Dr Sandra D Anderson, PhD, DSc, MD (Hon) - University of Sydney Faculty of Medicine and Health - Clinical Professor

Dr Sandra D Anderson

PhD, DSc, MD (Hon)

University of Sydney Faculty of Medicine and Health

Clinical Professor

Sydney, NSW | Australia

Main Specialties: Pediatric Pulmonology, Pharmacology, Pulmonary Disease, Sports Medicine

Additional Specialties: bronchial provocation, asthma

ORCID logohttps://orcid.org/0000-0002-6308-8770


Top Author

Dr Sandra D Anderson, PhD, DSc, MD (Hon) - University of Sydney Faculty of Medicine and Health - Clinical Professor

Dr Sandra D Anderson

PhD, DSc, MD (Hon)

Introduction

Sandra received a BSc (Sydney) in Physiology and Microbiology in 1962. Inspired by some work with polio patients in 1962-3 she spent 1964-1965 at the Cardiovascular Research Institute, (Chief Dr Julius Comroe) University of California, in San Francisco training to be a respiratory physiologist. From 1966-1968 she set up a Respiratory Laboratory at Royal Prince Alfred Hospital (RPAH) in Sydney. After travelling through India and overland to London in 1969 she worked at the Royal Brompton Hospital with Dr Simon Godfrey 1970-1972. She received her PhD (Lond) for studies in Exercise-induced bronchoconstriction (EIB). She returned to Sydney and RPAH in 1973. In 1979 she reported that severe EIB could be prevented by inhaling warm humid air, a finding consistent with the stimulus to EIB being at the airway surface. In 1982 she proposed that it was an increase in osmolarity of the airway surface liquid arising from evaporative water loss that was the primary stimulus for EIB. She developed the hypertonic saline wet aerosol challenge and compared the responses to exercise. In 1990 she was awarded a DSc (Lond) for her publications. From 1994 together with John Brannan and Kim Chan she developed, for inhalation, a dry powder of mannitol for identifying bronchial hyperresponsiveness consistent with airway inflammation, asthma and EIB. They demonstrated that mannitol causes release of mast cell mediators and that this release is inhibited by premedication with sodium cromoglycate (Intal) or beta2 agonists, drugs used prophylactically to prevent EIB. They demonstrated that mannitol could be used clinically to monitor both the resolution of bronchial hyperresponsiveness with inhaled cortico steroids and its return following withdrawal of treatment. The mannitol test was commercialised by Pharmaxis Ltd in 2006. Her research was funded by NHMRC for >20 years. In 2012 she was awarded an honorary MD from the University of Uppsala, Sweden for her work in EIB.

Primary Affiliation: University of Sydney Faculty of Medicine and Health - Sydney, NSW , Australia

Specialties:

Additional Specialties:


View Dr Sandra D Anderson’s Resume / CV

Education

Jan 2012
University of Uppsala
MD h.c.
Honorary
Sep 2011
Uppsala Universitet
MD (Honorary)
Medicine
May 1990
University of London
DSc
awarded on publications
Aug 1972
University of London
PhD
by thesis
Mar 1959 - Apr 1962
University of Sydney Faculty of Science
BSc
Physiology/Microbiology
Apr 1962
University of Sydney
BSc
by examination

