Publications by authors named "Samir Messaoudi"

61Publications

Emerging Organometallic Methods for the Synthesis of C-Branched (Hetero)aryl, Alkenyl, and Alkyl Glycosides: C-H Functionalization and Dual Photoredox Approaches.

Chemistry 2020 Aug 19. Epub 2020 Aug 19.

Université Paris-Saclay, BioCIS, Faculté de Pharmacie, CNRS, 92290, Châtenay-Malabry, France.

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http://dx.doi.org/10.1002/chem.202003267DOI Listing
August 2020

Room-Temperature Pd-Catalyzed Synthesis of 1-(Hetero)aryl Selenoglycosides.

Org Lett 2020 08 6;22(16):6584-6589. Epub 2020 Aug 6.

BioCIS, Univ. Paris-Sud, CNRS, University Paris-Saclay, 92290 Châtenay-Malabry, France.

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http://dx.doi.org/10.1021/acs.orglett.0c02352DOI Listing
August 2020

Regio- and diastereoselective Pd-catalyzed synthesis of C2-aryl glycosides.

Chem Commun (Camb) 2020 Jun;56(52):7175-7178

Universite Paris-Saclay, CNRS, BioCIS, 92290, Châtenay-Malabry, France.

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http://dx.doi.org/10.1039/d0cc02175jDOI Listing
June 2020

Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency.

Eur J Med Chem 2020 Aug 5;199:112355. Epub 2020 May 5.

BioCIS, Equipe Labellisée Ligue Contre le Cancer, Univ. Paris-Sud, CNRS, University Paris-Saclay, F-92290, Châtenay Malabry, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2020.112355DOI Listing
August 2020

Synthesis of -Glycosyl-2-oxindoles by Pd-Catalyzed N-Arylation of 1-Amidosugars.

Org Lett 2020 06 13;22(11):4201-4206. Epub 2020 May 13.

Université Paris-Saclay, CNRS, BioCIS, 92290 Châtenay-Malabry, France.

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http://dx.doi.org/10.1021/acs.orglett.0c01262DOI Listing
June 2020

Electrochemical nickel-catalyzed Migita cross-coupling of 1-thiosugars with aryl, alkenyl and alkynyl bromides.

Chem Commun (Camb) 2020 Apr 20;56(32):4464-4467. Epub 2020 Mar 20.

BioCIS, Univ. Paris-Sud, CNRS, University Paris-Saclay, Châtenay-Malabry, France.

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http://dx.doi.org/10.1039/d0cc01126fDOI Listing
April 2020

Synthesis of 2,3-Substituted β--Glycosyl Indoles through C-H Activation/Annulation Process under Rh(III)-Catalysis.

Org Lett 2020 Jan 20;22(1):57-61. Epub 2019 Dec 20.

BioCIS, Univ. Paris-Sud, CNRS , University Paris-Saclay , Châtenay-Malabry , 92296 , France.

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http://dx.doi.org/10.1021/acs.orglett.9b03893DOI Listing
January 2020

Copper-Catalyzed Anomeric O-Arylation of Carbohydrate Derivatives at Room Temperature.

J Org Chem 2019 07 5;84(14):9226-9238. Epub 2019 Jul 5.

BioCIS , Univ. Paris-Sud, CNRS, University Paris-Saclay , 92290 Châtenay-Malabry , France.

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http://dx.doi.org/10.1021/acs.joc.9b01218DOI Listing
July 2019

Ni/Photoredox-Dual-Catalyzed Functionalization of 1-Thiosugars.

Org Lett 2019 07 18;21(13):5132-5137. Epub 2019 Jun 18.

BioCIS , Université Paris-Sud, CNRS, University Paris-Saclay , Châtenay-Malabry , France.

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http://dx.doi.org/10.1021/acs.orglett.9b01730DOI Listing
July 2019

Synthesis of aryl-thioglycopeptides through chemoselective Pd-mediated conjugation.

Chem Sci 2018 Dec 20;9(46):8753-8759. Epub 2018 Sep 20.

BioCIS , Univ. Paris-Sud , CNRS , Univ. Paris-Saclay , Châtenay-Malabry , France . Email: ; Tel: +33 0146835887.

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http://dx.doi.org/10.1039/c8sc02370kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295873PMC
December 2018

One-Pot Assembly of Unsymmetrical Biaryl Thioglycosides through Chemoselective Palladium-Catalyzed Three-Component Tandem Reaction.

