Publications by authors named "Samir M Hanash"

100Publications

Biomarkers for lung cancer screening and detection.

Cancer Epidemiol Biomarkers Prev 2020 Oct 22. Epub 2020 Oct 22.

Clinical Cancer Prevention, University of Texas MD Anderson Cancer Center.

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http://dx.doi.org/10.1158/1055-9965.EPI-20-0865DOI Listing
October 2020

Novel urinary protein biomarker panel for early diagnosis of gastric cancer.

Br J Cancer 2020 Sep 16. Epub 2020 Sep 16.

Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan.

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http://dx.doi.org/10.1038/s41416-020-01063-5DOI Listing
September 2020

Extracellular Vesicles Mediate B Cell Immune Response and Are a Potential Target for Cancer Therapy.

Cells 2020 06 22;9(6). Epub 2020 Jun 22.

Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.3390/cells9061518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349483PMC
June 2020

A Promising CPS1 Inhibitor Keeping Ammonia from Fueling Cancer.

Cell Chem Biol 2020 03;27(3):253-254

Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.chembiol.2020.03.002DOI Listing
March 2020

Development of autoantibody signatures for common cancers.

Semin Immunol 2020 02 8;47:101388. Epub 2020 Jan 8.

Department of Clinical Cancer Prevention, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.smim.2020.101388DOI Listing
February 2020

The BE GONE trial study protocol: a randomized crossover dietary intervention of dry beans targeting the gut microbiome of overweight and obese patients with a history of colorectal polyps or cancer.

BMC Cancer 2019 Dec 18;19(1):1233. Epub 2019 Dec 18.

Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1340, Houston, TX, TX 77030, USA.

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http://dx.doi.org/10.1186/s12885-019-6400-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921460PMC
December 2019

Measuring human carboxylesterase 2 activity in pancreatic cancer patient-derived xenografts using a ratiometric fluorescent chemosensor.

Chem Sci 2019 Sep 29;10(36):8428-8437. Epub 2019 Jul 29.

Department of Chemical and Physical Sciences , University of Toronto Mississauga , Mississauga , ON L5L 1C6 , Canada . Email:

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http://dx.doi.org/10.1039/c9sc00283aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844279PMC
September 2019

Failure to Disclose Potential Conflict of Interest-Letter of Explanation.

JAMA Oncol 2019 Nov 14. Epub 2019 Nov 14.

Aichi Cancer Center, Nagoya, Aichi, Japan.

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http://dx.doi.org/10.1001/jamaoncol.2019.5259DOI Listing
November 2019

Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes.

Cell 2019 08;178(4):795-806.e12

Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Clinical Cancer Genetics Program, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288240PMC
August 2019

Interconnected feedback loops among ESRP1, HAS2, and CD44 regulate epithelial-mesenchymal plasticity in cancer.

APL Bioeng 2018 Sep 22;2(3):031908. Epub 2018 Aug 22.

Department of Experimental Medicine I, Nikolaus-Fiebiger Center for Molecular Medicine, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen 91054, Germany.

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http://dx.doi.org/10.1063/1.5024874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324214PMC
September 2018

Whole Genome-Derived Tiled Peptide Arrays Detect Prediagnostic Autoantibody Signatures in Non-Small-Cell Lung Cancer.

Cancer Res 2019 04 5;79(7):1549-1557. Epub 2019 Feb 5.

Red and Charline McCombs Institute for the Early Detection and Treatment of Cancer, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-1536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445725PMC
April 2019

Targeting metabolic vulnerabilities of cancer: Small molecule inhibitors in clinic.

Cancer Rep (Hoboken) 2019 Feb 23;2(1):e1131. Epub 2018 Sep 23.

Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA.

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http://dx.doi.org/10.1002/cnr2.1131DOI Listing
February 2019

Testing the gene expression classification of the EMT spectrum.

Phys Biol 2019 01 18;16(2):025002. Epub 2019 Jan 18.

Center for Theoretical Biological Physics, Rice University, Houston, TX 77005, United States of America. Program in Systems, Synthetic and Physical Biology, Rice University, Houston, TX 77005, United States of America. These authors contributed equally.

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http://iopscience.iop.org/article/10.1088/1478-3975/aaf8d4
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http://dx.doi.org/10.1088/1478-3975/aaf8d4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179477PMC
January 2019

Blood based biomarkers beyond genomics for lung cancer screening.

Transl Lung Cancer Res 2018 Jun;7(3):327-335

Department of Clinical Cancer Prevention, MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.21037/tlcr.2018.05.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037962PMC
June 2018

HIV Infection and Circulating Levels of Prosurfactant Protein B and Surfactant Protein D.

J Infect Dis 2018 01;217(3):413-417

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland.

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http://dx.doi.org/10.1093/infdis/jix510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853828PMC
January 2018

Epithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding?

Mol Oncol 2017 07 19;11(7):739-754. Epub 2017 Jun 19.

