Samrat T Kundu

MBIP (MAP3K12 binding inhibitory protein) drives NSCLC metastasis by JNK-dependent activation of MMPs.

Authors:

Joshua Kapere Ochieng Samrat T Kundu Rakhee Bajaj B Leticia Rodriguez Jared J Fradette Don L Gibbons

Oncogene 2020 10 22;39(43):6719-6732. Epub 2020 Sep 22.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA.

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October 2020

IMPAD1 and KDELR2 drive invasion and metastasis by enhancing Golgi-mediated secretion.

Authors:

Rakhee Bajaj Samrat T Kundu Caitlin L Grzeskowiak Jared J Fradette Kenneth L Scott Chad J Creighton Don L Gibbons

Oncogene 2020 09 4;39(37):5979-5994. Epub 2020 Aug 4.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA.

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September 2020

SARS-CoV-2 infection induces EMT-like molecular changes, including ZEB1-mediated repression of the viral receptor ACE2, in lung cancer models.

bioRxiv 2020 May 29. Epub 2020 May 29.

Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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May 2020

ZEB1/NuRD complex suppresses TBC1D2b to stimulate E-cadherin internalization and promote metastasis in lung cancer.

Authors:

Roxsan Manshouri Etienne Coyaud Samrat T Kundu David H Peng Sabrina A Stratton Kendra Alton Rakhee Bajaj Jared J Fradette Rosalba Minelli Michael D Peoples Alessandro Carugo Fengju Chen Christopher Bristow Jeffrey J Kovacs Michelle C Barton Tim Heffernan Chad J Creighton Brian Raught Don L Gibbons

Nat Commun 2019 11 12;10(1):5125. Epub 2019 Nov 12.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.

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November 2019

ZEB1 suppression sensitizes KRAS mutant cancers to MEK inhibition by an IL17RD-dependent mechanism.

Authors:

David H Peng Samrat T Kundu Jared J Fradette Lixia Diao Pan Tong Lauren A Byers Jing Wang Jaime Rodriguez Canales Pamela A Villalobos Barbara Mino Yanan Yang Rosalba Minelli Michael D Peoples Christopher A Bristow Timothy P Heffernan Alessandro Carugo Ignacio I Wistuba Don L Gibbons

Sci Transl Med 2019 03;11(483)

Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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March 2019

TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins.

Authors:

Samrat T Kundu Caitlin L Grzeskowiak Jared J Fradette Laura A Gibson Leticia B Rodriguez Chad J Creighton Kenneth L Scott Don L Gibbons

Nat Commun 2018 07 16;9(1):2731. Epub 2018 Jul 16.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.

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July 2018

In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer.

Nat Commun 2018 07 16;9(1):2732. Epub 2018 Jul 16.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.

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July 2018

Dynamic variations in epithelial-to-mesenchymal transition (EMT), ATM, and SLFN11 govern response to PARP inhibitors and cisplatin in small cell lung cancer.

Oncotarget 2017 Apr;8(17):28575-28587

Department of Thoracic Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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April 2017

Plakophilin3 loss leads to an increase in PRL3 levels promoting K8 dephosphorylation, which is required for transformation and metastasis.

Authors:

Nileema Khapare Samrat T Kundu Lalit Sehgal Mugdha Sawant Rashmi Priya Prajakta Gosavi Neha Gupta Hunain Alam Madhura Karkhanis Nishigandha Naik Milind M Vaidya Sorab N Dalal

PLoS One 2012 6;7(6):e38561. Epub 2012 Jun 6.

Tata Memorial Centre, Kharghar Node, Navi Mumbai, Maharashtra, India.

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November 2012

KRAS alleles: the LCS6 3'UTR variant and KRAS coding sequence mutations in the NCI-60 panel.

Authors:

Samrat T Kundu Sunitha Nallur Trupti Paranjape Marta Boeke Joanne B Weidhaas Frank J Slack

Cell Cycle 2012 Jan 15;11(2):361-6. Epub 2012 Jan 15.

Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT, USA.

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January 2012

Novel function of keratins 5 and 14 in proliferation and differentiation of stratified epithelial cells.

Authors:

Hunain Alam Lalit Sehgal Samrat T Kundu Sorab N Dalal Milind M Vaidya

Mol Biol Cell 2011 Nov 7;22(21):4068-78. Epub 2011 Sep 7.

Advanced Centre for Treatment, Research & Education in Cancer, Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India.

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November 2011

Loss of keratins 8 and 18 leads to alterations in α6β4-integrin-mediated signalling and decreased neoplastic progression in an oral-tumour-derived cell line.

Authors:

Hunain Alam Samrat T Kundu Sorab N Dalal Milind M Vaidya

J Cell Sci 2011 Jun 24;124(Pt 12):2096-106. Epub 2011 May 24.

Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India.

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June 2011

E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly.

Authors:

Prajakta Gosavi Samrat T Kundu Nileema Khapare Lalit Sehgal Mansi S Karkhanis Sorab N Dalal

Cell Mol Life Sci 2011 Apr 23;68(8):1439-54. Epub 2010 Sep 23.

Advanced Centre for Treatment Research and Education in Cancer, Tata Memorial Centre, Kharghar Node, Navi Mumbai, India.

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April 2011

Robust and specific inhibition of microRNAs in Caenorhabditis elegans.

Authors:

Samrat T Kundu Frank J Slack

J Biol 2010 1;9(3):20. Epub 2010 Apr 1.

Department of Molecular, Cellular and Development Biology, Yale University, New Haven, CT 06520, USA.

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August 2010

A novel pocket in 14-3-3epsilon is required to mediate specific complex formation with cdc25C and to inhibit cell cycle progression upon activation of checkpoint pathways.

Authors:

Elphine Telles Amol S Hosing Samrat T Kundu Prasanna Venkatraman Sorab N Dalal

Exp Cell Res 2009 May 31;315(8):1448-57. Epub 2009 Jan 31.

KS215, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar Node, Navi Mumbai 410210, India.

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May 2009

14-3-3 Gamma is required to enforce both the incomplete S phase and G2 DNA damage checkpoints.

Authors:

Amol S Hosing Samrat T Kundu Sorab N Dalal

Cell Cycle 2008 Oct 21;7(20):3171-9. Epub 2008 Oct 21.

KS215, ACTREC, Advanced Centre for Treatment Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, India.

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October 2008

Plakophilin3 downregulation leads to a decrease in cell adhesion and promotes metastasis.

Authors:

Samrat T Kundu Prajakta Gosavi Nileema Khapare Rachana Patel Amol S Hosing Girish B Maru Arvind Ingle James A Decaprio Sorab N Dalal

Int J Cancer 2008 Nov;123(10):2303-14

ACTREC, Tata Memorial Centre, Kharghar Node, Navi Mumbai, India.

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November 2008

Publications by authors named "Samrat T Kundu"

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