Samuel C Dudley

Samuel C Dudley

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Samuel C Dudley

Samuel C Dudley

Publications by authors named "Samuel C Dudley"

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Isolevuglandin scavenger attenuates pressure overload-induced cardiac oxidative stress, cardiac hypertrophy, heart failure and lung remodeling.

Free Radic Biol Med 2019 Sep 26;141:291-298. Epub 2019 Jun 26.

Lillehei Heart Institute and Cardiovascular Division, University of Minnesota Medical School, Minneapolis, MN, 55455, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2019.06.029DOI Listing
September 2019

The role of the unfolded protein response in arrhythmias.

Channels (Austin) 2018 ;12(1):335-345

a Division of Cardiology, Department of Medicine, The Lillehei Heart Institute , University of Minnesota at Twin Cities , Minneapolis , USA.

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http://dx.doi.org/10.1080/19336950.2018.1516985DOI Listing
August 2019

Mitochondrial Ca2+ flux modulates spontaneous electrical activity in ventricular cardiomyocytes.

PLoS One 2018 12;13(7):e0200448. Epub 2018 Jul 12.

Department of Medicine, Lillehei Heart Institute, University of Minnesota, Minneapolis, MN, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0200448PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042741PMC
January 2019

Magnesium supplementation improves diabetic mitochondrial and cardiac diastolic function.

JCI Insight 2019 Jan 10;4(1). Epub 2019 Jan 10.

Division of Cardiology, Department of Medicine, the Lillehei Heart Institute, University of Minnesota at Twin Cities, Minneapolis, Minnesota.

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https://insight.jci.org/articles/view/123182
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http://dx.doi.org/10.1172/jci.insight.123182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485371PMC
January 2019

Functional cardiac Na channels are expressed in human melanoma cells.

Oncol Lett 2018 Aug 31;16(2):1689-1695. Epub 2018 May 31.

Department of Biology, Providence College, Providence, RI 02918, USA.

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http://dx.doi.org/10.3892/ol.2018.8865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036419PMC
August 2018

HuR-mediated SCN5A messenger RNA stability reduces arrhythmic risk in heart failure.

Heart Rhythm 2018 07 16;15(7):1072-1080. Epub 2018 Feb 16.

Department of Cardiology, The Warren Alpert Medical School of Brown University, Providence, Rhode Island; The Lillehei Heart Institute, University of Minnesota, Minneapolis, Minnesota. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2018.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026071PMC
July 2018

Multi-ethnic genome-wide association study for atrial fibrillation.