Org Lett 2018 07 21;20(13):4067-4071. Epub 2018 Jun 21.

BioCIS, Univ. Paris-Sud, CNRS , University Paris-Saclay , Châtenay-Malabry , France.

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http://dx.doi.org/10.1021/acs.orglett.8b01624DOI Listing
July 2018

Antitumor activity of nanoliposomes encapsulating the novobiocin analog 6BrCaQ in a triple-negative breast cancer model in mice.

Cancer Lett 2018 09 5;432:103-111. Epub 2018 Jun 5.

Institut Galien Paris-Sud, CNRS, UMR 8612, LabEx LERMIT, Université Paris-Saclay, Faculté de Pharmacie, 5 Rue J.-B. Clément, Châtenay-Malabry, F-92296, France. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2018.06.001DOI Listing
September 2018

Conformational Ensemble and Biological Role of the TCTP Intrinsically Disordered Region: Influence of Calcium and Phosphorylation.

J Mol Biol 2018 05 30;430(11):1621-1639. Epub 2018 Apr 30.

BIOCIS, Université Paris-Sud, CNRS UMR 8076, Université Paris-Saclay, 5 rue Jean-Baptiste Clément, 92290 Châtenay-Malabry, France. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2018.04.024DOI Listing
May 2018

Convergent Synthesis of N,S-bis Glycosylquinolin-2-ones via a Pd-G3-XantPhos Precatalyst Catalysis.

Molecules 2018 Feb 26;23(3). Epub 2018 Feb 26.

BioCIS, Université Paris-Sud, CNRS, University Paris-Saclay, Châtenay-Malabry 92296, France.

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http://dx.doi.org/10.3390/molecules23030519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017768PMC
February 2018

Convergent Strategy to Dizocilpine MK-801 and Derivatives.

J Org Chem 2018 04 12;83(7):4264-4269. Epub 2018 Mar 12.

Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie , BioCIS, Univ. Paris-Sud, CNRS, University Paris-Saclay , Châtenay-Malabry , F-92296 , France.

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http://dx.doi.org/10.1021/acs.joc.8b00305DOI Listing
April 2018

Efficient Buchwald-Hartwig-Migita Cross-Coupling for DNA Thioglycoconjugation.

Chemistry 2018 Feb 16;24(8):1795-1800. Epub 2018 Jan 16.

BioCIS, Univ. Paris-Sud, CNRS, University Paris-Saclay, 92290, Châtenay-Malabry, France.

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http://dx.doi.org/10.1002/chem.201705371DOI Listing
February 2018

Controllable Activation of Pd-G3 Palladacycle Precatalyst in the Presence of Thiosugars: Rapid Access to 1-Aminobiphenyl Thioglycoside Atropoisomers at Room Temperature.

Chem Asian J 2017 Dec 21;12(24):3114-3118. Epub 2017 Nov 21.

BioCIS, Univ. Paris-Sud, CNRS, University Paris-Saclay, Châtenay-Malabry, France.

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http://dx.doi.org/10.1002/asia.201701415DOI Listing
December 2017

Intramolecular Pd-Catalyzed Anomeric C(sp)-H Activation of Glycosyl Carboxamides.

Org Lett 2017 10 13;19(19):5038-5041. Epub 2017 Sep 13.

BioCIS, Univ Paris-Sud, CNRS, University Paris-Saclay , Châtenay-Malabry, France.

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http://dx.doi.org/10.1021/acs.orglett.7b02170DOI Listing
October 2017

Synthesis of (1 → 2)-S-Linked Saccharides and S-Linked Glycoconjugates via a Palladium-G3-XantPhos Precatalyst Catalysis.

J Org Chem 2017 07 21;82(13):6720-6728. Epub 2017 Jun 21.

Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie, University of Paris-Sud, CNRS, BioCIS-UMR 8076 , 5 rue J.-B. Clément, Châtenay-Malabry F-92296, France.

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http://dx.doi.org/10.1021/acs.joc.7b00861DOI Listing
July 2017

Conversion of 3-Bromo-2H-coumarins to 3-(Benzofuran-2-yl)-2H-coumarins under Palladium Catalysis: Synthesis and Photophysical Properties Study.

Org Lett 2017 02 8;19(4):910-913. Epub 2017 Feb 8.

