatrics, Pusan National University Children's Hospital, Pusan National University School of Medicine, 20 Geumo-ro, Mulgeum-eup, Yangsan-si, Gyeongnam, 50612, Republic of Korea.

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June 2020

Exploration of certain 1,3-oxazole- and 1,3-thiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents.

Authors:

Duong Tien Anh Pham-The Hai Le-Thi-Thu Huong Eun Jae Park Hye Won Jun Jong Soon Kang Joo-Hee Kwon Do Thi Mai Dung Vu Tran Anh Van Thi My Hue Sang-Bae Han Nguyen-Hai Nam

Bioorg Chem 2020 08 1;101:103988. Epub 2020 Jun 1.

Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Viet Nam. Electronic address:

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August 2020

Design, Synthesis and Bioevaluation of Two Series of 3-[(1-Benzyl-1H-1,2,3-triazol-4-yl)methyl]quinazolin-4(3H)-ones and N-(1-Benzylpiperidin-4-yl)quinazolin-4-amines.

Authors:

Ta Thu Lan Duong Tien Anh Hai Pham-The Do Thi Mai Dung Eun Jae Park Sun Dong Jang Joo Hee Kwon Jong Soon Kang Nguyen Thi Thuan Sang-Bae Han Nguyen-Hai Nam

Chem Biodivers 2020 Jul 23;17(7):e2000290. Epub 2020 Jun 23.

Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, 10000, Vietnam.

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July 2020

FlexPro MD®, a Combination of Krill Oil, Astaxanthin and Hyaluronic Acid, Reduces Pain Behavior and Inhibits Inflammatory Response in Monosodium Iodoacetate-Induced Osteoarthritis in Rats.

Authors:

Min Hee Park Jae Chul Jung Stephen Hill Elizabeth Cartwright Margaret H Dohnalek Min Yu Hee Joon Jun Sang Bae Han Jin Tae Hong Dong Ju Son

Nutrients 2020 Mar 30;12(4). Epub 2020 Mar 30.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-21 Osongsaengmyeong 1-ro, Osong-eup, Heungduk-gu, Cheongju, Chungbuk 28160, Korea.

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March 2020

Effect of Human Mesenchymal Stem Cells on Xenogeneic T and B Cells Isolated from Lupus-Prone MRL Mice.

Authors:

Hong Kyung Lee Eun Young Kim Hyung Sook Kim Eun Jae Park Hye Jin Lee Tae Yong Lee Kyung Suk Kim Sang-Cheol Bae Jin Tae Hong Youngsoo Kim Sang-Bae Han

Stem Cells Int 2020 5;2020:5617192. Epub 2020 Mar 5.

College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk 28160, Republic of Korea.

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March 2020

Peroxiredoxin 6 mediates acetaminophen-induced hepatocyte death through JNK activation.

Authors:

Dong Hun Lee Young Suk Jung Jaesuk Yun Sang Bae Han Yoon Seok Roh Min Jong Song Jin Tae Hong

Redox Biol 2020 05 8;32:101496. Epub 2020 Mar 8.

College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro 194-31, Osong-eup, Heungduk-gu, Cheongju, Chungbuk, 28160, Republic of Korea. Electronic address:

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May 2020

Prevention of multiple system atrophy using human bone marrow-derived mesenchymal stem cells by reducing polyamine and cholesterol-induced neural damages.

Authors:

Kyung-Ran Park Chul Ju Hwang Hyung-Mun Yun In Jun Yeo Dong-Young Choi Pil-Hoon Park Hyung Sook Kim Jung Tae Lee Young Suk Jung Sang-Bae Han Jin Tae Hong

Stem Cell Res Ther 2020 03 4;11(1):63. Epub 2020 Mar 4.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31, Osongsangmyeong1-ro, Heungdeok-gu, Cheongju, Chungbuk, 361-951, Republic of Korea.

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March 2020

Chitinase 3 like 1 suppresses the stability and activity of p53 to promote lung tumorigenesis.

Authors:

Kyung-Ran Park Hyung-Mun Yun Kyeongwon Yoo Young Wan Ham Sang Bae Han Jin Tae Hong

Cell Commun Signal 2020 03 4;18(1). Epub 2020 Mar 4.

College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro 194-21, Osong-eup, Heungduk-gu, Cheongju, Chungbuk, 361-951, Republic of Korea.

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March 2020

Anxiolytic-like effects of the ethanol extract of Magnolia obovata leaves through its effects on GABA-benzodiazepine receptor and neuroinflammation.

Authors:

Hyeon Joo Ham Yong Sun Lee Jaesuk Yun Sang-Bae Han Dong Ju Son Jin Tae Hong

Behav Brain Res 2020 04 30;383:112518. Epub 2020 Jan 30.

College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju, Chungbuk, 28160, Republic of Korea. Electronic address:

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April 2020

New Acetohydrazides Incorporating 2-Oxoindoline and 4-Oxoquinazoline: Synthesis and Evaluation of Cytotoxicity and Caspase Activation Activity.

Authors:

Le Cong Huan Duong Tien Anh Bui Xuan Truong Phan Huy Duc Pham-The Hai Lai Duc-Anh Le-Thi-Thu Huong Eun Jae Park Hye Jin Lee Jong Soon Kang Phuong-Thao Tran Dinh Thi Thanh Hai Dao Thi Kim Oanh Sang-Bae Han Nguyen-Hai Nam

Chem Biodivers 2020 Mar 4;17(3):e1900670. Epub 2020 Feb 4.

Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, 10000, Vietnam.

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March 2020

IL-32γ suppressed atopic dermatitis through inhibition of miR-205 expression via inactivation of nuclear factor-kappa B.

Authors:

Yong Sun Lee Sang-Bae Han Hyeon Joo Ham Ju Ho Park Jong Sung Lee Dae Yeon Hwang Young Suk Jung Do Young Yoon Jin Tae Hong

J Allergy Clin Immunol 2020 Jul 10;146(1):156-168. Epub 2020 Jan 10.

College of Pharmacy and Medical Research Center, Chungbuk National University, Chungbuk, Korea. Electronic address:

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July 2020

Stem Cell Factor-Inducible MITF-M Expression in Therapeutics for Acquired Skin Hyperpigmentation.

