Publications by authors named "Sandrine Faivre"

100Publications

Selective Oral MEK1/2 Inhibitor Pimasertib in Metastatic Melanoma: Antitumor Activity in a Phase I, Dose-Escalation Trial.

Authors:
Céleste Lebbé Antoine Italiano Nadine Houédé Ahmad Awada Philippe Aftimos Thierry Lesimple Monica Dinulescu Jan H M Schellens Suzanne Leijen Sylvie Rottey Vibeke Kruse Richard Kefford Eric Raymond Sandrine Faivre Celine Pages Carlos Gomez-Roca Armin Schueler Samantha Goodstal Giorgio Massimini Jean-Pierre Delord

Target Oncol 2021 Jan;16(1):47-57

Clinical Research Unit, Institut Universitaire du Cancer, Oncopole, Toulouse, France.

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January 2021

Selective Oral MEK1/2 Inhibitor Pimasertib: A Phase I Trial in Patients with Advanced Solid Tumors.

Authors:
Jean-Pierre Delord Antoine Italiano Ahmad Awada Philippe Aftimos Nadine Houédé Céleste Lebbé Celine Pages Thierry Lesimple Monica Dinulescu Jan H M Schellens Suzanne Leijen Sylvie Rottey Vibeke Kruse Richard Kefford Sandrine Faivre Carlos Gomez-Roca Armin Scheuler Giorgio Massimini Eric Raymond

Target Oncol 2021 Jan;16(1):37-46

Paris Diderot University Hospital, Clichy, France.

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January 2021

Impact of the COVID-19 Outbreak on the Management of Patients with Cancer.

Authors:
Eric Raymond Catherine Thieblemont Severine Alran Sandrine Faivre

Target Oncol 2020 06;15(3):249-259

Medical Oncology, Saint-Louis Hospital, AP-HP, Paris 7 University, Paris, France.

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June 2020

Biomarkers and overall survival in patients with advanced hepatocellular carcinoma treated with TGF-βRI inhibitor galunisertib.

Authors:
Gianluigi Giannelli Armando Santoro Robin K Kelley Ed Gane Valerie Paradis Ann Cleverly Claire Smith Shawn T Estrem Michael Man Shuaicheng Wang Michael M Lahn Eric Raymond Karim A Benhadji Sandrine Faivre

PLoS One 2020 25;15(3):e0222259. Epub 2020 Mar 25.

Paris Saint-Joseph Hospital Center, Paris, France.

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May 2020

Multimodal strategy for the management of sphenoid osteoradionecrosis: Preliminary results.

Authors:
Hannah Daoudi Marc A Labeyrie Sophie Guillerm Sylvie Delanian Jean-Pierre Guichard Clément Jourdaine Sandrine Faivre Helene Gauthier François-Régis Ferrand Benjamin Verillaud Philippe Herman

Laryngoscope Investig Otolaryngol 2020 Feb 22;5(1):19-23. Epub 2020 Jan 22.

Department of Otorhinolaryngology Assistance Publique - Hôpitaux de Paris, Hôpital Lariboisière Paris France.

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February 2020

Molecular therapies for HCC: Looking outside the box.

Authors:
Sandrine Faivre Lorenza Rimassa Richard S Finn

J Hepatol 2020 02;72(2):342-352

Department of Medicine, Division of Hematology/Oncology, Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

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February 2020

Astonishing Evolution in Oropharyngeal Cancer with Immunotherapy: A Case Report.

Authors:
Alexandre Rossillon Jonathan Benhamou Laurent S Baccar Muriel Hourseau Barry Beatrix Sandrine Faivre Stephane Culine Philippe Maingon Michele Lamuraglia

Cancer Invest 2019 16;37(10):531-534. Epub 2019 Oct 16.

Oncology Unit, Hopital Beaujon, Clichy, France.

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December 2019

First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant FGF19 Signaling as a Driver Event in Hepatocellular Carcinoma.

Authors:
Richard D Kim Debashis Sarker Tim Meyer Thomas Yau Teresa Macarulla Joong-Won Park Su Pin Choo Antoine Hollebecque Max W Sung Ho-Yeong Lim Vincenzo Mazzaferro Joerg Trojan Andrew X Zhu Jung-Hwan Yoon Sunil Sharma Zhong-Zhe Lin Stephen L Chan Sandrine Faivre Lynn G Feun Chia-Jui Yen Jean-Francois Dufour Daniel H Palmer Josep M Llovet Melissa Manoogian Meera Tugnait Nicolas Stransky Margit Hagel Nancy E Kohl Christoph Lengauer Cori Ann Sherwin Oleg Schmidt-Kittler Klaus P Hoeflich Hongliang Shi Beni B Wolf Yoon-Koo Kang

Cancer Discov 2019 12 1;9(12):1696-1707. Epub 2019 Oct 1.

Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.

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December 2019

Clinical Impact of Genomic Diversity From Early to Advanced Hepatocellular Carcinoma.

Authors:
Jean-Charles Nault Yoann Martin Stefano Caruso Théo Z Hirsch Quentin Bayard Julien Calderaro Cecile Charpy Christiane Copie-Bergman Marianne Ziol Paulette Bioulac-Sage Gabrielle Couchy Jean-Frédéric Blanc Pierre Nahon Giuliana Amaddeo Nathalie Ganne-Carrie Guillaume Morcrette Laurence Chiche Christophe Duvoux Sandrine Faivre Alexis Laurent Sandrine Imbeaud Sandra Rebouissou Josep M Llovet Olivier Seror Eric Letouzé Jessica Zucman-Rossi

Hepatology 2020 01 12;71(1):164-182. Epub 2019 Aug 12.

Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, USPC, Université Paris Descartes, Université Paris Diderot, Université Paris 13, Functional Genomics of Solid Tumors Laboratory, Paris, France.

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January 2020

Novel transforming growth factor beta receptor I kinase inhibitor galunisertib (LY2157299) in advanced hepatocellular carcinoma.

Authors:
Sandrine Faivre Armando Santoro Robin K Kelley Ed Gane Charlotte E Costentin Ivelina Gueorguieva Claire Smith Ann Cleverly Michael M Lahn Eric Raymond Karim A Benhadji Gianluigi Giannelli

Liver Int 2019 08 3;39(8):1468-1477. Epub 2019 Jun 3.

National Institute of Gastroenterology, Research Instituts "S. De Bellis" Research Hospital, Castellana Grotte, Bari, Italy.

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August 2019

Comparative analysis of the phase III clinical trials of anti-PD1 monotherapy in head and neck squamous cell carcinoma patients (CheckMate 141 and KEYNOTE 040).

Authors:
Sara I Pai Sandrine Faivre Lisa Licitra Jean-Pascal Machiels Jan B Vermorken Paolo Bruzzi Viktor Gruenwald Raul E Giglio C René Leemans Tanguy Y Seiwert Denis Soulieres

J Immunother Cancer 2019 04 3;7(1):96. Epub 2019 Apr 3.

