Sami Heikkinen

Sami Heikkinen

UNVERIFIED PROFILE

Are you Sami Heikkinen?   Register this Author

Register author
Sami Heikkinen

Sami Heikkinen

Publications by authors named "Sami Heikkinen"

Are you Sami Heikkinen?   Register this Author

87Publications

1436Reads

9Profile Views

Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.

Authors:
Paul S de Vries Michael R Brown Amy R Bentley Yun J Sung Thomas W Winkler Ioanna Ntalla Karen Schwander Aldi T Kraja Xiuqing Guo Nora Franceschini Ching-Yu Cheng Xueling Sim Dina Vojinovic Jennifer E Huffman Solomon K Musani Changwei Li Mary F Feitosa Melissa A Richard Raymond Noordam Hugues Aschard Traci M Bartz Lawrence F Bielak Xuan Deng Rajkumar Dorajoo Kurt K Lohman Alisa K Manning Tuomo Rankinen Albert V Smith Salman M Tajuddin Evangelos Evangelou Mariaelisa Graff Maris Alver Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Ilaria Gandin Chuan Gao Anuj Goel Yanick Hagemeijer Sarah E Harris Fernando P Hartwig Meian He Andrea R V R Horimoto Fang-Chi Hsu Anne U Jackson Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Federica Laguzzi Joseph H Lee Jian'an Luan Leo-Pekka Lyytikäinen Nana Matoba Ilja M Nolte Maik Pietzner Muhammad Riaz M Abdullah Said Robert A Scott Tamar Sofer Alena Stančáková Fumihiko Takeuchi Bamidele O Tayo Peter J van der Most Tibor V Varga Yajuan Wang Erin B Ware Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Najaf Amin Marzyeh Amini Dan E Arking Tin Aung Christie Ballantyne Eric Boerwinkle Ulrich Broeckel Archie Campbell Mickaël Canouil Sabanayagam Charumathi Yii-Der Ida Chen John M Connell Ulf de Faire Lisa de Las Fuentes Renée de Mutsert H Janaka de Silva Jingzhong Ding Anna F Dominiczak Qing Duan Charles B Eaton Ruben N Eppinga Jessica D Faul Virginia Fisher Terrence Forrester Oscar H Franco Yechiel Friedlander Mohsen Ghanbari Franco Giulianini Hans J Grabe Megan L Grove C Charles Gu Tamara B Harris Sami Heikkinen Chew-Kiat Heng Makoto Hirata James E Hixson Barbara V Howard M Arfan Ikram David R Jacobs Craig Johnson Jost Bruno Jonas Candace M Kammerer Tomohiro Katsuya Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh Heikki A Koistinen Ivana Kolcic Charles Kooperberg Jose E Krieger Steve B Kritchevsky Michiaki Kubo Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Rozenn N Lemaitre Yize Li Jingjing Liang Jianjun Liu Kiang Liu Marie Loh Tin Louie Reedik Mägi Ani W Manichaikul Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Karen L Mohlke Thomas H Mosley Kenneth J Mukamal Mike A Nalls Matthias Nauck Christopher P Nelson Nona Sotoodehnia Jeff R O'Connell Nicholette D Palmer Raha Pazoki Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek Neil Poulter Leslie J Raffel Olli T Raitakari Alex P Reiner Treva K Rice Stephen S Rich Antonietta Robino Jennifer G Robinson Lynda M Rose Igor Rudan Carsten O Schmidt Pamela J Schreiner William R Scott Peter Sever Yuan Shi Stephen Sidney Mario Sims Blair H Smith Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Nicholas Tan Kent D Taylor Yik Ying Teo Yih Chung Tham André G Uitterlinden Diana van Heemst Dragana Vuckovic Melanie Waldenberger Lihua Wang Yujie Wang Zhe Wang Wen Bin Wei Christine Williams Gregory Wilson Mary K Wojczynski Jie Yao Bing Yu Caizheng Yu Jian-Min Yuan Wei Zhao Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Ian J Deary Tõnu Esko Martin Farrall Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo L Horta Yoichiro Kamatani Norihiro Kato Jaspal S Kooner Markku Laakso Karin Leander Terho Lehtimäki Patrik K E Magnusson Brenda Penninx Alexandre C Pereira Rainer Rauramaa Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Ya Xing Wang Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Wei Zheng Paul Elliott Kari E North Claude Bouchard Michele K Evans Vilmundur Gudnason Ching-Ti Liu Yongmei Liu Bruce M Psaty Paul M Ridker Rob M van Dam Sharon L R Kardia Xiaofeng Zhu Charles N Rotimi Dennis O Mook-Kanamori Myriam Fornage Tanika N Kelly Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Jingmin Liu Jerome I Rotter W James Gauderman Michael A Province Patricia B Munroe Kenneth Rice Daniel I Chasman L Adrienne Cupples Dabeeru C Rao Alanna C Morrison

Am J Epidemiol 2019 Jun;188(6):1033-1054

Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas.

View Article

Download full-text PDF

Source
https://academic.oup.com/aje/advance-article/doi/10.1093/aje
Publisher Site
http://dx.doi.org/10.1093/aje/kwz005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545280PMC
June 2019

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.