Authors:

Cheong-Yong Yun Eunmiri Roh Song-Hee Kim Jinhe Han Jiyeon Lee Da-Eun Jung Ga Hyeon Kim Sang-Hun Jung Won-Jea Cho Sang-Bae Han Youngsoo Kim

Theranostics 2020 1;10(1):340-352. Epub 2020 Jan 1.

College of Pharmacy, Chungbuk National University, Cheongju 28160, Korea.

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January 2020

Mesenchymal Stem Cells Ameliorate Renal Inflammation in Adriamycin-induced Nephropathy.

Authors:

Hyung Sook Kim Jae Seob Lee Hong Kyung Lee Eun Jae Park Hye Won Jeon Yu Jeong Kang Tae Yong Lee Kyung Suk Kim Sang-Cheol Bae Ji Hyun Park Sang-Bae Han

Immune Netw 2019 Oct 14;19(5):e36. Epub 2019 Oct 14.

College of Pharmacy, Chungbuk National University, Cheongju 28160, Korea.

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October 2019

Deletion of Chitinase-3-like 1 accelerates stroke development through enhancement of Neuroinflammation by STAT6-dependent M2 microglial inactivation in Chitinase-3-like 1 knockout mice.

Authors:

Jun Hyung Im In Jun Yeo Pil Hoon Park Dong Young Choi Sang-Bae Han Jaesuk Yun Jin Tae Hong

Exp Neurol 2020 01 24;323:113082. Epub 2019 Oct 24.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-21, Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju-si, Chungcheongbuk-do, Republic of Korea. Electronic address:

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January 2020

Exosomal miR-181b-5p Downregulation in Ascites Serves as a Potential Diagnostic Biomarker for Gastric Cancer-associated Malignant Ascites.

Authors:

Jieun Yun Sang-Bae Han Hong Jun Kim Se-Il Go Won Sup Lee Woo Kyun Bae Sang-Hee Cho Eun-Kee Song Ok-Jun Lee Hee Kyung Kim Yaewon Yang Jihyun Kwon Hee Bok Chae Ki Hyeong Lee Hye Sook Han

J Gastric Cancer 2019 Sep 28;19(3):301-314. Epub 2019 Aug 28.

Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea.

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September 2019

Bee venom phospholipase A2 ameliorates amyloidogenesis and neuroinflammation through inhibition of signal transducer and activator of transcription-3 pathway in Tg2576 mice.

Authors:

Hyeon Joo Ham Sang-Bae Han Jaesuk Yun In Jun Yeo Young Wan Ham Se Hyun Kim Pil-Hoon Park Dong-Young Choi Jin Tae Hong

Transl Neurodegener 2019 2;8:26. Epub 2019 Oct 2.

1College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju, Chungbuk 28160 Republic of Korea.

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October 2019

Improvement of spinal muscular atrophy via correction of the SMN2 splicing defect by Brucea javanica (L.) Merr. extract and Bruceine D.

Authors:

Jiyeon Baek Hyejeong Jeong Youngwook Ham Yang Hee Jo Miri Choi Mingu Kang Bora Son Sangho Choi Hyung Won Ryu Janghwan Kim Haihong Shen Kongmany Sydara Sang Woo Lee Soo-Yong Kim Sang-Bae Han Sei-Ryang Oh Sungchan Cho

Phytomedicine 2019 Dec 16;65:153089. Epub 2019 Sep 16.

Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, Chungbuk 28116, Republic of Korea; Department of Biomolecular Science, KRIBB School of Bioscience, Korea University of Science and Technology, Daejeon 34113, Republic of Korea. Electronic address:

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December 2019

Novel 3,4-dihydro-4-oxoquinazoline-based acetohydrazides: Design, synthesis and evaluation of antitumor cytotoxicity and caspase activation activity.

Authors:

Le Cong Huan Phuong-Thao Tran Cao Viet Phuong Phan Huy Duc Duong Tien Anh Pham The Hai Le Thi Thu Huong Nguyen Thi Thuan Hye Jin Lee Eun Jae Park Jong Soon Kang Nguyen Phuong Linh Tran Trung Hieu Dao Thi Kim Oanh Sang-Bae Han Nguyen-Hai Nam

Bioorg Chem 2019 11 14;92:103202. Epub 2019 Aug 14.

Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Viet Nam. Electronic address:

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November 2019

Parkin deficiency prevents chronic ethanol-induced hepatic lipid accumulation through β-catenin accumulation.

Authors:

Dong Hun Lee Mi Hee Park Chul Ju Hwang Youngsoo Kim Dae Yeon Hwang Sang Bae Han Jin Tae Hong

Cell Commun Signal 2019 08 22;17(1):104. Epub 2019 Aug 22.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31 Osongsaengmyeong 1-ro, Osong-eup, Heungduk-gu, Cheongju, Chungbuk, 28160, Republic of Korea.

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August 2019

Roles of chitinase 3-like 1 in the development of cancer, neurodegenerative diseases, and inflammatory diseases.

Authors:

In Jun Yeo Chong-Kil Lee Sang-Bae Han Jaesuk Yun Jin Tae Hong

Pharmacol Ther 2019 11 26;203:107394. Epub 2019 Jul 26.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31, Osongsaengmyeong 1-ro, Osong-eup, Cheongju-si, Chungbuk 28160, Republic of Korea. Electronic address:

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November 2019

Inhibition of Lung Tumor Development in ApoE Knockout Mice via Enhancement of TREM-1 Dependent NK Cell Cytotoxicity.

Authors:

Yong Sun Lee In Jun Yeo Ki Cheon Kim Sang-Bae Han Jin Tae Hong

Front Immunol 2019 18;10:1379. Epub 2019 Jun 18.

College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju, South Korea.

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October 2020

IL-32γ suppresses lung cancer stem cell growth via inhibition of ITGAV-mediated STAT5 pathway.

Authors:

Yong Sun Lee Ki Cheon Kim Raj Kumar Mongre Ji Young Kim Yu Ri Kim Dong Young Choi Sukgil Song Jaesuk Yun Sang-Bae Han Do Young Yoon Jin Tae Hong

Cell Death Dis 2019 07 1;10(7):506. Epub 2019 Jul 1.

College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro, Osong-eup, Heungduk-gu, Cheongju, Chungbuk, 28160, Republic of Korea.

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July 2019

Combination Effect of Titrated Extract of and Astaxanthin in a Mouse Model of Phthalic Anhydride-Induced Atopic Dermatitis.