Département Hématologie-oncologie, Centre hospitalier de l'Université de Montréal, Montréal, Canada.

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April 2019

Macrophages in the microenvironment of head and neck cancer: potential targets for cancer therapy.

Authors:
Diane Evrard Petr Szturz Annemilaï Tijeras-Raballand Lucile Astorgues-Xerri Chloé Abitbol Valérie Paradis Eric Raymond Sébastien Albert Béatrix Barry Sandrine Faivre

Oral Oncol 2019 01 20;88:29-38. Epub 2018 Nov 20.

Medical Oncology Department, Hôpitaux Universitaires Paris Nord Val de Seine (HUPVNS) & Université Paris 7, Paris, France. Electronic address:

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January 2019

New trials and results in systemic treatment of HCC.

Authors:
María Reig Leonardo Gomes da Fonseca Sandrine Faivre

J Hepatol 2018 08 11;69(2):525-533. Epub 2018 Apr 11.

Medical Oncology, Hôpitaux Universitaires Paris Nord Val de Seine (HUPVNS), INSERMU1149 & Université Paris 7, Paris, France. Electronic address:

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August 2018

Clinical and Biomarker Evaluations of Sunitinib in Patients with Grade 3 Digestive Neuroendocrine Neoplasms.

Authors:
Anna Pellat Chantal Dreyer Camille Couffignal Thomas Walter Catherine Lombard-Bohas Patricia Niccoli Jean François Seitz Olivia Hentic Thierry André Romain Coriat Sandrine Faivre Magaly Zappa Philippe Ruszniewski Nicolas Pote Anne Couvelard Eric Raymond

Neuroendocrinology 2018 8;107(1):24-31. Epub 2018 Mar 8.

Medical Oncology, Hôpital Saint Joseph, AP-HP, Paris, France.

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January 2019

Molecular Alterations and Buparlisib Efficacy in Patients with Squamous Cell Carcinoma of the Head and Neck: Biomarker Analysis from BERIL-1.

Authors:
Denis Soulières Lisa Licitra Ricard Mesía Éva Remenár Shau-Hsuan Li Andrey Karpenko Marie Chol Ying A Wang Nadia Solovieff Laurence Bourdeau Dalila Sellami Sandrine Faivre

Clin Cancer Res 2018 06 28;24(11):2505-2516. Epub 2018 Feb 28.

Hôpitaux Universitaires Paris Nord Val de Seine, Paris, France.

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June 2018

Determination of an optimal response cut-off able to predict progression-free survival in patients with well-differentiated advanced pancreatic neuroendocrine tumours treated with sunitinib: an alternative to the current RECIST-defined response.

Authors:
Angela Lamarca Jorge Barriuso Matthew Kulke Ivan Borbath Heinz-Josef Lenz Jean Luc Raoul Neal J Meropol Catherine Lombard-Bohas James Posey Sandrine Faivre Eric Raymond Juan W Valle

Br J Cancer 2018 01 21;118(2):181-188. Epub 2017 Nov 21.

Department of Medical Oncology, The Christie NHS Foundation Trust (ENETS Centre of Excellence), Manchester M20 4BX, UK.

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January 2018

Prognostic value of c-MET in head and neck cancer: A systematic review and meta-analysis of aggregate data.

Authors:
Petr Szturz Marie Budíková Jan B Vermorken Ivana Horová Břetislav Gál Eric Raymond Armand de Gramont Sandrine Faivre

Oral Oncol 2017 11 27;74:68-76. Epub 2017 Sep 27.

Department of Oncology, Bichat-Beaujon University Hospital, Paris, France.

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November 2017

Recent developments of c-Met as a therapeutic target in hepatocellular carcinoma.

Authors:
Mohamed Bouattour Eric Raymond Shukui Qin Ann-Lii Cheng Uz Stammberger Giuseppe Locatelli Sandrine Faivre

Hepatology 2018 03 1;67(3):1132-1149. Epub 2018 Feb 1.

Medical Oncology Department, Beaujon University Hospital, Clichy, France.

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March 2018

A Phase II Multicentre, Open-Label, Proof-of-Concept Study of Tasquinimod in Hepatocellular, Ovarian, Renal Cell, and Gastric Cancers.

Authors:
Bernard Escudier Sandrine Faivre Eric Van Cutsem Nathalie Germann Jean-Christophe Pouget Ruth Plummer Ignace Vergote Fiona Thistlethwaite Georg A Bjarnason Robert Jones Helen Mackay Julien Edeline Laetitia Fartoux Hal Hirte Amit Oza

Target Oncol 2017 10;12(5):655-661

Beatson West of Scotland Cancer Centre, University of Glasgow, Glasgow, UK.

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October 2017

Novel TGF- inhibitors ready for prime time in onco-immunology.

Authors:
Armand de Gramont Sandrine Faivre Eric Raymond

Oncoimmunology 2017;6(1):e1257453. Epub 2016 Dec 7.

Medical Oncology, Groupe Hospitalier Paris Saint-Joseph , Paris, France.

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December 2016

Buparlisib and paclitaxel in patients with platinum-pretreated recurrent or metastatic squamous cell carcinoma of the head and neck (BERIL-1): a randomised, double-blind, placebo-controlled phase 2 trial.

Authors:
Denis Soulières Sandrine Faivre Ricard Mesía Éva Remenár Shau-Hsuan Li Andrey Karpenko Arunee Dechaphunkul Sebastian Ochsenreither Laura Anna Kiss Jin-Ching Lin Raj Nagarkar László Tamás Sung-Bae Kim Jozsef Erfán Anna Alyasova Stefan Kasper Carlo Barone Sabine Turri Arunava Chakravartty Marie Chol Paola Aimone Samit Hirawat Lisa Licitra

Lancet Oncol 2017 03 26;18(3):323-335. Epub 2017 Jan 26.

Head and Neck Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; University of Milan, Milan, Italy. Electronic address:

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March 2017

Pharmacokinetics and safety of DTS-108, a human oligopeptide bound to SN-38 with an esterase-sensitive cross-linker in patients with advanced malignancies: a Phase I study.

Authors:
Romain Coriat Sandrine J Faivre Olivier Mir Chantal Dreyer Stanislas Ropert Mohammed Bouattour Robert Desjardins François Goldwasser Eric Raymond

Int J Nanomedicine 2016;11:6207-6216. Epub 2016 Nov 21.

Groupe Hospitalier Paris Saint-Joseph, Paris, France.

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February 2017

Adjuvant therapies in advanced hepatocellular carcinoma: moving forward from the STORM.

Authors:
Mohamed Bouattour Olivier Soubrane Armand de Gramont Sandrine Faivre

Trials 2016 11 25;17(1):563. Epub 2016 Nov 25.

Medical Oncology Department, Beaujon University Hospital, Clichy, France.