Authors:
Amy R Bentley Yun J Sung Michael R Brown Thomas W Winkler Aldi T Kraja Ioanna Ntalla Karen Schwander Daniel I Chasman Elise Lim Xuan Deng Xiuqing Guo Jingmin Liu Yingchang Lu Ching-Yu Cheng Xueling Sim Dina Vojinovic Jennifer E Huffman Solomon K Musani Changwei Li Mary F Feitosa Melissa A Richard Raymond Noordam Jenna Baker Guanjie Chen Hugues Aschard Traci M Bartz Jingzhong Ding Rajkumar Dorajoo Alisa K Manning Tuomo Rankinen Albert V Smith Salman M Tajuddin Wei Zhao Mariaelisa Graff Maris Alver Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Evangelos Evangelou Chuan Gao Anuj Goel Yanick Hagemeijer Sarah E Harris Fernando P Hartwig Meian He Andrea R V R Horimoto Fang-Chi Hsu Yi-Jen Hung Anne U Jackson Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Karin Leander Keng-Hung Lin Jian'an Luan Leo-Pekka Lyytikäinen Nana Matoba Ilja M Nolte Maik Pietzner Bram Prins Muhammad Riaz Antonietta Robino M Abdullah Said Nicole Schupf Robert A Scott Tamar Sofer Alena Stancáková Fumihiko Takeuchi Bamidele O Tayo Peter J van der Most Tibor V Varga Tzung-Dau Wang Yajuan Wang Erin B Ware Wanqing Wen Yong-Bing Xiang Lisa R Yanek Weihua Zhang Jing Hua Zhao Adebowale Adeyemo Saima Afaq Najaf Amin Marzyeh Amini Dan E Arking Zorayr Arzumanyan Tin Aung Christie Ballantyne R Graham Barr Lawrence F Bielak Eric Boerwinkle Erwin P Bottinger Ulrich Broeckel Morris Brown Brian E Cade Archie Campbell Mickaël Canouil Sabanayagam Charumathi Yii-Der Ida Chen Kaare Christensen Maria Pina Concas John M Connell Lisa de Las Fuentes H Janaka de Silva Paul S de Vries Ayo Doumatey Qing Duan Charles B Eaton Ruben N Eppinga Jessica D Faul James S Floyd Nita G Forouhi Terrence Forrester Yechiel Friedlander Ilaria Gandin He Gao Mohsen Ghanbari Sina A Gharib Bruna Gigante Franco Giulianini Hans J Grabe C Charles Gu Tamara B Harris Sami Heikkinen Chew-Kiat Heng Makoto Hirata James E Hixson M Arfan Ikram Yucheng Jia Roby Joehanes Craig Johnson Jost Bruno Jonas Anne E Justice Tomohiro Katsuya Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh Ivana Kolcic Charles Kooperberg Jose E Krieger Stephen B Kritchevsky Michiaki Kubo Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Jingjing Liang Shiow Lin Ching-Ti Liu Jianjun Liu Kiang Liu Marie Loh Kurt K Lohman Tin Louie Anna Luzzi Reedik Mägi Anubha Mahajan Ani W Manichaikul Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Karen L Mohlke Yukihide Momozawa Andrew P Morris Alison D Murray Mike A Nalls Matthias Nauck Christopher P Nelson Kari E North Jeffrey R O'Connell Nicholette D Palmer George J Papanicolau Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek Neil Poulter Olli T Raitakari Alex P Reiner Frida Renström Treva K Rice Stephen S Rich Jennifer G Robinson Lynda M Rose Frits R Rosendaal Igor Rudan Carsten O Schmidt Pamela J Schreiner William R Scott Peter Sever Yuan Shi Stephen Sidney Mario Sims Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Heather M Stringham Nicholas Y Q Tan Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham Henning Tiemeier Stephen T Turner André G Uitterlinden Diana van Heemst Melanie Waldenberger Heming Wang Lan Wang Lihua Wang Wen Bin Wei Christine A Williams Gregory Wilson Mary K Wojczynski Jie Yao Kristin Young Caizheng Yu Jian-Min Yuan Jie Zhou Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Richard S Cooper Ulf de Faire Ian J Deary Paul Elliott Tõnu Esko Martin Farrall Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo L Horta Jyh-Ming Jimmy Juang Yoichiro Kamatani Candace M Kammerer Norihiro Kato Jaspal S Kooner Markku Laakso Cathy C Laurie I-Te Lee Terho Lehtimäki Patrik K E Magnusson Albertine J Oldehinkel Brenda W J H Penninx Alexandre C Pereira Rainer Rauramaa Susan Redline Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Jun-Sing Wang Ya Xing Wang Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Eleftheria Zeggini Wei Zheng Claude Bouchard Michele K Evans Vilmundur Gudnason Sharon L R Kardia Yongmei Liu Bruce M Psaty Paul M Ridker Rob M van Dam Dennis O Mook-Kanamori Myriam Fornage Michael A Province Tanika N Kelly Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Ruth J F Loos Nora Franceschini Jerome I Rotter Xiaofeng Zhu Laura J Bierut W James Gauderman Kenneth Rice Patricia B Munroe Alanna C Morrison Dabeeru C Rao Charles N Rotimi L Adrienne Cupples

Nat Genet 2019 04 29;51(4):636-648. Epub 2019 Mar 29.

Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-019-0378-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467258PMC
April 2019

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.