Center for Theoretical Biological Physics, Rice University, Houston, TX, USA.

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http://dx.doi.org/10.1002/1878-0261.12084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496493PMC
July 2017

Lysyl Hydroxylase 2 Is Secreted by Tumor Cells and Can Modify Collagen in the Extracellular Space.

J Biol Chem 2016 Dec 1;291(50):25799-25808. Epub 2016 Nov 1.

From the Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas 77030,

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http://dx.doi.org/10.1074/jbc.M116.759803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207055PMC
December 2016

The Emerging Role of B Cells in Tumor Immunity.

Cancer Res 2016 10 15;76(19):5597-5601. Epub 2016 Sep 15.

The University of Texas M.D. Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-0431DOI Listing
October 2016

A statistical method for detecting differentially expressed SNVs based on next-generation RNA-seq data.

Biometrics 2017 03 8;73(1):42-51. Epub 2016 Jun 8.

Department of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, Texas, U.S.A.

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http://dx.doi.org/10.1111/biom.12548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5151178PMC
March 2017

EGFR Signaling Enhances Aerobic Glycolysis in Triple-Negative Breast Cancer Cells to Promote Tumor Growth and Immune Escape.

Cancer Res 2016 Mar 12;76(5):1284-96. Epub 2016 Jan 12.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Graduate School of Biomedical Sciences, The University of Texas Health Science Center at Houston, Houston, Texas. Graduate Institute of Cancer Biology and Center for Molecular Medicine, China Medical, University, Taichung, Taiwan. Department of Biotechnology, Asia University, Taichung, Taiwan.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-2478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775355PMC
March 2016

Cancer-Associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma.

Mol Cancer Res 2016 Mar 2;14(3):287-95. Epub 2015 Dec 2.

Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1541-7786.MCR-15-0307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794404PMC
March 2016

MAPRE1 as a plasma biomarker for early-stage colorectal cancer and adenomas.

Cancer Prev Res (Phila) 2015 Nov 4;8(11):1112-9. Epub 2015 Sep 4.

Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1940-6207.CAPR-15-0077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633385PMC
November 2015

Carboxylesterase 2 as a Determinant of Response to Irinotecan and Neoadjuvant FOLFIRINOX Therapy in Pancreatic Ductal Adenocarcinoma.

J Natl Cancer Inst 2015 Aug 29;107(8). Epub 2015 May 29.

: Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX (MC, HW, SMH); Fred Hutchinson Cancer Research Center, Seattle, WA (ML, IB); Departments of Surgical Oncology (MHK, JBF), Pathology (AM, HW, WT), and Translational Molecular Pathology (AM, HW, AT, SMH), The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1093/jnci/djv132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554193PMC
August 2015

Proteomic signatures associated with p53 mutational status in lung adenocarcinoma.

Proteomics 2014 Dec 20;14(23-24):2750-9. Epub 2014 Nov 20.

Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1002/pmic.201400378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403731PMC
December 2014

Modeling putative therapeutic implications of exosome exchange between tumor and immune cells.

Proc Natl Acad Sci U S A 2014 Oct 22;111(40):E4165-74. Epub 2014 Sep 22.

Center for Theoretical Biological Physics, Biosciences, Rice University, Houston, TX 77005-1827; School of Physics and Astronomy and The Sagol School of Neuroscience, Tel-Aviv University, Tel-Aviv 69978, Israel

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http://dx.doi.org/10.1073/pnas.1416745111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210007PMC
October 2014

Proteomic risk markers for coronary heart disease and stroke: validation and mediation of randomized trial hormone therapy effects on these diseases.

Genome Med 2013 27;5(12):112. Epub 2013 Dec 27.

Department of Clinical Cancer Prevention, Red and Charline McCombs Institute for the Early Detection and Treatment of Cancer, The University of Texas MD Anderson Cancer Center, 6767 Bertner Street, Houston, TX 77030, USA.

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http://dx.doi.org/10.1186/gm517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971342PMC
May 2014

Mouse to human blood-based cancer biomarker discovery strategies.

Cold Spring Harb Protoc 2014 Feb 1;2014(2):144-9. Epub 2014 Feb 1.

M.D. Anderson Cancer Center, Houston, Texas 77030.

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http://www.cshprotocols.org/lookup/doi/10.1101/pdb.top078808
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http://dx.doi.org/10.1101/pdb.top078808DOI Listing
February 2014

A novel soluble form of Tim-3 associated with severe graft-versus-host disease.

Biol Blood Marrow Transplant 2013 Sep 17;19(9):1323-30. Epub 2013 Jun 17.

Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA.

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http://dx.doi.org/10.1016/j.bbmt.2013.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966623PMC
September 2013

Enrichment strategies in glycomics-based lung cancer biomarker development.

Proteomics Clin Appl 2013 Oct 6;7(9-10):664-76. Epub 2013 Aug 6.