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November 2016

Strong antineoplastic effects of metformin in preclinical models of liver carcinogenesis.

Authors:
François Cauchy Mouniya Mebarki Benjamin Leporq Samira Laouirem Miguel Albuquerque Simon Lambert Pierre Bourgoin Olivier Soubrane Bernard E Van Beers Sandrine Faivre Pierre Bedossa Valérie Paradis

Clin Sci (Lond) 2017 01 1;131(1):27-36. Epub 2016 Nov 1.

INSERM UMR 1149, Inflammation Research Center, Paris-Diderot University, Paris, France

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January 2017

Everolimus affects vasculogenic mimicry in renal carcinoma resistant to sunitinib.

Authors:
Maria Serova Annemilaï Tijeras-Raballand Celia Dos Santos Matthieu Martinet Cindy Neuzillet Alfred Lopez Dianne C Mitchell Brad A Bryan Guillaume Gapihan Anne Janin Guilhem Bousquet Maria Eugenia Riveiro Ivan Bieche Sandrine Faivre Eric Raymond Armand de Gramont

Oncotarget 2016 Jun;7(25):38467-86

AAREC Filia Research, Boulogne-Billancourt, France.

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June 2016

Efficacy of a sequential treatment strategy with GEMOX-based followed by FOLFIRI-based chemotherapy in advanced biliary tract cancers.

Authors:
Sihem Sebbagh Julia Roux Chantal Dreyer Cindy Neuzillet Armand de Gramont Cecilia Orbegoso Olivia Hentic Pascal Hammel Aimery de Gramont Eric Raymond Thierry André Benoist Chibaudel Sandrine Faivre

Acta Oncol 2016 Sep - Oct;55(9-10):1168-1174. Epub 2016 Jun 22.

a Department of Medical Oncology , Beaujon University Hospital, Assistance Publique-Hôpitaux De Paris (AP-HP) , Clichy , France.

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January 2018

c-MET-mediated resistance to EGFR inhibitors in head and neck cancer: How to move from bench to bedside.

Authors:
Petr Szturz Eric Raymond Sandrine Faivre

Oral Oncol 2016 08 11;59:e12-e14. Epub 2016 Jun 11.

Department of Oncology, Bichat-Beaujon University Hospital, Paris, France.

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August 2016

Learning from 7 Years of Experience with Sorafenib in Advanced HCC: Sorafenib Better than Sorafenib?

Authors:
Sandrine Faivre Armand de Gramont Eric Raymond

Target Oncol 2016 08;11(4):565-7

Medical Oncology, Hôpitaux Universitaires Paris Nord Val de Seine (HUPVNS), Université Paris 7, 75010, Paris, France.

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August 2016

Phase I dose escalation and pharmacokinetic evaluation of two different schedules of LY2334737, an oral gemcitabine prodrug, in patients with advanced solid tumors.

Authors:
Sandrine J Faivre Anthony J Olszanski Karin Weigang-Köhler Hanno Riess Roger B Cohen Xuejing Wang Scott P Myrand Enaksha R Wickremsinhe Candice L Horn Haojun Ouyang Sophie Callies Karim A Benhadji Eric Raymond

Invest New Drugs 2015 Dec 16;33(6):1206-16. Epub 2015 Sep 16.

Department of Medical Oncology, Beaujon University Hospital, Clichy, France.

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December 2015

Targeting cancer cell metabolism in pancreatic adenocarcinoma.

Authors:
Romain Cohen Cindy Neuzillet Annemilaï Tijeras-Raballand Sandrine Faivre Armand de Gramont Eric Raymond

Oncotarget 2015 Jul;6(19):16832-47

Medical Oncology, Department of Oncology, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.

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July 2015

Effects of TGF-beta signalling inhibition with galunisertib (LY2157299) in hepatocellular carcinoma models and in ex vivo whole tumor tissue samples from patients.

Authors:
Maria Serova Annemilaï Tijeras-Raballand Célia Dos Santos Miguel Albuquerque Valerie Paradis Cindy Neuzillet Karim A Benhadji Eric Raymond Sandrine Faivre Armand de Gramont

Oncotarget 2015 Aug;6(25):21614-27

AAREC Filia Research, Boulogne-Billancourt, France.

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August 2015

Disease control with sunitinib in advanced intrahepatic cholangiocarcinoma resistant to gemcitabine-oxaliplatin chemotherapy.

Authors:
Chantal Dreyer Marie-Paule Sablin Mohamed Bouattour Cindy Neuzillet Maxime Ronot Safi Dokmak Jacques Belghiti Nathalie Guedj Valérie Paradis Eric Raymond Sandrine Faivre

World J Hepatol 2015 Apr;7(6):910-5

Chantal Dreyer, Marie-Paule Sablin, Mohamed Bouattour, Cindy Neuzillet, Eric Raymond, Sandrine Faivre, Department of Medical Oncology, Beaujon University Hospital (AP-HP - PRES Paris 7 Diderot), 92110 Clichy, France.

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April 2015

Targeting the TGFβ pathway for cancer therapy.

Authors:
Cindy Neuzillet Annemilaï Tijeras-Raballand Romain Cohen Jérôme Cros Sandrine Faivre Eric Raymond Armand de Gramont

Pharmacol Ther 2015 Mar 6;147:22-31. Epub 2014 Nov 6.

New Drug Evaluation Laboratory, Centre of Experimental Therapeutics and Medical Oncology, Department of Oncology, Centre Hospitalier Universitaire Vaudois (CHUV) Lausanne, Switzerland. Electronic address:

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March 2015

Practical management of sunitinib toxicities in the treatment of pancreatic neuroendocrine tumors.

Authors:
Juan W Valle Sandrine Faivre Richard A Hubner Enrique Grande Eric Raymond

Cancer Treat Rev 2014 Dec 16;40(10):1230-8. Epub 2014 Sep 16.

Medical Oncology, Beaujon University Hospital (AP-HP) Paris 7 Diderot, Clichy, France.

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December 2014

Insights on the CXCL12-CXCR4 axis in hepatocellular carcinoma carcinogenesis.

Authors:
Ismael Ghanem Maria E Riveiro Valerie Paradis Sandrine Faivre Paula M Vázquez de Parga Eric Raymond

Am J Transl Res 2014 18;6(4):340-52. Epub 2014 Jul 18.

INSERM U728 and Medical Oncology Departments, Beaujon University Hospital (AP-HP - PRES Paris 7 Diderot) 100 bd du Général Leclerc, 92110 Clichy, France.

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July 2014

OTX008, a selective small-molecule inhibitor of galectin-1, downregulates cancer cell proliferation, invasion and tumour angiogenesis.

Authors:
Lucile Astorgues-Xerri Maria E Riveiro Annemilaï Tijeras-Raballand Maria Serova Gabriel A Rabinovich Ivan Bieche Michel Vidaud Armand de Gramont Mathieu Martinet Esteban Cvitkovic Sandrine Faivre Eric Raymond

Eur J Cancer 2014 Sep 16;50(14):2463-77. Epub 2014 Jul 16.

