Publications by authors named "Sandra Tuyaerts"

36Publications

Editorial: Approaches to Advance Cancer Vaccines to Clinical Utility.

Front Immunol 2019 27;10:2032. Epub 2019 Aug 27.

Division of Gynecologic Oncology, Department of Oncology, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.3389/fimmu.2019.02032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718470PMC
October 2020

Contribution of Aging, Obesity, and Microbiota on Tumor Immunotherapy Efficacy and Toxicity.

Int J Mol Sci 2019 Jul 23;20(14). Epub 2019 Jul 23.

Division of Gynecologic Oncology, Department of Oncology, KU Leuven, 3000 Leuven, Belgium.

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http://dx.doi.org/10.3390/ijms20143586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678743PMC
July 2019

Endometrial Stromal Sarcomas: A Revision of Their Potential as Targets for Immunotherapy.

Vaccines (Basel) 2018 Aug 25;6(3). Epub 2018 Aug 25.

Division of Gynecologic Oncology, Department of Oncology, KU Leuven, 3000 Leuven, Belgium.

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http://dx.doi.org/10.3390/vaccines6030056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161160PMC
August 2018

In Vitro Assessment of the Expression and T Cell Immunogenicity of the Tumor-Associated Antigens BORIS, MUC1, hTERT, MAGE-A3 and Sp17 in Uterine Cancer.

Int J Mol Sci 2016 Sep 9;17(9). Epub 2016 Sep 9.

Department of Oncology, Gynecologic Oncology, Campus Gasthuisberg, Sandra Tuyaerts, KU Leuven-University of Leuven, Herestraat 49 Box 818, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.3390/ijms17091525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037800PMC
September 2016

mRNA Electroporation of Dendritic Cells with WT1, Survivin, and TriMix (a Mixture of caTLR4, CD40L, and CD70).

Methods Mol Biol 2016 ;1428:277-83

Laboratory of Gynecologic Oncology, Department of Oncology, KU Leuven, Leuven Cancer Institute, Leuven, Belgium.

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http://dx.doi.org/10.1007/978-1-4939-3625-0_18DOI Listing
December 2017

Potential Therapeutic Targets in Uterine Sarcomas.

Sarcoma 2015 21;2015:243298. Epub 2015 Oct 21.

Department of Oncology, Gynaecologic Oncology, KU Leuven (University of Leuven), 3000 Leuven, Belgium ; Department of Obstetrics and Gynaecology, University Hospitals Leuven, 3000 Leuven, Belgium ; Center for Gynaecologic Oncology Amsterdam (CGOA), Antoni van Leeuwenhoek-Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.

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http://dx.doi.org/10.1155/2015/243298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632006PMC
November 2015

In Vitro Validation of Survivin as Target Tumor-associated Antigen for Immunotherapy in Uterine Cancer.

J Immunother 2015 Jul-Aug;38(6):239-49

*Department of Oncology, Gynecologic Oncology, KU Leuven-University of Leuven †Department of Gynecology and Obstetrics, Division Gynecologic Oncology, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1097/CJI.0000000000000085DOI Listing
February 2016

Dendritic cell immunotherapy in uterine cancer.

Hum Vaccin Immunother 2014 ;10(7):1822-7

a Department of Oncology; Leuven Cancer Institute; KU Leuven; Leuven, Belgium.

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http://dx.doi.org/10.4161/hv.28716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186030PMC
July 2015

Wilms' Tumor Gene 1 (WT1)--loaded dendritic cell immunotherapy in patients with uterine tumors: a phase I/II clinical trial.

Anticancer Res 2013 Dec;33(12):5495-500

KU Leuven, Laboratory of Pediatric Immunology, Onderwijs & Navorsing 1, Herestraat 49 bus 811, 3000 Leuven, Belgium.

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December 2013

Immunological response after WT1 mRNA-loaded dendritic cell immunotherapy in ovarian carcinoma and carcinosarcoma.

Anticancer Res 2013 Sep;33(9):3855-9

KU Leuven, Laboratory of Pediatric Immunology, Onderwijs & Navorsing 1, Herestraat 49 bus 811, 3000 Leuven, Belgium.

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September 2013

Epitope and HLA-type independent monitoring of antigen-specific T-cells after treatment with dendritic cells presenting full-length tumor antigens.

J Immunol Methods 2012 Mar 16;377(1-2):23-36. Epub 2012 Jan 16.

Laboratory of Molecular and Cellular Therapy, Department of Physiology-Immunology, Medical School of the Vrije Universiteit Brussel, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.jim.2011.12.010DOI Listing
March 2012

Dendritic cell therapy for oncology roundtable conference.

Authors:
Sandra Tuyaerts

J Immune Based Ther Vaccines 2011 Jan 12;9(1). Epub 2011 Jan 12.

Laboratory of Experimental Gynaecology, Department of Woman & Child, Catholic University of Leuven (K,U, Leuven), Belgium.

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http://dx.doi.org/10.1186/1476-8518-9-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027086PMC
January 2011

Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients.

Clin Cancer Res 2009 May 5;15(10):3366-75. Epub 2009 May 5.

Laboratory of Molecular and Cellular Therapy, Department of Physiology-Immunology, Medical School of the Vrije Universiteit Brussel, Brussels, Belgium.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-2982DOI Listing
May 2009

Enhancing the T-cell stimulatory capacity of human dendritic cells by co-electroporation with CD40L, CD70 and constitutively active TLR4 encoding mRNA.

Mol Ther 2008 Jun 22;16(6):1170-80. Epub 2008 Apr 22.

Laboratory of Molecular and Cellular Therapy, Department of Physiology-Immunology, Medical School of the Vrije Universiteit Brussel, Brussels, Belgium.