Authors:
Yun Ju Sung Lisa de Las Fuentes Thomas W Winkler Daniel I Chasman Amy R Bentley Aldi T Kraja Ioanna Ntalla Helen R Warren Xiuqing Guo Karen Schwander Alisa K Manning Michael R Brown Hugues Aschard Mary F Feitosa Nora Franceschini Yingchang Lu Ching-Yu Cheng Xueling Sim Dina Vojinovic Jonathan Marten Solomon K Musani Tuomas O Kilpeläinen Melissa A Richard Stella Aslibekyan Traci M Bartz Rajkumar Dorajoo Changwei Li Yongmei Liu Tuomo Rankinen Albert Vernon Smith Salman M Tajuddin Bamidele O Tayo Wei Zhao Yanhua Zhou Nana Matoba Tamar Sofer Maris Alver Marzyeh Amini Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Ilaria Gandin Chuan Gao Franco Giulianini Anuj Goel Sarah E Harris Fernando P Hartwig Meian He Andrea R V R Horimoto Fang-Chi Hsu Anne U Jackson Candace M Kammerer Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Karin Leander Wen-Jane Lee Keng-Hung Lin Jian'an Luan Leo-Pekka Lyytikäinen Colin A McKenzie Christopher P Nelson Raymond Noordam Robert A Scott Wayne H H Sheu Alena Stančáková Fumihiko Takeuchi Peter J van der Most Tibor V Varga Robert J Waken Heming Wang Yajuan Wang Erin B Ware Stefan Weiss Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Tamuno Alfred Najaf Amin Dan E Arking Tin Aung R Graham Barr Lawrence F Bielak Eric Boerwinkle Erwin P Bottinger Peter S Braund Jennifer A Brody Ulrich Broeckel Brian Cade Archie Campbell Mickaël Canouil Aravinda Chakravarti Massimiliano Cocca Francis S Collins John M Connell Renée de Mutsert H Janaka de Silva Marcus Dörr Qing Duan Charles B Eaton Georg Ehret Evangelos Evangelou Jessica D Faul Nita G Forouhi Oscar H Franco Yechiel Friedlander He Gao Bruna Gigante C Charles Gu Preeti Gupta Saskia P Hagenaars Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Albert Hofman Barbara V Howard Steven C Hunt Marguerite R Irvin Yucheng Jia Tomohiro Katsuya Joel Kaufman Nicola D Kerrison Chiea Chuen Khor Woon-Puay Koh Heikki A Koistinen Charles B Kooperberg Jose E Krieger Michiaki Kubo Zoltan Kutalik Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Joseph H Lee Benjamin Lehne Daniel Levy Cora E Lewis Yize Li Sing Hui Lim Ching-Ti Liu Jianjun Liu Jingmin Liu Yeheng Liu Marie Loh Kurt K Lohman Tin Louie Reedik Mägi Koichi Matsuda Thomas Meitinger Andres Metspalu Lili Milani Yukihide Momozawa Thomas H Mosley Mike A Nalls Ubaydah Nasri Jeff R O'Connell Adesola Ogunniyi Walter R Palmas Nicholette D Palmer James S Pankow Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek David Porteous Olli T Raitakari Frida Renström Treva K Rice Paul M Ridker Antonietta Robino Jennifer G Robinson Lynda M Rose Igor Rudan Charumathi Sabanayagam Babatunde L Salako Kevin Sandow Carsten O Schmidt Pamela J Schreiner William R Scott Peter Sever Mario Sims Colleen M Sitlani Blair H Smith Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham André G Uitterlinden Melanie Waldenberger Lihua Wang Ya Xing Wang Wen Bin Wei Gregory Wilson Mary K Wojczynski Yong-Bing Xiang Jie Yao Jian-Min Yuan Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Yii-Der Ida Chen David R Weir Ulf de Faire Ian J Deary Tõnu Esko Martin Farrall Terrence Forrester Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo Lessa Horta Yi-Jen Hung Jost Bruno Jonas Norihiro Kato Jaspal S Kooner Markku Laakso Terho Lehtimäki Kae-Woei Liang Patrik K E Magnusson Albertine J Oldehinkel Alexandre C Pereira Thomas Perls Rainer Rauramaa Susan Redline Rainer Rettig Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Nicholas J Wareham Hugh Watkins Ananda R Wickremasinghe Tangchun Wu Yoichiro Kamatani Cathy C Laurie Claude Bouchard Richard S Cooper Michele K Evans Vilmundur Gudnason James Hixson Sharon L R Kardia Stephen B Kritchevsky Bruce M Psaty Rob M van Dam Donna K Arnett Dennis O Mook-Kanamori Myriam Fornage Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Ruth J F Loos Alex P Reiner Charles N Rotimi Laura J Bierut Xiaofeng Zhu L Adrienne Cupples Michael A Province Jerome I Rotter Paul W Franks Kenneth Rice Paul Elliott Mark J Caulfield W James Gauderman Patricia B Munroe Dabeeru C Rao Alanna C Morrison

Hum Mol Genet 2019 Apr 10. Epub 2019 Apr 10.

Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.

View Article

Download full-text PDF

Source
https://academic.oup.com/hmg/advance-article/doi/10.1093/hmg
Publisher Site
http://dx.doi.org/10.1093/hmg/ddz070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644157PMC
April 2019

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

Authors:
Mary F Feitosa Aldi T Kraja Daniel I Chasman Yun J Sung Thomas W Winkler Ioanna Ntalla Xiuqing Guo Nora Franceschini Ching-Yu Cheng Xueling Sim Dina Vojinovic Jonathan Marten Solomon K Musani Changwei Li Amy R Bentley Michael R Brown Karen Schwander Melissa A Richard Raymond Noordam Hugues Aschard Traci M Bartz Lawrence F Bielak Rajkumar Dorajoo Virginia Fisher Fernando P Hartwig Andrea R V R Horimoto Kurt K Lohman Alisa K Manning Tuomo Rankinen Albert V Smith Salman M Tajuddin Mary K Wojczynski Maris Alver Mathilde Boissel Qiuyin Cai Archie Campbell Jin Fang Chai Xu Chen Jasmin Divers Chuan Gao Anuj Goel Yanick Hagemeijer Sarah E Harris Meian He Fang-Chi Hsu Anne U Jackson Mika Kähönen Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Federica Laguzzi Jian'an Luan Nana Matoba Ilja M Nolte Sandosh Padmanabhan Muhammad Riaz Rico Rueedi Antonietta Robino M Abdullah Said Robert A Scott Tamar Sofer Alena Stančáková Fumihiko Takeuchi Bamidele O Tayo Peter J van der Most Tibor V Varga Veronique Vitart Yajuan Wang Erin B Ware Helen R Warren Stefan Weiss Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Najaf Amin Marzyeh Amini Dan E Arking Tin Aung Eric Boerwinkle Ingrid Borecki Ulrich Broeckel Morris Brown Marco Brumat Gregory L Burke Mickaël Canouil Aravinda Chakravarti Sabanayagam Charumathi Yii-Der Ida Chen John M Connell Adolfo Correa Lisa de Las Fuentes Renée de Mutsert H Janaka de Silva Xuan Deng Jingzhong Ding Qing Duan Charles B Eaton Georg Ehret Ruben N Eppinga Evangelos Evangelou Jessica D Faul Stephan B Felix Nita G Forouhi Terrence Forrester Oscar H Franco Yechiel Friedlander Ilaria Gandin He Gao Mohsen Ghanbari Bruna Gigante C Charles Gu Dongfeng Gu Saskia P Hagenaars Göran Hallmans Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Makoto Hirata Barbara V Howard M Arfan Ikram Ulrich John Tomohiro Katsuya Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh José E Krieger Stephen B Kritchevsky Michiaki Kubo Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Shiow Lin Jianjun Liu Jingmin Liu Marie Loh Tin Louie Reedik Mägi Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Karen L Mohlke Yukihide Momozawa Mike A Nalls Christopher P Nelson Nona Sotoodehnia Jill M Norris Jeff R O'Connell Nicholette D Palmer Thomas Perls Nancy L Pedersen Annette Peters Patricia A Peyser Neil Poulter Leslie J Raffel Olli T Raitakari Kathryn Roll Lynda M Rose Frits R Rosendaal Jerome I Rotter Carsten O Schmidt Pamela J Schreiner Nicole Schupf William R Scott Peter S Sever Yuan Shi Stephen Sidney Mario Sims Colleen M Sitlani Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Heather M Stringham Nicholas Y Q Tan Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham Stephen T Turner André G Uitterlinden Peter Vollenweider Melanie Waldenberger Lihua Wang Ya Xing Wang Wen Bin Wei Christine Williams Jie Yao Caizheng Yu Jian-Min Yuan Wei Zhao Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Ian J Deary Tõnu Esko Martin Farrall Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Jost Bruno Jonas Yoichiro Kamatani Norihiro Kato Jaspal S Kooner Zoltán Kutalik Markku Laakso Cathy C Laurie Karin Leander Terho Lehtimäki Lifelines Cohort Study Patrik K E Magnusson Albertine J Oldehinkel Brenda W J H Penninx Ozren Polasek David J Porteous Rainer Rauramaa Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Wei Zheng Claude Bouchard Kaare Christensen Michele K Evans Vilmundur Gudnason Bernardo L Horta Sharon L R Kardia Yongmei Liu Alexandre C Pereira Bruce M Psaty Paul M Ridker Rob M van Dam W James Gauderman Xiaofeng Zhu Dennis O Mook-Kanamori Myriam Fornage Charles N Rotimi L Adrienne Cupples Tanika N Kelly Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Charles Kooperberg Walter Palmas Kenneth Rice Alanna C Morrison Paul Elliott Mark J Caulfield Patricia B Munroe Dabeeru C Rao Michael A Province Daniel Levy