INSERM U728 and Medical Oncology Department, Beaujon University Hospital (AP-HP - PRES Paris 7 Diderot), 100 bd du Général Leclerc, 92110 Clichy, France. Electronic address:

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September 2014

Gemcitabine and oxaliplatin with or without cetuximab in advanced biliary-tract cancer (BINGO): a randomised, open-label, non-comparative phase 2 trial.

Authors:
David Malka Pascale Cervera Stéphanie Foulon Tanja Trarbach Christelle de la Fouchardière Eveline Boucher Laetitia Fartoux Sandrine Faivre Jean-Frédéric Blanc Frédéric Viret Eric Assenat Thomas Seufferlein Thomas Herrmann Julien Grenier Pascal Hammel Matthias Dollinger Thierry André Philipp Hahn Volker Heinemann Vanessa Rousseau Michel Ducreux Jean-Pierre Pignon Dominique Wendum Olivier Rosmorduc Tim F Greten

Lancet Oncol 2014 Jul 19;15(8):819-28. Epub 2014 May 19.

Hannover Medical School, Hannover, Germany.

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July 2014

Benzofuran derivatives as anticancer inhibitors of mTOR signaling.

Authors:
Christophe Salomé Nigel Ribeiro Thierry Chavagnan Frédéric Thuaud Maria Serova Armand de Gramont Sandrine Faivre Eric Raymond Laurent Désaubry

Eur J Med Chem 2014 Jun 5;81:181-91. Epub 2014 May 5.

Therapeutic Innovation Laboratory, UMR7200, CNRS/Université de Strasbourg, Illkirch, France. Electronic address:

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June 2014

Cancer wars: natural products strike back.

Authors:
Christine Basmadjian Qian Zhao Embarek Bentouhami Amel Djehal Canan G Nebigil Roger A Johnson Maria Serova Armand de Gramont Sandrine Faivre Eric Raymond Laurent G Désaubry

Front Chem 2014 1;2:20. Epub 2014 May 1.

Therapeutic Innovation Laboratory, UMR7200, CNRS/University of Strasbourg Illkirch, France.

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June 2014

Gemcitabine and oxaliplatin chemotherapy for advanced hepatocellular carcinoma after failure of anti-angiogenic therapies.

Authors:
Anna Patrikidou Isabelle Sinapi Hélène Regnault Florence Fayard Mohamed Bouattour Laetitia Fartoux Sandrine Faivre David Malka Michel Ducreux Valerie Boige

Invest New Drugs 2014 Oct 22;32(5):1028-35. Epub 2014 Apr 22.

Department of Oncologic Medicine, Gustave-Roussy, Villejuif, France.

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October 2014

Colorectal liver metastases growth in the embolized and non-embolized liver after portal vein embolization: influence of initial response to induction chemotherapy.

Authors:
Romain Pommier Maxime Ronot François Cauchy Sébastien Gaujoux David Fuks Sandrine Faivre Jacques Belghiti Valérie Vilgrain

Ann Surg Oncol 2014 Sep 18;21(9):3077-83. Epub 2014 Apr 18.

Department of Radiology, Beaujon Hospital (AP-HP), Beaujon University Hospitals Paris Nord Val de Seine, Clichy, Hauts-de-Seine, France.

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September 2014

Alternative Response Criteria (Choi, European association for the study of the liver, and modified Response Evaluation Criteria in Solid Tumors [RECIST]) Versus RECIST 1.1 in patients with advanced hepatocellular carcinoma treated with sorafenib.

Authors:
Maxime Ronot Mohamed Bouattour Johanna Wassermann Onorina Bruno Chantal Dreyer Béatrice Larroque Laurent Castera Valérie Vilgrain Jacques Belghiti Eric Raymond Sandrine Faivre

Oncologist 2014 Apr 20;19(4):394-402. Epub 2014 Mar 20.

Departments of Radiology, Hepatology, Medical Oncology, Biostatistics, and Hepatobiliary and Pancreatic Surgery, Beaujon University Hospital, Assistance Publique Hopitaux de Paris, Clichy, France.

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April 2014

Methods for adjusting for bias due to crossover in oncology trials.

Authors:
K Jack Ishak Irina Proskorovsky Beata Korytowsky Rickard Sandin Sandrine Faivre Juan Valle

Pharmacoeconomics 2014 Jun;32(6):533-46

Evidera, 7575 Trans-Canada Highway, Suite 500, St-Laurent, QC, H4T 1V6, Canada,

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June 2014

Benzofuran derivatives as a novel class of inhibitors of mTOR signaling.

Authors:
Christophe Salomé Vanessa Narbonne Nigel Ribeiro Frédéric Thuaud Maria Serova Armand de Gramont Sandrine Faivre Eric Raymond Laurent Désaubry

Eur J Med Chem 2014 Mar 2;74:41-9. Epub 2014 Jan 2.

Therapeutic Innovation Laboratory, UMR7200, CNRS/Université de Strasbourg, Illkirch, France. Electronic address:

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March 2014

Transcriptional profiling of pure fibrolamellar hepatocellular carcinoma reveals an endocrine signature.

Authors:
Gabriel G Malouf Sylvie Job Valérie Paradis Monique Fabre Laurence Brugières Pierre Saintigny Laure Vescovo Jacques Belghiti Sophie Branchereau Sandrine Faivre Aurélien de Reyniès Eric Raymond

Hepatology 2014 Jun 30;59(6):2228-37. Epub 2014 Apr 30.

Department of Medical Oncology, Beaujon University Hospital and INSERM U728, Clichy, France.

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June 2014

Phase I study of elisidepsin (Irvalec®) in combination with carboplatin or gemcitabine in patients with advanced malignancies.

Authors:
Francois Goldwasser Sandrine Faivre Jerome Alexandre Cinthya Coronado Eva M Fernández-García Carmen M Kahatt Pilar García Paramio Jorge Luis Iglesias Dios Bernardo Miguel-Lillo Eric Raymond

Invest New Drugs 2014 Jun 7;32(3):500-9. Epub 2014 Jan 7.

AP-HP, Faculté de Medicine Paris Descartes, Hôpital Cochin, Paris, France.

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June 2014

Perspectives of TGF-β inhibition in pancreatic and hepatocellular carcinomas.

Authors:
Cindy Neuzillet Armand de Gramont Annemilaï Tijeras-Raballand Louis de Mestier Jérome Cros Sandrine Faivre Eric Raymond

Oncotarget 2014 Jan;5(1):78-94

INSERM U728 and U773 and Department of Medical Oncology, Beaujon University Hospital (AP-HP - PRES Paris 7 Diderot), 100 boulevard du Général Leclerc, Clichy, France.

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January 2014

MEK in cancer and cancer therapy.

