Publications by authors named "Sandra M Cardoso"

62Publications

Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer's Disease Agents.

Authors:
Viviana Poliseno Sílvia Chaves Leonardo Brunetti Fulvio Loiodice Antonio Carrieri Antonio Laghezza Paolo Tortorella João D Magalhães Sandra M Cardoso M Amélia Santos Luca Piemontese

Biomolecules 2021 Jan 15;11(1). Epub 2021 Jan 15.

Department of Pharmacy and Pharmaceutical Sciences, University of Bari "A. Moro", via E. Orabona 4, 70125 Bari, Italy.

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January 2021

Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation, and Alzheimer's disease features in cortical neurons.

Authors:
Diana F Silva Emanuel Candeias A Raquel Esteves João D Magalhães I Luísa Ferreira Daniela Nunes-Costa A Cristina Rego Nuno Empadinhas Sandra M Cardoso

J Neuroinflammation 2020 Nov 5;17(1):332. Epub 2020 Nov 5.

CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Largo Marquês de Pombal, 3004-517, Coimbra, Portugal.

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November 2020

Donepezil-based hybrids as multifunctional anti-Alzheimer's disease chelating agents: Effect of positional isomerization.

Authors:
Marina Costa Romane Josselin Diana F Silva Sandra M Cardoso Nóra V May Sílvia Chaves M Amélia Santos

J Inorg Biochem 2020 05 16;206:111039. Epub 2020 Feb 16.

Centro de Química Estrutural and Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, Av, Rovisco Pais 1, 1049-001 Lisboa, Portugal. Electronic address:

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May 2020

The Mitochondrial Ribosome: A World of Opportunities for Mitochondrial Dysfunction Toward Parkinson's Disease.

Authors:
Ana Mafalda Gonçalves Ana Raquel Pereira-Santos Ana Raquel Esteves Sandra M Cardoso Nuno Empadinhas

Antioxid Redox Signal 2021 Mar 31;34(8):694-711. Epub 2020 Mar 31.

CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.

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March 2021

Design, Synthesis, and In Vitro Evaluation of Hydroxybenzimidazole-Donepezil Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.

Authors:
Sílvia Chaves Simonetta Resta Federica Rinaldo Marina Costa Romane Josselin Karolina Gwizdala Luca Piemontese Vito Capriati A Raquel Pereira-Santos Sandra M Cardoso M Amélia Santos

Molecules 2020 Feb 22;25(4). Epub 2020 Feb 22.

Centro de Química Estrutural and Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal.

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February 2020

Novel tacrine-benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer's Disease.

Authors:
Gaia Fancellu Karam Chand Daniel Tomás Elisabetta Orlandini Luca Piemontese Diana F Silva Sandra M Cardoso Sílvia Chaves M Amélia Santos

J Enzyme Inhib Med Chem 2020 Dec;35(1):211-226

Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal.

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December 2020

Is Alzheimer's disease an inflammasomopathy?

Authors:
Claudia F Pereira Armanda E Santos Paula I Moreira Ana Catarina Pereira Fabio J Sousa Sandra M Cardoso M Teresa Cruz

Ageing Res Rev 2019 12 29;56:100966. Epub 2019 Sep 29.

CNC - Center for Neuroscience and Cell Biology, University of Coimbra, Rua Larga, Faculty of Medicine, Polo I, 1st Floor, 3004-504, Coimbra, Portugal; CIBB-Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Rua Larga, Faculty of Medicine, Polo I, 1st Floor, 3004-504, Coimbra, Portugal; Faculty of Pharmacy, Azinhaga de Santa Comba, Celas, 3000-548, Coimbra, Portugal. Electronic address:

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December 2019

New Multitarget Hybrids Bearing Tacrine and Phenylbenzothiazole Motifs as Potential Drug Candidates for Alzheimer's Disease.

Authors:
Rajeshwari Rajeshwari Karam Chand Emanuel Candeias Sandra M Cardoso Sílvia Chaves M Amélia Santos

Molecules 2019 Feb 7;24(3). Epub 2019 Feb 7.

Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa, Portugal.

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February 2019

The Role of Beclin-1 Acetylation on Autophagic Flux in Alzheimer's Disease.

Authors:
A Raquel Esteves Filipa Filipe João D Magalhães Diana F Silva Sandra M Cardoso

Mol Neurobiol 2019 Aug 19;56(8):5654-5670. Epub 2019 Jan 19.

CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.

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August 2019

Mild Exercise Differently Affects Proteostasis and Oxidative Stress on Motor Areas During Neurodegeneration: A Comparative Study of Three Treadmill Running Protocols.

Authors:
Karla P Melo Carolliny M Silva Michael F Almeida Rodrigo S Chaves Tania Marcourakis Sandra M Cardoso Marilene Demasi Luis E S Netto Merari F R Ferrari

Neurotox Res 2019 Feb 1;35(2):410-420. Epub 2018 Oct 1.