Authors:
Carolina Roselli Mark D Chaffin Lu-Chen Weng Stefanie Aeschbacher Gustav Ahlberg Christine M Albert Peter Almgren Alvaro Alonso Christopher D Anderson Krishna G Aragam Dan E Arking John Barnard Traci M Bartz Emelia J Benjamin Nathan A Bihlmeyer Joshua C Bis Heather L Bloom Eric Boerwinkle Erwin B Bottinger Jennifer A Brody Hugh Calkins Archie Campbell Thomas P Cappola John Carlquist Daniel I Chasman Lin Y Chen Yii-Der Ida Chen Eue-Keun Choi Seung Hoan Choi Ingrid E Christophersen Mina K Chung John W Cole David Conen James Cook Harry J Crijns Michael J Cutler Scott M Damrauer Brian R Daniels Dawood Darbar Graciela Delgado Joshua C Denny Martin Dichgans Marcus Dörr Elton A Dudink Samuel C Dudley Nada Esa Tonu Esko Markku Eskola Diane Fatkin Stephan B Felix Ian Ford Oscar H Franco Bastiaan Geelhoed Raji P Grewal Vilmundur Gudnason Xiuqing Guo Namrata Gupta Stefan Gustafsson Rebecca Gutmann Anders Hamsten Tamara B Harris Caroline Hayward Susan R Heckbert Jussi Hernesniemi Lynne J Hocking Albert Hofman Andrea R V R Horimoto Jie Huang Paul L Huang Jennifer Huffman Erik Ingelsson Esra Gucuk Ipek Kaoru Ito Jordi Jimenez-Conde Renee Johnson J Wouter Jukema Stefan Kääb Mika Kähönen Yoichiro Kamatani John P Kane Adnan Kastrati Sekar Kathiresan Petra Katschnig-Winter Maryam Kavousi Thorsten Kessler Bas L Kietselaer Paulus Kirchhof Marcus E Kleber Stacey Knight Jose E Krieger Michiaki Kubo Lenore J Launer Jari Laurikka Terho Lehtimäki Kirsten Leineweber Rozenn N Lemaitre Man Li Hong Euy Lim Henry J Lin Honghuang Lin Lars Lind Cecilia M Lindgren Marja-Liisa Lokki Barry London Ruth J F Loos Siew-Kee Low Yingchang Lu Leo-Pekka Lyytikäinen Peter W Macfarlane Patrik K Magnusson Anubha Mahajan Rainer Malik Alfredo J Mansur Gregory M Marcus Lauren Margolin Kenneth B Margulies Winfried März David D McManus Olle Melander Sanghamitra Mohanty Jay A Montgomery Michael P Morley Andrew P Morris Martina Müller-Nurasyid Andrea Natale Saman Nazarian Benjamin Neumann Christopher Newton-Cheh Maartje N Niemeijer Kjell Nikus Peter Nilsson Raymond Noordam Heidi Oellers Morten S Olesen Marju Orho-Melander Sandosh Padmanabhan Hui-Nam Pak Guillaume Paré Nancy L Pedersen Joanna Pera Alexandre Pereira David Porteous Bruce M Psaty Sara L Pulit Clive R Pullinger Daniel J Rader Lena Refsgaard Marta Ribasés Paul M Ridker Michiel Rienstra Lorenz Risch Dan M Roden Jonathan Rosand Michael A Rosenberg Natalia Rost Jerome I Rotter Samir Saba Roopinder K Sandhu Renate B Schnabel Katharina Schramm Heribert Schunkert Claudia Schurman Stuart A Scott Ilkka Seppälä Christian Shaffer Svati Shah Alaa A Shalaby Jaemin Shim M Benjamin Shoemaker Joylene E Siland Juha Sinisalo Moritz F Sinner Agnieszka Slowik Albert V Smith Blair H Smith J Gustav Smith Jonathan D Smith Nicholas L Smith Elsayed Z Soliman Nona Sotoodehnia Bruno H Stricker Albert Sun Han Sun Jesper H Svendsen Toshihiro Tanaka Kahraman Tanriverdi Kent D Taylor Maris Teder-Laving Alexander Teumer Sébastien Thériault Stella Trompet Nathan R Tucker Arnljot Tveit Andre G Uitterlinden Pim Van Der Harst Isabelle C Van Gelder David R Van Wagoner Niek Verweij Efthymia Vlachopoulou Uwe Völker Biqi Wang Peter E Weeke Bob Weijs Raul Weiss Stefan Weiss Quinn S Wells Kerri L Wiggins Jorge A Wong Daniel Woo Bradford B Worrall Pil-Sung Yang Jie Yao Zachary T Yoneda Tanja Zeller Lingyao Zeng Steven A Lubitz Kathryn L Lunetta Patrick T Ellinor

Nat Genet 2018 06 11;50(9):1225-1233. Epub 2018 Jun 11.

Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41588-018-0133-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136836PMC
June 2018

Activation of the unfolded protein response downregulates cardiac ion channels in human induced pluripotent stem cell-derived cardiomyocytes.

J Mol Cell Cardiol 2018 04 21;117:62-71. Epub 2018 Feb 21.