PLoS One 2018 18;13(6):e0198166. Epub 2018 Jun 18.

The Framingham Heart Study, Framingham, Massachusetts, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198166PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005576PMC
January 2019

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.

Authors:
Tuomas O Kilpeläinen Amy R Bentley Raymond Noordam Yun Ju Sung Karen Schwander Thomas W Winkler Hermina Jakupović Daniel I Chasman Alisa Manning Ioanna Ntalla Hugues Aschard Michael R Brown Lisa de Las Fuentes Nora Franceschini Xiuqing Guo Dina Vojinovic Stella Aslibekyan Mary F Feitosa Minjung Kho Solomon K Musani Melissa Richard Heming Wang Zhe Wang Traci M Bartz Lawrence F Bielak Archie Campbell Rajkumar Dorajoo Virginia Fisher Fernando P Hartwig Andrea R V R Horimoto Changwei Li Kurt K Lohman Jonathan Marten Xueling Sim Albert V Smith Salman M Tajuddin Maris Alver Marzyeh Amini Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Evangelos Evangelou Chuan Gao Mariaelisa Graff Sarah E Harris Meian He Fang-Chi Hsu Anne U Jackson Jing Hua Zhao Aldi T Kraja Brigitte Kühnel Federica Laguzzi Leo-Pekka Lyytikäinen Ilja M Nolte Rainer Rauramaa Muhammad Riaz Antonietta Robino Rico Rueedi Heather M Stringham Fumihiko Takeuchi Peter J van der Most Tibor V Varga Niek Verweij Erin B Ware Wanqing Wen Xiaoyin Li Lisa R Yanek Najaf Amin Donna K Arnett Eric Boerwinkle Marco Brumat Brian Cade Mickaël Canouil Yii-Der Ida Chen Maria Pina Concas John Connell Renée de Mutsert H Janaka de Silva Paul S de Vries Ayşe Demirkan Jingzhong Ding Charles B Eaton Jessica D Faul Yechiel Friedlander Kelley P Gabriel Mohsen Ghanbari Franco Giulianini Chi Charles Gu Dongfeng Gu Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Steven C Hunt M Arfan Ikram Jost B Jonas Woon-Puay Koh Pirjo Komulainen Jose E Krieger Stephen B Kritchevsky Zoltán Kutalik Johanna Kuusisto Carl D Langefeld Claudia Langenberg Lenore J Launer Karin Leander Rozenn N Lemaitre Cora E Lewis Jingjing Liang Jianjun Liu Reedik Mägi Ani Manichaikul Thomas Meitinger Andres Metspalu Yuri Milaneschi Karen L Mohlke Thomas H Mosley Alison D Murray Mike A Nalls Ei-Ei Khaing Nang Christopher P Nelson Sotoodehnia Nona Jill M Norris Chiamaka Vivian Nwuba Jeff O'Connell Nicholette D Palmer George J Papanicolau Raha Pazoki Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek David J Porteous Alaitz Poveda Olli T Raitakari Stephen S Rich Neil Risch Jennifer G Robinson Lynda M Rose Igor Rudan Pamela J Schreiner Robert A Scott Stephen S Sidney Mario Sims Jennifer A Smith Harold Snieder Tamar Sofer John M Starr Barbara Sternfeld Konstantin Strauch Hua Tang Kent D Taylor Michael Y Tsai Jaakko Tuomilehto André G Uitterlinden M Yldau van der Ende Diana van Heemst Trudy Voortman Melanie Waldenberger Patrik Wennberg Gregory Wilson Yong-Bing Xiang Jie Yao Caizheng Yu Jian-Min Yuan Wei Zhao Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden Ulf de Faire Ian J Deary Paul Elliott Tõnu Esko Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Norihiro Kato Markku Laakso Timo A Lakka Terho Lehtimäki Patrik K E Magnusson Albertine J Oldehinkel Brenda W J H Penninx Nilesh J Samani Xiao-Ou Shu Pim van der Harst Jana V Van Vliet-Ostaptchouk Peter Vollenweider Lynne E Wagenknecht Ya X Wang Nicholas J Wareham David R Weir Tangchun Wu Wei Zheng Xiaofeng Zhu Michele K Evans Paul W Franks Vilmundur Gudnason Caroline Hayward Bernardo L Horta Tanika N Kelly Yongmei Liu Kari E North Alexandre C Pereira Paul M Ridker E Shyong Tai Rob M van Dam Ervin R Fox Sharon L R Kardia Ching-Ti Liu Dennis O Mook-Kanamori Michael A Province Susan Redline Cornelia M van Duijn Jerome I Rotter Charles B Kooperberg W James Gauderman Bruce M Psaty Kenneth Rice Patricia B Munroe Myriam Fornage L Adrienne Cupples Charles N Rotimi Alanna C Morrison Dabeeru C Rao Ruth J F Loos

Nat Commun 2019 01 22;10(1):376. Epub 2019 Jan 22.

Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized Medicine, New York, 10029, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-018-08008-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342931PMC
January 2019

On the Mechanism of the Reactivity of 1,3-Dialkylimidazolium Salts under Basic to Acidic Conditions: A Combined Kinetic and Computational Study.

Angew Chem Int Ed Engl 2018 Sep 31;57(36):11613-11617. Epub 2018 Jul 31.

Department of Chemistry, University of Helsinki, P.O. Box 55, A.I. Virtasen aukio 1, 00014, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/anie.201805016DOI Listing
September 2018

Liquid-State NMR Analysis of Nanocelluloses.