Authors:

Ju Ho Park In Jun Yeo Jun Sung Jang Ki Cheon Kim Mi Hee Park Hee Pom Lee Sang Bae Han Jin Tae Hong

Allergy Asthma Immunol Res 2019 Jul;11(4):548-559

College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju, Korea.

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July 2019

(E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) Phenol Ameliorates MPTP-Induced Dopaminergic Neurodegeneration by Inhibiting the STAT3 Pathway.

Authors:

Ji Yeon Choi Jaesuk Yun Chul Ju Hwang Hee Pom Lee Hae Deun Kim Hyungok Chun Pil-Hoon Park Dong Young Choi Sang-Bae Han Jin Tae Hong

Int J Mol Sci 2019 May 29;20(11). Epub 2019 May 29.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31 Osongsaemgmyeong 1-ro, Cheongju 28160, Korea.

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May 2019

Loss of parkin reduces lung tumor development by blocking p21 degradation.

Authors:

Kyung-Ran Park Jae Suk Yun Mi Hee Park Yu Yeon Jung In Jun Yeo Kyung Tak Nam Hae Deun Kim Ju Kyoung Song Dong-Young Choi Pil-Hoon Park Sang-Bae Han Hyung-Mun Yun Jin Tae Hong

PLoS One 2019 21;14(5):e0217037. Epub 2019 May 21.

College of Pharmacy and Medical Research Center, Chungbuk National University, Osong-eup, Heungduk-gu, Cheongju, Chungbuk, Republic of Korea.

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February 2020

Peroxiredoxin 6 Confers Protection Against Nonalcoholic Fatty Liver Disease Through Maintaining Mitochondrial Function.

Authors:

Dong Hun Lee Yu Yeon Jung Mi Hee Park Mi Ran Jo Sang Bae Han Do Young Yoon Yoon Seok Roh Jin Tae Hong

Antioxid Redox Signal 2019 08 22;31(5):387-402. Epub 2019 May 22.

1 College of Pharmacy and Medical Research Center, Department of Pharmacy Chungbuk National University, Cheongju, South Korea.

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August 2019

Chitinase-3-like-1 deficiency attenuates ethanol-induced liver injury by inhibition of sterol regulatory element binding protein 1-dependent triglyceride synthesis.

Authors:

Dong Hun Lee Ji Hye Han Yong Sun Lee Young Suk Jung Yoon Seok Roh Jae Suk Yun Sang Bae Han Jin Tae Hong

Metabolism 2019 06 29;95:46-56. Epub 2019 Mar 29.

College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju, Chungbuk 28160, Republic of Korea. Electronic address:

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June 2019

Decreased Lung Tumor Development in SwAPP Mice through the Downregulation of CHI3L1 and STAT 3 Activity via the Upregulation of miRNA342-3p.

Authors:

Dong Hun Lee Ki Cheon Kim Chul Ju Hwang Kyung Ran Park Young Suk Jung Sun Young Kim Ji Young Kim Ju Kyung Song Min Ji Song Min Ki Choi Dae Youn Hwang Sang-Bae Han Jin Tae Hong

Mol Ther Nucleic Acids 2019 Jun 20;16:63-72. Epub 2019 Feb 20.

College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro 194-21, Osong-eup, Heungduk-gu, Cheongju, Chungbuk 28160, Republic of Korea. Electronic address:

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June 2019

Nuclear Entry of CRTC1 as Druggable Target of Acquired Pigmentary Disorder.

Authors:

Cheong-Yong Yun Seung Deok Hong Young Hee Lee Jiyeon Lee Da-Eun Jung Ga Hyun Kim Song-Hee Kim Jae-Kyung Jung Ki Ho Kim Heesoon Lee Jin Tae Hong Sang-Bae Han Youngsoo Kim

Theranostics 2019 21;9(3):646-660. Epub 2019 Jan 21.

College of Pharmacy, Chungbuk National University, Cheongju 28160, Korea.

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December 2019

Astaxanthin Ameliorates Lipopolysaccharide-Induced Neuroinflammation, Oxidative Stress and Memory Dysfunction through Inactivation of the Signal Transducer and Activator of Transcription 3 Pathway.

Authors:

Ji Hye Han Yong Sun Lee Jun Hyung Im Young Wan Ham Hee Pom Lee Sang Bae Han Jin Tae Hong

Mar Drugs 2019 Feb 18;17(2). Epub 2019 Feb 18.

Department of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju, Chungbuk 28160, Korea.

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February 2019

(E)-N'-Arylidene-2-(4-oxoquinazolin-4(3H)-yl) acetohydrazides: Synthesis and evaluation of antitumor cytotoxicity and caspase activation activity.

Authors:

Le Cong Huan Cao Viet Phuong Le Cong Truc Vo Nguyen Thanh Hai Pham-The Le-Thi-Thu Huong Nguyen Thi Thuan Eun Jae Park A Young Ji Jong Soon Kang Sang-Bae Han Phuong-Thao Tran Nguyen-Hai Nam

J Enzyme Inhib Med Chem 2019 Dec;34(1):465-478

a Pharmaceutical Chemistry , Hanoi University of Pharmacy , Hanoi , Vietnam.

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December 2019

Quinazolin-4(3H)-one-Based Hydroxamic Acids: Design, Synthesis and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity.

Authors:

Doan Thanh Hieu Duong Tien Anh Pham-The Hai Nguyen Thi Thuan Le-Thi-Thu Huong Eun Jae Park A Young Ji Jong Soon Kang Phan Thi Phuong Dung Sang-Bae Han Nguyen-Hai Nam

Chem Biodivers 2019 Apr 21;16(4):e1800502. Epub 2019 Mar 21.

Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, 0084, Vietnam.

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April 2019

Characterization of morphological changes of B16 melanoma cells under natural killer cell attack.

Authors:

Ji Sung Kim Boyeong Kim Hong Kyung Lee Hyung Sook Kim Eun Jae Park Yeo Jin Choi Gi Beom Ahn Jieun Yun Jin Tae Hong Youngsoo Kim Sang-Bae Han

Int Immunopharmacol 2019 Feb 21;67:366-371. Epub 2018 Dec 21.

College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk 28160, Republic of Korea. Electronic address:

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February 2019

Inhibition of skin carcinogenesis by suppression of NF-κB dependent ITGAV and TIMP-1 expression in IL-32γ overexpressed condition.