Division of Cardiology, Dept. of Medicine, the Lillehei Heart Institute, University of Minnesota, Minneapolis, MN, United States. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2018.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861016PMC
April 2018

Mitochondrial Ca Influx Contributes to Arrhythmic Risk in Nonischemic Cardiomyopathy.

J Am Heart Assoc 2018 04 7;7(8). Epub 2018 Apr 7.

Department of Medicine, Lillehei Heart Institute, University of Minnesota, Minneapolis, MN

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http://dx.doi.org/10.1161/JAHA.117.007805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015427PMC
April 2018

RNA Binding Protein, HuR, Regulates Expression Through Stabilizing MEF2C transcription factor mRNA.

J Am Heart Assoc 2018 04 20;7(9). Epub 2018 Apr 20.

Department of Cardiology, Warren Alpert School of Medicine at Brown University, Providence, RI

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http://dx.doi.org/10.1161/JAHA.117.007802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015277PMC
April 2018

Abnormal sodium channel mRNA splicing in hypertrophic cardiomyopathy.

Int J Cardiol 2017 Dec 7;249:282-286. Epub 2017 Sep 7.

Department of Cardiology, Warren Alpert School of Medicine at Brown University, Providence, RI, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.08.071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681396PMC
December 2017

Role of protein kinase C in metabolic regulation of the cardiac Na channel.

Heart Rhythm 2017 03 15;14(3):440-447. Epub 2016 Dec 15.

Division of Cardiology, Department of Medicine, The Warren Alpert Medical School of Brown University, Lifespan Cardiovascular Institute, Providence, Rhode Island; Providence VA Medical Center, Providence, Rhode Island. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2016.12.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316355PMC
March 2017

SK channel enhancers attenuate Ca2+-dependent arrhythmia in hypertrophic hearts by regulating mito-ROS-dependent oxidation and activity of RyR.

Cardiovasc Res 2017 03;113(3):343-353

Department of Medicine, Division of Cardiology, Cardiovascular Research Center, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, 1 Hoppin Street, Providence, RI, 02903-4141, USA.

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http://dx.doi.org/10.1093/cvr/cvx005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852621PMC
March 2017

Serum amine-based metabolites and their association with outcomes in primary prevention implantable cardioverter-defibrillator patients.

Europace 2016 Sep 25;18(9):1383-90. Epub 2015 Oct 25.

Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Halsted 565, Baltimore, MD 21287, USA

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http://dx.doi.org/10.1093/europace/euv342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006959PMC
September 2016

Renin-Angiotensin Activation and Oxidative Stress in Early Heart Failure with Preserved Ejection Fraction.

Biomed Res Int 2015 4;2015:825027. Epub 2015 Oct 4.

Cardiovascular Research Center and Cardiovascular Institute of Lifespan, The Warren Alpert Medical School, Brown University, Providence, RI 02903, USA.

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http://dx.doi.org/10.1155/2015/825027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609374PMC
August 2016

Obstructive Sleep Apnea and Circulating Potassium Channel Levels.

J Am Heart Assoc 2016 08 19;5(8). Epub 2016 Aug 19.

Lifespan Cardiovascular Institute, Brown University, Providence, RI The Providence VA, Providence, RI

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http://dx.doi.org/10.1161/JAHA.116.003666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015289PMC
August 2016

Role of Mitochondrial Oxidative Stress in Glucose Tolerance, Insulin Resistance, and Cardiac Diastolic Dysfunction.

J Am Heart Assoc 2016 05 5;5(5). Epub 2016 May 5.

Cardiovascular Research Center, Lifespan Rhode Island Hospital, Providence, RI The Warren Alpert Medical School, Brown University, Providence, RI Providence Veterans Affairs Medical Center, Providence, RI

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http://dx.doi.org/10.1161/JAHA.115.003046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889180PMC
May 2016

Role for the Unfolded Protein Response in Heart Disease and Cardiac Arrhythmias.

Int J Mol Sci 2015 Dec 31;17(1). Epub 2015 Dec 31.