Departamento de Genetica e Biologia Evolutiva, Instituto de Biociencias, Universidade de Sao Paulo, Rua do Matao, 277, Cidade Universitaria, Sao Paulo, SP, 05508-090, Brazil.

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February 2019

Tacrine-deferiprone hybrids as multi-target-directed metal chelators against Alzheimer's disease: a two-in-one drug.

Authors:
Karam Chand Rajeshwari Emanuel Candeias Sandra M Cardoso Sílvia Chaves M Amélia Santos

Metallomics 2018 10 5;10(10):1460-1475. Epub 2018 Sep 5.

Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisbon, Portugal.

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October 2018

Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's drug candidates.

Authors:
Luca Piemontese Daniel Tomás Asha Hiremathad Vito Capriati Emanuel Candeias Sandra M Cardoso Sílvia Chaves M Amélia Santos

J Enzyme Inhib Med Chem 2018 Dec;33(1):1212-1224

a Centro de Química Estrutural, Instituto Superior Técnico , Universidade de Lisboa , Lisbon , Portugal.

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December 2018

The Microbiome-Mitochondria Dance in Prodromal Parkinson's Disease.

Authors:
Sandra M Cardoso Nuno Empadinhas

Front Physiol 2018 9;9:471. Epub 2018 May 9.

Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.

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May 2018

Novel Tacrine-Hydroxyphenylbenzimidazole hybrids as potential multitarget drug candidates for Alzheimer's disease.

Authors:
Asha Hiremathad Rangappa S Keri A Raquel Esteves Sandra M Cardoso Sílvia Chaves M Amélia Santos

Eur J Med Chem 2018 Mar 12;148:255-267. Epub 2018 Feb 12.

Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001, Lisboa, Portugal. Electronic address:

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March 2018

Hydroxypyridinone-benzofuran hybrids with potential protective roles for Alzheimer´s disease therapy.

Authors:
Asha Hiremathad Karam Chand Lori Tolayan Rajeshwari Rangappa S Keri A Raquel Esteves Sandra M Cardoso Sílvia Chaves M Amélia Santos

J Inorg Biochem 2018 02 21;179:82-96. Epub 2017 Nov 21.

Centro de Química Estrutural, Instituto Superior Técnico, Universidade Técnica de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa, Portugal. Electronic address:

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February 2018

Effects of mild running on substantia nigra during early neurodegeneration.

Authors:
Michael F Almeida Carolliny M Silva Rodrigo S Chaves Nathan C R Lima Renato S Almeida Karla P Melo Marilene Demasi Tiago Fernandes Edilamar M Oliveira Luis E S Netto Sandra M Cardoso Merari F R Ferrari

J Sports Sci 2018 Jun 12;36(12):1363-1370. Epub 2017 Sep 12.

a Departamento de Genética e Biologia Evolutiva, Instituto de Biociências , Universidade de São Paulo , São Paulo , Brazil.

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June 2018

Mitochondrial Metabolism Regulates Microtubule Acetylome and Autophagy Trough Sirtuin-2: Impact for Parkinson's Disease.

Authors:
Ana R Esteves Daniela M Arduíno Diana F Silva Sofia D Viana Frederico C Pereira Sandra M Cardoso

Mol Neurobiol 2018 02 6;55(2):1440-1462. Epub 2017 Feb 6.

CNC - Center for Neuroscience and Cell Biology, University of Coimbra, Largo Marquês de Pombal, 3004-517, Coimbra, Portugal.

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February 2018

LRRK2 at the Crossroad Between Autophagy and Microtubule Trafficking: Insights into Parkinson's Disease.

Authors:
A Raquel Esteves Sandra M Cardoso

Neuroscientist 2017 Feb 8;23(1):16-26. Epub 2016 Jul 8.

1 CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.

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February 2017

New Tacrine Hybrids with Natural-Based Cysteine Derivatives as Multitargeted Drugs for Potential Treatment of Alzheimer's Disease.

Authors:
Rangappa S Keri Catarina Quintanova Sílvia Chaves Diana F Silva Sandra M Cardoso M Amélia Santos

Chem Biol Drug Des 2016 Jan 29;87(1):101-11. Epub 2015 Sep 29.

Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001, Lisboa, Portugal.

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January 2016

A cybrid cell model for the assessment of the link between mitochondrial deficits and sporadic Parkinson's disease.

Authors:
Daniela M Arduíno A Raquel Esteves Russell H Swerdlow Sandra M Cardoso

Methods Mol Biol 2015 ;1265:415-24

Department of Chemistry and Biochemistry, Gene Center Munich, Ludwig-Maximilians-Universität München, Feodor-Lynen-Str. 25, 81377, Munich, Germany,

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October 2015