Authors:

Yong Sun Lee Chung Hee Lee Jun Tae Bae Kyung Tak Nam Dae Bong Moon Ok Kyung Hwang Jeong Soon Choi Tae Hoon Kim Hyoung Ok Jun Young Suk Jung Dae Yeon Hwang Sang-Bae Han Do Young Yoon Jin Tae Hong

J Exp Clin Cancer Res 2018 Nov 28;37(1):293. Epub 2018 Nov 28.

College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju, Chungbuk, 28160, Republic of Korea.

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November 2018

Design, Synthesis and Evaluation of Novel 3/4-((Substituted benzamidophenoxy) methyl)-N-hydroxybenzamides/propenamides as Histone Deacetylase Inhibitors and Antitumor Agents.

Authors:

Duong T Anh Nguyen T Thuan Pham-The Hai Le-Thi-Thu Huong Nguyen T K Yen Byung W Han Eun J Park Yeo J Choi Jong S Kang Van T M Hue Sang-Bae Han Nguyen-Hai Nam

Anticancer Agents Med Chem 2019 ;19(4):546-556

Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Vietnam.

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February 2020

Astaxanthin alleviated ethanol-induced liver injury by inhibition of oxidative stress and inflammatory responses via blocking of STAT3 activity.

Authors:

Ji Hye Han Jung Heun Ju Yong Sun Lee Ju Ho Park In Jun Yeo Mi Hee Park Yoon Seok Roh Sang Bae Han Jin Tae Hong

Sci Rep 2018 09 20;8(1):14090. Epub 2018 Sep 20.

College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju, Chungbuk, 28160, Republic of Korea.

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September 2018

Suppression of metastasis through inhibition of chitinase 3-like 1 expression by miR-125a-3p-mediated up-regulation of USF1.

Authors:

Ki Cheon Kim Jaesuk Yun Dong Ju Son Ji Young Kim Jae-Kyung Jung Jeong Soon Choi Yu Ri Kim Ju Kyung Song Sun Young Kim Sin Kook Kang Dae Hwan Shin Yoon-Seok Roh Sang-Bae Han Jin Tae Hong

Theranostics 2018 7;8(16):4409-4428. Epub 2018 Aug 7.

College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro 194-21, Osong-eup, Heungduk-gu, Cheongju, Chungbuk, 28160, Republic of Korea.

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September 2019

K284-6111 prevents the amyloid beta-induced neuroinflammation and impairment of recognition memory through inhibition of NF-κB-mediated CHI3L1 expression.

Authors:

Ji Yeon Choi In Jun Yeo Ki Cheon Kim Won Rack Choi Jae-Kyung Jung Sang-Bae Han Jin Tae Hong

J Neuroinflammation 2018 Aug 11;15(1):224. Epub 2018 Aug 11.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31 Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju, Chungbuk, 28160, Republic of Korea.

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August 2018

PRDX6 Inhibits Neurogenesis through Downregulation of WDFY1-Mediated TLR4 Signal.

Authors:

In Jun Yeo Mi Hee Park Dong Ju Son Ji Young Kim Kyoung Tak Nam Byung Kook Hyun So Young Kim Myung Hee Jung Min Ji Song Hyung Ok Chun Tae Hyung Lee Sang-Bae Han Jin Tae Hong

Mol Neurobiol 2019 May 10;56(5):3132-3144. Epub 2018 Aug 10.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31, Osongsaengmyeong 1-ro, Heungdeok-gu, Cheongju, Chungbuk, 361-951, Republic of Korea.

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May 2019

CXCR3-deficient natural killer cells fail to migrate to B16F10 melanoma cells.

Authors:

Juyoung Kim Ji Sung Kim Hong Kyung Lee Hyung Sook Kim Eun Jae Park Jeong Eun Choi Yeo Jin Choi Bo Ram Shin Eun Young Kim Jin Tae Hong Youngsoo Kim Sang-Bae Han

Int Immunopharmacol 2018 Oct 31;63:66-73. Epub 2018 Jul 31.

College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk 28160, Republic of Korea. Electronic address:

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October 2018

Effect of a Combination of Prednisone or Mycophenolate Mofetil and Mesenchymal Stem Cells on Lupus Symptoms in MRL. Mice.

Authors:

Hong Kyung Lee Ki Hun Kim Hyung Sook Kim Ji Sung Kim Jae Hee Lee Ayoung Ji Kyung Suk Kim Tae Yong Lee In Young Chang Sang-Cheol Bae Jin Tae Hong Youngsoo Kim Sang-Bae Han

Stem Cells Int 2018 3;2018:4273107. Epub 2018 Jul 3.

College of Pharmacy, Chungbuk National University, Cheongju, 28160 Chungcheongbuk-do, Republic of Korea.

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July 2018

N'-[(E)-Arylidene]-2-(2,3-dihydro-3-oxo-4H-1,4-benzoxazin-4-yl)-acetohydrazides: Synthesis and Evaluation of Caspase Activation Activity and Cytotoxicity.

Authors:

Le Cong Huan Le Cong Truc Cao Viet Phuong Pham-The Hai Le-Thi-Thu Huong Nguyen Tran Phuong Linh Nguyen Thi Thuan Eun Jae Park Yeo Jin Choi Jong Soon Kang Sang-Bae Han Nguyen-Hai Nam Phuong-Thao Tran

Chem Biodivers 2018 Oct 24;15(10):e1800322. Epub 2018 Sep 24.

Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Vietnam.

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October 2018

Deficiency of parkin suppresses melanoma tumor development and metastasis through inhibition of MFN2 ubiquitination.

Authors:

Yong Sun Lee Yu Yeon Jung Mi Hee Park In Jun Yeo Hyung Sik Im Kyung Tak Nam Hae Deun Kim Shin Kook Kang Ju Koung Song Yu Ri Kim Dong-Young Choi Pil-Hoon Park Sang-Bae Han Jae Suk Yun Jin Tae Hong

Cancer Lett 2018 10 5;433:156-164. Epub 2018 Jul 5.

College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro 194-21, Osong-eup, Heungduk-gu, Cheongju, Chungbuk, 28160, Republic of Korea. Electronic address:

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October 2018

Facile analysis of protein-protein interactions in living cells by enriched visualization of the p-body.