The Warren Alpert Medical School of Brown University, Lifespan Cardiovascular Institute, the Providence VA Medical Center, 593 Eddy Street, APC814, Providence, RI 02903, USA.

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http://dx.doi.org/10.3390/ijms17010052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730297PMC
December 2015

Diastolic dysfunction.

Circ J 2015 5;79(3):470-7. Epub 2015 Feb 5.

Cardiovascular Research Center and Cardiovascular Institute of Lifespan, The Warren Alpert Medical School, Brown University.

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http://dx.doi.org/10.1253/circj.CJ-15-0064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861951PMC
November 2015

Mechanisms of sudden cardiac death: oxidants and metabolism.

Circ Res 2015 Jun;116(12):1937-55

From the Department of Pharmacology (K.-C.Y.) and Division of Cardiology, Department of Internal Medicine (K.-C.Y.), National Taiwan University Hospital, Taipei, Taiwan; Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin, Madison (J.W.K., J.C.M.); and Lifespan Cardiovascular Institute, the Providence VA Medical Center, and Brown University, RI (S.C.D.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.304691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458707PMC
June 2015

Nitroglycerin tolerance in caveolin-1 deficient mice.

PLoS One 2014 26;9(8):e104101. Epub 2014 Aug 26.

Department of Medicine-Section of Cardiology, University of Illinois at Chicago, Chicago, Illinois, United States of America; Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104101PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144835PMC
May 2015

A Circulating Biomarker Risk-Prediction Model Correlates with CHADS-2 Risk Score in Chronic Atrial Fibrillation.

IJC Metab Endocr 2015 Mar;6:24-26

Lifespan Cardiovascular Institute and the Warren Alpert Medical School of Brown University, Providence, RI.

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http://dx.doi.org/10.1016/j.ijcme.2015.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335707PMC
March 2015

Cardiac sodium channel mutations: why so many phenotypes?

Nat Rev Cardiol 2014 Oct 24;11(10):607-15. Epub 2014 Jun 24.

Warren Alpert Medical School, Brown University, 593 Eddy Street, APC730, Providence, RI 02903, USA.

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http://dx.doi.org/10.1038/nrcardio.2014.85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878851PMC
October 2014

Caveolin-1 modulates cardiac gap junction homeostasis and arrhythmogenecity by regulating cSrc tyrosine kinase.

Circ Arrhythm Electrophysiol 2014 Aug 13;7(4):701-10. Epub 2014 Jul 13.

From the Lifespan Cardiovascular Research Center, Department of Medicine, Warren Alpert School of Medicine, Brown University, Providence Veterans Administration Medical Center, RI (K.-C.Y., C.A.R., A.X., H.L., S.C.D.); Department of Medicine (K.-C.Y., C.A.R.), Department of Pharmacology (M.M., M.G.B., R.D.M.), and Department of Anesthesiology (F.R.B., R.D.M.), University of Illinois at Chicago; and Department of Anesthesiology, VA San Diego Healthcare Systems, University of California (H.H.P.).

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http://dx.doi.org/10.1161/CIRCEP.113.001394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198950PMC
August 2014

Targeting the unfolded protein response in heart diseases.

Expert Opin Ther Targets 2014 Jul 28;18(7):719-23. Epub 2014 May 28.

Brown University, Lifespan Cardiovascular Institute, The Providence VA Medical Center , Providence, RI , USA.

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http://dx.doi.org/10.1517/14728222.2014.918605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878849PMC
July 2014

Mitochondria and arrhythmias.

Free Radic Biol Med 2014 Jun 5;71:351-61. Epub 2014 Apr 5.

Lifespan Cardiovascular Institute, Providence VA Medical Center, and Brown University, Providence, RI 02903, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2014.03.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096785PMC
June 2014

c-Src kinase inhibition reduces arrhythmia inducibility and connexin43 dysregulation after myocardial infarction.