Experience

Jan 2010 - Dec 2014
Royal Prince Alfred Hospital
Principal Hospital Scientist (part-time)
Respiratory and Sleep Medicine
Jan 1979 - Jan 2009
Royal Prince Alfred Hospital
Principal Hospital Scientist
Respiratory Medicine
Jan 1973 - Jan 1979
Royal Prince Alfred Hospital
Senior Scientific Officer
Respiratory Medicine
Jul 1972 - Dec 1972
University of London
Lecturer
Institute of Diseases of the Chest (Pediatrics)
Jan 1970 - Jun 1972
University of London
Research Assistant/Assistant Lecturer
Institute of Diseases of the Chest (Pediatrics)
Jun 1966 - Dec 1968
Royal Prince Alfred Hospital
Scientific Officer
Respiratory Medicine
Dec 1966
Scientific Officer RPA Hospital Sydney
Respiratory Lab
left December 1968
Dec 1963 - Oct 1965
University of California
Post Graduate Research Chemist
Cardiovascular Research Institute
Dec 1963
Post Graduate Research Chemist San Francisco Uni California
Respiratory Lab
left October 1965
Dec 1963
Post Graduate Chemist Uni of Californi SF
Respiratory Lab
left October 1965
Mar 1962 - Oct 1963
Prince Henry Hospital
Scientific Officer
Cardiology
Research Scientist Brompton Hospi London
Research
left December 1972
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Publications

88Publications

1574Reads

17Profile Views

7PubMed Central Citations

Repurposing drugs as inhaled therapies in asthma.

Adv Drug Deliv Rev 2018 08 12;133:19-33. Epub 2018 Jun 12.

Clinical Professor, Central Clinical School, Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2018.06.006DOI Listing
August 2018
55 Reads
15.040 Impact Factor

Repurposing excipients as active inhalation agents: The mannitol story.

Adv Drug Deliv Rev 2018 08 5;133:45-56. Epub 2018 Apr 5.

Pharmaceutics, Pharmacology and Pharmaceutical Sciences, University of Sydney, Sydney, NSW 2006, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2018.04.003DOI Listing
August 2018
47 Reads
15.040 Impact Factor

Mechanisms and Biomarkers of Exercise-Induced Bronchoconstriction.

Immunol Allergy Clin North Am 2018 05;38(2):165-182

Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Center for Lung Biology, University of Washington, Box 358052, 850 Republican Street, Seattle, WA 98109-4714, USA.

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http://dx.doi.org/10.1016/j.iac.2018.01.008DOI Listing
May 2018
16 Reads
2.220 Impact Factor

'Indirect' challenges from science to clinical practice.

Eur Clin Respir J 2016 22;3:31096. Epub 2016 Feb 22.

Sydney Medical School, Central Clinical School, University of Sydney, Sydney, NSW, Australia;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764958PMC
http://dx.doi.org/10.3402/ecrj.v3.31096DOI Listing
February 2016
4 Reads
1 Citation

An Apparatus to Deliver Mannitol Powder for Bronchial Provocation in Children Under Six Years Old.

J Aerosol Med Pulm Drug Deliv 2015 Dec 6;28(6):452-61. Epub 2015 Apr 6.

1 Advanced Drug Delivery Group, Faculty of Pharmacy, The University of Sydney , Sydney, New South Wales, Australia .

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http://dx.doi.org/10.1089/jamp.2015.1208DOI Listing
December 2015
34 Reads
2.400 Impact Factor

Urinary excretion of lipid mediators in response to repeated eucapnic voluntary hyperpnea in asthmatic subjects.

J Appl Physiol (1985) 2015 Aug 25;119(3):272-9. Epub 2015 Jun 25.

Lung and Allergy Research, Department of Medicine, Karolinska University Hospital Huddinge, Karolinska Institutet, Stockholm, Sweden; The Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden;

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http://jap.physiology.org/content/jap/119/3/272.full.pdf
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http://jap.physiology.org/lookup/doi/10.1152/japplphysiol.00
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http://dx.doi.org/10.1152/japplphysiol.00301.2015DOI Listing
August 2015
28 Reads
3 Citations

Air quality and temperature effects on exercise-induced bronchoconstriction.

Compr Physiol 2015 Apr;5(2):579-610

Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Canada.

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http://dx.doi.org/10.1002/cphy.c130013DOI Listing
April 2015
6 Reads
3 Citations
1.685 Impact Factor

A World Allergy Organization international survey on physical activity as a treatment option for asthma and allergies.

World Allergy Organ J 2014 27;7(1):34. Epub 2014 Nov 27.

