Samuel C Dudley

Samuel C Dudley

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Samuel C Dudley

Publications by authors named "Samuel C Dudley"

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Isolevuglandin scavenger attenuates pressure overload-induced cardiac oxidative stress, cardiac hypertrophy, heart failure and lung remodeling.

Authors:
Linlin Shang Xinyu Weng Dongzhi Wang Wenhui Yue Ray Mernaugh Venkataraman Amarnath E Kenneth Weir Samuel C Dudley Yawei Xu Mingxiao Hou Yingjie Chen

Free Radic Biol Med 2019 Sep 26;141:291-298. Epub 2019 Jun 26.

Lillehei Heart Institute and Cardiovascular Division, University of Minnesota Medical School, Minneapolis, MN, 55455, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2019.06.029DOI Listing
September 2019

The role of the unfolded protein response in arrhythmias.

Authors:
Man Liu Samuel C Dudley

Channels (Austin) 2018 ;12(1):335-345

a Division of Cardiology, Department of Medicine, The Lillehei Heart Institute , University of Minnesota at Twin Cities , Minneapolis , USA.

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http://dx.doi.org/10.1080/19336950.2018.1516985DOI Listing
August 2019

Short term Pm2.5 exposure caused a robust lung inflammation, vascular remodeling, and exacerbated transition from left ventricular failure to right ventricular hypertrophy.

Authors:
Wenhui Yue Lei Tong Xiaohong Liu Xinyu Weng Xiaoyu Chen Dongzhi Wang Samuel C Dudley E Kenneth Weir Wenjun Ding Zhongbing Lu Yawei Xu Yingjie Chen

Redox Biol 2019 04 6;22:101161. Epub 2019 Mar 6.

Cardiovascular Division and Lillehei Heart Institute, University of Minnesota Medical School, Minneapolis, MN 55455, USA. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2019.101161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411784PMC
April 2019

Mitochondrial Ca2+ flux modulates spontaneous electrical activity in ventricular cardiomyocytes.

Authors:
An Xie Anyu Zhou Hong Liu Guangbin Shi Man Liu Kenneth R Boheler Samuel C Dudley

PLoS One 2018 12;13(7):e0200448. Epub 2018 Jul 12.

Department of Medicine, Lillehei Heart Institute, University of Minnesota, Minneapolis, MN, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0200448PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042741PMC
January 2019

Magnesium supplementation improves diabetic mitochondrial and cardiac diastolic function.

Authors:
Man Liu Euy-Myoung Jeong Hong Liu An Xie Eui Young So Guangbin Shi Go Eun Jeong Anyu Zhou Samuel C Dudley

JCI Insight 2019 Jan 10;4(1). Epub 2019 Jan 10.

Division of Cardiology, Department of Medicine, the Lillehei Heart Institute, University of Minnesota at Twin Cities, Minneapolis, Minnesota.

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https://insight.jci.org/articles/view/123182
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http://dx.doi.org/10.1172/jci.insight.123182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485371PMC
January 2019

Functional cardiac Na channels are expressed in human melanoma cells.

Authors:
An Xie Benjamin Gallant Hao Guo Alfredo Gonzalez Matthew Clark Audrey Madigan Feng Feng Hong-Duo Chen Yali Cui Samuel C Dudley Yinsheng Wan

Oncol Lett 2018 Aug 31;16(2):1689-1695. Epub 2018 May 31.

Department of Biology, Providence College, Providence, RI 02918, USA.

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http://dx.doi.org/10.3892/ol.2018.8865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036419PMC
August 2018

HuR-mediated SCN5A messenger RNA stability reduces arrhythmic risk in heart failure.

Authors:
Anyu Zhou An Xie Tae Yun Kim Hong Liu Guangbin Shi Gyeoung-Jin Kang Ning Jiang Man Liu Euy-Myoung Jeong Bum-Rak Choi Samuel C Dudley

Heart Rhythm 2018 07 16;15(7):1072-1080. Epub 2018 Feb 16.

Department of Cardiology, The Warren Alpert Medical School of Brown University, Providence, Rhode Island; The Lillehei Heart Institute, University of Minnesota, Minneapolis, Minnesota. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2018.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026071PMC
July 2018

Multi-ethnic genome-wide association study for atrial fibrillation.

Authors:
Carolina Roselli Mark D Chaffin Lu-Chen Weng Stefanie Aeschbacher Gustav Ahlberg Christine M Albert Peter Almgren Alvaro Alonso Christopher D Anderson Krishna G Aragam Dan E Arking John Barnard Traci M Bartz Emelia J Benjamin Nathan A Bihlmeyer Joshua C Bis Heather L Bloom Eric Boerwinkle Erwin B Bottinger Jennifer A Brody Hugh Calkins Archie Campbell Thomas P Cappola John Carlquist Daniel I Chasman Lin Y Chen Yii-Der Ida Chen Eue-Keun Choi Seung Hoan Choi Ingrid E Christophersen Mina K Chung John W Cole David Conen James Cook Harry J Crijns Michael J Cutler Scott M Damrauer Brian R Daniels Dawood Darbar Graciela Delgado Joshua C Denny Martin Dichgans Marcus Dörr Elton A Dudink Samuel C Dudley Nada Esa Tonu Esko Markku Eskola Diane Fatkin Stephan B Felix Ian Ford Oscar H Franco Bastiaan Geelhoed Raji P Grewal Vilmundur Gudnason Xiuqing Guo Namrata Gupta Stefan Gustafsson Rebecca Gutmann Anders Hamsten Tamara B Harris Caroline Hayward Susan R Heckbert Jussi Hernesniemi Lynne J Hocking Albert Hofman Andrea R V R Horimoto Jie Huang Paul L Huang Jennifer Huffman Erik Ingelsson Esra Gucuk Ipek Kaoru Ito Jordi Jimenez-Conde Renee Johnson J Wouter Jukema Stefan Kääb Mika Kähönen Yoichiro Kamatani John P Kane Adnan Kastrati Sekar Kathiresan Petra Katschnig-Winter Maryam Kavousi Thorsten Kessler Bas L Kietselaer Paulus Kirchhof Marcus E Kleber Stacey Knight Jose E Krieger Michiaki Kubo Lenore J Launer Jari Laurikka Terho Lehtimäki Kirsten Leineweber Rozenn N Lemaitre Man Li Hong Euy Lim Henry J Lin Honghuang Lin Lars Lind Cecilia M Lindgren Marja-Liisa Lokki Barry London Ruth J F Loos Siew-Kee Low Yingchang Lu Leo-Pekka Lyytikäinen Peter W Macfarlane Patrik K Magnusson Anubha Mahajan Rainer Malik Alfredo J Mansur Gregory M Marcus Lauren Margolin Kenneth B Margulies Winfried März David D McManus Olle Melander Sanghamitra Mohanty Jay A Montgomery Michael P Morley Andrew P Morris Martina Müller-Nurasyid Andrea Natale Saman Nazarian Benjamin Neumann Christopher Newton-Cheh Maartje N Niemeijer Kjell Nikus Peter Nilsson Raymond Noordam Heidi Oellers Morten S Olesen Marju Orho-Melander Sandosh Padmanabhan Hui-Nam Pak Guillaume Paré Nancy L Pedersen Joanna Pera Alexandre Pereira David Porteous Bruce M Psaty Sara L Pulit Clive R Pullinger Daniel J Rader Lena Refsgaard Marta Ribasés Paul M Ridker Michiel Rienstra Lorenz Risch Dan M Roden Jonathan Rosand Michael A Rosenberg Natalia Rost Jerome I Rotter Samir Saba Roopinder K Sandhu Renate B Schnabel Katharina Schramm Heribert Schunkert Claudia Schurman Stuart A Scott Ilkka Seppälä Christian Shaffer Svati Shah Alaa A Shalaby Jaemin Shim M Benjamin Shoemaker Joylene E Siland Juha Sinisalo Moritz F Sinner Agnieszka Slowik Albert V Smith Blair H Smith J Gustav Smith Jonathan D Smith Nicholas L Smith Elsayed Z Soliman Nona Sotoodehnia Bruno H Stricker Albert Sun Han Sun Jesper H Svendsen Toshihiro Tanaka Kahraman Tanriverdi Kent D Taylor Maris Teder-Laving Alexander Teumer Sébastien Thériault Stella Trompet Nathan R Tucker Arnljot Tveit Andre G Uitterlinden Pim Van Der Harst Isabelle C Van Gelder David R Van Wagoner Niek Verweij Efthymia Vlachopoulou Uwe Völker Biqi Wang Peter E Weeke Bob Weijs Raul Weiss Stefan Weiss Quinn S Wells Kerri L Wiggins Jorge A Wong Daniel Woo Bradford B Worrall Pil-Sung Yang Jie Yao Zachary T Yoneda Tanja Zeller Lingyao Zeng Steven A Lubitz Kathryn L Lunetta Patrick T Ellinor