J Am Coll Cardiol 2014 Mar 8;63(9):928-34. Epub 2014 Jan 8.

Lifespan Cardiovascular Institute, the Warren Alpert School of Medicine of Brown University, and the Providence Veterans Administration Medical Center, Providence. Rhode Island. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2013.10.081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963804PMC
March 2014

New diagnostic and therapeutic possibilities for diastolic heart failure.

R I Med J (2013) 2014 Feb 3;97(2):35-7. Epub 2014 Feb 3.

Chief of Cardiology, The Miriam and Rhode Island Hospitals and Brown University; Director, Lifespan Cardiovascular Institute; and the Ruth and Paul Levinger Professor of Cardiology, The Warren Alpert Medical School of Brown University.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211876PMC
February 2014

Oxidative stress and atrial fibrillation: finding a missing piece to the puzzle.

Circulation 2013 Oct 12;128(16):1724-6. Epub 2013 Sep 12.

Lifespan Cardiovascular Institute, the Warren Alpert School of Medicine, Brown University, and the Providence Veterans Administration Medical Center, Providence, RI.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.005837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909513PMC
October 2013

Unfolded protein response regulates cardiac sodium current in systolic human heart failure.

Circ Arrhythm Electrophysiol 2013 Oct 13;6(5):1018-24. Epub 2013 Sep 13.

Lifespan Cardiovascular Research Center, the Warren Alpert School of Medicine, Brown University and Providence Veterans Administration Medical Center, Providence, RI.

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http://dx.doi.org/10.1161/CIRCEP.113.000274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909518PMC
October 2013

Mitochondria oxidative stress, connexin43 remodeling, and sudden arrhythmic death.

Circ Arrhythm Electrophysiol 2013 Jun 4;6(3):623-31. Epub 2013 Apr 4.

Section of Cardiology and Center for Cardiovascular Research, University of Illinois at Chicago, IL, USA.

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http://dx.doi.org/10.1161/CIRCEP.112.976787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716298PMC
June 2013

Modulation of human mesenchymal stem cell function in a three-dimensional matrix promotes attenuation of adverse remodelling after myocardial infarction.

J Tissue Eng Regen Med 2013 Mar 18;7(3):192-202. Epub 2011 Nov 18.

University of Illinois at Chicago, IL 60612, USA.

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http://dx.doi.org/10.1002/term.511DOI Listing
March 2013

Tetrahydrobiopterin improves diastolic dysfunction by reversing changes in myofilament properties.

J Mol Cell Cardiol 2013 Mar 14;56:44-54. Epub 2012 Dec 14.

Department of Medicine, Section of Cardiology, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2012.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666585PMC
March 2013

RBM25/LUC7L3 function in cardiac sodium channel splicing regulation of human heart failure.

Trends Cardiovasc Med 2013 Jan 31;23(1):5-8. Epub 2012 Aug 31.

Section of Cardiology, Department of Medicine, University of Illinois at Chicago and the Jesse Brown VA Medical Center, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1016/j.tcm.2012.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532530PMC
January 2013

Mitochondrial dysfunction causing cardiac sodium channel downregulation in cardiomyopathy.

J Mol Cell Cardiol 2013 Jan 1;54:25-34. Epub 2012 Nov 1.

Section of Cardiology, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2012.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595554PMC
January 2013

Determination of ebselen-sensitive reactive oxygen metabolites (ebROM) in human serum based upon N,N'-diethyl-1,4-phenylenediamine oxidation.

Clin Chim Acta 2012 Dec 8;414:1-6. Epub 2012 Jun 8.

Clinical Biomarkers Laboratory, Allergy and Critical Care Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, United States.

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http://dx.doi.org/10.1016/j.cca.2012.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662006PMC
December 2012

Association of low plasma adiponectin with early diastolic dysfunction.

Congest Heart Fail 2012 Jul-Aug;18(4):187-91. Epub 2012 Jan 9.