Institute of Translational Pharmacology, National research Council, Rome, Italy ; Department of Internal Medicine, Second University of Naples, Naples, Italy.

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http://dx.doi.org/10.1186/1939-4551-7-34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363188PMC
April 2015
23 Reads

Exercise-induced bronchoconstriction.

Ann Am Thorac Soc 2014 Dec;11(10):1651-2

1 Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California San Francisco, San Francisco, California.

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http://dx.doi.org/10.1513/AnnalsATS.201409-427OTDOI Listing
December 2014
42 Reads

Urinary CC16 after challenge with dry air hyperpnoea and mannitol in recreational summer athletes.

Respir Med 2013 Dec 2;107(12):1837-44. Epub 2013 Oct 2.

Centre for Sports Medicine and Human Performance, Brunel University, UB8 3PH Uxbridge, Middlesex, UK. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2013.09.020DOI Listing
December 2013
30 Reads
3.090 Impact Factor

Refractoriness to exercise challenge: a review of the mechanisms old and new.

Immunol Allergy Clin North Am 2013 Aug 27;33(3):329-45, viii. Epub 2013 Mar 27.

Lung and Allergy Research, Division of Respiratory Medicine and Allergy, Department of Medicine, Karolinska University Hospital Huddinge, Karolinska Institutet, M53, 14186 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.iac.2013.02.004DOI Listing
August 2013
9 Reads
2.220 Impact Factor

Pathogenesis of exercise-induced bronchoconstriction.

Immunol Allergy Clin North Am 2013 Aug 4;33(3):299-312, vii. Epub 2013 Apr 4.

Centre for Sports Medicine & Human Performance, Brunel University, Uxbridge, Middlesex UB8 3PH, UK.

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http://dx.doi.org/10.1016/j.iac.2013.02.002DOI Listing
August 2013
23 Reads
2.220 Impact Factor

The effects of mannitol on the transport of ciprofloxacin across respiratory epithelia.

Mol Pharm 2013 Aug 11;10(8):2915-24. Epub 2013 Jul 11.

Respiratory Technology, Woolcock Institute of Medical Research and Discipline of Pharmacology, Sydney Medical School, The University of Sydney, NSW 2037, Australia.

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http://dx.doi.org/10.1021/mp400030nDOI Listing
August 2013
22 Reads
4.384 Impact Factor

Mannitol test results in asthmatic adults receiving inhaled corticosteroids.

J Allergy Clin Immunol 2013 Mar 6;131(3):906-7. Epub 2012 Oct 6.

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http://dx.doi.org/10.1016/j.jaci.2012.08.028DOI Listing
March 2013
12 Reads
11.480 Impact Factor

The prevention of exercise-induced bronchoconstriction: what are the options?

Expert Rev Respir Med 2012 Aug;6(4):355-7

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http://dx.doi.org/10.1586/ers.12.33DOI Listing
August 2012
5 Reads

Assessment and prevention of exercise-induced bronchoconstriction.

Br J Sports Med 2012 May 12;46(6):391-6. Epub 2012 Jan 12.

Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

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http://dx.doi.org/10.1136/bjsports-2011-090810DOI Listing
May 2012
26 Reads
5.030 Impact Factor

Airway injury during high-level exercise.

Br J Sports Med 2012 May 12;46(6):385-90. Epub 2012 Jan 12.

Centre for Sports Medicine & Human Performance, Brunel University, Uxbridge, UK.

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http://dx.doi.org/10.1136/bjsports-2011-090819DOI Listing
May 2012
2 Reads
5.030 Impact Factor

Exercise-induced bronchoconstriction in the 21st century.

J Am Osteopath Assoc 2011 Nov;111(11 Suppl 7):S3-10

Department of Respiratory and Sleep Medicine at Royal Prince Alfred Hospital in Camperdown, New South Wales, Australia.

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November 2011
1 Read

The occurrence of refractoriness and mast cell mediator release following mannitol-induced bronchoconstriction.