Authors:
Cindy Neuzillet Annemilaï Tijeras-Raballand Louis de Mestier Jérôme Cros Sandrine Faivre Eric Raymond

Pharmacol Ther 2014 Feb 9;141(2):160-71. Epub 2013 Oct 9.

INSERM U728 and Department of Medical Oncology, Beaujon University Hospital, AP-HP-PRES, Paris 7 Diderot, 100 boulevard du Général Leclerc, 92110 Clichy, France. Electronic address:

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February 2014

Differential regulation of sunitinib targets predicts its tumor-type-specific effect on endothelial and/or tumor cell apoptosis.

Authors:
Guilhem Bousquet Mariana Varna Irmine Ferreira Li Wang Pierre Mongiat-Artus Christophe Leboeuf Cédric de Bazelaire Sandrine Faivre Philippe Bertheau Eric Raymond Stéphane Germain Anne Janin

Cancer Chemother Pharmacol 2013 Dec 24;72(6):1183-93. Epub 2013 Sep 24.

Sorbonne Paris Cité, Laboratoire de Pathologie, UMR-S728, Université Paris Diderot, 75010, Paris, France.

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December 2013

Unraveling galectin-1 as a novel therapeutic target for cancer.

Authors:
Lucile Astorgues-Xerri Maria E Riveiro Annemilaï Tijeras-Raballand Maria Serova Cindy Neuzillet Sébastien Albert Eric Raymond Sandrine Faivre

Cancer Treat Rev 2014 Mar 1;40(2):307-19. Epub 2013 Aug 1.

Oncology Therapeutic Development, 100 rue Martre, 92110 Clichy, France. Electronic address:

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March 2014

Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): an open-label phase 3 randomised trial.

Authors:
Jan B Vermorken Jan Stöhlmacher-Williams Irina Davidenko Lisa Licitra Eric Winquist Cristian Villanueva Paolo Foa Sylvie Rottey Krzysztof Skladowski Makoto Tahara Vasant R Pai Sandrine Faivre Cesar R Blajman Arlene A Forastiere Brian N Stein Kelly S Oliner Zhiying Pan Bruce A Bach

Lancet Oncol 2013 Jul 6;14(8):697-710. Epub 2013 Jun 6.

Department of Medical Oncology, Antwerp University Hospital, Edegem, Belgium.

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July 2013

Safety of liver resection for hepatocellular carcinoma after sorafenib therapy: a multicenter case-matched study.

Authors:
Louise Barbier David Fuks Patrick Pessaux Fabrice Muscari Yves-Patrice Le Treut Sandrine Faivre Jacques Belghiti

Ann Surg Oncol 2013 Oct 29;20(11):3603-9. Epub 2013 May 29.

Department of HPB Surgery, Beaujon Hospital, Clichy, France.

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October 2013

Stromal expression of SPARC in pancreatic adenocarcinoma.

Authors:
Cindy Neuzillet Annemilaï Tijeras-Raballand Jérôme Cros Sandrine Faivre Pascal Hammel Eric Raymond

Cancer Metastasis Rev 2013 Dec;32(3-4):585-602

Department of Medical Oncology (INSERM U728-PRES Paris 7 Diderot), Beaujon University Hospital, Assistance Publique-Hôpitaux de Paris, 100 boulevard du Général Leclerc, 92110, Clichy-La-Garenne, France.

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December 2013

Predictive factors of sensitivity to elisidepsin, a novel Kahalalide F-derived marine compound.

Authors:
Maria Serova Armand de Gramont Ivan Bieche Maria Eugenia Riveiro Carlos Maria Galmarini Miguel Aracil José Jimeno Sandrine Faivre Eric Raymond

Mar Drugs 2013 Mar 20;11(3):944-59. Epub 2013 Mar 20.

AAREC Filia Research, 1, Paul Verlaine, Boulogne Billancourt 92100, France.

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March 2013

Benchmarking effects of mTOR, PI3K, and dual PI3K/mTOR inhibitors in hepatocellular and renal cell carcinoma models developing resistance to sunitinib and sorafenib.

Authors:
Maria Serova Armand de Gramont Annemilaï Tijeras-Raballand Célia Dos Santos Maria Eugenia Riveiro Khemaies Slimane Sandrine Faivre Eric Raymond

Cancer Chemother Pharmacol 2013 May 12;71(5):1297-307. Epub 2013 Mar 12.

AAREC Filia Research, 1 place Paul Verlaine, 92100 Boulogne-Billancourt, France.

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May 2013

Focus on the role of the CXCL12/CXCR4 chemokine axis in head and neck squamous cell carcinoma.

Authors:
Sébastien Albert Maria Eugenia Riveiro Caroline Halimi Muriel Hourseau Anne Couvelard Maria Serova Béatrix Barry Eric Raymond Sandrine Faivre

Head Neck 2013 Dec 6;35(12):1819-28. Epub 2013 Mar 6.

INSERM U728, RayLab, and Departments of Medical Oncology, Beaujon University Hospital (AP-HP, Paris 7 Diderot), Clichy, France; Department of Head and Neck Surgery, Bichat University Hospital, Paris, France.

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December 2013

Systemic treatment and medical management of metastatic squamous cell carcinoma of the head and neck: review of the literature and proposal for management changes.

Authors:
Frédéric Peyrade Didier Cupissol Lionel Geoffrois Frédéric Rolland Christian Borel Catherine Ciais Sandrine Faivre Joël Guigay

Oral Oncol 2013 Jun 13;49(6):482-91. Epub 2013 Feb 13.

Department of Medical Oncology, Centre Antoine Lacassagne, Nice, France.

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June 2013

Induction chemotherapy challenges for head and neck cancer.

Authors:
Sandrine Faivre Sébastien Albert Eric Raymond

Lancet Oncol 2013 Mar 13;14(3):188-9. Epub 2013 Feb 13.

Department of Medical Oncology, Beaujon University Hospital, Clichy; Service de Cancérologie, Hôpital Beaujon, 100 Bd du General-Leclerc, 92118 CLICHY Cedex, France.

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March 2013

Reappraisal of the risks and benefits of major liver resection in patients with initially unresectable colorectal liver metastases.

Authors:
François Cauchy Béatrice Aussilhou Safi Dokmak David Fuks Sébastien Gaujoux Olivier Farges Sandrine Faivre Daniel Lepillé Jacques Belghiti

Ann Surg 2012 Nov;256(5):746-52; discussion 752-4

Department of HPB Surgery & Liver Transplantation, Beaujon Hospital, Clichy, France.

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November 2012

Resistance to targeted therapies in pancreatic neuroendocrine tumors (PNETs): molecular basis, preclinical data, and counteracting strategies.

Authors:
Annemilaï Tijeras-Raballand Cindy Neuzillet Anne Couvelard Maria Serova Armand de Gramont Pascal Hammel Eric Raymond Sandrine Faivre

Target Oncol 2012 Sep 25;7(3):173-81. Epub 2012 Aug 25.