Section of Cardiology, University of Illinois at Chicago, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1111/j.1751-7133.2011.00276.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646250PMC
December 2012

Reactive oxygen species-targeted therapeutic interventions for atrial fibrillation.

Front Physiol 2012 6;3:311. Epub 2012 Aug 6.

Section of Cardiology, Center for Cardiovascular Research, University of Illinois at Chicago Chicago, IL, USA.

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http://dx.doi.org/10.3389/fphys.2012.00311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429082PMC
October 2012

Metabolic stress, reactive oxygen species, and arrhythmia.

J Mol Cell Cardiol 2012 Feb 25;52(2):454-63. Epub 2011 Sep 25.

Section of Cardiology, University of Illinois at Chicago, Chicago, IL 60612, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00222828110042
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http://dx.doi.org/10.1016/j.yjmcc.2011.09.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264827PMC
February 2012

Use of human embryonic stem cell derived-mesenchymal cells for cardiac repair.

Biotechnol Bioeng 2012 Jan 2;109(1):274-83. Epub 2011 Sep 2.

University of Illinois at Chicago/Jesse Brown VA Medical Center, 840 S. Wood Street, MC715, Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1002/bit.23301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220775PMC
January 2012

Inhibition of c-Src tyrosine kinase prevents angiotensin II-mediated connexin-43 remodeling and sudden cardiac death.

J Am Coll Cardiol 2011 Nov;58(22):2332-9

Section of Cardiology and Center for Cardiovascular Research, University of Illinois at Chicago, 840 S.Wood Street, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1016/j.jacc.2011.07.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226807PMC
November 2011

Diastolic dysfunction is associated with cardiac fibrosis in the senescence-accelerated mouse.

Am J Physiol Heart Circ Physiol 2011 Sep 1;301(3):H824-31. Epub 2011 Jul 1.

Division of Pulmonary, Allergy and Critical Care Medicine, Emory University School of Medicine/Atlanta Veterans Affairs Medical Center, Atlanta, Georgia 30033, USA.

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http://dx.doi.org/10.1152/ajpheart.00407.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191096PMC
September 2011

Statins Decrease Oxidative Stress and ICD Therapies.

Cardiol Res Pract 2010 25;2010:253803. Epub 2010 Mar 25.

Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.

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https://www.hindawi.com/journals/crp/2010/253803/
Publisher Site
http://dx.doi.org/10.4061/2010/253803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847377PMC
July 2011

Statin therapy for the prevention of atrial fibrillation trial (SToP AF trial).

J Cardiovasc Electrophysiol 2011 Apr 13;22(4):414-9. Epub 2010 Oct 13.

Section of Cardiology, University of Illinois at Chicago, Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1111/j.1540-8167.2010.01925.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022954PMC
April 2011

Ion channelopathies: a tapped-out mine?

Authors:
Samuel C Dudley

Am J Physiol Heart Circ Physiol 2011 Mar 30;300(3):H716-7. Epub 2010 Dec 30.

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http://www.physiology.org/doi/10.1152/ajpheart.01281.2010
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http://dx.doi.org/10.1152/ajpheart.01281.2010DOI Listing
March 2011

Atrial fibrillation: the emerging role of inflammation and oxidative stress.

Cardiovasc Hematol Disord Drug Targets 2010 Dec;10(4):262-8

University of Illinois at Chicago, 60612, USA.

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http://dx.doi.org/10.2174/187152910793743850DOI Listing
December 2010

The tail of the cardiac sodium channel.

Channels (Austin) 2008 May-Jun;2(3):161-2. Epub 2008 May 24.

Section of Cardiology, University of Illinois at Chicago, Chicago, Illinois 60612, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153466PMC
http://dx.doi.org/10.4161/chan.2.3.6189DOI Listing
October 2010

Reactive oxygen species originating from mitochondria regulate the cardiac sodium channel.

