Publications by authors named "Samuel Weiss"

70Publications

Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma.

Cell 2020 Jun 22;181(6):1329-1345.e24. Epub 2020 May 22.

The Arthur and Sonia Labatt Brain Tumor Research Center, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON M5G 1L7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.04.047DOI Listing
June 2020

EGFR blockade in GBM brain tumor stem cells synergizes with JAK2/STAT3 pathway inhibition to abrogate compensatory mechanisms in vitro and in vivo.

Neurooncol Adv 2020 Jan-Dec;2(1):vdaa020. Epub 2020 Feb 18.

Hotchkiss Brain Institute and Arnie Charbonneau Cancer Institute, Department of Cell Biology and Anatomy, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1093/noajnl/vdaa020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086303PMC
February 2020

A Case of Serum Sickness-Like Reaction in an Adult Treated with Omalizumab.

Mil Med 2020 06;185(5-6):e912-e913

Allergy/Immunology, Wilford Hall Ambulatory Surgical Center, 1100 Wilford Hall Loop, Lackland AFB, TX 78236.

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http://dx.doi.org/10.1093/milmed/usz357DOI Listing
June 2020

SLUG Directs the Precursor State of Human Brain Tumor Stem Cells.

Cancers (Basel) 2019 Oct 24;11(11). Epub 2019 Oct 24.

Hotchkiss Brain Institute, Department of Cell Biology and Anatomy, Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.

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http://dx.doi.org/10.3390/cancers11111635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895861PMC
October 2019

A Neuroethics Backbone for the Evolving Canadian Brain Research Strategy.

Neuron 2019 02;101(3):370-374

Departments of Ecology and Evolutionary Biology & Cell and Systems Biology, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.neuron.2018.12.021DOI Listing
February 2019

Isolation and Culture of Glioblastoma Brain Tumor Stem Cells.

Methods Mol Biol 2019 ;1869:11-21

Department of Cell Biology and Anatomy, Faculty of Medicine, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.1007/978-1-4939-8805-1_2DOI Listing
May 2019

Live-Cell Imaging Assays to Study Glioblastoma Brain Tumor Stem Cell Migration and Invasion.

J Vis Exp 2018 08 29(138). Epub 2018 Aug 29.

Hotchkiss Brain Institute, Department of Cell Biology and Anatomy, Cumming School of Medicine, University of Calgary;

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http://dx.doi.org/10.3791/58152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231945PMC
August 2018

Disulfiram when Combined with Copper Enhances the Therapeutic Effects of Temozolomide for the Treatment of Glioblastoma.

Clin Cancer Res 2016 08 22;22(15):3860-75. Epub 2016 Mar 22.

Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada. Clark H. Smith Brain Tumour Centre, University of Calgary, Calgary, Alberta, Canada. Department of Oncology, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-1798DOI Listing
August 2016

Precursor States of Brain Tumor Initiating Cell Lines Are Predictive of Survival in Xenografts and Associated with Glioblastoma Subtypes.

Stem Cell Reports 2015 Jul 18;5(1):1-9. Epub 2015 Jun 18.

Hotchkiss Brain Institute, Department of Cell Biology and Anatomy, University of Calgary, Calgary, AB T2N 4N1, Canada; Southern Alberta Cancer Research Institute, University of Calgary, Calgary, AB T2N 4N1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2015.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618251PMC
July 2015

IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.

Cancer Res 2015 Aug 4;75(15):2999-3009. Epub 2015 Jun 4.

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-0840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526330PMC
August 2015

Prolactin in combination with interferon-β reduces disease severity in an animal model of multiple sclerosis.

J Neuroinflammation 2015 Mar 19;12:55. Epub 2015 Mar 19.

Hotchkiss Brain Institute and the Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada.

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http://dx.doi.org/10.1186/s12974-015-0278-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367923PMC
March 2015

Dual mTORC1/2 blockade inhibits glioblastoma brain tumor initiating cells in vitro and in vivo and synergizes with temozolomide to increase orthotopic xenograft survival.

Clin Cancer Res 2014 Nov 14;20(22):5756-67. Epub 2014 Oct 14.

Hotchkiss Brain Institute, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada. Department of Cell Biology and Anatomy, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada. Clark Smith Brain Tumour Research Centre, Southern Alberta Cancer Research Institute, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-13-3389DOI Listing
November 2014

Novel MSH6 mutations in treatment-naïve glioblastoma and anaplastic oligodendroglioma contribute to temozolomide resistance independently of MGMT promoter methylation.