Nat Genet 2018 06 11;50(9):1225-1233. Epub 2018 Jun 11.

Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41588-018-0133-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136836PMC
June 2018

Activation of the unfolded protein response downregulates cardiac ion channels in human induced pluripotent stem cell-derived cardiomyocytes.

Authors:
Man Liu Guangbin Shi Anyu Zhou Cassady E Rupert Kareen L K Coulombe Samuel C Dudley

J Mol Cell Cardiol 2018 04 21;117:62-71. Epub 2018 Feb 21.

Division of Cardiology, Dept. of Medicine, the Lillehei Heart Institute, University of Minnesota, Minneapolis, MN, United States. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2018.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861016PMC
April 2018

Mitochondrial Ca Influx Contributes to Arrhythmic Risk in Nonischemic Cardiomyopathy.

Authors:
An Xie Zhen Song Hong Liu Anyu Zhou Guangbin Shi Qiongying Wang Lianzhi Gu Man Liu Lai-Hua Xie Zhilin Qu Samuel C Dudley

J Am Heart Assoc 2018 04 7;7(8). Epub 2018 Apr 7.

Department of Medicine, Lillehei Heart Institute, University of Minnesota, Minneapolis, MN

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http://dx.doi.org/10.1161/JAHA.117.007805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015427PMC
April 2018

RNA Binding Protein, HuR, Regulates Expression Through Stabilizing MEF2C transcription factor mRNA.

Authors:
Anyu Zhou Guangbin Shi Gyeoung-Jin Kang An Xie Hong Liu Ning Jiang Man Liu Euy-Myoung Jeong Samuel C Dudley

J Am Heart Assoc 2018 04 20;7(9). Epub 2018 Apr 20.

Department of Cardiology, Warren Alpert School of Medicine at Brown University, Providence, RI

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http://dx.doi.org/10.1161/JAHA.117.007802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015277PMC
April 2018

A common variant alters SCN5A-miR-24 interaction and associates with heart failure mortality.

Authors:
Xiaoming Zhang Jin-Young Yoon Michael Morley Jared M McLendon Kranti A Mapuskar Rebecca Gutmann Haider Mehdi Heather L Bloom Samuel C Dudley Patrick T Ellinor Alaa A Shalaby Raul Weiss W H Wilson Tang Christine S Moravec Madhurmeet Singh Anne L Taylor Clyde W Yancy Arthur M Feldman Dennis M McNamara Kaikobad Irani Douglas R Spitz Patrick Breheny Kenneth B Margulies Barry London Ryan L Boudreau

J Clin Invest 2018 03 19;128(3):1154-1163. Epub 2018 Feb 19.

Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.

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http://dx.doi.org/10.1172/JCI95710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824852PMC
March 2018

Abnormal sodium channel mRNA splicing in hypertrophic cardiomyopathy.

Authors:
Adam M Noyes Anyu Zhou Ge Gao Lianzhi Gu Sharlene Day J Andrew Wasserstrom Samuel C Dudley

Int J Cardiol 2017 Dec 7;249:282-286. Epub 2017 Sep 7.

Department of Cardiology, Warren Alpert School of Medicine at Brown University, Providence, RI, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.08.071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681396PMC
December 2017

Associations of Prolonged QTc in Sickle Cell Disease.

Authors:
Julia H Indik Vineet Nair Ruslan Rafikov Iwan S Nyotowidjojo Jaskanwal Bisla Mayank Kansal Devang S Parikh Melissa Robinson Anand Desai Megha Oberoi Akash Gupta Taimur Abbasi Zain Khalpey Amit R Patel Roberto M Lang Samuel C Dudley Bum-Rak Choi Joe G N Garcia Roberto F Machado Ankit A Desai

PLoS One 2016 13;11(10):e0164526. Epub 2016 Oct 13.

Department of Medicine and Arizona Health Sciences Center, University of Arizona, Tucson, AZ, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0164526PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063274PMC
May 2017

Effect of α7 nicotinic acetylcholine receptor activation on cardiac fibroblasts: a mechanism underlying RV fibrosis associated with cigarette smoke exposure.

Authors:
Alexander Vang Richard T Clements Havovi Chichger Nouaying Kue Ayed Allawzi Kelly O'Connell Euy-Myoung Jeong Samuel C Dudley Pavlo Sakhatskyy Qing Lu Peng Zhang Sharon Rounds Gaurav Choudhary

Am J Physiol Lung Cell Mol Physiol 2017 05 3;312(5):L748-L759. Epub 2017 Mar 3.

Vascular Research Laboratory, Providence Veterans Affairs Medical Center, Providence, Rhode Island;

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http://dx.doi.org/10.1152/ajplung.00393.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451597PMC
May 2017

Role of protein kinase C in metabolic regulation of the cardiac Na channel.

Authors:
Man Liu Guangbin Shi Kai-Chien Yang Lianzhi Gu Anumantha G Kanthasamy Vellareddy Anantharam Samuel C Dudley

Heart Rhythm 2017 03 15;14(3):440-447. Epub 2016 Dec 15.

Division of Cardiology, Department of Medicine, The Warren Alpert Medical School of Brown University, Lifespan Cardiovascular Institute, Providence, Rhode Island; Providence VA Medical Center, Providence, Rhode Island. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2016.12.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316355PMC
March 2017

SK channel enhancers attenuate Ca2+-dependent arrhythmia in hypertrophic hearts by regulating mito-ROS-dependent oxidation and activity of RyR.