Authors:

Miri Choi Jiyeon Baek Sang-Bae Han Sungchan Cho

BMB Rep 2018 Oct;51(10):526-531

Anticancer Agent Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju 28116, South Korea; Department of Biomolecular Science, KRIBB School of Bioscience, Korea University of Science and Technology, Daejeon 34113, South Korea.

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October 2018

Novel Hydroxamic Acids Incorporating 1-((1H-1,2,3-Triazol-4-yl)methyl)- 3-substituted-2-oxoindolines: Synthesis, Biological Evaluation and SAR Analysis.

Authors:

Do T M Dung Nguyen V Huan Do M Cam Dao C Hieu Pham-The Hai Le-Thi-Thu Huong Jisung Kim Jeong E Choi Jong S Kang Sang-Bae Han Nguyen-Hai Nam

Med Chem 2018 ;14(8):831-850

Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Vietnam.

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March 2019

Piperlongumine Improves Lipopolysaccharide-Induced Amyloidogenesis by Suppressing NF-KappaB Pathway.

Authors:

Sun Mi Gu Hee Pom Lee Young Wan Ham Dong Ju Son Hoi Yeong Kim Ki Wan Oh Sang-Bae Han Jaesuk Yun Jin Tae Hong

Neuromolecular Med 2018 09 25;20(3):312-327. Epub 2018 May 25.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31 Osongsaemgmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju-si, Chungbuk, 28160, Republic of Korea.

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September 2018

Estrogen deficiency exacerbates Aβ-induced memory impairment through enhancement of neuroinflammation, amyloidogenesis and NF-ĸB activation in ovariectomized mice.

Authors:

Jaesuk Yun In Jun Yeo Chul Ju Hwang Dong-Young Choi Hyung-Sik Im Ji Youg Kim Won Rak Choi Myung Hee Jung Sang-Bae Han Jin Tae Hong

Brain Behav Immun 2018 10 18;73:282-293. Epub 2018 May 18.

College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro 194-31, Osong-eup, Heungduk-gu, Cheongju, Chungbuk 28160, Republic of Korea. Electronic address:

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October 2018

Quinazoline-Based Hydroxamic Acids: Design, Synthesis, and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity.

Authors:

Doan Thanh Hieu Duong Tien Anh Pham-The Hai Le-Thi-Thu Huong Eun Jae Park Jeong Eun Choi Jong Soon Kang Phan Thi Phuong Dung Sang-Bae Han Nguyen-Hai Nam

Chem Biodivers 2018 Jun 1;15(6):e1800027. Epub 2018 Jun 1.

Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Vietnam.

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June 2018

Testing Cell-Based Immunotherapy for Colorectal Cancer.

Authors:

Jong Soon Kang Yeo Dae Yoon Myeong Youl Lee Chang Woo Lee Suk Jong Lee Sang-Bae Han

Methods Mol Biol 2018 ;1765:299-305

College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.

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January 2019

α-Viniferin Improves Facial Hyperpigmentation via Accelerating Feedback Termination of cAMP/PKA-Signaled Phosphorylation Circuit in Facultative Melanogenesis.

Authors:

Cheong-Yong Yun Seon Mi Ko Yong Pyo Choi Beom Joon Kim Jungno Lee Jae Mun Kim Ju Yeon Kim Jin Yong Song Song-Hee Kim Bang Yeon Hwang Jin Tae Hong Sang-Bae Han Youngsoo Kim

Theranostics 2018 16;8(7):2031-2043. Epub 2018 Feb 16.

College of Pharmacy, Chungbuk National University, Cheongju 28160, Korea.

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February 2019

IL-32 gamma reduces lung tumor development through upregulation of TIMP-3 overexpression and hypomethylation.

Authors:

Jaesuk Yun Mi Hee Park Dong Ju Son Kyung Tak Nam Dae Bong Moon Jung Heun Ju Ok Kyung Hwang Jeong Soon Choi Tae Hoon Kim Young Suk Jung Dae Yeon Hwang Sang Bae Han Do-Young Yoon Jin Tae Hong

Cell Death Dis 2018 02 21;9(3):306. Epub 2018 Feb 21.

College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong1-ro 194-21, Heungduk-gu, Cheongju, Chungbuk, 28160, Republic of Korea.

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February 2018

Small activating RNA induced expression of VHL gene in renal cell carcinoma.

Authors:

Moo Rim Kang Ki Hwan Park Chang Woo Lee Myeong Youl Lee Sang-Bae Han Long-Cheng Li Jong Soon Kang

Int J Biochem Cell Biol 2018 04 6;97:36-42. Epub 2018 Feb 6.

Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, 30 Yeongudanjiro, Cheongju, 28116, Republic of Korea. Electronic address:

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April 2018

Atherosclerosis is exacerbated by chitinase-3-like-1 in amyloid precursor protein transgenic mice.

Authors:

Yu Yeon Jung Ki Cheon Kim Mi Hee Park Youngsik Seo Heonyong Park Min Hee Park Jun Chang Dae Youn Hwang Sang Bae Han Sanghyeon Kim Dong Ju Son Jin Tae Hong

Theranostics 2018 1;8(3):749-766. Epub 2018 Jan 1.

College of Pharmacy & Medical Research Center, Chungbuk National University, Cheongju, Chungbuk 28160, Korea.

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December 2018

Design, synthesis and evaluation of novel N-hydroxybenzamides/N-hydroxypropenamides incorporating quinazolin-4(3H)-ones as histone deacetylase inhibitors and antitumor agents.

Authors:

Doan Thanh Hieu Duong Tien Anh Nguyen Minh Tuan Pham-The Hai Le-Thi-Thu Huong Jisung Kim Jong Soon Kang Tran Khac Vu Phan Thi Phuong Dung Sang-Bae Han Nguyen-Hai Nam Nguyen-Dang Hoa

Bioorg Chem 2018 02 5;76:258-267. Epub 2017 Dec 5.

Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Viet Nam. Electronic address:

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February 2018

A small molecule, (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol suppresses tumor growth via inhibition of IkappaB kinase β in colorectal cancer and .

Authors:

Jie Zheng Mi Hee Park Hee Pom Lee Byung Kook Hyun Hyung Ok Chun Sung Hee Jung Hyun Ok Seo Young Wan Ham Sang-Bae Han Jin Tae Hong

Oncotarget 2017 Oct 24;8(53):91258-91269. Epub 2017 Aug 24.