Biomacromolecules 2018 07 11;19(7):2708-2720. Epub 2018 Apr 11.

Materials Chemistry Division, Chemistry Department , University of Helsinki , AI Virtasen Aukio 1 , Helsinki , Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.biomac.8b00295DOI Listing
July 2018

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.

Authors:
Yun J Sung Thomas W Winkler Lisa de Las Fuentes Amy R Bentley Michael R Brown Aldi T Kraja Karen Schwander Ioanna Ntalla Xiuqing Guo Nora Franceschini Yingchang Lu Ching-Yu Cheng Xueling Sim Dina Vojinovic Jonathan Marten Solomon K Musani Changwei Li Mary F Feitosa Tuomas O Kilpeläinen Melissa A Richard Raymond Noordam Stella Aslibekyan Hugues Aschard Traci M Bartz Rajkumar Dorajoo Yongmei Liu Alisa K Manning Tuomo Rankinen Albert Vernon Smith Salman M Tajuddin Bamidele O Tayo Helen R Warren Wei Zhao Yanhua Zhou Nana Matoba Tamar Sofer Maris Alver Marzyeh Amini Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Ilaria Gandin Chuan Gao Franco Giulianini Anuj Goel Sarah E Harris Fernando Pires Hartwig Andrea R V R Horimoto Fang-Chi Hsu Anne U Jackson Mika Kähönen Anuradhani Kasturiratne Brigitte Kühnel Karin Leander Wen-Jane Lee Keng-Hung Lin Jian 'an Luan Colin A McKenzie He Meian Christopher P Nelson Rainer Rauramaa Nicole Schupf Robert A Scott Wayne H H Sheu Alena Stančáková Fumihiko Takeuchi Peter J van der Most Tibor V Varga Heming Wang Yajuan Wang Erin B Ware Stefan Weiss Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Tamuno Alfred Najaf Amin Dan Arking Tin Aung R Graham Barr Lawrence F Bielak Eric Boerwinkle Erwin P Bottinger Peter S Braund Jennifer A Brody Ulrich Broeckel Claudia P Cabrera Brian Cade Yu Caizheng Archie Campbell Mickaël Canouil Aravinda Chakravarti Ganesh Chauhan Kaare Christensen Massimiliano Cocca Francis S Collins John M Connell Renée de Mutsert H Janaka de Silva Stephanie Debette Marcus Dörr Qing Duan Charles B Eaton Georg Ehret Evangelos Evangelou Jessica D Faul Virginia A Fisher Nita G Forouhi Oscar H Franco Yechiel Friedlander He Gao Bruna Gigante Misa Graff C Charles Gu Dongfeng Gu Preeti Gupta Saskia P Hagenaars Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Makoto Hirata Albert Hofman Barbara V Howard Steven Hunt Marguerite R Irvin Yucheng Jia Roby Joehanes Anne E Justice Tomohiro Katsuya Joel Kaufman Nicola D Kerrison Chiea Chuen Khor Woon-Puay Koh Heikki A Koistinen Pirjo Komulainen Charles Kooperberg Jose E Krieger Michiaki Kubo Johanna Kuusisto Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Sing Hui Lim Shiow Lin Ching-Ti Liu Jianjun Liu Jingmin Liu Kiang Liu Yeheng Liu Marie Loh Kurt K Lohman Jirong Long Tin Louie Reedik Mägi Anubha Mahajan Thomas Meitinger Andres Metspalu Lili Milani Yukihide Momozawa Andrew P Morris Thomas H Mosley Peter Munson Alison D Murray Mike A Nalls Ubaydah Nasri Jill M Norris Kari North Adesola Ogunniyi Sandosh Padmanabhan Walter R Palmas Nicholette D Palmer James S Pankow Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek Olli T Raitakari Frida Renström Treva K Rice Paul M Ridker Antonietta Robino Jennifer G Robinson Lynda M Rose Igor Rudan Charumathi Sabanayagam Babatunde L Salako Kevin Sandow Carsten O Schmidt Pamela J Schreiner William R Scott Sudha Seshadri Peter Sever Colleen M Sitlani Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham André G Uitterlinden Melanie Waldenberger Lihua Wang Ya X Wang Wen Bin Wei Christine Williams Gregory Wilson Mary K Wojczynski Jie Yao Jian-Min Yuan Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Yii-Der Ida Chen Ulf de Faire Ian J Deary Tõnu Esko Martin Farrall Terrence Forrester Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo Lessa Horta Yi-Jen Hung Jost B Jonas Norihiro Kato Jaspal S Kooner Markku Laakso Terho Lehtimäki Kae-Woei Liang Patrik K E Magnusson Anne B Newman Albertine J Oldehinkel Alexandre C Pereira Susan Redline Rainer Rettig Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Wei Zheng Yoichiro Kamatani Cathy C Laurie Claude Bouchard Richard S Cooper Michele K Evans Vilmundur Gudnason Sharon L R Kardia Stephen B Kritchevsky Daniel Levy Jeff R O'Connell Bruce M Psaty Rob M van Dam Mario Sims Donna K Arnett Dennis O Mook-Kanamori Tanika N Kelly Ervin R Fox Caroline Hayward Myriam Fornage Charles N Rotimi Michael A Province Cornelia M van Duijn E Shyong Tai Tien Yin Wong Ruth J F Loos Alex P Reiner Jerome I Rotter Xiaofeng Zhu Laura J Bierut W James Gauderman Mark J Caulfield Paul Elliott Kenneth Rice Patricia B Munroe Alanna C Morrison L Adrienne Cupples Dabeeru C Rao Daniel I Chasman

Am J Hum Genet 2018 03 15;102(3):375-400. Epub 2018 Feb 15.

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2018.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985266PMC
March 2018

ME-CAGEBIRD-CPMG-HSQMBC. A phase sensitive, multiplicity edited long range HSQC with absorptive line shapes.

J Magn Reson 2016 11 17;272:114-122. Epub 2016 Sep 17.

Department of Chemistry, University of Helsinki, P.O. Box 55, FIN-00014 Helsinki, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmr.2016.09.012DOI Listing
November 2016

Quantitative, equal carbon response HSQC experiment, QEC-HSQC.

J Magn Reson 2016 10 9;271:34-9. Epub 2016 Aug 9.

Laboratory of Organic Chemistry, Department of Chemistry, University of Helsinki, P.O. Box 55, FI-00014 University of Helsinki, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmr.2016.08.003DOI Listing
October 2016

The Reactivity of Thymine and Thymidine 5,6-Epoxides with Organometallic Reagents - A Route to Thymidine (6-4) Photoproduct Analogues.