Authors:
Tae Yun Kim Radmila Terentyeva Karim H F Roder Weiyan Li Man Liu Ian Greener Shanna Hamilton Iuliia Polina Kevin R Murphy Richard T Clements Samuel C Dudley Gideon Koren Bum-Rak Choi Dmitry Terentyev

Cardiovasc Res 2017 03;113(3):343-353

Department of Medicine, Division of Cardiology, Cardiovascular Research Center, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, 1 Hoppin Street, Providence, RI, 02903-4141, USA.

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http://dx.doi.org/10.1093/cvr/cvx005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852621PMC
March 2017

Serum amine-based metabolites and their association with outcomes in primary prevention implantable cardioverter-defibrillator patients.

Authors:
Yiyi Zhang Elena Blasco-Colmenares Amy C Harms Barry London Indrani Halder Madhurmeet Singh Samuel C Dudley Rebecca Gutmann Eliseo Guallar Thomas Hankemeier Gordon F Tomaselli Alan Cheng

Europace 2016 Sep 25;18(9):1383-90. Epub 2015 Oct 25.

Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Halsted 565, Baltimore, MD 21287, USA

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http://dx.doi.org/10.1093/europace/euv342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006959PMC
September 2016

Renin-Angiotensin Activation and Oxidative Stress in Early Heart Failure with Preserved Ejection Fraction.

Authors:
Smita I Negi Euy-Myoung Jeong Irfan Shukrullah Emir Veleder Dean P Jones Tai-Hwang M Fan Sudhahar Varadarajan Sergei M Danilov Tohru Fukai Samuel C Dudley

Biomed Res Int 2015 4;2015:825027. Epub 2015 Oct 4.

Cardiovascular Research Center and Cardiovascular Institute of Lifespan, The Warren Alpert Medical School, Brown University, Providence, RI 02903, USA.

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http://dx.doi.org/10.1155/2015/825027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609374PMC
August 2016

Obstructive Sleep Apnea and Circulating Potassium Channel Levels.

Authors:
Ning Jiang Anyu Zhou Bharati Prasad Li Zhou Jimmy Doumit Guangbin Shi Hafiz Imran Bahaa Kaseer Richard Millman Samuel C Dudley

J Am Heart Assoc 2016 08 19;5(8). Epub 2016 Aug 19.

Lifespan Cardiovascular Institute, Brown University, Providence, RI The Providence VA, Providence, RI

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http://dx.doi.org/10.1161/JAHA.116.003666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015289PMC
August 2016

Role of Mitochondrial Oxidative Stress in Glucose Tolerance, Insulin Resistance, and Cardiac Diastolic Dysfunction.

Authors:
Euy-Myoung Jeong Jaehoon Chung Hong Liu Yeongju Go Scott Gladstein Afshin Farzaneh-Far E Douglas Lewandowski Samuel C Dudley

J Am Heart Assoc 2016 05 5;5(5). Epub 2016 May 5.

Cardiovascular Research Center, Lifespan Rhode Island Hospital, Providence, RI The Warren Alpert Medical School, Brown University, Providence, RI Providence Veterans Affairs Medical Center, Providence, RI

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http://dx.doi.org/10.1161/JAHA.115.003046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889180PMC
May 2016

Role for the Unfolded Protein Response in Heart Disease and Cardiac Arrhythmias.

Authors:
Man Liu Samuel C Dudley

Int J Mol Sci 2015 Dec 31;17(1). Epub 2015 Dec 31.

The Warren Alpert Medical School of Brown University, Lifespan Cardiovascular Institute, the Providence VA Medical Center, 593 Eddy Street, APC814, Providence, RI 02903, USA.

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http://dx.doi.org/10.3390/ijms17010052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730297PMC
December 2015

Diastolic dysfunction.

Authors:
Euy-Myoung Jeong Samuel C Dudley

Circ J 2015 5;79(3):470-7. Epub 2015 Feb 5.

Cardiovascular Research Center and Cardiovascular Institute of Lifespan, The Warren Alpert Medical School, Brown University.

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http://dx.doi.org/10.1253/circj.CJ-15-0064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861951PMC
November 2015

Left Ventricular Dilatation Increases the Risk of Ventricular Arrhythmias in Patients With Reduced Systolic Function.

Authors:
Ryan G Aleong Matthew J Mulvahill Indrani Halder Nichole E Carlson Madhurmeet Singh Heather L Bloom Samuel C Dudley Patrick T Ellinor Alaa Shalaby Raul Weiss Rebecca Gutmann William H Sauer Kumar Narayanan Sumeet S Chugh Samir Saba Barry London

J Am Heart Assoc 2015 Jul 31;4(8):e001566. Epub 2015 Jul 31.

University of Iowa, Iowa City, IA (R.G., B.L.).

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http://dx.doi.org/10.1161/JAHA.114.001566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599449PMC
July 2015

Mechanisms of sudden cardiac death: oxidants and metabolism.

Authors:
Kai-Chien Yang John W Kyle Jonathan C Makielski Samuel C Dudley

Circ Res 2015 Jun;116(12):1937-55

From the Department of Pharmacology (K.-C.Y.) and Division of Cardiology, Department of Internal Medicine (K.-C.Y.), National Taiwan University Hospital, Taipei, Taiwan; Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin, Madison (J.W.K., J.C.M.); and Lifespan Cardiovascular Institute, the Providence VA Medical Center, and Brown University, RI (S.C.D.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.304691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458707PMC
June 2015

Nitroglycerin tolerance in caveolin-1 deficient mice.

Authors:
Mao Mao Sudhahar Varadarajan Tohru Fukai Farnaz R Bakhshi Olga Chernaya Samuel C Dudley Richard D Minshall Marcelo G Bonini

PLoS One 2014 26;9(8):e104101. Epub 2014 Aug 26.

Department of Medicine-Section of Cardiology, University of Illinois at Chicago, Chicago, Illinois, United States of America; Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104101PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144835PMC
May 2015

Effect of angiotensin-converting enzyme inhibitors and receptor blockers on appropriate implantable cardiac defibrillator shock in patients with severe systolic heart failure (from the GRADE Multicenter Study).

Authors:
Wael A AlJaroudi Marwan M Refaat Robert H Habib Laila Al-Shaar Madhurmeet Singh Rebecca Gutmann Heather L Bloom Samuel C Dudley Patrick T Ellinor Samir F Saba Alaa A Shalaby Raul Weiss Dennis M McNamara Indrani Halder Barry London

Am J Cardiol 2015 Apr 15;115(7):924-31. Epub 2015 Jan 15.

Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA.

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https://linkinghub.elsevier.com/retrieve/pii/S00029149150005
Publisher Site
http://dx.doi.org/10.1016/j.amjcard.2015.01.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363172PMC
April 2015

A Circulating Biomarker Risk-Prediction Model Correlates with CHADS-2 Risk Score in Chronic Atrial Fibrillation.

Authors:
Smita I Negi Ian Greener Aashish Anand Samuel C Dudley

IJC Metab Endocr 2015 Mar;6:24-26

Lifespan Cardiovascular Institute and the Warren Alpert Medical School of Brown University, Providence, RI.

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http://dx.doi.org/10.1016/j.ijcme.2015.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335707PMC
March 2015

Cardiac sodium channel mutations: why so many phenotypes?