Pre Clinical Department, AAREC Filia Research, Boulogne-Billancourt, France.

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September 2012

Targeting neuroendocrine tumor: mixing standard options with novel therapies.

Authors:
Eric Raymond Chantal Dreyer Sandrine Faivre

Target Oncol 2012 Sep 24;7(3):151-2. Epub 2012 Aug 24.

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September 2012

New treatment options with cytotoxic agents in neuroendocrine tumours.

Authors:
Pascal Hammel Olivia Hentic Cindy Neuzillet Sandrine Faivre Eric Raymond Philippe Ruszniewski

Target Oncol 2012 Sep 22;7(3):169-72. Epub 2012 Aug 22.

Service de Gastroenterologie-Pancreatologie, Hôpital Beaujon, AP-HP, Faculté Denis Diderot (Paris VII), Clichy, France.

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September 2012

Prognostic value of the chemokine receptor CXCR4 and epithelial-to-mesenchymal transition in patients with squamous cell carcinoma of the mobile tongue.

Authors:
Sébastien Albert Muriel Hourseau Caroline Halimi Maria Serova Véronique Descatoire Béatrix Barry Anne Couvelard Maria Eugenia Riveiro Annemilaï Tijeras-Raballand Armand de Gramont Eric Raymond Sandrine Faivre

Oral Oncol 2012 Dec 7;48(12):1263-71. Epub 2012 Jul 7.

INSERM U728, RayLab, and Departments of Medical Oncology, Beaujon University Hospital (AP-HP - Paris 7 Diderot), Clichy, France.

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December 2012

Sunitinib in pancreatic neuroendocrine tumors.

Authors:
Eric Raymond Pascal Hammel Chantal Dreyer Christian Maatescu Olivia Hentic Philippe Ruszniewski Sandrine Faivre

Target Oncol 2012 Jun 2;7(2):117-25. Epub 2012 Jun 2.

Department of Medical Oncology (INSERM U728-Paris 7 Diderot University), Beaujon University Hospital, 100 boulevard du Général Leclerc, 92110, Clichy, France.

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June 2012

Imaging response in neuroendocrine tumors treated with targeted therapies: the experience of sunitinib.

Authors:
Sandrine Faivre Maxime Ronot Chantal Dreyer Camille Serrate Olivia Hentic Mohamed Bouattour Onorina Bruno Anne Couvelard Valérie Vilgrain Eric Raymond

Target Oncol 2012 Jun 15;7(2):127-33. Epub 2012 May 15.

Department of Medical Oncology, Beaujon University Hospital (AP-HP-Paris 7 Diderot), Clichy, France.

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June 2012

Pure and mixed fibrolamellar hepatocellular carcinomas differ in natural history and prognosis after complete surgical resection.

Authors:
Gabriel G Malouf Laurence Brugières Marie-Cécile Le Deley Sandrine Faivre Monique Fabre Valérie Paradis Isabelle Aerts Christophe Le Tourneau Chantal Dreyer Sophie Branchereau Jacques Belghiti Eric Raymond

Cancer 2012 Oct 13;118(20):4981-90. Epub 2012 Mar 13.

Department of Medical Oncology, Beaujon University Hospital, Clichy, France.

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October 2012

Sunitinib in advanced pancreatic neuroendocrine tumors: latest evidence and clinical potential.

Authors:
Catherine Delbaldo Sandrine Faivre Chantal Dreyer Eric Raymond

Ther Adv Med Oncol 2012 Jan;4(1):9-18

Department of Medical Oncology, Univ Paris Diderot, Sorbonne Paris Cité, INSERM U728, and Beaujon and Louis Mourier University Hospital (Assistance Publique Hopitaux de Paris, Paris 7 Diderot), Clichy, France.

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January 2012

Biological and prognostic relevance of mitogen-activated protein kinases in pancreatic adenocarcinoma.

Authors:
Adriana Handra-Luca Claude Lesty Pascal Hammel Alain Sauvanet Vinciane Rebours Antoine Martin Remi Fagard Jean-François Fléjou Sandrine Faivre Pierre Bédossa Philippe Ruszniewski Anne Couvelard

Pancreas 2012 Apr;41(3):416-21

Service d'Anatomie Pathologique, APHP Groupe Hospitalier Universitaire Nord, Bobigny, France.

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April 2012

Neither preoperative computed tomography nor intra-operative examination can predict metastatic lymph node in the hepatic pedicle in patients with colorectal liver metastasis.

Authors:
Cédric Rau Benjamin Blanc Maxime Ronot Safi Dokmak Béatrice Aussilhou Sandrine Faivre Valérie Vilgrain Valérie Paradis Jacques Belghiti

Ann Surg Oncol 2012 Jan 12;19(1):163-8. Epub 2011 Aug 12.

Department of HPB Surgery, Beaujon Hospital, Clichy, France.

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January 2012

Phase II study of cetuximab as first-line single-drug therapy in patients with unresectable squamous cell carcinoma of the skin.

Authors:
Eve Maubec Peter Petrow Isabelle Scheer-Senyarich Pierre Duvillard Ludovic Lacroix Julien Gelly Agnès Certain Xavier Duval Béatrice Crickx Valérie Buffard Nicole Basset-Seguin Pierre Saez Anne-Bénédicte Duval-Modeste Henri Adamski Sandrine Mansard Florent Grange Anne Dompmartin Sandrine Faivre France Mentré Marie-Françoise Avril

J Clin Oncol 2011 Sep 1;29(25):3419-26. Epub 2011 Aug 1.

Hôpital Bichat, Service de Dermatologie, 46 rue Henri Huchard, Paris, cedex 75877, France.

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September 2011

Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib.

Authors:
Charles S Harmon Samuel E DePrimo Eric Raymond Ann-Lii Cheng Eveline Boucher Jean-Yves Douillard Ho Y Lim Jun S Kim Maria José Lechuga Silvana Lanzalone Xun Lin Sandrine Faivre

J Transl Med 2011 Jul 25;9:120. Epub 2011 Jul 25.

Pfizer Oncology, La Jolla, CA, USA.

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July 2011

Spectrum of cellular responses to pyriplatin, a monofunctional cationic antineoplastic platinum(II) compound, in human cancer cells.

Authors:
Katherine S Lovejoy Maria Serova Ivan Bieche Shahin Emami Maurizio D'Incalci Massimo Broggini Eugenio Erba Christian Gespach Esteban Cvitkovic Sandrine Faivre Eric Raymond Stephen J Lippard

Mol Cancer Ther 2011 Sep 12;10(9):1709-19. Epub 2011 Jul 12.

Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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September 2011

[PI3K-AKT-mTOR pathway and cancer].

Authors:
Laetitia Coutte Chantal Dreyer Marie-Paule Sablin Sandrine Faivre Eric Raymond

Bull Cancer 2012 Feb;99(2):173-80

Hôpital Beaujon, service interhospitalier de cancérologie, 100, boulevard du Général-Leclerc, 92118 Clichy Cedex, France.