Clin Cancer Res 2014 Sep 30;20(18):4894-903. Epub 2014 Jul 30.

Hotchkiss Brain Institute, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada. Department of Cell Biology and Anatomy, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada. Clark Smith Brain Tumor Research Centre, Southern Alberta Cancer Research Institute, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-13-1856DOI Listing
September 2014

Lactate dehydrogenase A silencing in IDH mutant gliomas.

Neuro Oncol 2014 May 22;16(5):686-95. Epub 2013 Dec 22.

Department of Clinical Neurosciences, Foothills Hospital, Calgary, Alberta, Canada (C.C., M.D.B., M.A.-N., J.A.C., S.W., J.G.C.); Department of Cell Biology and Anatomy, Health Research Innovation Centre, Calgary, Alberta, Canada (O.D.S., S.W., H.A.L.); Department of Pathology & Laboratory Medicine, Foothills Hospital, Calgary, Alberta, Canada (J.A.C.); Southern Alberta Cancer Research Institute, Health Research Innovation Centre, Calgary, Alberta, Canada (C.C., M.D.B., M.A.-N., J.A.C., S.W., H.A.L., J.G.C.); Hotchkiss Brain Institute, Health Research Innovation Centre, Calgary, Alberta, Canada (O.D.S., S.W., H.A.L.); Department of Radiology and Biomedical Imaging, San Francisco, California (M.M.C., S.M.R.); Brain Tumor Research Center, Department of Neurological Surgery, San Francisco, California (R.O.P).

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http://dx.doi.org/10.1093/neuonc/not243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984548PMC
May 2014

Therapeutic activation of macrophages and microglia to suppress brain tumor-initiating cells.

Nat Neurosci 2014 Jan 8;17(1):46-55. Epub 2013 Dec 8.

1] Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada. [2] Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1038/nn.3597DOI Listing
January 2014

Culturing fetal precursor cells using free floating serum-free conditions.

Methods Mol Biol 2013 ;1059:3-12

Department of Cell Biology and Anatomy, Faculty of Medicine, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.1007/978-1-62703-574-3_1DOI Listing
February 2014

Bi-parental care contributes to sexually dimorphic neural cell genesis in the adult mammalian brain.

PLoS One 2013 1;8(5):e62701. Epub 2013 May 1.

Department of Cell Biology & Anatomy, Faculty of Medicine, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062701PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641101PMC
November 2013

Prolactin in multiple sclerosis.

Mult Scler 2013 Jan 29;19(1):15-23. Epub 2012 Aug 29.

Multiple Sclerosis Program, Department of Clinical Neurosciences, University of Calgary, Canada.

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http://dx.doi.org/10.1177/1352458512458555DOI Listing
January 2013

Adult periventricular neural stem cells: outstanding progress and outstanding issues.

Dev Neurobiol 2012 Jul;72(7):972-89

Department of Cell Biology and Anatomy, Hotchkiss Brain Institute, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1002/dneu.22029DOI Listing
July 2012

Platelet-derived growth factor-responsive neural precursors give rise to myelinating oligodendrocytes after transplantation into the spinal cords of contused rats and dysmyelinated mice.

Glia 2011 Dec 23;59(12):1891-910. Epub 2011 Aug 23.

International Collaboration on Repair Discoveries, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/glia.21232DOI Listing
December 2011

Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation.

Nature 2012 Feb 15;483(7390):484-8. Epub 2012 Feb 15.

Biocenter Oulu, Department of Medical Biochemistry and Molecular Biology, Oulu Center for Cell-Matrix Research, University of Oulu, FIN-90014 Oulu, Finland.

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http://www.nature.com/articles/nature10898
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http://dx.doi.org/10.1038/nature10898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656605PMC
February 2012

PDGFRα expression distinguishes GFAP-expressing neural stem cells from PDGF-responsive neural precursors in the adult periventricular area.

J Neurosci 2011 Jun;31(26):9503-12

Hotchkiss Brain Institute and Department of Cell Biology and Anatomy, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.1531-11.2
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http://dx.doi.org/10.1523/JNEUROSCI.1531-11.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6623177PMC
June 2011

Paternal recognition of adult offspring mediated by newly generated CNS neurons.

Nat Neurosci 2010 Jun 9;13(6):753-8. Epub 2010 May 9.