Authors:
Man Liu Kai-Chien Yang Samuel C Dudley

Nat Rev Cardiol 2014 Oct 24;11(10):607-15. Epub 2014 Jun 24.

Warren Alpert Medical School, Brown University, 593 Eddy Street, APC730, Providence, RI 02903, USA.

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http://dx.doi.org/10.1038/nrcardio.2014.85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878851PMC
October 2014

Caveolin-1 modulates cardiac gap junction homeostasis and arrhythmogenecity by regulating cSrc tyrosine kinase.

Authors:
Kai-Chien Yang Cody A Rutledge Mao Mao Farnaz R Bakhshi An Xie Hong Liu Marcelo G Bonini Hemal H Patel Richard D Minshall Samuel C Dudley

Circ Arrhythm Electrophysiol 2014 Aug 13;7(4):701-10. Epub 2014 Jul 13.

From the Lifespan Cardiovascular Research Center, Department of Medicine, Warren Alpert School of Medicine, Brown University, Providence Veterans Administration Medical Center, RI (K.-C.Y., C.A.R., A.X., H.L., S.C.D.); Department of Medicine (K.-C.Y., C.A.R.), Department of Pharmacology (M.M., M.G.B., R.D.M.), and Department of Anesthesiology (F.R.B., R.D.M.), University of Illinois at Chicago; and Department of Anesthesiology, VA San Diego Healthcare Systems, University of California (H.H.P.).

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http://dx.doi.org/10.1161/CIRCEP.113.001394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198950PMC
August 2014

Targeting the unfolded protein response in heart diseases.

Authors:
Man Liu Samuel C Dudley

Expert Opin Ther Targets 2014 Jul 28;18(7):719-23. Epub 2014 May 28.

Brown University, Lifespan Cardiovascular Institute, The Providence VA Medical Center , Providence, RI , USA.

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http://dx.doi.org/10.1517/14728222.2014.918605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878849PMC
July 2014

Enhanced risk profiling of implanted defibrillator shocks with circulating SCN5A mRNA splicing variants: a pilot trial.

Authors:
Ge Gao Vikram Brahmanandam Mihai Raicu Lianzhi Gu Li Zhou Srinivasan Kasturirangan Anish Shah Smita I Negi Melissa R Wood Ankit A Desai Antone Tatooles Alan Schwartz Samuel C Dudley

J Am Coll Cardiol 2014 Jun 2;63(21):2261-9. Epub 2014 Apr 2.

Section of Cardiology and the Jesse Brown VAMC, University of Illinois at Chicago, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2014.02.588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096784PMC
June 2014

Mitochondria and arrhythmias.

Authors:
Kai-Chien Yang Marcelo G Bonini Samuel C Dudley

Free Radic Biol Med 2014 Jun 5;71:351-61. Epub 2014 Apr 5.

Lifespan Cardiovascular Institute, Providence VA Medical Center, and Brown University, Providence, RI 02903, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2014.03.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096785PMC
June 2014

c-Src kinase inhibition reduces arrhythmia inducibility and connexin43 dysregulation after myocardial infarction.

Authors:
Cody A Rutledge Fu Siong Ng Matthew S Sulkin Ian D Greener Artem M Sergeyenko Hong Liu Joanna Gemel Eric C Beyer Ali A Sovari Igor R Efimov Samuel C Dudley

J Am Coll Cardiol 2014 Mar 8;63(9):928-34. Epub 2014 Jan 8.

Lifespan Cardiovascular Institute, the Warren Alpert School of Medicine of Brown University, and the Providence Veterans Administration Medical Center, Providence. Rhode Island. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2013.10.081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963804PMC
March 2014

New diagnostic and therapeutic possibilities for diastolic heart failure.

Authors:
Euy-Myoung Jeong Samuel C Dudley

R I Med J (2013) 2014 Feb 3;97(2):35-7. Epub 2014 Feb 3.

Chief of Cardiology, The Miriam and Rhode Island Hospitals and Brown University; Director, Lifespan Cardiovascular Institute; and the Ruth and Paul Levinger Professor of Cardiology, The Warren Alpert Medical School of Brown University.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211876PMC
February 2014

Oxidative stress and atrial fibrillation: finding a missing piece to the puzzle.

Authors:
Kai-Chien Yang Samuel C Dudley

Circulation 2013 Oct 12;128(16):1724-6. Epub 2013 Sep 12.

Lifespan Cardiovascular Institute, the Warren Alpert School of Medicine, Brown University, and the Providence Veterans Administration Medical Center, Providence, RI.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.005837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909513PMC
October 2013

Unfolded protein response regulates cardiac sodium current in systolic human heart failure.

Authors:
Ge Gao An Xie Jianhua Zhang Amanda M Herman Euy-Myoung Jeong Lianzhi Gu Man Liu Kai-Chien Yang Timothy J Kamp Samuel C Dudley

Circ Arrhythm Electrophysiol 2013 Oct 13;6(5):1018-24. Epub 2013 Sep 13.

Lifespan Cardiovascular Research Center, the Warren Alpert School of Medicine, Brown University and Providence Veterans Administration Medical Center, Providence, RI.

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http://dx.doi.org/10.1161/CIRCEP.113.000274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909518PMC
October 2013

Mitochondria oxidative stress, connexin43 remodeling, and sudden arrhythmic death.

Authors:
Ali A Sovari Cody A Rutledge Euy-Myoung Jeong Elena Dolmatova Divya Arasu Hong Liu Nooshin Vahdani Lianzhi Gu Shadi Zandieh Lei Xiao Marcelo G Bonini Heather S Duffy Samuel C Dudley

Circ Arrhythm Electrophysiol 2013 Jun 4;6(3):623-31. Epub 2013 Apr 4.

Section of Cardiology and Center for Cardiovascular Research, University of Illinois at Chicago, IL, USA.

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http://dx.doi.org/10.1161/CIRCEP.112.976787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716298PMC
June 2013

Modulation of human mesenchymal stem cell function in a three-dimensional matrix promotes attenuation of adverse remodelling after myocardial infarction.

Authors:
David L Simpson Samuel C Dudley

J Tissue Eng Regen Med 2013 Mar 18;7(3):192-202. Epub 2011 Nov 18.

University of Illinois at Chicago, IL 60612, USA.

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http://dx.doi.org/10.1002/term.511DOI Listing
March 2013

Tetrahydrobiopterin improves diastolic dysfunction by reversing changes in myofilament properties.

Authors:
Euy-Myoung Jeong Michelle M Monasky Lianzhi Gu Domenico M Taglieri Bindiya G Patel Hong Liu Qiongying Wang Ian Greener Samuel C Dudley R John Solaro

J Mol Cell Cardiol 2013 Mar 14;56:44-54. Epub 2012 Dec 14.

Department of Medicine, Section of Cardiology, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2012.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666585PMC
March 2013

SCN5A splicing variants and the possibility of predicting heart failure-associated arrhythmia.

Authors:
Ge Gao Samuel C Dudley

Expert Rev Cardiovasc Ther 2013 Feb;11(2):117-9

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http://dx.doi.org/10.1586/erc.12.180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205156PMC
February 2013

RBM25/LUC7L3 function in cardiac sodium channel splicing regulation of human heart failure.