J Appl Physiol (1985) 2011 Apr 20;110(4):1029-35. Epub 2011 Jan 20.

The Unit for Experimental Asthma and Allergy Research, Division of Physiology, The National Institute of EnvironmentalMedicine, Sweden.

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http://dx.doi.org/10.1152/japplphysiol.00978.2010DOI Listing
April 2011
9 Reads

Bronchial provocation testing: the future.

Curr Opin Allergy Clin Immunol 2011 Feb;11(1):46-52

Department of Respiratory & Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

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http://dx.doi.org/10.1097/ACI.0b013e3283423183DOI Listing
February 2011
8 Reads

Sodium cromoglycate and eformoterol attenuate sensitivity and reactivity to inhaled mannitol in subjects with bronchiectasis.

Respirology 2011 Jan;16(1):161-6

Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

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http://dx.doi.org/10.1111/j.1440-1843.2010.01894.xDOI Listing
January 2011
18 Reads
3.500 Impact Factor

Beneficial effect of inhaled mannitol and cough in asthmatics with mucociliary dysfunction.

Respir Med 2010 Nov 23;104(11):1645-53. Epub 2010 Jun 23.

Departments of Respiratory & Sleep Medicine, 11 West Royal Prince Hospital, Camperdown, Sydney, NSW, Australia.

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http://dx.doi.org/10.1016/j.rmed.2010.05.019DOI Listing
November 2010
5 Reads
3.090 Impact Factor

Effect of sodium cromoglycate on mast cell mediators during hyperpnea in athletes.

Med Sci Sports Exerc 2010 Oct;42(10):1853-60

Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

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http://dx.doi.org/10.1249/MSS.0b013e3181da4f7dDOI Listing
October 2010
6 Reads
3.983 Impact Factor

Airway hyperresponsiveness to methacholine, adenosine 5-monophosphate, mannitol, eucapnic voluntary hyperpnoea and field exercise challenge in elite cross-country skiers.

Br J Sports Med 2010 Sep 10;44(11):827-32. Epub 2010 May 10.

Department of Lung Medicine, St Olavs Hospital, University Hospital of Trondheim, N-7006 Trondheim, Norway.

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http://dx.doi.org/10.1136/bjsm.2009.071043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938888PMC
September 2010
7 Reads
5.030 Impact Factor

Indirect challenge tests: Airway hyperresponsiveness in asthma: its measurement and clinical significance.

Chest 2010 Aug;138(2 Suppl):25S-30S

Royal Prince Alfred Hospital, Department of Respiratory and Sleep Medicine, Sydney Medical School, University of Sydney, Camperdown, NSW, Australia.

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http://dx.doi.org/10.1378/chest.10-0116DOI Listing
August 2010
4 Reads
7.483 Impact Factor

Sodium cromoglycate alone and in combination with montelukast on the airway response to mannitol in asthmatic subjects.

J Asthma 2010 May;47(4):429-33

Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

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http://dx.doi.org/10.3109/02770900903584043DOI Listing
May 2010
6 Reads
1.830 Impact Factor

Inhaled mannitol improves the hydration and surface properties of sputum in patients with cystic fibrosis.

Chest 2010 Apr 31;137(4):861-8. Epub 2009 Oct 31.

Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, 11 West, Missenden Rd, Camperdown, Sydney, NSW 2050, Australia.

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http://dx.doi.org/10.1378/chest.09-2017DOI Listing
April 2010
16 Reads
7.483 Impact Factor

Effect of mannitol and repetitive coughing on the sputum properties in bronchiectasis.

Respir Med 2010 Mar 14;104(3):371-7. Epub 2009 Nov 14.

Department of Respiratory & Sleep Medicine, Royal Prince Alfred Hospital, 11 West, Missenden Road, Camperdown, Sydney, NSW 2050, Australia.

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http://dx.doi.org/10.1016/j.rmed.2009.10.021DOI Listing
March 2010
15 Reads
3.090 Impact Factor

Acute effects of beclomethasone on hyperpnea-induced bronchoconstriction.