BioCIS, Université Paris-Sud, CNRS, University Paris-Saclay , Châtenay-Malabry 92296, France.

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http://dx.doi.org/10.1021/acs.orglett.7b00069DOI Listing
February 2017

Heat shock proteins and cancer: How can nanomedicine be harnessed?

J Control Release 2017 02 11;248:133-143. Epub 2017 Jan 11.

Institut Galien Paris-Sud, CNRS, UMR 8612, LabEx LERMIT, Univ. Paris-Sud/Univ. Paris-Saclay, 5 rue J.-B. Clément, Châtenay-Malabry, 92296, France. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2017.01.013DOI Listing
February 2017

Palladium-Mediated Labeling of Nucleic Acids.

Chembiochem 2017 03 14;18(5):426-431. Epub 2017 Feb 14.

Université Paris-Sud, CNRS, BioCIS-UMR 8076, Laboratoire CoSMIT, Equipe Labellisée Ligue Contre Le Cancer, LabEx LERMIT, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry, 92296, France.

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http://dx.doi.org/10.1002/cbic.201600599DOI Listing
March 2017

Stereoretentive Copper-Catalyzed Directed Thioglycosylation of C(sp )-H Bonds of Benzamides.

Chemistry 2016 Oct 25;22(42):15006-15010. Epub 2016 Aug 25.

BioCIS, Univ. Paris-Sud, CNRS, University Paris-Saclay, Châtenay-Malabry, France.

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http://dx.doi.org/10.1002/chem.201602909DOI Listing
October 2016

Palladium-Catalyzed Chemoselective and Biocompatible Functionalization of Cysteine-Containing Molecules at Room Temperature.

Chemistry 2016 Aug 30;22(32):11365-70. Epub 2016 Jun 30.

BioCIS, Equipe Labellisée Ligue Contre le Cancer, Univ. Paris-Sud, CNRS, University Paris-Saclay, 92296, Châtenay-Malabry, France.

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http://dx.doi.org/10.1002/chem.201602277DOI Listing
August 2016

Intramolecular Pd-Catalyzed Arylation of 1-Amidosugars: A New Route to N-Glycosyl Quinolin-2-ones.

Org Lett 2016 05 13;18(9):2126-9. Epub 2016 Apr 13.

BioCIS, Univ. Paris-Sud, CNRS, University Paris-Saclay , Châtenay-Malabry, France.

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http://dx.doi.org/10.1021/acs.orglett.6b00752DOI Listing
May 2016

Formulation and in vitro efficacy of liposomes containing the Hsp90 inhibitor 6BrCaQ in prostate cancer cells.

Int J Pharm 2016 Feb 22;499(1-2):101-109. Epub 2015 Dec 22.

Institut Galien Paris-Sud, CNRS, UMR 8612, Université Paris-Sud, Université Paris-Saclay, LabEx LERMIT, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry F-92296, France. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2015.12.053DOI Listing
February 2016

Synthesis of Biheterocycles Based on Quinolinone, Chromone, and Coumarin Scaffolds by Palladium-Catalyzed Decarboxylative Couplings.

J Org Chem 2016 Jan 28;81(2):424-32. Epub 2015 Dec 28.

Univ. Paris-Sud, CNRS, BioCIS-UMR 8076, Laboratoire de Chimie Thérapeutique, Equipe Labellisée Ligue Contre Le Cancer, LabEx LERMIT, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry, F-92296, France.

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http://dx.doi.org/10.1021/acs.joc.5b02103DOI Listing
January 2016

Diversity-oriented synthesis of fused thioglycosyl benzo[e][1,4]oxathiepin-5-ones and benzo[f][1,4]thiazepin-5(2H)-ones by a sequence of palladium-catalyzed glycosyl thiol arylation and deprotection-lactonization reactions.

Org Biomol Chem 2015 Nov 15;13(44):10904-16. Epub 2015 Sep 15.

Univ. Paris-Sud, CNRS, BioCIS-UMR 8076, Laboratoire de Chimie Thérapeutique, Equipe Labellisée Ligue Contre Le Cancer, LabEx LERMIT, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry, F-92296, France.

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http://dx.doi.org/10.1039/c5ob01603gDOI Listing
November 2015

IsoCombretaQuinazolines: Potent Cytotoxic Agents with Antitubulin Activity.

ChemMedChem 2015 Aug 15;10(8):1392-402. Epub 2015 Jun 15.