Authors:
Ge Gao Samuel C Dudley

Trends Cardiovasc Med 2013 Jan 31;23(1):5-8. Epub 2012 Aug 31.

Section of Cardiology, Department of Medicine, University of Illinois at Chicago and the Jesse Brown VA Medical Center, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1016/j.tcm.2012.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532530PMC
January 2013

Mitochondrial dysfunction causing cardiac sodium channel downregulation in cardiomyopathy.

Authors:
Man Liu Lianzhi Gu Matthew S Sulkin Hong Liu Euy-Myoung Jeong Ian Greener An Xie Igor R Efimov Samuel C Dudley

J Mol Cell Cardiol 2013 Jan 1;54:25-34. Epub 2012 Nov 1.

Section of Cardiology, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2012.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595554PMC
January 2013

Determination of ebselen-sensitive reactive oxygen metabolites (ebROM) in human serum based upon N,N'-diethyl-1,4-phenylenediamine oxidation.

Authors:
Yongliang Liang James R Roede Sergey Dikalov Nana Gletsu Miller Samuel C Dudley Arshed Quyyumi Dean P Jones

Clin Chim Acta 2012 Dec 8;414:1-6. Epub 2012 Jun 8.

Clinical Biomarkers Laboratory, Allergy and Critical Care Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, United States.

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http://dx.doi.org/10.1016/j.cca.2012.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662006PMC
December 2012

Association of low plasma adiponectin with early diastolic dysfunction.

Authors:
Smita I Negi Euy-Myoung Jeong Irfan Shukrullah Mihai Raicu Samuel C Dudley

Congest Heart Fail 2012 Jul-Aug;18(4):187-91. Epub 2012 Jan 9.

Section of Cardiology, University of Illinois at Chicago, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1111/j.1751-7133.2011.00276.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646250PMC
December 2012

Reactive oxygen species-targeted therapeutic interventions for atrial fibrillation.

Authors:
Ali A Sovari Samuel C Dudley

Front Physiol 2012 6;3:311. Epub 2012 Aug 6.

Section of Cardiology, Center for Cardiovascular Research, University of Illinois at Chicago Chicago, IL, USA.

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http://dx.doi.org/10.3389/fphys.2012.00311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429082PMC
October 2012

Angiotensin receptor type 1 single nucleotide polymorphism 1166A/C is associated with malignant arrhythmias and altered circulating miR-155 levels in patients with chronic heart failure.

Authors:
Raul R Blanco Harland Austin Richard N Vest Ravinder Valadri Wei Li Bernard Lassegue Qing Song Barry London Samuel C Dudley Heather L Bloom Charles D Searles A Maziar Zafari

J Card Fail 2012 Sep 9;18(9):717-23. Epub 2012 Aug 9.

Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1016/j.cardfail.2012.06.531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640363PMC
September 2012

Varicella-zoster virus (VZV) and alpha 1 antitrypsin: a fatal outcome in a patient affected by endemic pemphigus foliaceus.

Authors:
Ana Maria Abreu Velez Bruce R Smoller Weiqing Gao Hans E Grossniklaus Zhe Jiao Luis F Arias Samuel C Dudley Michael S Howard

Int J Dermatol 2012 Jul;51(7):809-16

Georgia Dermatopathology Associates, Atlanta, GA, USA.

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http://doi.wiley.com/10.1111/j.1365-4632.2011.05296.x
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http://dx.doi.org/10.1111/j.1365-4632.2011.05296.xDOI Listing
July 2012

Genetic variation in the alternative splicing regulator RBM20 is associated with dilated cardiomyopathy.

Authors:
Marwan M Refaat Steven A Lubitz Seiko Makino Zahid Islam J Michael Frangiskakis Haider Mehdi Rebecca Gutmann Michael L Zhang Heather L Bloom Calum A MacRae Samuel C Dudley Alaa A Shalaby Raul Weiss Dennis M McNamara Barry London Patrick T Ellinor

Heart Rhythm 2012 Mar 17;9(3):390-6. Epub 2011 Oct 17.

Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1016/j.hrthm.2011.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516872PMC
March 2012

Ranolazine improves cardiac diastolic dysfunction through modulation of myofilament calcium sensitivity.

Authors:
Joshua D Lovelock Michelle M Monasky Euy-Myoung Jeong Harvey A Lardin Hong Liu Bindiya G Patel Domenico M Taglieri Lianzhi Gu Praveen Kumar Narayan Pokhrel Dewan Zeng Luiz Belardinelli Dan Sorescu R John Solaro Samuel C Dudley

Circ Res 2012 Mar 16;110(6):841-50. Epub 2012 Feb 16.

Section of Cardiology, University of Illinois at Chicago, 60612, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.111.258251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314887PMC
March 2012

Metabolic stress, reactive oxygen species, and arrhythmia.

Authors:
Euy-Myoung Jeong Man Liu Megan Sturdy Ge Gao Susan T Varghese Ali A Sovari Samuel C Dudley

J Mol Cell Cardiol 2012 Feb 25;52(2):454-63. Epub 2011 Sep 25.

Section of Cardiology, University of Illinois at Chicago, Chicago, IL 60612, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00222828110042
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http://dx.doi.org/10.1016/j.yjmcc.2011.09.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264827PMC
February 2012

Use of human embryonic stem cell derived-mesenchymal cells for cardiac repair.

Authors:
David L Simpson Nolan L Boyd Sunjay Kaushal Steve L Stice Samuel C Dudley

Biotechnol Bioeng 2012 Jan 2;109(1):274-83. Epub 2011 Sep 2.

University of Illinois at Chicago/Jesse Brown VA Medical Center, 840 S. Wood Street, MC715, Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1002/bit.23301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220775PMC
January 2012

Cardiac autoantibodies from patients affected by a new variant of endemic pemphigus foliaceus in Colombia, South America.

Authors:
Ana Maria Abreu-Velez Michael S Howard Zhe Jiao Weiqing Gao Hong Yi Hans E Grossniklaus Mauricio Duque-Ramírez Samuel C Dudley

J Clin Immunol 2011 Dec 28;31(6):985-97. Epub 2011 Jul 28.

Georgia Dermatopathology Associates, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1007/s10875-011-9574-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380437PMC
December 2011

Inhibition of c-Src tyrosine kinase prevents angiotensin II-mediated connexin-43 remodeling and sudden cardiac death.

Authors:
Ali A Sovari Shahriar Iravanian Elena Dolmatova Zhe Jiao Hong Liu Shadi Zandieh Vibhash Kumar Kun Wang Kenneth E Bernstein Marcelo G Bonini Heather S Duffy Samuel C Dudley

J Am Coll Cardiol 2011 Nov;58(22):2332-9

Section of Cardiology and Center for Cardiovascular Research, University of Illinois at Chicago, 840 S.Wood Street, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1016/j.jacc.2011.07.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226807PMC
November 2011

Diastolic dysfunction is associated with cardiac fibrosis in the senescence-accelerated mouse.

Authors:
Alana L Reed Atsuko Tanaka Dan Sorescu Hong Liu Euy-Myoung Jeong Megan Sturdy Erik R Walp Samuel C Dudley Roy L Sutliff

Am J Physiol Heart Circ Physiol 2011 Sep 1;301(3):H824-31. Epub 2011 Jul 1.