Hotchkiss Brain Institute, Department of Cell Biology & Anatomy, University of Calgary, Faculty of Medicine, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1038/nn.2550DOI Listing
June 2010

Sensitivity to temozolomide in brain tumor initiating cells.

Neuro Oncol 2010 Jul 13;12(7):756-60. Epub 2010 Apr 13.

Department of Clinical Neurosciences, Foothills Medical Centre, 1403 29th St NW, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1093/neuonc/noq032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940656PMC
July 2010

Neurotalk: improving the communication of neuroscience research.

Nat Rev Neurosci 2010 01 2;11(1):61-9. Epub 2009 Dec 2.

National Core for Neuroethics, The University of British Columbia, 2211 Wesbrook Mall, Koerner S124, Vancouver, British Columbia V6T 2B5, Canada.

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http://dx.doi.org/10.1038/nrn2773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818800PMC
January 2010

Pigment epithelium-derived growth factor: modulating adult neural stem cell self-renewal.

Nat Neurosci 2009 Dec;12(12):1481-3

Department of Cell Biology and Anatomy, Hotchkiss Brain Institute, University of Calgary, Alberta, Canada.

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http://dx.doi.org/10.1038/nn1209-1481DOI Listing
December 2009

Promoting oligodendrogenesis and myelin repair using the multiple sclerosis medication glatiramer acetate.

Proc Natl Acad Sci U S A 2009 Oct 6;106(42):17992-7. Epub 2009 Oct 6.

Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta T2N 4N1, Canada.

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http://dx.doi.org/10.1073/pnas.0909607106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758287PMC
October 2009

Identity crisis for adult periventricular neural stem cells: subventricular zone astrocytes, ependymal cells or both?

Nat Rev Neurosci 2009 Feb;10(2):153-63

Hotchkiss Brain Institute, Department of Cell Biology and Anatomy, University of Calgary, Faculty of Medicine, Calgary, Alberta, T2N 4N1, Canada.

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http://www.nature.com/articles/nrn2571
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http://dx.doi.org/10.1038/nrn2571DOI Listing
February 2009

Distinctions between fetal and adult human platelet-derived growth factor-responsive neural precursors.

Ann Neurol 2008 Aug;64(2):127-42

Department of Cell Biology and Anatomy, Hotchkiss Brain Institute, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1002/ana.21421DOI Listing
August 2008

Production of neurons, astrocytes and oligodendrocytes from mammalian CNS stem cells.

Nat Protoc 2008 ;3(6):935-40

Hotchkiss Brain Institute, Department of Cell Biology and Anatomy, Faculty of Medicine, University of Calgary, Calgary, Alberta Canada.

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http://dx.doi.org/10.1038/nprot.2008.55DOI Listing
September 2008

Male pheromone-stimulated neurogenesis in the adult female brain: possible role in mating behavior.

Nat Neurosci 2007 Aug 1;10(8):1003-11. Epub 2007 Jul 1.

Hotchkiss Brain Institute, Department of Cell Biology & Anatomy, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada.

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http://www.nature.com/articles/nn1928
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http://dx.doi.org/10.1038/nn1928DOI Listing
August 2007

STAT5A/B activity is required in the developing forebrain and spinal cord.

Mol Cell Neurosci 2007 Jun 13;35(2):272-82. Epub 2007 Mar 13.

Hotchkiss Brain Institute, Faculty of Medicine, University of Calgary, HSC 2153, 3330 Hospital Drive NW, Calgary, AB, Canada T2N 4N1.

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http://dx.doi.org/10.1016/j.mcn.2007.03.001DOI Listing
June 2007

White matter plasticity and enhanced remyelination in the maternal CNS.

J Neurosci 2007 Feb;27(8):1812-23

Hotchkiss Brain Institute, Department of Cell Biology, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada T2N 4N1.

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http://dx.doi.org/10.1523/JNEUROSCI.4441-06.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673564PMC
February 2007

Growth factor-stimulated generation of new cortical tissue and functional recovery after stroke damage to the motor cortex of rats.

J Cereb Blood Flow Metab 2007 May 20;27(5):983-97. Epub 2006 Sep 20.

Department of Psychology, Canadian Centre for Behavioral Neuroscience, University of Lethbridge, Lethbridge, Alberta, Canada.

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http://dx.doi.org/10.1038/sj.jcbfm.9600402DOI Listing
May 2007

Pituitary adenylate cyclase-activating polypeptide regulates forebrain neural stem cells and neurogenesis in vitro and in vivo.