J Org Chem 2016 05 22;81(9):3848-59. Epub 2016 Apr 22.

Department of Chemistry, †Laboratory of Inorganic Chemistry and ‡Laboratory of Organic Chemistry, University of Helsinki , P.O. Box 55, Helsinki FIN-00014, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.joc.6b00495DOI Listing
May 2016

The Effects of Sequence Variation on Genome-wide NRF2 Binding--New Target Genes and Regulatory SNPs.

Nucleic Acids Res 2016 Feb 29;44(4):1760-75. Epub 2016 Jan 29.

Department of Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, FIN-70211 Kuopio, Finland

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkw052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770247PMC
February 2016

Synthesis and applications of secondary amine derivatives of (+)-dehydroabietylamine in chiral molecular recognition.

Org Biomol Chem 2015 Nov 4;13(42):10548-55. Epub 2015 Sep 4.

Department of Chemistry, University of Helsinki, A.I. Virtasen aukio 1, P.O. Box 55, FI-00014 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c5ob01667cDOI Listing
November 2015

Diverting Hydrogenations with Wilkinson's Catalyst towards Highly Reactive Rhodium(I) Species.

Angew Chem Int Ed Engl 2015 Nov 6;54(48):14321-5. Epub 2015 Oct 6.

Department of Chemistry, P.O.Box 55, 00014 University of Helsinki (Finland).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/anie.201506216DOI Listing
November 2015

Synthesis of Tertiary and Quaternary Amine Derivatives from Wood Resin as Chiral NMR Solvating Agents.

Molecules 2015 Nov 23;20(11):20873-86. Epub 2015 Nov 23.

Department of Chemistry, University of Helsinki, A.I. Virtasen aukio 1, P. O. Box 55, FI-00014, Helsinki 00100, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules201119732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332576PMC
November 2015

The transcriptional regulator BCL6 participates in the secondary gene regulatory response to vitamin D.

Biochim Biophys Acta 2015 Mar 5;1849(3):300-8. Epub 2014 Dec 5.

School of Medicine, Institute of Biomedicine, University of Eastern Finland, FI-70211 Kuopio, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbagrm.2014.12.001DOI Listing
March 2015

Gene expression mapping of histone deacetylases and co-factors, and correlation with survival time and 1H-HRMAS metabolomic profile in human gliomas.

Sci Rep 2015 Mar 20;5:9087. Epub 2015 Mar 20.

1] Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC)/CNRS UMR 7104/INSERM U 964/Université de Strasbourg, 1 rue Laurent Fries, 67404 Illkirch, France [2] Institut Clinique de la Souris, 1 rue Laurent Fries, 67404 Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep09087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367156PMC
March 2015

Data quality in fMRI and simultaneous EEG-fMRI.

MAGMA 2015 Feb 26;28(1):23-31. Epub 2014 Apr 26.

HUS Medical Imaging Center, P.O. Box 340, 00029 HUS,, Helsinki, Finland,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10334-014-0443-6DOI Listing
February 2015

Patterns of genome-wide VDR locations.

PLoS One 2014 30;9(4):e96105. Epub 2014 Apr 30.

Department of Biosciences, University of Eastern Finland, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0096105PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005760PMC
January 2015

The mechanisms of genome-wide target gene regulation by TCF7L2 in liver cells.

Nucleic Acids Res 2014 Dec 20;42(22):13646-61. Epub 2014 Nov 20.

Institute of Biomedicine, University of Eastern Finland, Kuopio 70211, Finland

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gku1225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267646PMC
December 2014

Capricious selectivity in electrophilic deuteration of methylenedioxy substituted aromatic compounds.

J Org Chem 2014 Nov 13;79(21):10636-40. Epub 2014 Oct 13.

Department of Chemistry, University of Helsinki , P.O. Box 55, FIN-00014 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/jo5019427
Publisher Site
http://dx.doi.org/10.1021/jo5019427DOI Listing
November 2014

SUMOylation modulates the transcriptional activity of androgen receptor in a target gene and pathway selective manner.

Nucleic Acids Res 2014 Jul 30;42(13):8310-9. Epub 2014 Jun 30.

Institute of Biomedicine, University of Eastern Finland, Kuopio, PO Box 1627, FI-70211 Kuopio, Finland Department of Pathology, Kuopio University Hospital, Kuopio, Finland

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gku543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117771PMC
July 2014

Challenges in analysis of high-molar mass dextrans: comparison of HPSEC, AsFlFFF and DOSY NMR spectroscopy.

Carbohydr Polym 2014 Jan 21;99:199-207. Epub 2013 Aug 21.

Department of Food and Environmental Sciences, P.O. Box 27, FIN-00014 University of Helsinki, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.carbpol.2013.08.021DOI Listing
January 2014

Dynamics of 1α,25-dihydroxyvitamin D3-dependent chromatin accessibility of early vitamin D receptor target genes.

Biochim Biophys Acta 2013 Dec 1;1829(12):1266-75. Epub 2013 Nov 1.

School of Medicine, Institute of Biomedicine, University of Eastern Finland, FIN-70211 Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbagrm.2013.10.003DOI Listing
December 2013

The gene for the transcription factor BHLHE40/DEC1/stra13 is a dynamically regulated primary target of the vitamin D receptor.

J Steroid Biochem Mol Biol 2013 Jul 7;136:62-7. Epub 2012 Dec 7.

School of Medicine, Institute of Biomedicine, University of Eastern Finland, FIN-70210 Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jsbmb.2012.11.011DOI Listing
July 2013

Chromatin acetylation at transcription start sites and vitamin D receptor binding regions relates to effects of 1α,25-dihydroxyvitamin D3 and histone deacetylase inhibitors on gene expression.

Nucleic Acids Res 2013 Jan 23;41(1):110-24. Epub 2012 Oct 23.

School of Medicine, Institute of Biomedicine, University of Eastern Finland, FIN-70210 Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gks959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592476PMC
January 2013

The activation of hepatic and muscle polyamine catabolism improves glucose homeostasis.

Amino Acids 2012 Feb 4;42(2-3):427-40. Epub 2011 Aug 4.

Biotechnology and Molecular Medicine, A. I. Virtanen Institute for Molecular Sciences, Biocenter Kuopio, University of Eastern Finland, Kuopio Campus, P.O. Box 1627, 70211, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00726-011-1013-0DOI Listing
February 2012

The first genome-wide view of vitamin D receptor locations and their mechanistic implications.