Division of Pulmonary, Allergy and Critical Care Medicine, Emory University School of Medicine/Atlanta Veterans Affairs Medical Center, Atlanta, Georgia 30033, USA.

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http://dx.doi.org/10.1152/ajpheart.00407.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191096PMC
September 2011

Role of RBM25/LUC7L3 in abnormal cardiac sodium channel splicing regulation in human heart failure.

Authors:
Ge Gao An Xie Shu-Ching Huang Anyu Zhou Jianhua Zhang Amanda M Herman Sassan Ghassemzadeh Euy-Myoung Jeong Srinivasan Kasturirangan Mihai Raicu Michael A Sobieski Geetha Bhat Antone Tatooles Edward J Benz Timothy J Kamp Samuel C Dudley

Circulation 2011 Sep 22;124(10):1124-31. Epub 2011 Aug 22.

Section of Cardiology, University of Illinois at Chicago, 840 S Wood St, MC 715, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.111.044495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172047PMC
September 2011

Statins Decrease Oxidative Stress and ICD Therapies.

Authors:
Heather L Bloom Irfan Shukrullah Emir Veledar Rebecca Gutmann Barry London Samuel C Dudley

Cardiol Res Pract 2010 25;2010:253803. Epub 2010 Mar 25.

Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.

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https://www.hindawi.com/journals/crp/2010/253803/
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http://dx.doi.org/10.4061/2010/253803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847377PMC
July 2011

Inhibition of renin-angiotensin system (RAS) reduces ventricular tachycardia risk by altering connexin43.

Authors:
Shahriar Iravanian Ali A Sovari Harvey A Lardin Hong Liu Hong D Xiao Elena Dolmatova Zhe Jiao Brett S Harris Emily A Witham Robert G Gourdie Heather S Duffy Kenneth E Bernstein Samuel C Dudley

J Mol Med (Berl) 2011 Jul 7;89(7):677-87. Epub 2011 May 7.

Division of Cardiology, Atlanta Veterans Affairs Medical Center and Emory University, GA, 30033, USA.

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http://dx.doi.org/10.1007/s00109-011-0761-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156477PMC
July 2011

Effective antioxidant therapy for the management of arrhythmia.

Authors:
Ali A Sovari Marcelo G Bonini Samuel C Dudley

Expert Rev Cardiovasc Ther 2011 Jul;9(7):797-800

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http://dx.doi.org/10.1586/erc.11.85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208691PMC
July 2011

Statin therapy for the prevention of atrial fibrillation trial (SToP AF trial).

Authors:
Smita Negi Irfan Shukrullah Emir Veledar Heather L Bloom Dean P Jones Samuel C Dudley

J Cardiovasc Electrophysiol 2011 Apr 13;22(4):414-9. Epub 2010 Oct 13.

Section of Cardiology, University of Illinois at Chicago, Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1111/j.1540-8167.2010.01925.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022954PMC
April 2011

Ion channelopathies: a tapped-out mine?

Authors:
Samuel C Dudley

Am J Physiol Heart Circ Physiol 2011 Mar 30;300(3):H716-7. Epub 2010 Dec 30.

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http://www.physiology.org/doi/10.1152/ajpheart.01281.2010
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http://dx.doi.org/10.1152/ajpheart.01281.2010DOI Listing
March 2011

Characterization and functionality of cardiac progenitor cells in congenital heart patients.

Authors:
Rachana Mishra Kalpana Vijayan Evan J Colletti Daniel A Harrington Thomas S Matthiesen David Simpson Saik Kia Goh Brandon L Walker Graça Almeida-Porada Deli Wang Carl L Backer Samuel C Dudley Loren E Wold Sunjay Kaushal

Circulation 2011 Feb 17;123(4):364-73. Epub 2011 Jan 17.

Children's Memorial Hospital, Division of Cardiovascular-Thoracic Surgery, 2300 Children's Plaza, Chicago, IL 60614, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.110.971622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320857PMC
February 2011

Atrial fibrillation: the emerging role of inflammation and oxidative stress.

Authors:
Smita Negi Ali A Sovari Samuel C Dudley

Cardiovasc Hematol Disord Drug Targets 2010 Dec;10(4):262-8

University of Illinois at Chicago, 60612, USA.

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http://dx.doi.org/10.2174/187152910793743850DOI Listing
December 2010

The tail of the cardiac sodium channel.

Authors:
Lijuan L Shang Ge Gao Samuel C Dudley

Channels (Austin) 2008 May-Jun;2(3):161-2. Epub 2008 May 24.

Section of Cardiology, University of Illinois at Chicago, Chicago, Illinois 60612, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153466PMC
http://dx.doi.org/10.4161/chan.2.3.6189DOI Listing
October 2010

Reactive oxygen species originating from mitochondria regulate the cardiac sodium channel.

Authors:
Man Liu Hong Liu Samuel C Dudley

Circ Res 2010 Oct 19;107(8):967-74. Epub 2010 Aug 19.

Jr, Section of Cardiology, University of Illinois at Chicago/Jesse Brown VA Medical Center, 840 S Wood St, MC715, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.110.220673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955818PMC
October 2010

Using serum transforming growth factor-beta to predict myocardial fibrosis.

Authors:
Ali A Sovari Samuel C Dudley

Circ Res 2010 Mar;106(4):e3; author reply e4

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http://dx.doi.org/10.1161/CIRCRESAHA.109.215921DOI Listing
March 2010

Uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction.

Authors:
Gad A Silberman Tai-Hwang M Fan Hong Liu Zhe Jiao Hong D Xiao Joshua D Lovelock Beth M Boulden Julian Widder Scott Fredd Kenneth E Bernstein Beata M Wolska Sergey Dikalov David G Harrison Samuel C Dudley

Circulation 2010 Feb 18;121(4):519-28. Epub 2010 Jan 18.

Department of Medicine (Division of Cardiology), Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.109.883777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819317PMC
February 2010

Cardiac Na+ current regulation by pyridine nucleotides.

Authors:
Man Liu Shamarendra Sanyal Ge Gao Iman S Gurung Xiaodong Zhu Georgia Gaconnet Laurie J Kerchner Lijuan L Shang Christopher L-H Huang Andrew Grace Barry London Samuel C Dudley

Circ Res 2009 Oct 10;105(8):737-45. Epub 2009 Sep 10.

Division in Cardiology, University of Illinois at Chicago and the Jesse Brown Veteran Affairs Medical Center, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.109.197277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773656PMC
October 2009

Redox regulation, NF-kappaB, and atrial fibrillation.

Authors:
Ge Gao Samuel C Dudley

Antioxid Redox Signal 2009 Sep;11(9):2265-77

Section of Cardiology, University of Illinois at Chicago, and the Jesse Brown VA Medical Center, Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1089/ars.2009.2595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819799PMC
September 2009

Lost in translation: what is limiting cardiomyoplasty and can tissue engineering help?

Authors:
David Simpson Samuel C Dudley

Curr Stem Cell Res Ther 2009 Sep;4(3):210-23

Georgia Institute of Technology, Atlanta, GA 30332, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164232PMC
http://dx.doi.org/10.2174/157488809789057437DOI Listing
September 2009

Docking of mu-conotoxin GIIIA in the sodium channel outer vestibule.