College of Pharmacy & Medical Research Center, Chungbuk National University, Cheongju, Chungbuk 28160, Republic of Korea.

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October 2017

Antarctic Krill Oil Diet Protects against Lipopolysaccharide-Induced Oxidative Stress, Neuroinflammation and Cognitive Impairment.

Authors:

Ji Yeon Choi Jun Sung Jang Dong Ju Son Hyung-Sik Im Ji Yeong Kim Joung Eun Park Won Rak Choi Sang-Bae Han Jin Tae Hong

Int J Mol Sci 2017 Nov 28;18(12). Epub 2017 Nov 28.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31 Osongsaemgmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju 28160, Chungbuk, Korea.

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November 2017

MMPP Attenuates Non-Small Cell Lung Cancer Growth by Inhibiting the STAT3 DNA-Binding Activity Direct Binding to the STAT3 DNA-Binding Domain.

Authors:

Dong Ju Son Jie Zheng Yu Yeon Jung Chul Ju Hwang Hee Pom Lee Ju Rang Woo Song Yi Baek Young Wan Ham Min Woong Kang Minho Shong Gi Ryang Kweon Min Jong Song Jae Kyung Jung Sang-Bae Han Bo Yeon Kim Do Young Yoon Bu Young Choi Jin Tae Hong

Theranostics 2017 16;7(18):4632-4642. Epub 2017 Oct 16.

College of Pharmacy & Medical Research Center, Chungbuk National University, Cheongju, Chungbuk 28160, Republic of Korea.

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March 2018

Piperidylmethyloxychalcone improves immune-mediated acute liver failure via inhibiting TAK1 activity.

Authors:

Sun Hong Park Jeong-Ah Kwak Sang-Hun Jung Byeongwoo Ahn Won-Jea Cho Cheong-Yong Yun Chang Seon Na Bang Yeon Hwang Jin Tae Hong Sang-Bae Han Youngsoo Kim

Exp Mol Med 2017 11 17;49(11):e392. Epub 2017 Nov 17.

College of Pharmacy, Chungbuk National University, Cheongju, Korea.

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November 2017

Anti-inflammatory effects of a methanolic extract of Castanea seguinii Dode in LPS-induced RAW264.7 macrophage cells.

Authors:

Yourim Lim Ji-Won Park Ok-Kyoung Kwon Jae-Won Lee Han-Sol Lee Sangwoo Lee Sangho Choi Wanyi Li Hang Jin Sang-Bae Han Kyung-Seop Ahn

Int J Mol Med 2018 Jan 27;41(1):391-398. Epub 2017 Oct 27.

Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheonju-si, Chungcheongbuk-do 28116, Republic of Korea.

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January 2018

Presenilin Mutation Suppresses Lung Tumorigenesis via Inhibition of Peroxiredoxin 6 Activity and Expression.

Authors:

Mi Hee Park Hyung-Mun Yun Chul Ju Hwang Sang Ick Park Sang Bae Han Dae Youn Hwang Do-Young Yoon Sanghyeon Kim Jin Tae Hong

Theranostics 2017 1;7(15):3624-3637. Epub 2017 Sep 1.

College of Pharmacy and Medical Research Center, Chungbuk National University, 12, Gaeshin-dong, Heungduk-gu, Cheongju, Chungbuk 361-763, Republic of Korea.

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June 2018

(E)-2-Methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) Phenol Ameliorates LPS-Mediated Memory Impairment by Inhibition of STAT3 Pathway.

Authors:

Ji Yeon Choi Chul Ju Hwang Do Yeon Lee Sun Mi Gu Hee Pom Lee Dong Young Choi Ki Wan Oh Sang-Bae Han Jin Tae Hong

Neuromolecular Med 2017 Dec 19;19(4):555-570. Epub 2017 Oct 19.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31 Osongsaemgmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju, Chungbuk, 28160, Republic of Korea.

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December 2017

KRICT-9 inhibits neuroinflammation, amyloidogenesis and memory loss in Alzheimer's disease models.

Authors:

Do Yeon Lee Chul Ju Hwang Ji Yeon Choi Mi Hee Park Min Ji Song Ki Wan Oh Sang Bae Han Woo Kyu Park Hee Yeong Cho Sung Yun Cho Hye Byn Park Min Jong Song Jin Tae Hong

Oncotarget 2017 Sep 2;8(40):68654-68667. Epub 2017 Aug 2.

College of Pharmacy and Medical Research Center, Chungbuk National University, Heungduk-gu, Chungbuk 361-951, Republic of Korea.

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September 2017

natural killer cells fail to establish stable contacts with cancer cells and show impaired control of tumor metastasis .

Authors:

Ji Sung Kim Bo Ram Shin Hong Kyung Lee Jae Hee Lee Ki Hun Kim Jeong Eun Choi A Young Ji Jin Tae Hong Youngsoo Kim Sang-Bae Han

Oncoimmunology 2017;6(8):e1338994. Epub 2017 Jul 5.

College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.

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July 2017

Peroxiredoxin 6 overexpression attenuates lipopolysaccharide-induced acute kidney injury.

Authors:

Dong Hun Lee Ju Ho Park Sang Bae Han Do Young Yoon Yu Yeon Jung Jin Tae Hong

Oncotarget 2017 Aug 10;8(31):51096-51107. Epub 2017 Apr 10.

College of Pharmacy and Medical Research Center, Chungbuk National University, Osong-eup, Heungduk-gu, Cheongju, Chungbuk, 361-951, Republic of Korea.

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August 2017

Interleukin-32α Inhibits Endothelial Inflammation, Vascular Smooth Muscle Cell Activation, and Atherosclerosis by Upregulating Timp3 and Reck through suppressing microRNA-205 Biogenesis.

Authors:

Dong Ju Son Yu Yeon Jung Young Sik Seo Heonyong Park Dong Hun Lee Sanghyeon Kim Yoon-Seok Roh Sang Bae Han Do Young Yoon Jin Tae Hong

Theranostics 2017 1;7(8):2186-2203. Epub 2017 Jun 1.

College of Pharmacy & Medical Research Center, Chungbuk National University, Cheongju, Chungbuk 28160, Korea.

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March 2018

Inactivation of human DGAT2 by oxidative stress on cysteine residues.

