Publications by authors named "Samer Hammoudeh"

22 Publications

  • Page 1 of 1

Combating COVID-19 pandemic with technology: Perceptions of Mental Health Professionals towards Telepsychiatry.

Asian J Psychiatr 2021 07 10;61:102677. Epub 2021 May 10.

Hamad Medical Corporation, Department of Psychiatry, Doha, Qatar; Qatar University, College of Medicine, Doha, Qatar.

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http://dx.doi.org/10.1016/j.ajp.2021.102677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108472PMC
July 2021

Burnout and job satisfaction among psychiatrists in the Mental Health Service, Hamad Medical Corporation, Qatar.

Asian J Psychiatr 2021 Apr 25;58:102619. Epub 2021 Feb 25.

Consultant Psychiatrist, Mental Health Service, Hamad Medical Corporation, Doha, Qatar.

Background: Job satisfaction is a critical concern among medical staff and directly affects patient safety and quality of health care services. Burnout has been reported to be correlated with job satisfaction.

Aims: This study aimed to determine the prevalence of burnout and level of job satisfaction among psychiatrists working in the Mental Health Service, Hamad Medical Corporation, Qatar, and examine correlations among socio-demographic variables, burnout, and job satisfaction.

Method: A cross-sectional survey was conducted using a socio-demographic questionnaire, the Maslach Burnout Inventory (MBI), and the Job Descriptive Index (JDI).

Results: One-third of psychiatrists reported high levels of emotional exhaustion, with a similar proportion describing low levels of personal accomplishment. Less than 20 % demonstrated high levels of depersonalization. Trainees were more burned out than senior psychiatrists. Opportunities for promotion was the only factor with which the majority of psychiatrists were not satisfied.

Conclusions: The prevalence of high burnout in psychiatrists remains lower in Qatar than in other countries. Lower levels of satisfaction with co-workers, work, supervision, opportunities for promotion, and the job in general increased emotional exhaustion and depersonalization. Interestingly, satisfaction with salary did not have a significant effect on burnout.
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http://dx.doi.org/10.1016/j.ajp.2021.102619DOI Listing
April 2021

Metabolic syndrome among adults in Qatar: A review of the literature across medical specialties.

Qatar Med J 2020 3;2020(3):43. Epub 2021 Feb 3.

Medical Research Center, Research Affairs, Hamad Medical Corporation, Doha, Qatar E-mail:

This study aims to collate all metabolic syndrome-related studies among adults in Qatar, shedding light on gaps in knowledge related to this topic to be addressed in future research studies. PubMed was used in searching for metabolic syndrome-related articles in Qatar, which was executed using relevant terms and was conducted with no restrictions. A second search was executed at a later stage to include any recent publications. A total of 20 articles were found to be relevant and related to the topic in hand. Three definitions of metabolic syndrome were used across the reviewed studies, which were classified based on medical specialties. The main findings and key components of each study were summarized. Studies were unevenly distributed across various medical specialties. This article serves to direct future research activities by identifying what aspects of the disease have been covered under current or past research projects and what more needs to be addressed comprehensively in view of clinical and public health significance.
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http://dx.doi.org/10.5339/qmj.2020.43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856911PMC
February 2021

Patterns of prescription of antipsychotics in Qatar.

PLoS One 2020 9;15(11):e0241986. Epub 2020 Nov 9.

Psychiatry Department, Weill Cornell Medical College, Doha, Qatar.

Objective: Even though all guidelines recommend generally against antipsychotic polypharmacy, antipsychotic polypharmacy appears to be a very common practice across the globe. This study aimed to examine the prescription patterns of antipsychotics in Qatar, in comparison with the international guidelines, and to scrutinize the sociodemographic and clinical features associated with antipsychotic polypharmacy.

Methods: All the medical records of all the inpatients and outpatients treated by antipsychotics at the Department of Psychiatry-Hamad Medical Corporation (HMC) in Doha, Qatar (between October 2012 and April 2014) were retrospectively analyzed. We retrieved the available sociodemographic data, psychiatric features, and details on the medication history.