Authors:
Gaurav Choudhary Marcela P Aliste D Peter Tieleman Robert J French Samuel C Dudley

Channels (Austin) 2007 Sep-Oct;1(5):344-52. Epub 2007 Oct 3.

Department of Medicine, Providence Veterans Affairs Medical Center/Brown University, Providence, Rhode Island 02904, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212855PMC
http://dx.doi.org/10.4161/chan.5112DOI Listing
November 2008

Sudden death in myotonic dystrophy.

Authors:
Ali A Sovari Samuel C Dudley

N Engl J Med 2008 Oct;359(15):1628; author reply 1328-9

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October 2008

Automated external cardioversion defibrillation monitoring in cardiac arrest: a randomized trial.

Authors:
Bakhtiar Ali Heather Bloom Emir Veledar Dorothy House Robert Norvel Samuel C Dudley A Maziar Zafari

Trials 2008 Jun 11;9:36. Epub 2008 Jun 11.

Atlanta Veterans Affairs Medical Center, Decatur, Georgia, USA.

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http://dx.doi.org/10.1186/1745-6215-9-36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440367PMC
June 2008

The renin-angiotensin-aldosterone system (RAAS) and cardiac arrhythmias.

Authors:
Shahriar Iravanian Samuel C Dudley

Heart Rhythm 2008 Jun 4;5(6 Suppl):S12-7. Epub 2008 Mar 4.

Division of Cardiology, Department of Medicine, Emory University, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1016/j.hrthm.2008.02.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600881PMC
June 2008

An imperfect syllogism: granulocyte colony-stimulating factor mobilization and cardiac regeneration.

Authors:
Samuel C Dudley David Simpson

J Am Coll Cardiol 2008 Apr;51(15):1438-9

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http://dx.doi.org/10.1016/j.jacc.2008.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153465PMC
April 2008

Time to defibrillation after in-hospital cardiac arrest.

Authors:
Bakhtiar Ali Samuel C Dudley A Maziar Zafari

N Engl J Med 2008 Apr;358(15):1632-3; author reply 1633-4

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April 2008

Prediction of atrial fibrillation following cardiac surgery using rough set derived rules.

Authors:
Matthew C Wiggins Hiram A Firpi Raul R Blanco Muhammad Amer Samuel C Dudley

Conf Proc IEEE Eng Med Biol Soc 2006 ;1:4006-9

Georgia Inst. of Technol., Atlanta, GA 30332, USA.

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http://dx.doi.org/10.1109/IEMBS.2006.259834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158652PMC
March 2008

NF-kappaB-dependent transcriptional regulation of the cardiac scn5a sodium channel by angiotensin II.

Authors:
Lijuan L Shang Shamarendra Sanyal Arnold E Pfahnl Zhe Jiao Jon Allen Hong Liu Samuel C Dudley

Am J Physiol Cell Physiol 2008 Jan 21;294(1):C372-9. Epub 2007 Nov 21.

Division of Cardiology, Department of Medicine, Emory University, Atlanta, Georgia, USA.

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http://www.physiology.org/doi/10.1152/ajpcell.00186.2007
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http://dx.doi.org/10.1152/ajpcell.00186.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150844PMC
January 2008

Speeding the recovery from ultraslow inactivation of voltage-gated Na+ channels by metal ion binding to the selectivity filter: a foot-on-the-door?

Authors:
Julia Szendroedi Walter Sandtner Touran Zarrabi Eva Zebedin Karlheinz Hilber Samuel C Dudley Harry A Fozzard Hannes Todt

Biophys J 2007 Dec 24;93(12):4209-24. Epub 2007 Aug 24.

Center for Biomolecular Medicine and Pharmacology, Institute of Pharmacology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1529/biophysj.107.104794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2098733PMC
December 2007

Human heart failure is associated with abnormal C-terminal splicing variants in the cardiac sodium channel.

Authors:
Lijuan L Shang Arnold E Pfahnl Shamarendra Sanyal Zhe Jiao Jon Allen Kathrin Banach John Fahrenbach Daiana Weiss W Robert Taylor A Maziar Zafari Samuel C Dudley

Circ Res 2007 Nov 27;101(11):1146-54. Epub 2007 Sep 27.

Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.107.152918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157752PMC
November 2007

Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias.

Authors:
Barry London Michael Michalec Haider Mehdi Xiaodong Zhu Laurie Kerchner Shamarendra Sanyal Prakash C Viswanathan Arnold E Pfahnl Lijuan L Shang Mohan Madhusudanan Catherine J Baty Stephen Lagana Ryan Aleong Rebecca Gutmann Michael J Ackerman Dennis M McNamara Raul Weiss Samuel C Dudley

Circulation 2007 Nov 29;116(20):2260-8. Epub 2007 Oct 29.

Cardiovascular Institute, University of Pittsburgh Medical Center, Scaife S-572, 200 Lothrop St, Pittsburgh, PA 15213-2582, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.107.703330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150966PMC
November 2007

A tissue engineering approach to progenitor cell delivery results in significant cell engraftment and improved myocardial remodeling.

Authors:
David Simpson Hong Liu Tai-Hwang Michael Fan Robert Nerem Samuel C Dudley

Stem Cells 2007 Sep 24;25(9):2350-7. Epub 2007 May 24.

Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1634/stemcells.2007-0132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158658PMC
September 2007

Oxidative stress markers are associated with persistent atrial fibrillation.

Authors:
Robert B Neuman Heather L Bloom Irfan Shukrullah Lyndsey A Darrow David Kleinbaum Dean P Jones Samuel C Dudley

Clin Chem 2007 Sep 28;53(9):1652-7. Epub 2007 Jun 28.

Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1373/clinchem.2006.083923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158654PMC
September 2007

Cardiac-restricted angiotensin-converting enzyme overexpression causes conduction defects and connexin dysregulation.

Authors:
Vijaykumar S Kasi Hong D Xiao Lijuan L Shang Shahriar Iravanian Jonathan Langberg Emily A Witham Zhe Jiao Carlos J Gallego Kenneth E Bernstein Samuel C Dudley

Am J Physiol Heart Circ Physiol 2007 Jul 2;293(1):H182-92. Epub 2007 Mar 2.

Division of Cardiology, Atlanta VA Medical Center, 1670 Clairmont Road, Atlanta, GA 30033, USA.

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http://www.physiology.org/doi/10.1152/ajpheart.00684.2006
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http://dx.doi.org/10.1152/ajpheart.00684.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160110PMC
July 2007

Long-term survival after successful inhospital cardiac arrest resuscitation.

Authors:
Heather L Bloom Irfan Shukrullah Jose R Cuellar Michael S Lloyd Samuel C Dudley A Maziar Zafari

Am Heart J 2007 May;153(5):831-6

Atlanta Veterans Affairs Medical Center, Decatur, GA 30033, USA.

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http://dx.doi.org/10.1016/j.ahj.2007.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156467PMC
May 2007

A sodium channel pore mutation causing Brugada syndrome.