Med Sci Sports Exerc 2010 Feb;42(2):273-80

Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, NSW Australia.

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http://dx.doi.org/10.1249/MSS.0b013e3181b541b1DOI Listing
February 2010
10 Reads
3.983 Impact Factor

Inhaled mannitol as a test for bronchial hyper-responsiveness.

Expert Rev Respir Med 2009 Oct;3(5):457-68

Department of Respiratory and Sleep Medicine, 11 West, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2050, Australia.

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http://dx.doi.org/10.1586/ers.09.38DOI Listing
October 2009
2 Reads

Comparison of mannitol and methacholine to predict exercise-induced bronchoconstriction and a clinical diagnosis of asthma.

Respir Res 2009 Jan 23;10. Epub 2009 Jan 23.

Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2050, Australia.

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http://dx.doi.org/10.1186/1465-9921-10-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644668PMC
January 2009
21 Reads

Pulmonary gas exchange response to exercise- and mannitol-induced bronchoconstriction in mild asthma.

J Appl Physiol (1985) 2008 Nov 28;105(5):1477-85. Epub 2008 Aug 28.

Servei de Pneumologia, Institut del Tórax, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Ciber Enfermedades Respiratorias, Universitat de Barcelona, Spain.

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http://dx.doi.org/10.1152/japplphysiol.00108.2008DOI Listing
November 2008
20 Reads

Airway responses to eucapnic hyperpnea, exercise, and methacholine in elite swimmers.

Med Sci Sports Exerc 2008 Sep;40(9):1567-72

Respiratory and Allergy Research Unit, Department of Respiratory Medicine L, Bispebjerg Hospital, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1249/MSS.0b013e31875719aDOI Listing
September 2008
7 Reads
3.983 Impact Factor

Airway injury as a mechanism for exercise-induced bronchoconstriction in elite athletes.

J Allergy Clin Immunol 2008 Aug 12;122(2):225-35; quiz 236-7. Epub 2008 Jun 12.

Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales 2050, Australia.

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http://dx.doi.org/10.1016/j.jaci.2008.05.001DOI Listing
August 2008
6 Reads
11.480 Impact Factor

Asthma and the elite athlete: summary of the International Olympic Committee's consensus conference, Lausanne, Switzerland, January 22-24, 2008.

J Allergy Clin Immunol 2008 Aug;122(2):254-60, 260.e1-7

School of Sports Science, Exercise and Health, Faculty of Life Sciences, University of Western Australia, Crawley, Australia.

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http://dx.doi.org/10.1016/j.jaci.2008.07.003DOI Listing
August 2008
6 Reads
11.480 Impact Factor

Inhaled mannitol improves lung function in cystic fibrosis.

Chest 2008 Jun 13;133(6):1388-1396. Epub 2008 Mar 13.

Department of Clinical Research, Pharmaxis Ltd, Frenchs Forest, NSW, Australia.

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http://dx.doi.org/10.1378/chest.07-2294DOI Listing
June 2008
31 Reads
7.483 Impact Factor

Provocative challenges to help diagnose and monitor asthma: exercise, methacholine, adenosine, and mannitol.

Curr Opin Pulm Med 2008 Jan;14(1):39-45

Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

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http://dx.doi.org/10.1097/MCP.0b013e3282f197f6DOI Listing
January 2008
22 Reads
2.760 Impact Factor

Inhaled mannitol changes the sputum properties in asthmatics with mucus hypersecretion.

Respirology 2007 Sep;12(5):683-91

Department of Respiratory Medicine Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1111/j.1440-1843.2007.01107.xDOI Listing
September 2007
19 Reads
3.500 Impact Factor

Monitoring asthma therapy using indirect bronchial provocation tests.

Clin Respir J 2007 Jul;1(1):3-15

Firestone Institute for Respiratory Health, McMaster University, Hamilton, Ontario, Canada L8N 4A6.