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February 2012

Predictive biomarkers for the activity of mammalian target of rapamycin (mTOR) inhibitors.

Authors:
Catherine Delbaldo Sébastien Albert Chantal Dreyer Marie-Paule Sablin Maria Serova Eric Raymond Sandrine Faivre

Target Oncol 2011 Jun 28;6(2):119-24. Epub 2011 Apr 28.

Paris Nord Val de Seine University Hospitals, Clichy, Paris, France.

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June 2011

Changes in tumor density in patients with advanced hepatocellular carcinoma treated with sunitinib.

Authors:
Sandrine Faivre Magaly Zappa Valérie Vilgrain Eveline Boucher Jean-Yves Douillard Ho Y Lim Jun S Kim Seock-Ah Im Yoon-Koo Kang Mohamed Bouattour Safi Dokmak Chantal Dreyer Marie-Paule Sablin Camille Serrate Ann-Lii Cheng Silvana Lanzalone Xun Lin Maria J Lechuga Eric Raymond

Clin Cancer Res 2011 Jul 29;17(13):4504-12. Epub 2011 Apr 29.

Beaujon University Hospital, Clichy, France.

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July 2011

Complete regression of locally advanced hepatocellular carcinoma induced by sorafenib allowing curative resection.

Authors:
Sabine Irtan Xavier Chopin-Laly Maxime Ronot Sandrine Faivre Valérie Paradis Jacques Belghiti

Liver Int 2011 May 11;31(5):740-3. Epub 2011 Jan 11.

Department of HBP Surgery, Assistance Publique-Hôpitaux de Paris, University of Paris, Paris, France.

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May 2011

Novel molecular therapies in hepatocellular carcinoma.

Authors:
Sandrine Faivre Mohamed Bouattour Eric Raymond

Liver Int 2011 Jan;31 Suppl 1:151-60

Department of Medical Oncology, Beaujon/Bichat University Hospital, Assistance Publique-Hôpitaux de Paris, University INSERM U728, Paris 7, Clichy, France.

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January 2011

[Targeted therapies in colorectal cancer].

Authors:
Marie-Paule Sablin Chantal Dreyer Camélia Colichi Mohamed Bouattour Sandrine Faivre

Rev Prat 2010 Oct;60(8):1094-9

Service interhospitalier de cancérologie Bichat-Beaujon, Hôpital Beaujon, AP-HP, 92118 Clichy Cedex.

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October 2010

Epithelial-to-mesenchymal transition and acquired resistance to sunitinib in a patient with hepatocellular carcinoma.

Authors:
Hélène Marijon Safi Dokmak Valérie Paradis Magaly Zappa Ivan Bieche Mohamed Bouattour Eric Raymond Sandrine Faivre

J Hepatol 2011 May 2;54(5):1073-8. Epub 2010 Dec 2.

Department of Medical Oncology (APHP), Beaujon University Hospital, Paris 7 Diderot, Clichy, France.

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May 2011

Novel anticancer agents in clinical trials for well-differentiated neuroendocrine tumors.

Authors:
Sandrine Faivre Marie-Paule Sablin Chantal Dreyer Eric Raymond

Endocrinol Metab Clin North Am 2010 Dec;39(4):811-26

Department of Medical Oncology, Beaujon University Hospital (AP-HP, Paris 7 Diderot), Clichy, France.

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December 2010

Phase I evaluation of seliciclib (R-roscovitine), a novel oral cyclin-dependent kinase inhibitor, in patients with advanced malignancies.

Authors:
Christophe Le Tourneau Sandrine Faivre Valérie Laurence Catherine Delbaldo Karina Vera Veronique Girre Judy Chiao Sian Armour Sheelagh Frame Simon R Green Athos Gianella-Borradori Veronique Diéras Eric Raymond

Eur J Cancer 2010 Dec 6;46(18):3243-50. Epub 2010 Sep 6.

Department of Medical Oncology, Beaujon University Hospital, Paris 7, AP-HP, Clichy, France.

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December 2010

Benefits from pharmacological and pharmacokinetic properties of sunitinib for clinical development.

Authors:
Marie-Paule Sablin Chantal Dreyer Camelia Colichi Mohammed Bouattour Catherine Delbaldo Sandrine Faivre Eric Raymond

Expert Opin Drug Metab Toxicol 2010 Aug;6(8):1005-15

U Inserm Université Paris VII, Hôpital Beaujon, Paris, France.

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August 2010

New inhibitors of the mammalian target of rapamycin signaling pathway for cancer.

Authors:
Sébastien Albert Maria Serova Chantal Dreyer Marie-Paule Sablin Sandrine Faivre Eric Raymond

Expert Opin Investig Drugs 2010 Aug;19(8):919-30

Service Inter-Hospitalier de Cancérologie Bichat-Beaujon (SIHC), Laboratoire de pharmacobiologie des anticancereux (RayLab), Paris, France.

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August 2010

Epithelial-to-mesenchymal transition and oncogenic Ras expression in resistance to the protein kinase Cbeta inhibitor enzastaurin in colon cancer cells.

Authors:
Maria Serova Lucile Astorgues-Xerri Ivan Bieche Sebastien Albert Michel Vidaud Karim A Benhadji Shahin Emami Dominique Vidaud Pascal Hammel Nathalie Theou-Anton Christian Gespach Sandrine Faivre Eric Raymond

Mol Cancer Ther 2010 May 20;9(5):1308-17. Epub 2010 Apr 20.

INSERM U728, RayLab, Beaujon University Hospital (AP-HP-Paris 7 Diderot), Clichy, France.

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May 2010

[Targeted therapies in hepatocellular carcinoma].

Authors:
Mohamed Bouattour Hélène Marijon Chantal Dreyer Sandrine Faivre Eric Raymond

Presse Med 2010 Jul-Aug;39(7-8):753-64. Epub 2010 Apr 7.

Service inter-hospitalier de cancérologie Bichat-Beaujon, hôpital Beaujon, 92110 Clichy, France.

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July 2010

Phase II study of sunitinib in recurrent or metastatic squamous cell carcinoma of the head and neck: GORTEC 2006-01.

Authors:
Jean-Pascal H Machiels Stéphanie Henry Sylvie Zanetta Marie-Christine Kaminsky Nicolas Michoux Denis Rommel Sandra Schmitz Emmanuelle Bompas Anne-Françoise Dillies Sandrine Faivre Anne Moxhon Thierry Duprez Joel Guigay

J Clin Oncol 2010 Jan 16;28(1):21-8. Epub 2009 Nov 16.

Medical Oncology Unit, Université Catholique de Louvain, Cliniques Universitaires Saint-Luc, 10 Avenue Hippocrate, 1200 Brussels, Belgium.

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January 2010

Sunitinib paves the way for targeted therapies in neuroendocrine tumors.