Authors:

Sunhee Jung Miri Choi Kwangman Choi Eun Bin Kwon Mingu Kang Dong-Eun Kim Hyejeong Jeong Janghwan Kim Jong Heon Kim Mun Ock Kim Sang-Bae Han Sungchan Cho

PLoS One 2017 11;12(7):e0181076. Epub 2017 Jul 11.

Anticancer Agent Research Center, Korea Research Institute of Bioscience & Biotechnology, 30 Yeongudanji-ro, Ochang-eup, Cheongwon-gu, Cheongju-si, Chungcheongbuk-do, South Korea.

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September 2017

Parkin Knockout Inhibits Neuronal Development via Regulation of Proteasomal Degradation of p21.

Authors:

Mi Hee Park Hwa-Jeong Lee Hye Lim Lee Dong Ju Son Jung Hoon Ju Byung Kook Hyun Sung Hee Jung Ju-Kyoung Song Dong Hun Lee Chul Ju Hwang Sang Bae Han Sanghyeon Kim Jin Tae Hong

Theranostics 2017 12;7(7):2033-2045. Epub 2017 May 12.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31, Osongsaengmyeong 1-ro, Osong-eup, Cheongwon-gun, Chungbuk, Republic of Korea, 361-951.

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March 2018

Inhibitory Effect of Carnosol on Phthalic Anhydride-Induced Atopic Dermatitis via Inhibition of STAT3.

Authors:

Do Yeon Lee Chul Ju Hwang Ji Yeon Choi Mi Hee Park Min Ji Song Ki Wan Oh Dong Ju Son Seung Hwa Lee Sang Bae Han Jin Tae Hong

Biomol Ther (Seoul) 2017 Sep;25(5):535-544

College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.

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September 2017

Correction: Tumor growth suppressive effect of IL-4 through p21-mediated activation of STAT6 in IL-4Rα overexpressed melanoma models.

Authors:

Hye Lim Lee Mi Hee Park Ju Kyoung Song Yu Yeon Jung Youngsoo Kim Kyung Bo Kim Dae Yeon Hwang Do Young Yoon Min Jong Song Sang Bae Han Jin Tae Hong

Oncotarget 2017 06;8(25):41778

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June 2017

Activated Natural Killer Cells Mediate the Suppressive Effect of Interleukin-4 on Tumor Development via STAT6 Activation in an Atopic Condition Melanoma Model.

Authors:

Dong Ju Son Yu Yeon Jung Mi Hee Park Hye Lim Lee Min Ji Song Hwan-Soo Yoo Dae Youn Hwang Sang Bae Han Jin Tae Hong

Neoplasia 2017 Jul 3;19(7):537-548. Epub 2017 Jun 3.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31 Osongsaengmyeong 1-ro, Osong-eup, Heungduk-gu, Cheongju, Chungbuk 28160, Republic of Korea. Electronic address:

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July 2017

Inhibitory effect of ethanol extract of Nannochloropsis oceanica on lipopolysaccharide-induced neuroinflammation, oxidative stress, amyloidogenesis and memory impairment.

Authors:

Ji Yeon Choi Chul Ju Hwang Hee Pom Lee Hee Sik Kim Sang-Bae Han Jin Tae Hong

Oncotarget 2017 Jul;8(28):45517-45530

College of Pharmacy and Medical Research Center, Chungbuk National University, Osong-eup, Heungdeok-gu, Cheongju, Chungbuk 28160, Republic of Korea.

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July 2017

Loss of Parkin reduces inflammatory arthritis by inhibiting p53 degradation.

Authors:

Yu Yeon Jung Dong Ju Son Hye Lim Lee Dae Hwan Kim Min Jong Song Young Wan Ham Youngsoo Kim Sang Bae Han Mi Hee Park Jin Tae Hong

Redox Biol 2017 08 5;12:666-673. Epub 2017 Apr 5.

College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong 1-ro 194-31, Osong-eup, Heungduk-gu, Cheongju, Chungbuk 361-951, Republic of Korea. Electronic address:

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August 2017

(E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol suppresses ovarian cancer cell growth via inhibition of ERK and STAT3.

Authors:

Jie Zheng Dong Ju Son Hye Lim Lee Hee Pom Lee Tae Hoon Kim Jung Heun Joo Young Wan Ham Wun Jae Kim Jae Kyung Jung Sang-Bae Han Jin Tae Hong

Mol Carcinog 2017 09 30;56(9):2003-2013. Epub 2017 Mar 30.

College of Pharmacy & Medical Research Center, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.

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September 2017

Novel N-hydroxybenzamides incorporating 2-oxoindoline with unexpected potent histone deacetylase inhibitory effects and antitumor cytotoxicity.

Authors:

Tran-Thi-Lan Huong Do-Thi-Mai Dung Nguyen-Van Huan Le-Van Cuong Pham-The Hai Le-Thi-Thu Huong Jisung Kim Yong-Guk Kim Sang-Bae Han Nguyen-Hai Nam

Bioorg Chem 2017 04 8;71:160-169. Epub 2017 Feb 8.

Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Viet Nam. Electronic address:

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April 2017

Caffeic Acid Cyclohexylamide Rescues Lethal Inflammation in Septic Mice through Inhibition of IκB Kinase in Innate Immune Process.

Authors:

Jun Hyeon Choi Sun Hong Park Jae-Kyung Jung Won-Jea Cho Byeongwoo Ahn Cheong-Yong Yun Yong Pyo Choi Jong Hun Yeo Heesoon Lee Jin Tae Hong Sang-Bae Han Youngsoo Kim

Sci Rep 2017 02 1;7:41180. Epub 2017 Feb 1.

College of Pharmacy, Chungbuk National University, Cheongju 362-763, Korea.

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February 2017

Inhibitory effect of punicalagin on lipopolysaccharide-induced neuroinflammation, oxidative stress and memory impairment via inhibition of nuclear factor-kappaB.

Authors:

Young Eun Kim Chul Ju Hwang Hee Pom Lee Chun Sik Kim Dong Ju Son Young Wan Ham Mats Hellström Sang-Bae Han Hee Sik Kim Eun Kyung Park Jin Tae Hong

Neuropharmacology 2017 05 26;117:21-32. Epub 2017 Jan 26.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31, Osongsangmyeong1-ro, Heungdeok-gu, Cheongju, Chungbuk 28160, Republic of Korea. Electronic address:

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May 2017

CCL2 deficient mesenchymal stem cells fail to establish long-lasting contact with T cells and no longer ameliorate lupus symptoms.