Circ Res 2010 Oct 19;107(8):967-74. Epub 2010 Aug 19.

Jr, Section of Cardiology, University of Illinois at Chicago/Jesse Brown VA Medical Center, 840 S Wood St, MC715, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.110.220673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955818PMC
October 2010

Using serum transforming growth factor-beta to predict myocardial fibrosis.

Circ Res 2010 Mar;106(4):e3; author reply e4

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http://dx.doi.org/10.1161/CIRCRESAHA.109.215921DOI Listing
March 2010

Cardiac Na+ current regulation by pyridine nucleotides.

Circ Res 2009 Oct 10;105(8):737-45. Epub 2009 Sep 10.

Division in Cardiology, University of Illinois at Chicago and the Jesse Brown Veteran Affairs Medical Center, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.109.197277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773656PMC
October 2009

Redox regulation, NF-kappaB, and atrial fibrillation.

Antioxid Redox Signal 2009 Sep;11(9):2265-77

Section of Cardiology, University of Illinois at Chicago, and the Jesse Brown VA Medical Center, Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1089/ars.2009.2595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819799PMC
September 2009

Lost in translation: what is limiting cardiomyoplasty and can tissue engineering help?

Curr Stem Cell Res Ther 2009 Sep;4(3):210-23

Georgia Institute of Technology, Atlanta, GA 30332, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164232PMC
http://dx.doi.org/10.2174/157488809789057437DOI Listing
September 2009

Docking of mu-conotoxin GIIIA in the sodium channel outer vestibule.

Channels (Austin) 2007 Sep-Oct;1(5):344-52. Epub 2007 Oct 3.

Department of Medicine, Providence Veterans Affairs Medical Center/Brown University, Providence, Rhode Island 02904, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212855PMC
http://dx.doi.org/10.4161/chan.5112DOI Listing
November 2008

Sudden death in myotonic dystrophy.

N Engl J Med 2008 Oct;359(15):1628; author reply 1328-9

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October 2008

The renin-angiotensin-aldosterone system (RAAS) and cardiac arrhythmias.

Heart Rhythm 2008 Jun 4;5(6 Suppl):S12-7. Epub 2008 Mar 4.

Division of Cardiology, Department of Medicine, Emory University, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1016/j.hrthm.2008.02.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600881PMC
June 2008

Time to defibrillation after in-hospital cardiac arrest.

N Engl J Med 2008 Apr;358(15):1632-3; author reply 1633-4

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April 2008

NF-kappaB-dependent transcriptional regulation of the cardiac scn5a sodium channel by angiotensin II.

Am J Physiol Cell Physiol 2008 Jan 21;294(1):C372-9. Epub 2007 Nov 21.

Division of Cardiology, Department of Medicine, Emory University, Atlanta, Georgia, USA.

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http://www.physiology.org/doi/10.1152/ajpcell.00186.2007
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http://dx.doi.org/10.1152/ajpcell.00186.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150844PMC
January 2008

Speeding the recovery from ultraslow inactivation of voltage-gated Na+ channels by metal ion binding to the selectivity filter: a foot-on-the-door?

Biophys J 2007 Dec 24;93(12):4209-24. Epub 2007 Aug 24.

Center for Biomolecular Medicine and Pharmacology, Institute of Pharmacology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1529/biophysj.107.104794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2098733PMC
December 2007

A tissue engineering approach to progenitor cell delivery results in significant cell engraftment and improved myocardial remodeling.

Stem Cells 2007 Sep 24;25(9):2350-7. Epub 2007 May 24.

Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1634/stemcells.2007-0132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158658PMC
September 2007

Oxidative stress markers are associated with persistent atrial fibrillation.

Clin Chem 2007 Sep 28;53(9):1652-7. Epub 2007 Jun 28.

Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1373/clinchem.2006.083923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158654PMC
September 2007

A sodium channel pore mutation causing Brugada syndrome.