Authors:
Arnold E Pfahnl Prakash C Viswanathan Raul Weiss Lijuan L Shang Shamarendra Sanyal Vladimir Shusterman Cari Kornblit Barry London Samuel C Dudley

Heart Rhythm 2007 Jan 28;4(1):46-53. Epub 2006 Sep 28.

Division of Cardiology, Atlanta Veterans Affairs Medical Center and Emory University, Atlanta, Georgia 30033, USA.

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http://dx.doi.org/10.1016/j.hrthm.2006.09.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779366PMC
January 2007

A possible mechanism of halocarbon-induced cardiac sensitization arrhythmias.

Authors:
Zhe Jiao Víctor R De Jesús Shahriar Iravanian Daniel P Campbell Jie Xu Juan A Vitali Kathrin Banach John Fahrenbach Samuel C Dudley

J Mol Cell Cardiol 2006 Oct 17;41(4):698-705. Epub 2006 Aug 17.

Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, and Atlanta Veterans Affairs Medical Center, Decatur, GA 30033, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2006.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169205PMC
October 2006

Early determinants of H2O2-induced endothelial dysfunction.

Authors:
Beth M Boulden Julian D Widder Jon C Allen Debra A Smith Ruaa N Al-Baldawi David G Harrison Sergey I Dikalov Hanjoong Jo Samuel C Dudley

Free Radic Biol Med 2006 Sep 3;41(5):810-7. Epub 2006 Jun 3.

Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30322, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S089158490600360
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http://dx.doi.org/10.1016/j.freeradbiomed.2006.05.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592456PMC
September 2006

Analysis of arrhythmic potential of embryonic stem cell-derived cardiomyocytes.

Authors:
Lijuan L Shang Samuel C Dudley Arnold E Pfahnl

Methods Mol Biol 2006 ;330:221-31

Division of Cardiology Atlanta, Emory University, Decatur, GA, USA.

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http://dx.doi.org/10.1385/1-59745-036-7:221DOI Listing
August 2006

Lipid-lowering drug use is associated with reduced prevalence of atrial fibrillation in patients with left ventricular systolic dysfunction.

Authors:
Ibrahim R Hanna Brent Heeke Heather Bush Lynne Brosius Diane King-Hageman Samuel C Dudley John F Beshai Jonathan J Langberg

Heart Rhythm 2006 Aug 9;3(8):881-6. Epub 2006 May 9.

Division of Cardiology, Section of Electrophysiology, Emory University, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1016/j.hrthm.2006.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164215PMC
August 2006

Rapid pacing of embryoid bodies impairs mitochondrial ATP synthesis by a calcium-dependent mechanism--a model of in vitro differentiated cardiomyocytes to study molecular effects of tachycardia.

Authors:
Lorenz Schild Alicja Bukowska Andreas Gardemann Pamela Polczyk Gerburg Keilhoff Michael Täger Samuel C Dudley Helmut U Klein Andreas Goette Uwe Lendeckel

Biochim Biophys Acta 2006 Jun 19;1762(6):608-15. Epub 2006 Apr 19.

Institute of Clinical Chemistry, Department of Pathobiochemistry, Otto-von-Guericke University Magdeburg, and Division of Cardiology, University Hospital Magdeburg, Germany.

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http://dx.doi.org/10.1016/j.bbadis.2006.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153943PMC
June 2006

The measurement of nitric oxide production by cultured endothelial cells.

Authors:
C Michael Hart Dean J Kleinhenz Sergey I Dikalov Beth M Boulden Samuel C Dudley

Methods Enzymol 2005 ;396:502-14

Department of Medicine, Emory University, Atlanta VA Medical Center, Decatur, Georgia 30033, USA.

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http://dx.doi.org/10.1016/S0076-6879(05)96042-4DOI Listing
January 2006

Atrial fibrillation increases production of superoxide by the left atrium and left atrial appendage: role of the NADPH and xanthine oxidases.

Authors:
Samuel C Dudley Nyssa E Hoch Louise A McCann Clegg Honeycutt Laura Diamandopoulos Tohru Fukai David G Harrison Sergey I Dikalov Jonathan Langberg

Circulation 2005 Aug;112(9):1266-73

Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.105.538108DOI Listing
August 2005

Beware of cells bearing gifts: cell replacement therapy and arrhythmic risk.

Authors:
Samuel C Dudley

Circ Res 2005 Jul;97(2):99-101

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http://dx.doi.org/10.1161/01.RES.00000175827.99824.7fDOI Listing
July 2005

Tandem promoters and developmentally regulated 5'- and 3'-mRNA untranslated regions of the mouse Scn5a cardiac sodium channel.

Authors:
Lijuan L Shang Samuel C Dudley

J Biol Chem 2005 Jan 14;280(2):933-40. Epub 2004 Oct 14.

Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1074/jbc.M409977200DOI Listing
January 2005

Lidocaine: a foot in the door of the inner vestibule prevents ultra-slow inactivation of a voltage-gated sodium channel.

Authors:
Walter Sandtner Julia Szendroedi Touran Zarrabi Eva Zebedin Karlheinz Hilber Ian Glaaser Harry A Fozzard Samuel C Dudley Hannes Todt

Mol Pharmacol 2004 Sep;66(3):648-57

Medical University of Vienna, Institute of Pharmacology, Währingerstrasse 13A, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1124/mol.66.3.DOI Listing
September 2004

Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death.

Authors:
Hong D Xiao Sebastien Fuchs Duncan J Campbell William Lewis Samuel C Dudley Vijaykumar S Kasi Brian D Hoit George Keshelava Hui Zhao Mario R Capecchi Kenneth E Bernstein

Am J Pathol 2004 Sep;165(3):1019-32

Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618615PMC
http://dx.doi.org/10.1016/S0002-9440(10)63363-9DOI Listing
September 2004

A program encouraging early defibrillation results in improved in-hospital resuscitation efficacy.

Authors:
A Maziar Zafari Susan K Zarter Vicki Heggen Patricia Wilson Regina A Taylor Kiran Reddy Andrea G Backscheider Samuel C Dudley

J Am Coll Cardiol 2004 Aug;44(4):846-52

Emory University School of Medicine, Department of Medicine, Division of Cardiology, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1016/j.jacc.2004.04.054DOI Listing
August 2004

Fatty acids differentially modulate insulin-stimulated endothelial nitric oxide production by an Akt-independent pathway.

Authors:
Matthew A Lynn Heidi L Rupnow Dean J Kleinhenz William A Kanner Samuel C Dudley C Michael Hart

J Investig Med 2004 Mar;52(2):129-36

Department ofMedicine, Veterans Affairs Medical Center, 151 -P 1670 Clairmont Rd, Decatur, GA 30033 , USA.

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http://dx.doi.org/10.1136/jim-52-02-22DOI Listing
March 2004

The structure of zetekitoxin AB, a saxitoxin analog from the Panamanian golden frog Atelopus zeteki: a potent sodium-channel blocker.

Authors:
Mari Yotsu-Yamashita Yong H Kim Samuel C Dudley Gaurav Choudhary Arnold Pfahnl Yasukatsu Oshima John W Daly

Proc Natl Acad Sci U S A 2004 Mar 22;101(13):4346-51. Epub 2004 Mar 22.

Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan.

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http://dx.doi.org/10.1073/pnas.0400368101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC384749PMC
March 2004