J Neurosci Res 2006 Nov;84(6):1177-86

Department of Cell Biology and Anatomy, Faculty of Medicine, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1002/jnr.21026DOI Listing
November 2006

Re: Phantom limb pain.

Authors:
Samuel A Weiss

J Pain Symptom Manage 2006 Aug;32(2):103; author reply 103

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http://dx.doi.org/10.1016/j.jpainsymman.2006.06.002DOI Listing
August 2006

Immunobiology of oligodendrocytes in multiple sclerosis.

Adv Neurol 2006 ;98:47-63

Neuroscience-Neuroimmunology Unit, DIBIT-San Raffaele Hospital, Milan, Italy.

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February 2006

CNTF/LIF/gp130 receptor complex signaling maintains a VZ precursor differentiation gradient in the developing ventral forebrain.

Development 2005 Feb 5;132(3):565-78. Epub 2005 Jan 5.

Genes and Development Research Group, Hotchkiss Brain Institute, University of Calgary Faculty of Medicine, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada.

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http://dev.biologists.org/cgi/doi/10.1242/dev.01592
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http://dx.doi.org/10.1242/dev.01592DOI Listing
February 2005

Isolation of a novel platelet-derived growth factor-responsive precursor from the embryonic ventral forebrain.

J Neurosci 2004 Dec;24(48):10888-99

Genes and Development Research Group, Department of Cell Biology and Anatomy, University of Calgary, Faculty of Medicine, Calgary, Alberta, T2N 4N1 Canada.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.3302-04.2
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http://dx.doi.org/10.1523/JNEUROSCI.3302-04.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730217PMC
December 2004

Aging results in reduced epidermal growth factor receptor signaling, diminished olfactory neurogenesis, and deficits in fine olfactory discrimination.

J Neurosci 2004 Sep;24(38):8354-65

Genes and Development Research Group, Department of Cell Biology and Anatomy, University of Calgary Faculty of Medicine, Calgary, Alberta T2N 4N1, Canada.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.2751-04.2
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http://dx.doi.org/10.1523/JNEUROSCI.2751-04.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6729689PMC
September 2004

Generation of functional radial glial cells by embryonic and adult forebrain neural stem cells.

J Neurosci 2003 Dec;23(37):11587-601

Genes & Development Research Group, University of Calgary, Faculty of Medicine, Calgary, Alberta, Canada T2N 4N1.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6740965PMC
December 2003

Characteristics of the type B tympanogram can predict the magnitude of the air-bone gap in otitis media with effusion.

Ann Otol Rhinol Laryngol 2003 May;112(5):450-4

Department of Otolaryngology-Head and Neck Surgery, Hadassah University Hospital, Jerusalem, Israel.

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http://dx.doi.org/10.1177/000348940311200512DOI Listing
May 2003

Glycoprotein 130 signaling regulates Notch1 expression and activation in the self-renewal of mammalian forebrain neural stem cells.

J Neurosci 2003 Mar;23(5):1730-41

Genes & Development Research Group, Department of Cell Biology and Anatomy, University of Calgary, Faculty of Medicine, Calgary, Alberta, Canada T2N 4N1.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741977PMC
March 2003

What can our nose tell us about possible treatments for Alzheimer's disease?

Authors:
Samuel Weiss

Can J Neurol Sci 2003 Feb;30(1)

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http://dx.doi.org/10.1017/s0317167100002341DOI Listing
February 2003

Pregnancy-stimulated neurogenesis in the adult female forebrain mediated by prolactin.

Science 2003 Jan;299(5603):117-20

Genes & Development Research Group, Department of Cell Biology and Anatomy, University of Calgary Faculty of Medicine, Calgary, Alberta, Canada T2N 4N1.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1076647
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http://dx.doi.org/10.1126/science.1076647DOI Listing
January 2003

Nitric oxide promotes intracellular calcium release from mitochondria in striatal neurons.

FASEB J 2002 Oct;16(12):1611-22

Institute for Medical Neurobiology, University of Magdeburg, Germany.

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http://dx.doi.org/10.1096/fj.02-0126comDOI Listing
October 2002

Radial glial cells as neuronal precursors: the next generation?

J Neurosci Res 2002 Sep;69(6):708-13

Genes and Development Research Group, University of Calgary Faculty of Medicine, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1002/jnr.10340DOI Listing
September 2002