Heart Rhythm 2007 Jan 28;4(1):46-53. Epub 2006 Sep 28.

Division of Cardiology, Atlanta Veterans Affairs Medical Center and Emory University, Atlanta, Georgia 30033, USA.

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http://dx.doi.org/10.1016/j.hrthm.2006.09.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779366PMC
January 2007

A possible mechanism of halocarbon-induced cardiac sensitization arrhythmias.

J Mol Cell Cardiol 2006 Oct 17;41(4):698-705. Epub 2006 Aug 17.

Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, and Atlanta Veterans Affairs Medical Center, Decatur, GA 30033, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2006.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169205PMC
October 2006

Early determinants of H2O2-induced endothelial dysfunction.

Free Radic Biol Med 2006 Sep 3;41(5):810-7. Epub 2006 Jun 3.

Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30322, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S089158490600360
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http://dx.doi.org/10.1016/j.freeradbiomed.2006.05.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592456PMC
September 2006

Analysis of arrhythmic potential of embryonic stem cell-derived cardiomyocytes.

Methods Mol Biol 2006 ;330:221-31

Division of Cardiology Atlanta, Emory University, Decatur, GA, USA.

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http://dx.doi.org/10.1385/1-59745-036-7:221DOI Listing
August 2006

Rapid pacing of embryoid bodies impairs mitochondrial ATP synthesis by a calcium-dependent mechanism--a model of in vitro differentiated cardiomyocytes to study molecular effects of tachycardia.

Biochim Biophys Acta 2006 Jun 19;1762(6):608-15. Epub 2006 Apr 19.

Institute of Clinical Chemistry, Department of Pathobiochemistry, Otto-von-Guericke University Magdeburg, and Division of Cardiology, University Hospital Magdeburg, Germany.

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http://dx.doi.org/10.1016/j.bbadis.2006.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153943PMC
June 2006

The measurement of nitric oxide production by cultured endothelial cells.

Methods Enzymol 2005 ;396:502-14

Department of Medicine, Emory University, Atlanta VA Medical Center, Decatur, Georgia 30033, USA.

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http://dx.doi.org/10.1016/S0076-6879(05)96042-4DOI Listing
January 2006

Tandem promoters and developmentally regulated 5'- and 3'-mRNA untranslated regions of the mouse Scn5a cardiac sodium channel.

J Biol Chem 2005 Jan 14;280(2):933-40. Epub 2004 Oct 14.

Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1074/jbc.M409977200DOI Listing
January 2005

Lidocaine: a foot in the door of the inner vestibule prevents ultra-slow inactivation of a voltage-gated sodium channel.

Mol Pharmacol 2004 Sep;66(3):648-57

Medical University of Vienna, Institute of Pharmacology, Währingerstrasse 13A, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1124/mol.66.3.DOI Listing
September 2004

A program encouraging early defibrillation results in improved in-hospital resuscitation efficacy.

J Am Coll Cardiol 2004 Aug;44(4):846-52

Emory University School of Medicine, Department of Medicine, Division of Cardiology, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1016/j.jacc.2004.04.054DOI Listing
August 2004

Fatty acids differentially modulate insulin-stimulated endothelial nitric oxide production by an Akt-independent pathway.

J Investig Med 2004 Mar;52(2):129-36

Department ofMedicine, Veterans Affairs Medical Center, 151 -P 1670 Clairmont Rd, Decatur, GA 30033 , USA.

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http://dx.doi.org/10.1136/jim-52-02-22DOI Listing
March 2004

The structure of zetekitoxin AB, a saxitoxin analog from the Panamanian golden frog Atelopus zeteki: a potent sodium-channel blocker.

Proc Natl Acad Sci U S A 2004 Mar 22;101(13):4346-51. Epub 2004 Mar 22.

Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan.

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http://dx.doi.org/10.1073/pnas.0400368101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC384749PMC
March 2004