Authors:
Eric Raymond Sandrine Faivre Pascal Hammel Philippe Ruszniewski

Target Oncol 2009 Dec 13;4(4):253-4. Epub 2009 Nov 13.

Department of Medical Oncology and Gastroenterology, Beaujon University Hospital, Clichy, France.

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December 2009

Sunitinib in hepatocellular carcinoma: redefining appropriate dosing, schedule, and activity end points.

Authors:
Sandrine J Faivre Mohamed Bouattour Chantal Dreyer Eric Raymond

J Clin Oncol 2009 Dec 9;27(35):e248-50; author reply e251-2. Epub 2009 Nov 9.

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December 2009

Reports of clinical benefit of plitidepsin (Aplidine), a new marine-derived anticancer agent, in patients with advanced medullary thyroid carcinoma.

Authors:
Christophe Le Tourneau Sandrine Faivre Eva Ciruelos María J Domínguez José A López-Martín Miguel A Izquierdo José Jimeno Eric Raymond

Am J Clin Oncol 2010 Apr;33(2):132-6

Department of Medical Oncology, Beaujon University Hospital, Clichy, France.

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April 2010

Benefit-risk assessment of sunitinib in gastrointestinal stromal tumours and renal cancer.

Authors:
Nathalie Theou-Anton Sandrine Faivre Chantal Dreyer Eric Raymond

Drug Saf 2009 ;32(9):717-34

Department of Pharmacy, Beaujon University Hospital-Paris 7, Hôpital Beaujon, Clichy, France.

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October 2009

Safety and efficacy of sunitinib in patients with advanced hepatocellular carcinoma: an open-label, multicentre, phase II study.

Authors:
Sandrine Faivre Eric Raymond Eveline Boucher Jean Douillard Ho Y Lim Jun S Kim Magaly Zappa Silvana Lanzalone Xun Lin Samuel Deprimo Charles Harmon Ana Ruiz-Garcia Maria J Lechuga Ann Lii Cheng

Lancet Oncol 2009 Aug 6;10(8):794-800. Epub 2009 Jul 6.

Beaujon University Hospital, Clichy, France.

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August 2009

Temozolomide: a safe and effective treatment for malignant digestive endocrine tumors.

Authors:
Frédérique Maire Pascal Hammel Sandrine Faivre Olivia Hentic Lorena Yapur Béatrice Larroque Anne Couvelard Magaly Zappa Eric Raymond Philippe Lévy Philippe Ruszniewski

Neuroendocrinology 2009 11;90(1):67-72. Epub 2009 Jun 11.

Pôle des Maladies de l'Appareil Digestif, Service de Gastroentérologie-Pancréatologie, Hôpital Beaujon, Clichy, France.

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September 2009

Epithelial-to-mesenchymal transition and resistance to ingenol 3-angelate, a novel protein kinase C modulator, in colon cancer cells.

Authors:
Aïda Ghoul Maria Serova Lucile Astorgues-Xerri Ivan Bieche Guilhem Bousquet Mariana Varna Michel Vidaud Edelmira Phillips Sophie Weill Karim A Benhadji François Lokiec Esteban Cvitkovic Sandrine Faivre Eric Raymond

Cancer Res 2009 May 5;69(10):4260-9. Epub 2009 May 5.

Institut National de la Sante et de la Recherche Medicale U728, RayLab, and Department of Medical Oncology, Beaujon and Saint-Louis University Hospital (AP-HP-Paris 7 Diderot), Clichy, France.

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May 2009

Preoperative liver hypertrophy induced by portal flow occlusion before major hepatic resection for colorectal metastases can be impaired by bevacizumab.

Authors:
Béatrice Aussilhou Safi Dokmak Sandrine Faivre Valérie Paradis Valérie Vilgrain Jacques Belghiti

Ann Surg Oncol 2009 Jun 11;16(6):1553-9. Epub 2009 Apr 11.

Department of HPB Surgery, Beaujon Hospital, University Paris, Clichy, France.

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June 2009

Randomized trial of induction chemotherapy with cisplatin and 5-fluorouracil with or without docetaxel for larynx preservation.

Authors:
Yoann Pointreau Pascal Garaud Sophie Chapet Christian Sire Claude Tuchais Jacques Tortochaux Sandrine Faivre Stephane Guerrif Marc Alfonsi Gilles Calais

J Natl Cancer Inst 2009 Apr 24;101(7):498-506. Epub 2009 Mar 24.

Centre Hospitalier Régional et Universitaire, Henry Kaplan Center, Clinique d'Oncologie et de Radiothérapie, Tours, France.

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April 2009

Markers involved in resistance to cytotoxics and targeted therapeutics in pancreatic cancer.

Authors:
Ghassan El Maalouf Christophe Le Tourneau Georges Nicolas Batty Sandrine Faivre Eric Raymond

Cancer Treat Rev 2009 Apr 21;35(2):167-74. Epub 2008 Nov 21.

Department of Medical Oncology, Service Inter-Hospitalier de Cancérologie Bichat-Beaujon, Beaujon University Hospital, Hôpital Beaujon, 100 Boulevard du Général Leclerc, 92118 Clichy Cedex, France.

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April 2009

Mechanism of action of rapalogues: the antiangiogenic hypothesis.

Authors:
Sandrine Faivre Eric Raymond

Expert Opin Investig Drugs 2008 Nov;17(11):1619-21

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November 2008

Effects of protein kinase C modulation by PEP005, a novel ingenol angelate, on mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling in cancer cells.

Authors:
Maria Serova Aïda Ghoul Karim A Benhadji Sandrine Faivre Christophe Le Tourneau Esteban Cvitkovic Francois Lokiec Janet Lord Steven M Ogbourne Fabien Calvo Eric Raymond

Mol Cancer Ther 2008 Apr;7(4):915-22

Institut National de la Sante et de la Recherche Medicale-U728-RAYLAB and Department of Medical Oncology, Beaujon University Hospital, Clichy, France.

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April 2008

Sunitinib: a novel tyrosine kinase inhibitor. A brief review of its therapeutic potential in the treatment of renal carcinoma and gastrointestinal stromal tumors (GIST).

Authors:
Christophe Le Tourneau Eric Raymond Sandrine Faivre

Ther Clin Risk Manag 2007 Jun;3(2):341-8

Department of Medical Oncology Hôpital Beaujon, Clichy, France.

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June 2007

Phase I pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors.

Authors:
Anne O'Donnell Sandrine Faivre Howard A Burris Daniel Rea Vassiliki Papadimitrakopoulou Nicholas Shand Heidi A Lane Katharine Hazell Ulrike Zoellner John M Kovarik Cathryn Brock Suzanne Jones Eric Raymond Ian Judson

J Clin Oncol 2008 Apr 10;26(10):1588-95. Epub 2008 Mar 10.

Royal Marsden Hospital, Sutton, Surrey, UK.

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April 2008