Authors:

Hong Kyung Lee Hyung Sook Kim Ji Sung Kim Yong Guk Kim Ki Hwan Park Jae Hee Lee Ki Hun Kim In Young Chang Sang-Cheol Bae Youngsoo Kim Jin Tae Hong John H Kehrl Sang-Bae Han

Sci Rep 2017 01 24;7:41258. Epub 2017 Jan 24.

College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk 28160, Republic of Korea.

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January 2017

Parkin deficiency exacerbate ethanol-induced dopaminergic neurodegeneration by P38 pathway dependent inhibition of autophagy and mitochondrial function.

Authors:

Chul Ju Hwang Young Eun Kim Dong Ju Son Mi Hee Park Dong-Young Choi Pil-Hoon Park Mats Hellström Sang-Bae Han Ki-Wan Oh Eun Kyung Park Jin Tae Hong

Redox Biol 2017 04 8;11:456-468. Epub 2016 Dec 8.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31, Osongsangmyeong1-ro, Heungdeok-gu, Cheongju, Chungbuk 361-951, Republic of Korea. Electronic address:

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April 2017

Piperlongumine attenuates experimental autoimmune encephalomyelitis through inhibition of NF-kappaB activity.

Authors:

Sun Mi Gu Jaesuk Yun Dong Ju Son Hoi Yeong Kim Kyung Tak Nam Hae Deun Kim Min Gi Choi Jeong Soon Choi Young Min Kim Sang-Bae Han Jin Tae Hong

Free Radic Biol Med 2017 02 21;103:133-145. Epub 2016 Dec 21.

College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31, Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju-si, Chungcheongbuk-do 28160, Republic of Korea. Electronic address:

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February 2017

Cytokine-induced killer cells hunt individual cancer cells in droves in a mouse model.

Authors:

Ji Sung Kim Yong Guk Kim Hong Kyung Lee Eun Jae Park Boyeong Kim Jong Soon Kang Heesoon Lee Youngsoo Kim Jin Tae Hong Sang-Bae Han

Cancer Immunol Immunother 2017 Feb 25;66(2):193-202. Epub 2016 Nov 25.

College of Pharmacy, Chungbuk National University, 194-31 Osongsaengmyung-1, Heungdeok, Cheongju, Chungbuk, 28160, Republic of Korea.

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February 2017

Novel synthetic (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol inhibits arthritis by targeting signal transducer and activator of transcription 3.

Authors:

Dong Ju Son Dae Hwan Kim Seong-Su Nah Mi Hee Park Hee Pom Lee Sang Bae Han Udumula Venkatareddy Benjamin Gann Kevin Rodriguez Scott R Burt Young Wan Ham Yu Yeon Jung Jin Tae Hong

Sci Rep 2016 11 15;6:36852. Epub 2016 Nov 15.

College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju, Chungbuk 28160, Korea.

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November 2016

MIR144* inhibits antimicrobial responses against Mycobacterium tuberculosis in human monocytes and macrophages by targeting the autophagy protein DRAM2.

Authors:

Jin Kyung Kim Hye-Mi Lee Ki-Sun Park Dong-Min Shin Tae Sung Kim Yi Sak Kim Hyun-Woo Suh Soo Yeon Kim In Soo Kim Jin-Man Kim Ji-Woong Son Kyung Mok Sohn Sung Soo Jung Chaeuk Chung Sang-Bae Han Chul-Su Yang Eun-Kyeong Jo

Autophagy 2017 Feb 20;13(2):423-441. Epub 2016 Oct 20.

a Department of Microbiology , Chungnam National University School of Medicine , Daejeon , Korea.

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February 2017

miR-6734 Up-Regulates p21 Gene Expression and Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Cells.

Authors:

Moo Rim Kang Ki Hwan Park Jeong-Ook Yang Chang Woo Lee Soo Jin Oh Jieun Yun Myeong Youl Lee Sang-Bae Han Jong Soon Kang

PLoS One 2016 10;11(8):e0160961. Epub 2016 Aug 10.

Bio-Evaluation Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, Republic of Korea.

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August 2017

Curdlan activates dendritic cells through dectin-1 and toll-like receptor 4 signaling.

Authors:

Hyung Sook Kim Ki Hwan Park Hong Kyung Lee Ji Sung Kim Yong Guk Kim Jae Hee Lee Ki Hun Kim Jieun Yun Bang Yeon Hwang Jin Tae Hong Youngsoo Kim Sang-Bae Han

Int Immunopharmacol 2016 Oct 21;39:71-78. Epub 2016 Jul 21.

College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk 28644, Republic of Korea. Electronic address:

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October 2016

Inhibitory effect of thiacremonone on MPTP-induced dopaminergic neurodegeneration through inhibition of p38 activation.

Authors:

Chul Ju Hwang Hee Pom Lee Dong-Young Choi Heon Sang Jeong Tae Hoon Kim Tae Hyung Lee Young Min Kim Dae Bong Moon Sung Sik Park Sun Young Kim Ki-Wan Oh Dae Yeon Hwang Sang-Bae Han Hwa-Jeong Lee Jin Tae Hong

Oncotarget 2016 Jul;7(30):46943-46958

College of Pharmacy and Medical Research Center, Chungbuk National University, Osongsaengmyeong, Osong-eup, Heungduk-gu, Cheongju, Chungbuk, Republic of Korea.

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July 2016

Antiviral activity of micafungin against enterovirus 71.

Authors:

Chonsaeng Kim Hyunju Kang Dong-Eun Kim Jae-Hyoung Song Miri Choi Mingu Kang Kyungjin Lee Hae Soo Kim Jin Soo Shin Hyejeong Jeong Sunhee Jung Sang-Bae Han Jong Heon Kim Hyun-Jeong Ko Chong-Kyo Lee Meehyein Kim Sungchan Cho

Virol J 2016 Jun 13;13:99. Epub 2016 Jun 13.

Anticancer Agent Research Center, Korea Research Institute of Bioscience & Biotechnology, 30 Yeongudanji-ro, Ochang-eup, Cheongwon-gu, Cheongju-si, Chungcheongbuk-do, 28116, South Korea.

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June 2016