Division of Hematology and Oncology, University of California Davis Comprehensive Cancer Center, Sacramento, CA, USA.

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http://dx.doi.org/10.1002/prca.201200131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884000PMC
October 2013

Imaging a functional tumorigenic biomarker in the transformed epithelium.

Proc Natl Acad Sci U S A 2013 Jan 17;110(1):93-8. Epub 2012 Dec 17.

Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1073/pnas.1218694110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538269PMC
January 2013

Unleashing the power of proteomics to develop blood-based cancer markers.

Clin Chem 2013 Jan 24;59(1):119-26. Epub 2012 Oct 24.

Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://dx.doi.org/10.1373/clinchem.2012.184572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939937PMC
January 2013

Evaluation of known oncoantibodies, HER2, p53, and cyclin B1, in prediagnostic breast cancer sera.

Cancer Prev Res (Phila) 2012 Aug 19;5(8):1036-43. Epub 2012 Jun 19.

Tumor Vaccine Group, University of Washington, Box 358050, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-11-0558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790582PMC
August 2012

Concordant release of glycolysis proteins into the plasma preceding a diagnosis of ER+ breast cancer.

Cancer Res 2012 Apr 24;72(8):1935-42. Epub 2012 Feb 24.

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, School of Medicine, University of Washington, Seattle, Washington 98109, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066614PMC
April 2012

Microparticles from ovarian carcinomas are shed into ascites and promote cell migration.

Int J Gynecol Cancer 2012 May;22(4):546-52

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA, USA.

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http://dx.doi.org/10.1097/IGC.0b013e318241d9b9DOI Listing
May 2012

Increased plasma levels of the APC-interacting protein MAPRE1, LRG1, and IGFBP2 preceding a diagnosis of colorectal cancer in women.

Cancer Prev Res (Phila) 2012 Apr 25;5(4):655-64. Epub 2012 Jan 25.

Molecular Diagnostics Program, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-11-0412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419141PMC
April 2012

Why have protein biomarkers not reached the clinic?

Authors:
Samir M Hanash

Genome Med 2011 Oct 26;3(10):66. Epub 2011 Oct 26.

Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1186/gm282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239228PMC
October 2011

Emerging molecular biomarkers--blood-based strategies to detect and monitor cancer.

Nat Rev Clin Oncol 2011 Mar;8(3):142-50

Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, M5-C800, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1038/nrclinonc.2010.220DOI Listing
March 2011

Confounding effects of hormone replacement therapy in protein biomarker studies.

Cancer Epidemiol Biomarkers Prev 2011 Jan 29;20(1):134-9. Epub 2010 Oct 29.

Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-10-0673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317711PMC
January 2011

Towards an integrated proteomic and glycomic approach to finding cancer biomarkers.

Genome Med 2009 Jun 4;1(6):57. Epub 2009 Jun 4.

Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA.

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http://genomemedicine.biomedcentral.com/articles/10.1186/gm5
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http://dx.doi.org/10.1186/gm57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703866PMC
June 2009

In-depth proteomics to define the cell surface and secretome of ovarian cancer cells and processes of protein shedding.

Cancer Res 2009 Feb 20;69(3):728-30. Epub 2009 Jan 20.

Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-3087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720963PMC
February 2009

Identification of novel alternative splice isoforms of circulating proteins in a mouse model of human pancreatic cancer.

Cancer Res 2009 Jan;69(1):300-9

Center for Computational Medicine and Biology and Pediatric Endocrinology, University of Michigan, 100 Washtenaw Avenue, Palmer Commons, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613545PMC
January 2009

A bioinformatics tool for linking gene expression profiling results with public databases of microRNA target predictions.

RNA 2008 Nov 23;14(11):2290-6. Epub 2008 Sep 23.

The Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1261/rna.1188208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2578856PMC
November 2008

Identification of a Specific Vimentin Isoform That Induces an Antibody Response in Pancreatic Cancer.

Biomark Insights 2006 ;1:175-183

Departments of Pediatrics (SHH, DEM, HW, EP, RH, SMH), Pathology (TJG and JKG), Physiology (CDL), Surgery (DMS) and Internal Medicine (DEB), University of Michigan Medical School, 1150 W. Medical Center Drive, Ann Arbor, Michigan 48109 and the Department of Dental Microbiology (SHH), School of Dentistry, Kyungpook National University, 101 Dongin-Dong, Jung-Gu, Daegu, 700-422, South Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528299PMC
January 2006

Increased throughput and reduced carryover of mass spectrometry-based proteomics using a high-efficiency nonsplit nanoflow parallel dual-column capillary HPLC system.

J Proteome Res 2008 Jul 31;7(7):2743-55. Epub 2008 May 31.

Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.

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http://pubs.acs.org/doi/abs/10.1021/pr700876g
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http://dx.doi.org/10.1021/pr700876gDOI Listing
July 2008