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http://dx.doi.org/10.1111/j.1752-699X.2007.00004.xDOI Listing
July 2007
23 Reads
2.200 Impact Factor

Airway reactivity to inhaled mannitol in cigarette smokers: a longitudinal study.

Respir Med 2007 Jul 26;101(7):1470-6. Epub 2007 Feb 26.

Pulmonary Medicine and Respiratory Cell Research and Hospital Pharmacy, University Hospital Basel, Switzerland.

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http://dx.doi.org/10.1016/j.rmed.2007.01.008DOI Listing
July 2007
89 Reads
3.090 Impact Factor

Beta2-agonists and exercise-induced asthma.

Clin Rev Allergy Immunol 2006 Oct-Dec;31(2-3):163-80

Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, Australia.

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http://dx.doi.org/10.1385/CRIAI:31:2:163DOI Listing
February 2007
24 Reads
5.463 Impact Factor

Hyperosmolar agents and clearance of mucus in the diseased airway.

J Aerosol Med 2006 ;19(1):100-9

Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW, Australia.

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http://dx.doi.org/10.1089/jam.2006.19.100DOI Listing
May 2006
6 Reads

Bronchial challenges in athletes applying to inhale a beta2-agonist at the 2004 Summer Olympics.

J Allergy Clin Immunol 2006 Apr 3;117(4):767-73. Epub 2006 Mar 3.

Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.

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http://dx.doi.org/10.1016/j.jaci.2005.12.1355DOI Listing
April 2006
5 Reads
11.480 Impact Factor

How does exercise cause asthma attacks?

Curr Opin Allergy Clin Immunol 2006 Feb;6(1):37-42

Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.

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http://dx.doi.org/10.1097/01.all.0000199797.02423.78DOI Listing
February 2006
21 Reads

Dissociation in the effect of nedocromil on mannitol-induced cough or bronchoconstriction in asthmatic subjects.

Respirology 2005 Sep;10(4):442-8

Department of Respiratory Medicine, Kuopio University Hospital, Kuopio, Finland.

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http://dx.doi.org/10.1111/j.1440-1843.2005.00724.xDOI Listing
September 2005
50 Reads
3.500 Impact Factor

Mucociliary clearance in patients with chronic asthma: effects of beta agonists.

Respirology 2005 Sep;10(4):426-35

Department of Respiratory Medicine, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1111/j.1440-1843.2005.00738.xDOI Listing
September 2005
28 Reads
3.500 Impact Factor

Prediction of treatment-response to inhaled corticosteroids by mannitol-challenge test in COPD. A proof of concept.

Pulm Pharmacol Ther 2005 21;18(2):83-8. Epub 2004 Dec 21.

Pneumology, Department of Internal Medicine, University Hospital, Petersgraben 4, Basel CH-4031, Switzerland.

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http://dx.doi.org/10.1016/j.pupt.2004.10.005DOI Listing
May 2005
20 Reads
2.940 Impact Factor

Questionnaire responses that predict airway response to hypertonic saline.

Respiration 2005 Jan-Feb;72(1):52-60

Woolcock Institute of Medical Research, University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1159/000083401DOI Listing
May 2005
20 Reads
2.593 Impact Factor

Single-dose agents in the prevention of exercise-induced asthma: a descriptive review.

Treat Respir Med 2004 ;3(6):365-79

Department of Respiratory Medicine, 11 West, Royal Prince Alfred Hospital, Missenden Road, Camperdown, New South Wales 2050, Australia.

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http://dx.doi.org/10.2165/00151829-200403060-00004DOI Listing
April 2005
4 Reads

Exercise-induced bronchoconstriction: pathogenesis.

Curr Allergy Asthma Rep 2005 Mar;5(2):116-22

Department of Respiratory Medicine, 11 West, Royal Prince Alfred Hospital, Missenden Road, Camperdown NSW 2050, Australia.