Univ. Paris-Sud, CNRS, BioCIS-UMR 8076, Laboratoire de Chimie Thérapeutique, Equipe Labellisée Ligue Contre le Cancer, LabEx LERMIT, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry, 92296 (France).

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http://dx.doi.org/10.1002/cmdc.201500069DOI Listing
August 2015

Stereoretentive palladium-catalyzed arylation, alkenylation, and alkynylation of 1-thiosugars and thiols using aminobiphenyl palladacycle precatalyst at room temperature.

Chemistry 2015 Jun 15;21(23):8375-9. Epub 2015 Apr 15.

Univ. Paris-Sud, CNRS, BioCIS-UMR 8076, Laboratoire de Chimie Thérapeutique, Equipe Labellisée Ligue Contre le Cancer, LabEx LERMIT Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry, 92296 (France).

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http://dx.doi.org/10.1002/chem.201501050DOI Listing
June 2015

Sulfinate derivatives: dual and versatile partners in organic synthesis.

Org Biomol Chem 2014 Dec;12(48):9743-59

Univ Paris Sud, CNRS, BioCIS UMR 8076, Laboratoire de Chimie Thérapeutique, Equipe Labellisée Ligue Contre le Cancer, LabEx LERMIT, Faculté de Pharmacie, 5 rue J-B Clément, Châtenay-Malabry, F-92296, France.

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http://dx.doi.org/10.1039/c4ob01727gDOI Listing
December 2014

A general Pd/Cu-catalyzed C-H heteroarylation of 3-bromoquinolin-2(1H)-ones.

Org Biomol Chem 2014 Nov;12(42):8533-41

Univ Paris-Sud, CNRS, BioCIS-UMR 8076, Laboratoire de Chimie Thérapeutique, Equipe Labellisée Ligue Contre le Cancer, LabEx LERMIT, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry, 92296, France.

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http://dx.doi.org/10.1039/c4ob01610fDOI Listing
November 2014

Synthesis and antiproliferative activity of novobiocin analogues as potential hsp90 inhibitors.

Eur J Med Chem 2014 Aug 28;83:498-507. Epub 2014 Jun 28.

University Paris-Sud, CNRS, BioCIS-UMR 8076, Laboratoire de Chimie Thérapeutique, Equipe Labellisée Ligue Contre Le Cancer, LabEx LERMIT, Faculté de Pharmacie, 5 Rue J.-B. Clément, Châtenay-Malabry F-92296, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2014.06.067DOI Listing
August 2014

Discovery of azaisoerianin derivatives as potential antitumors agents.

Eur J Med Chem 2014 May 13;78:178-89. Epub 2014 Mar 13.

Univ Paris-Sud, CNRS, BioCIS-UMR 8076, Laboratoire de Chimie Thérapeutique, LabEx LERMIT, Equipe Labellisée Ligue Contre le Cancer, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry F-92296, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2014.03.032DOI Listing
May 2014

Palladium(II)-catalyzed oxidative arylation of quinoxalin-2(1H)-ones with arylboronic acids.

Org Lett 2013 Nov 11;15(21):5606-9. Epub 2013 Oct 11.

Univ. Paris-Sud , CNRS, BioCIS-UMR 8076, LabEx LERMIT, Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry, 92296 France.

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http://dx.doi.org/10.1021/ol4028946DOI Listing
November 2013

Nickel-catalyzed arylation, alkenylation, and alkynylation of unprotected thioglycosides at room temperature.

Chemistry 2013 Nov 24;19(45):15276-80. Epub 2013 Sep 24.

Laboratoire de Chimie Thérapeutique, BioCIS-UMR 8076, LabEx LERMIT, Université Paris-Sud, CNRS, Faculté de Pharmacie, 5 rue J.-B. Clément, 92296 Châtenay-Malabry (France), Fax: (+33)146-83-58-28.

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http://dx.doi.org/10.1002/chem.201302999DOI Listing
November 2013

Stereoselective copper-catalyzed Chan-Lam-Evans N-arylation of glucosamines with arylboronic acids at room temperature.

Chem Commun (Camb) 2013 Sep;49(75):8359-61

Univ Paris-Sud, CNRS, BioCIS-UMR 8076, Laboratoire de Chimie Thérapeutique, LabEx LERMIT, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry, F-92296, France.