Anticancer Res 2012 Jan;32(1):271-82

Department of Biosciences, University of Eastern Finland, P.O. Box 1627, FIN-70211 Kuopio, Finland.

View Article

Download full-text PDF

Source
January 2012

Molecular hydrogen tweezers: structure and mechanisms by neutron diffraction, NMR, and deuterium labeling studies in solid and solution.

J Am Chem Soc 2011 Dec 29;133(50):20245-57. Epub 2011 Nov 29.

WACKER-Lehrstuhl für Makromolekulare Chemie, Technische Universität München, Lichtenbergstrasse 4, D-85747 Garching bei München, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ja206394wDOI Listing
December 2011

In vitro studies on stability of L-p-boronophenylalanine-fructose complex (BPA-F).

J Radiat Res 2011 23;52(3):360-4. Epub 2011 Apr 23.

Laboratory of Organic Chemistry, Department of Chemistry, Helsinki University Central Hospital, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1269/jrr.10138DOI Listing
November 2011

Nuclear hormone 1α,25-dihydroxyvitamin D3 elicits a genome-wide shift in the locations of VDR chromatin occupancy.

Nucleic Acids Res 2011 Nov 16;39(21):9181-93. Epub 2011 Aug 16.

Department of Biosciences, University of Eastern Finland, FIN-70210 Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkr654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241659PMC
November 2011

The effect of standard chow and reduced hexokinase II on growth, cardiac and skeletal muscle hexokinase and low-flow cardiac ischaemia-reperfusion injury.

Lab Anim 2011 Jul 19;45(3):160-6. Epub 2011 Apr 19.

Laboratory of Experimental Intensive Care and Anesthesiology (LEICA), Department of Anesthesiology, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1258/la.2011.010096DOI Listing
July 2011

Enhanced chromatographic NMR with polyethyleneglycol. A novel resolving agent for diffusion ordered spectroscopy.

Magn Reson Chem 2010 Oct;48(10):777-81

Laboratory of Organic Chemistry, Department of Chemistry, University of Helsinki, A.I Virtasen aukio 1, P.O. Box 55, FIN-00014, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.2660DOI Listing
October 2010

Cerebellar glucose during fasting and acute hyperglycemia in nondiabetic men and in men with type 1 diabetes.

Cerebellum 2010 Sep;9(3):336-44

Folkhälsan Institute of Genetics, Folkhälsan Research Center, Biomedicum Helsinki, University of Helsinki, Haarmaninkatu 8, P.O. Box 63, 00014 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12311-010-0166-9DOI Listing
September 2010

Association of intramyocellular, intraperitoneal and liver fat with glucose tolerance in severely obese adolescents.

Eur J Endocrinol 2010 Sep 28;163(3):413-9. Epub 2010 Jun 28.

Hospital for Children and Adolescents, University of Helsinki, 00029 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/EJE-10-0186DOI Listing
September 2010

The down-regulation of the human MYC gene by the nuclear hormone 1alpha,25-dihydroxyvitamin D3 is associated with cycling of corepressors and histone deacetylases.

J Mol Biol 2010 Jul 21;400(3):284-94. Epub 2010 May 21.

Department of Biosciences, University of Eastern Finland, FIN-70211 Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmb.2010.05.031DOI Listing
July 2010

Evidence for abnormal glucose uptake or metabolism in thalamus during acute hyperglycaemia in type 1 diabetes--a 1H MRS study.

Metab Brain Dis 2010 Jun 28;25(2):227-34. Epub 2010 Apr 28.

Folkhälsan Institute of Genetics, Folkhälsan Research Center, Haarmaninkatu 8, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11011-010-9199-5DOI Listing
June 2010

Partial hexokinase II knockout results in acute ischemia-reperfusion damage in skeletal muscle of male, but not female, mice.

Pflugers Arch 2010 Apr 25;459(5):705-12. Epub 2010 Feb 25.

Laboratory of Experimental Intensive Care and Anesthesiology, Department of Anaesthesiology, Academic Medical Center, Meibergdreef 9, 1105 Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00424-010-0787-3
Publisher Site
http://dx.doi.org/10.1007/s00424-010-0787-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842566PMC
April 2010

Quantitative two-dimensional HSQC experiment for high magnetic field NMR spectrometers.

J Magn Reson 2010 Jan 30;202(1):24-33. Epub 2009 Sep 30.

VERIFIN, University of Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10907807090027
Publisher Site
http://dx.doi.org/10.1016/j.jmr.2009.09.021DOI Listing
January 2010

Ppargamma2 is a key driver of longevity in the mouse.

PLoS Genet 2009 Dec 4;5(12):e1000752. Epub 2009 Dec 4.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/Université Louis Pasteur, Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1000752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780700PMC
December 2009

PRESS echo time behavior of triglyceride resonances at 1.5T: detecting omega-3 fatty acids in adipose tissue in vivo.

J Magn Reson 2009 Nov 3;201(1):39-47. Epub 2009 Aug 3.

Department of Medicine, Division of Cardiology, University of Helsinki, 00029 HUS Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmr.2009.07.026DOI Listing
November 2009

General chromatographic NMR method in liquid state for synthetic chemistry: polyvinylpyrrolidone assisted DOSY experiments.

Org Lett 2009 Mar;11(6):1349-52

Laboratory of Organic Chemistry, Department of Chemistry, University of Helsinki, P.O. Box 55, FIN-00014, University of Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ol9001398DOI Listing
March 2009

Hydrophobic interactions determining functionalized lignocellulose solubility in dialkylimidazolium chlorides, as probed by 31P NMR.

Biomacromolecules 2009 Feb;10(2):458-63

Laboratory of Organic Chemistry, Department of Chemistry, Faculty of Science, University of Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bm8010159DOI Listing
February 2009

Zn pyro-pheophorbide a--fulleronicotine dyad; supramolecular self assembled donor-acceptor system for photoinduced charge separation.

Chem Commun (Camb) 2009 Feb 6(7):758-60. Epub 2009 Jan 6.

Laboratory of Organic Chemistry, Department of Chemistry, University of Helsinki, A.I Virtasen aukio 1, P.O. Box 55, FIN-00014, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/b817701eDOI Listing
February 2009

The Pro12Ala PPARgamma2 variant determines metabolism at the gene-environment interface.