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http://dx.doi.org/10.1007/s11882-005-0084-yDOI Listing
March 2005
15 Reads
2.770 Impact Factor

Inhaled mannitol for the treatment of mucociliary dysfunction in patients with bronchiectasis: effect on lung function, health status and sputum.

Respirology 2005 Jan;10(1):46-56

Department of Respiratory Medicine, Royal Prince Alfred Hospital, Sydney, NSW, Australia.

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http://dx.doi.org/10.1111/j.1440-1843.2005.00659.xDOI Listing
January 2005
10 Reads
3.500 Impact Factor

Long-acting beta 2-adrenoceptor agonists and exercise-induced asthma: lessons to guide us in the future.

Paediatr Drugs 2004 ;6(3):161-75

Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW, Australia.

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http://dx.doi.org/10.2165/00148581-200406030-00003DOI Listing
December 2004
23 Reads
1.721 Impact Factor

Coughing during mannitol challenge is associated with asthma.

Chest 2004 Jun;125(6):1985-92

Department of Respiratory Medicine (Drs. Koskela and Hyvärinen), Kuopio University Hospital, Kuopio, Finland.

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http://dx.doi.org/10.1378/chest.125.6.1985DOI Listing
June 2004
15 Reads
7.483 Impact Factor

Field exercise vs laboratory eucapnic voluntary hyperventilation to identify airway hyperresponsiveness in elite cold weather athletes.

Chest 2004 Mar;125(3):909-15

Marywood University, Scranton, PA 18509-4742, USA.

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http://dx.doi.org/10.1378/chest.125.3.909DOI Listing
March 2004
33 Reads
7.483 Impact Factor

Responsiveness to three bronchial provocation tests in patients with asthma.

Chest 2003 Dec;124(6):2171-7

Department of Respiratory Medicine, Kuopio University Hospital, PL 1777, 70210 Kuopio, Finland.

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http://dx.doi.org/10.1378/chest.124.6.2171DOI Listing
December 2003
28 Reads
7.483 Impact Factor

Sensitivity and validity of three bronchial provocation tests to demonstrate the effect of inhaled corticosteroids in asthma.

Chest 2003 Oct;124(4):1341-9

Department of Respiratory Medicine, Kuopio University Hospital, Kuopio, Finland.

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http://dx.doi.org/10.1378/chest.124.4.1341DOI Listing
October 2003
29 Reads
7.483 Impact Factor

Airway surface fluid desiccation during isocapnic hyperpnea.

J Appl Physiol (1985) 2003 Jun;94(6):2545-6; author reply 2546-7

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http://dx.doi.org/10.1152/japplphysiol.00018.2003DOI Listing
June 2003
4 Reads

The effects of histamine and leukotriene receptor antagonism on nasal mannitol challenge in allergic rhinitis.

Br J Clin Pharmacol 2003 Jun;55(6):639-42

Asthma & Allergy Research Group, Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884269PMC
http://dx.doi.org/10.1046/j.1365-2125.2003.01807.xDOI Listing
June 2003
2 Reads
3.880 Impact Factor

Mannitol as a challenge test to identify exercise-induced bronchoconstriction in elite athletes.

Am J Respir Crit Care Med 2003 Feb 27;167(4):534-7. Epub 2002 Nov 27.

Department of Allergy, Alfred Hospital and Monash University, Prahran, Victoria, Australia.

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http://dx.doi.org/10.1164/rccm.200208-916OCDOI Listing
February 2003
21 Reads
13.000 Impact Factor

Methods for "indirect" challenge tests including exercise, eucapnic voluntary hyperpnea, and hypertonic aerosols.

Clin Rev Allergy Immunol 2003 Feb;24(1):27-54

Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, NSW Australia.

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http://dx.doi.org/10.1385/CRIAI:24:1:27DOI Listing
February 2003
21 Reads
5.463 Impact Factor

Responses to bronchial challenge submitted for approval to use inhaled beta2-agonists before an event at the 2002 Winter Olympics.

J Allergy Clin Immunol 2003 Jan;111(1):45-50

Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.