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http://dx.doi.org/10.1039/c3cc44780dDOI Listing
September 2013

A palladium-catalyzed coupling of 3-chloroquinoxalinones with various nitrogen-containing nucleophiles.

Org Biomol Chem 2013 Jun;11(23):3808-16

Université Paris-Sud, CNRS, BioCIS UMR 8076, Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry, F-92296, France.

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http://dx.doi.org/10.1039/c3ob40338fDOI Listing
June 2013

Synthesis and antikinetoplastid activities of 3-substituted quinolinones derivatives.

Eur J Med Chem 2012 Jun 16;52:44-50. Epub 2012 Mar 16.

Univ Paris-Sud, CNRS, BioCIS-UMR 8076, Laboratoire de Chimie Thérapeutique, LabEx LERMIT, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry, F-92296, France.

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http://dx.doi.org/10.1016/j.ejmech.2012.03.003DOI Listing
June 2012

Palladium-catalyzed decarboxylative coupling of quinolinone-3-carboxylic acids and related heterocyclic carboxylic acids with (hetero)aryl halides.

Org Lett 2012 Mar 1;14(6):1496-9. Epub 2012 Mar 1.

Université Paris-Sud, CNRS, BioCIS-UMR 8076, Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry, 92296 France.

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http://dx.doi.org/10.1021/ol300235kDOI Listing
March 2012

The metabolic fate of isocombretastatin A-4 in human liver microsomes: identification, synthesis and biological evaluation of metabolites.

ChemMedChem 2011 Oct 11;6(10):1781-8. Epub 2011 Jul 11.

Univ Paris-Sud, Faculté de Pharmacie, CNRS, BioCIS-UMR 8076, Laboratoire de Chimie Thérapeutique, 5 Rue J.-B. Clément, Châtenay-Malabry 92296, France.

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http://dx.doi.org/10.1002/cmdc.201100193DOI Listing
October 2011

Heat-shock protein 90 inhibitors as antitumor agents: a survey of the literature from 2005 to 2010.

Expert Opin Ther Pat 2011 Oct 21;21(10):1501-42. Epub 2011 Jun 21.

Univ Paris-Sud, CNRS, BioCIS-UMR 8076, Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry, F-92296, France.

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http://dx.doi.org/10.1517/13543776.2011.594041DOI Listing
October 2011

A general copper powder-catalyzed Ullmann-type reaction of 3-halo-4(1H)-quinolones with various nitrogen-containing nucleophiles.

J Org Chem 2011 Jun 13;76(12):4995-5005. Epub 2011 May 13.

1Univ Paris-Sud, 2CNRS, BioCIS UMR 8076, Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry, F-92296, France.

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http://dx.doi.org/10.1021/jo200680jDOI Listing
June 2011

Discovery and biological activity of 6BrCaQ as an inhibitor of the Hsp90 protein folding machinery.

ChemMedChem 2011 May 4;6(5):804-15. Epub 2011 Mar 4.

Université Paris-Sud, CNRS, BioCIS-UMR 8076, Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie, Châtenay-Malabry, France.

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http://dx.doi.org/10.1002/cmdc.201000489DOI Listing
May 2011

Discovery of isoerianin analogues as promising anticancer agents.

ChemMedChem 2011 Mar 14;6(3):488-97. Epub 2011 Jan 14.

Université Paris-Sud, CNRS, BioCIS-UMR 8076, Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie, 5 Rue J.-B. Clément, Châtenay-Malabry, 92296, France.

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http://dx.doi.org/10.1002/cmdc.201000456DOI Listing
March 2011

Assessing the chemical diversity of an hsp90 database.

Eur J Med Chem 2010 May 28;45(5):2000-9. Epub 2010 Jan 28.

University Paris-Sud, CNRS, BioCIS UMR 8076, Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry F-92296, France.

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http://dx.doi.org/10.1016/j.ejmech.2010.01.048DOI Listing
May 2010

A site selective C-H arylation of free-(NH2) adenines with aryl chlorides: application to the synthesis of 6,8-disubstituted adenines.

Org Biomol Chem 2009 Oct 14;7(20):4271-8. Epub 2009 Aug 14.

Université Paris-Sud, CNRS, BioCIS UMR 8076, Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry, F-92296, France.

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http://dx.doi.org/10.1039/b912033eDOI Listing
October 2009

Tosylcyclonovobiocic acids promote cleavage of the hsp90-associated cochaperone p23.