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http://linkinghub.elsevier.com/retrieve/pii/S152500161631744
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http://dx.doi.org/10.1038/mt.2008.77DOI Listing
June 2008

Delivery of tumor-antigen-encoding mRNA into dendritic cells for vaccination.

Methods Mol Biol 2008 ;423:155-63

Department of Physiology and Immunology, Medical School of the Vrije Universiteit Brussel , Brussels, Belgium.

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http://dx.doi.org/10.1007/978-1-59745-194-9_10DOI Listing
June 2008

Current approaches in dendritic cell generation and future implications for cancer immunotherapy.

Cancer Immunol Immunother 2007 Oct 15;56(10):1513-37. Epub 2007 May 15.

Laboratory of Molecular and Cellular Therapy, Department of Physiology and Immunology, Medical School of the Vrije Universiteit Brussel, Laarbeeklaan 103/E, 1090, Brussels, Belgium.

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http://dx.doi.org/10.1007/s00262-007-0334-zDOI Listing
October 2007

Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells.

J Leukoc Biol 2007 Jul 20;82(1):93-105. Epub 2007 Apr 20.

Laboratory of Molecular and Cellular Therapy, Department of Physiology and Immunology, Medical School of the Vrije Universiteit Brussel, Laarbeeklaan 103/E, 1090 Brussels, Belgium.

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http://dx.doi.org/10.1189/jlb.0906568DOI Listing
July 2007

CD83 expression on dendritic cells and T cells: correlation with effective immune responses.

Eur J Immunol 2007 Mar;37(3):686-95

Laboratory of Molecular and Cellular Therapy, Department of Physiology and Immunology, Medical School of the Vrije Universiteit Brussel, Brussels, Belgium.

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http://dx.doi.org/10.1002/eji.200636535DOI Listing
March 2007

Melan-A/MART-1-specific CD4 T cells in melanoma patients: identification of new epitopes and ex vivo visualization of specific T cells by MHC class II tetramers.

J Immunol 2006 Nov;177(10):6769-79

Division of Clinical Onco-Immunology, Ludwig Institute for Cancer Research, Lausanne Branch, University Hospital, Lausanne, Switzerland.

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http://dx.doi.org/10.4049/jimmunol.177.10.6769DOI Listing
November 2006

Dendritic cells differentiated in the presence of IFN-{beta} and IL-3 are potent inducers of an antigen-specific CD8+ T cell response.

J Leukoc Biol 2005 Oct 21;78(4):898-908. Epub 2005 Jul 21.

Department of Physiology and Immunology, Medical School of the Vrije Universiteit Brussel, 1090 Brussels, Belgium.

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http://doi.wiley.com/10.1189/jlb.0105052
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http://dx.doi.org/10.1189/jlb.0105052DOI Listing
October 2005

Side-by-side comparison of lentivirally transduced and mRNA-electroporated dendritic cells: implications for cancer immunotherapy protocols.

Mol Ther 2004 Oct;10(4):768-79

Laboratory of Molecular and Cellular Therapy, Department of Physiology-Immunology, Medical School of the Vrije Universiteit Brussel, Laarbeeklaan 103/E, 1090 Brussels, Belgium.

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http://linkinghub.elsevier.com/retrieve/pii/S152500160401346
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http://dx.doi.org/10.1016/j.ymthe.2004.07.017DOI Listing
October 2004

Activation of monocytes via the CD14 receptor leads to the enhanced lentiviral transduction of immature dendritic cells.

Hum Gene Ther 2004 Jun;15(6):562-73

Laboratory of Molecular and Cellular Therapy, Department of Physiology and Immunology, Medical School of the Vrije Universiteit Brussel (V.U.B.), Laarbeeklaan 103/E, 1090 Brussels, Belgium.

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http://dx.doi.org/10.1089/104303404323142015DOI Listing
June 2004

Messenger RNA-electroporated dendritic cells presenting MAGE-A3 simultaneously in HLA class I and class II molecules.

J Immunol 2004 Jun;172(11):6649-57

Laboratory of Molecular and Cellular Therapy, Department of Physiology-Immunology, Medical School of the Vrije Universiteit Brussel, Brussels, Belgium.

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http://www.jimmunol.org/content/172/11/6649.full.pdf
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http://dx.doi.org/10.4049/jimmunol.172.11.6649DOI Listing
June 2004

Efficient presentation of known HLA class II-restricted MAGE-A3 epitopes by dendritic cells electroporated with messenger RNA encoding an invariant chain with genetic exchange of class II-associated invariant chain peptide.

Cancer Res 2003 Sep;63(17):5587-94

Laboratory of Molecular and Cellular Therapy, Department of Physiology-Immunology, Medical School of the Vrije Universiteit Brussel, 1090 Brussels, Belgium.

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September 2003

Induction of Influenza Matrix Protein 1 and MelanA-specific T lymphocytes in vitro using mRNA-electroporated dendritic cells.

Cancer Gene Ther 2003 Sep;10(9):696-706

Laboratory of Molecular and Cellular Therapy, Department of Physiology-Immunology, Medical School of the Vrije Universiteit Brussel (VUB), Laarbeeklaan 103/E, 1090 Brussels, Belgium.

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http://dx.doi.org/10.1038/sj.cgt.7700622DOI Listing
September 2003

Generation of large numbers of dendritic cells in a closed system using Cell Factories.

J Immunol Methods 2002 Jun;264(1-2):135-51

Laboratory of Molecular and Cellular Therapy, Department of Physiology-Immunology, Medical School of the Vrije Universiteit Brussel (VUB), Laarbeeklaan 103/E, Brussels, Belgium.

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http://dx.doi.org/10.1016/s0022-1759(02)00099-6DOI Listing
June 2002