Cell Metab 2009 Jan;9(1):88-98

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/Université Louis Pasteur, 67404 Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cmet.2008.11.007DOI Listing
January 2009

Risk for metabolic syndrome predisposes to alterations in the thalamic metabolism.

Metab Brain Dis 2008 Sep 22;23(3):315-24. Epub 2008 Jul 22.

Folkhälsan Institute of Genetics, Folkhälsan Research Center, Biomedicum Helsinki C330b, University of Helsinki, P.O. Box 63, 00014 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11011-008-9094-5DOI Listing
September 2008

Phosphorylation barriers to skeletal and cardiac muscle glucose uptakes in high-fat fed mice: studies in mice with a 50% reduction of hexokinase II.

Diabetes 2007 Oct 16;56(10):2476-84. Epub 2007 Jul 16.

Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/db07-0532DOI Listing
October 2007

Dissolution of wood in ionic liquids.

J Agric Food Chem 2007 Oct 2;55(22):9142-8. Epub 2007 Oct 2.

Department of Forest Biomaterials Sciences and Engineering, North Carolina State University, Raleigh, NC 27659-8005, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jf071692eDOI Listing
October 2007

PPARgamma in human and mouse physiology.

Biochim Biophys Acta 2007 Aug 27;1771(8):999-1013. Epub 2007 Mar 27.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/Université Louis Pasteur, 67404 Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbalip.2007.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2020525PMC
August 2007

Rapid and accurate processing method for amide proton exchange rate measurement in proteins.

J Biomol NMR 2007 Apr 14;37(4):313-20. Epub 2007 Feb 14.

Finnish Institute for Verification of the Chemical Weapons Convention (VERIFIN), University of Helsinki, P.O. Box 55, Helsinki 00014, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10858-007-9145-yDOI Listing
April 2007

MAGIC polymer gel for dosimetric verification in boron neutron capture therapy.

J Appl Clin Med Phys 2007 Apr 30;8(2):114-23. Epub 2007 Apr 30.

HUS, Medical Imaging Centre, Helsinki University Central Hospital, Finland.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722414PMC
http://dx.doi.org/10.1120/jacmp.v8i2.2409DOI Listing
April 2007

Histopathology in mouse metabolic investigations.

Curr Protoc Mol Biol 2007 Apr;Chapter 29:Unit 29B.4

Institut Clinique de la Souris and Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/0471142727.mb29b04s78DOI Listing
April 2007

Type I interferon response against viral and non-viral gene transfer in human tumor and primary cell lines.

J Gene Med 2007 Feb;9(2):122-35

A. I. Virtanen Institute for Molecular Sciences, Department of Biotechnology and Molecular Medicine, University of Kuopio, P.O. Box 1627, FIN-70211 Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jgm.997DOI Listing
February 2007

Noncovalent attachment of pyro-pheophorbide a to a carbon nanotube.

Chem Commun (Camb) 2007 Feb 3(5):519-21. Epub 2006 Nov 3.

Laboratory of Organic Chemistry, Department of Chemistry, University of Helsinki, A.I Virtasen aukio 1, P.O. Box 55, FIN-00014, University of Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/b611461jDOI Listing
February 2007

Evaluation of glucose homeostasis.

Curr Protoc Mol Biol 2007 Jan;Chapter 29:Unit 29B.3

A.I. Virtanen Institute for Molecular Sciences, University of Kuopio, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/0471142727.mb29b03s77DOI Listing
January 2007

Polyamine-regulated unproductive splicing and translation of spermidine/spermine N1-acetyltransferase.

RNA 2006 Aug 29;12(8):1569-82. Epub 2006 Jun 29.

Department of Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, University of Kuopio, Kuopio, finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1261/rna.39806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524884PMC
August 2006

Hexokinase II protein content is a determinant of exercise endurance capacity in the mouse.

J Physiol 2005 Jul 5;566(Pt 2):533-41. Epub 2005 May 5.

Department of Molecular Physiology ans Biophysics,Vanderbilt University School of Medicine, Nashville, TN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1113/jphysiol.2005.085043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1464755PMC
July 2005

Some aspects of quantitative 2D NMR.

J Magn Reson 2005 Jun;174(2):237-44

VERIFIN, University of Helsinki, P.O. Box 55, FIN-00014 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S109078070500023
Publisher Site
http://dx.doi.org/10.1016/j.jmr.2005.02.002DOI Listing
June 2005

Brain metabolic alterations in patients with type 1 diabetes-hyperglycemia-induced injury.

J Cereb Blood Flow Metab 2004 Dec;24(12):1393-9

Department of Endocrinology and Diabetes, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/01.WCB.0000143700.15489.B2DOI Listing
December 2004

Stimulus-induced brain lactate: effects of aging and prolonged wakefulness.

J Sleep Res 2004 Jun;13(2):111-9

Department of Physiology, Institute of Biomedicine, University of Helsinki, Biomedicum Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2869.2004.00401.xDOI Listing
June 2004

Evaluation of protein 15N relaxation times by inverse Laplace transformation.

Magn Reson Chem 2004 Jan;42(1):61-5

University of Oulu, Department of Chemistry, P.O. Box 3000, FIN-90014 Oulu, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.1309DOI Listing
January 2004

Analysis of the human hexokinase II promoter in vivo: lack of insulin response within 4.0 kb.

Biochim Biophys Acta 2004 Jan;1676(2):149-54

Department of Medicine, University of Kuopio, PO Box 1777, FIN-70211 Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbaexp.2003.11.007DOI Listing
January 2004

Hexokinase II partial knockout impairs exercise-stimulated glucose uptake in oxidative muscles of mice.

Am J Physiol Endocrinol Metab 2003 Nov 15;285(5):E958-63. Epub 2003 Jul 15.

Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232-0615, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpendo.00190.2003DOI Listing
November 2003

LR-CAHSQC: an application of a Carr-Purcell-Meiboom-Gill-type sequence to heteronuclear multiple bond correlation spectroscopy.

J Magn Reson 2003 Oct;164(2):228-32

Department of Chemistry, University of Oulu, PO Box 3000, Oulu FIN-90014, Finland.

View Article

Download full-text PDF

Source
October 2003

Quantitative 2D HSQC (Q-HSQC) via suppression of J-dependence of polarization transfer in NMR spectroscopy: application to wood lignin.

J Am Chem Soc 2003 Apr;125(14):4362-7

NMR laboratory, Structural Biology and Biophysics, Institute of Biotechnology, P.O. Box 65, FIN-00014 University of Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ja029035kDOI Listing
April 2003