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http://dx.doi.org/10.1067/mai.2003.1DOI Listing
January 2003
18 Reads
11.480 Impact Factor

Osmotic stimuli increase clearance of mucus in patients with mucociliary dysfunction.

J Aerosol Med 2002 ;15(3):331-41

Department of Respiratory Medicine, Royal Prince Alfred Hospital, Sydney, Australia.

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http://dx.doi.org/10.1089/089426802760292681DOI Listing
November 2002
21 Reads

Exercise in elite summer athletes: Challenges for diagnosis.

J Allergy Clin Immunol 2002 Sep;110(3):374-80

Department of Allergy, Asthma and Clinical Immunology, Alfred Hospital and Monash University, Prahran, Australia.

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http://dx.doi.org/10.1067/mai.2002.127784DOI Listing
September 2002
9 Reads
11.480 Impact Factor

Exercise-induced asthma in children: a marker of airway inflammation.

Med J Aust 2002 09;177(S6):S61-3

Department of Respiratory Medicine, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW.

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September 2002
18 Reads
4.090 Impact Factor

Bronchial provocation tests: the rationale for using inhaled mannitol as a test for airway hyperresponsiveness.

Swiss Med Wkly 2002 Apr;132(13-14):151-8

Respiratory Medicine, Department of Internal Medicine, University Hospital, Basel, Switzerland.

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http://dx.doi.org/2002/13/smw-09850DOI Listing
April 2002
12 Reads

Budesonide reduces sensitivity and reactivity to inhaled mannitol in asthmatic subjects.

Respirology 2002 Mar;7(1):37-44

Department of Respiratory Medicine, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.

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http://dx.doi.org/10.1046/j.1440-1843.2002.00357.xDOI Listing
March 2002
14 Reads
3.500 Impact Factor

The use of the treadmill for assessing exercise-induced asthma and the effect of varying the severity and duration of exercise.

Pediatrics 1975 Nov;56(5 pt-2 suppl):893-8

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November 1975
1 Read
5.473 Impact Factor

Exercise-induced asthma.

Br J Dis Chest 1975 Jan;69(1):1-39

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http://dx.doi.org/10.1016/0007-0971(75)90053-4DOI Listing
January 1975
2 Reads

Problems of interpreting exercise-induced asthma.

J Allergy Clin Immunol 1973 Oct;52(4):199-209

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http://dx.doi.org/10.1016/0091-6749(73)90058-4DOI Listing
October 1973
2 Reads
11.476 Impact Factor

Standardization of exercise tests in asthmatic children.

Arch Dis Child 1972 Dec;47(256):882-9

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1648423PMC
http://dx.doi.org/10.1136/adc.47.256.882DOI Listing
December 1972
2 Reads
2.899 Impact Factor

Metabolic cost of treadmill exercise in children.

J Appl Physiol 1972 Nov;33(5):696-8

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http://dx.doi.org/10.1152/jappl.1972.33.5.696DOI Listing
November 1972
2 Reads

Exercise asthma.

Lancet 1972 Mar;1(7749):533

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http://dx.doi.org/10.1016/s0140-6736(72)90195-xDOI Listing
March 1972
1 Read
45.217 Impact Factor

Cardio-respiratory response to treadmill exercise in normal children.

Clin Sci 1971 May;40(5):433-42

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http://dx.doi.org/10.1042/cs0400433DOI Listing
May 1971
3 Reads

Transfer factor for CO during exercise in children.

Thorax 1971 Jan;26(1):51-4

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC472234PMC
http://dx.doi.org/10.1136/thx.26.1.51DOI Listing
January 1971
2 Reads
8.290 Impact Factor

PULMONARY-FUNCTION ABNORMALITIES AFTER LYMPHANGIOGRAPHY.

N Engl J Med 1965 Sep;273:519-24

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http://dx.doi.org/10.1056/NEJM196509022731003DOI Listing
September 1965
2 Reads
55.873 Impact Factor