Biochem Biophys Res Commun 2009 Feb 30;379(2):514-8. Epub 2008 Dec 30.

Université Paris Sud, CNRS, UMR 8612, Laboratoire de Pharmacologie Cellulaire et Moléculaire des Anticancéreux, Faculté de Pharmacie, IFR 141, 5 rue J.-B. Clément, F-92296 Châtenay-Malabry, France.

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http://dx.doi.org/10.1016/j.bbrc.2008.12.102DOI Listing
February 2009

Antiproliferative and apoptotic activities of tosylcyclonovobiocic acids as potent heat shock protein 90 inhibitors in human cancer cells.

Cancer Lett 2009 Feb 7;274(1):88-94. Epub 2008 Oct 7.

Université Paris Sud, CNRS, UMR 8612, Laboratoire de Pharmacologie Cellulaire et Moléculaire des Anticancéreux, Faculté de Pharmacie, IFR 141, 5 rue Jean Baptiste Clément, F-92296 Châtenay-Malabry, France.

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http://dx.doi.org/10.1016/j.canlet.2008.09.001DOI Listing
February 2009

Pyrrolocarbazoles as checkpoint 1 kinase inhibitors.

Anticancer Agents Med Chem 2008 Aug;8(6):577-97

Laboratoire SEESIB, Université Blaise Pascal, UMR 6504 du CNRS, 24 Avenue des Landais, 63177 Aubière, France.

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August 2008

Synthesis and biological activity of simplified denoviose-coumarins related to novobiocin as potent inhibitors of heat-shock protein 90 (hsp90).

Bioorg Med Chem Lett 2008 Apr 14;18(7):2495-8. Epub 2008 Feb 14.

Univ Paris-Sud, CNRS, UMR 8612, Laboratoire de Pharmacologie Cellulaire et Moléculaire des Anticancéreux, Faculté de Pharmacie, IFR 141, 5 rue J.-B. Clément, Châtenay-Malabry F-92296, France.

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http://dx.doi.org/10.1016/j.bmcl.2008.01.128DOI Listing
April 2008

Bis-imide granulatimide analogues as potent Checkpoint 1 kinase inhibitors.

Eur J Pharmacol 2007 Jan 19;554(2-3):106-12. Epub 2006 Oct 19.

Laboratoire SEESIB, Université Blaise Pascal, UMR 6504 du CNRS, 63177 Aubière, France.

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http://linkinghub.elsevier.com/retrieve/pii/S001429990601148
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http://dx.doi.org/10.1016/j.ejphar.2006.10.022DOI Listing
January 2007

Synthesis and biological activities of 7-aza rebeccamycin analogues bearing the sugar moiety on the nitrogen of the pyridine ring.

Bioorg Med Chem 2006 Nov 4;14(22):7551-62. Epub 2006 Aug 4.

Université Blaise Pascal, Synthèse et Etude de Systèmes à Intérêt Biologique, UMR 6504 du CNRS, 63177 Aubière, France.

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http://dx.doi.org/10.1016/j.bmc.2006.07.013DOI Listing
November 2006

Synthesis and antiproliferative activities of diversely substituted glycosyl-isoindigo derivatives.

Eur J Med Chem 2006 Jan 5;41(1):88-100. Epub 2005 Dec 5.

Laboratoire SEESIB, Université Blaise-Pascal, UMR 6504 du CNRS, 24, avenue des Landais, 63177 Aubière, France.

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http://dx.doi.org/10.1016/j.ejmech.2005.10.004DOI Listing
January 2006

Synthesis and cytotoxicities of 7-aza rebeccamycin analogues bearing various substituents on the sugar moiety, on the imide nitrogen and on the carbazole framework.

Eur J Med Chem 2005 Oct;40(10):961-71

Université Blaise Pascal, Synthèse et Etude de Systèmes à Intérêt Biologique, UMR 6504 du CNRS, 63177 Aubière, France.

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http://dx.doi.org/10.1016/j.ejmech.2005.04.002DOI Listing
October 2005

Synthesis and biological evaluation of oxindoles and benzimidazolinones derivatives.

Eur J Med Chem 2004 May;39(5):453-8

Laboratoire SEESIB, Université Blaise Pascal, UMR 6504 du CNRS, 24, avenue des Landais, 63177 Aubière cedex, France.

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http://dx.doi.org/10.1016/j.ejmech.2004.01.001DOI Listing
May 2004