Results: Our sample consisted of 537 individuals on antipsychotics (2/3 were male; mean age 33.8±10.2 years), prescribed for a psychotic disorder in 57%, a mood disorder in 9.3%, and various other diagnoses in 33.7%. About 55.9% received one antipsychotic, 29.6% received two antipsychotics, and 14.5% received more than two antipsychotics. Polypharmacy was associated with younger age (p = 0.025), being single (p<0.001), the diagnosis of a psychotic disorder (p<0.001), and previous admissions to psychiatry (p<0.001).

Conclusions: Antipsychotic polypharmacy appears to be quite common in Qatar, as it is the case in many other countries, in contrast with most international recommendations. Studies are needed to explore the reasons behind this disparity.
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0241986PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652328PMC
January 2021

Correction to: Self-Reported Sleep and Exercise Patterns in Patients with Schizophrenia: A Cross-Sectional Comparative Study.

Int J Behav Med 2020 Apr;27(2):255

Department of Psychiatry, Weill Cornell Medicine-Qatar, Education City, P.O. Box 24144, Doha, Qatar.

The article Self-Reported Sleep and Exercise Patterns in Patients with Schizophrenia: a Cross-Sectional Comparative Study written by Nancy Kiwan, Ziyad Mahfoud, Suhaila Ghuloum, Rifka Chamali, Arij Yehya, Samer Hammoudeh, Yahya Hani, Iman Amro, and Hassen Al-Amin.
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http://dx.doi.org/10.1007/s12529-020-09851-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109174PMC
April 2020

Risk Factors of Metabolic Syndrome Among Patients Receiving Antipsychotics: A Retrospective Study.

Community Ment Health J 2020 05 28;56(4):760-770. Epub 2019 Dec 28.

Psychiatry Department, Weill Cornell Medicine - Qatar, Education city, P.O. Box: 24144, Doha, Qatar.

This study aimed to assess the differential effects of first-generation (FGA) and second-generation antipsychotics (SGA) on the prevalence of risk factors for metabolic syndrome among mentally ill patients in Qatar. We also wanted to check if there is proper adherence with the guidelines for prescribing antipsychotics and the monitoring of metabolic effects in this population. We collected the available retrospective data (socio-demographic, psychiatric, anthropometric, and metabolic measures) from the records of 439 patients maintained on antipsychotics. The majority were males, married, employed, having a psychotic disorder, and receiving SGA. Patients on SGA showed more obesity, higher BP, and more elevated triglycerides compared to those on FGA. The prevalence of the abnormal metabolic measures was high in this sample, but those on SGA showed a significantly higher prevalence of abnormal body mass index and BP. Obesity and hypertension were common in patients maintained on antipsychotics, especially those on SGA. Polypharmacy was common, and many metabolic measures were not monitored properly in those maintained on antipsychotics. More prospective studies with guided monitoring of the patients' clinical status and metabolic changes are needed to serve better this population of patients.
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http://dx.doi.org/10.1007/s10597-019-00537-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089884PMC
May 2020

Self-Reported Sleep and Exercise Patterns in Patients with Schizophrenia: a Cross-Sectional Comparative Study.

Int J Behav Med 2020 Aug;27(4):366-377

Department of Psychiatry, Weill Cornell Medicine-Qatar, Education City, P.O. Box 24144, Doha, Qatar.

Background: Adequate sleep and physical activity have been linked to the overall well-being of both medical and psychiatric patients. Patients with schizophrenia have shown abnormal sleep patterns and decreased physical activity that were linked to their psychopathology and physical health. These phenomena are not studied yet in Arab patients with schizophrenia. The purpose of this study is to study the sleep and exercise patterns in Arab patients with schizophrenia compared with those of healthy controls.

Method: A total of 99 patients with schizophrenia and 101 controls were recruited. Arabic versions of sleep, exercise, socio-demographic, and clinical questionnaires were administered as well as the validated scales to measure psychopathology, depression, and suicidality in these participants.

Results: The majority of patients with schizophrenia slept more than 8 h per day and exercised less when compared with controls. Sleep quality was worse in those with higher depression score and higher suicidality scores were seen in patients with lower sleep duration. Multinomial regression showed that patients with schizophrenia have higher odds of sleeping more than 8 h even after controlling for the intake of antipsychotics, age, gender, smoking status, and other confounding factors.

Conclusion: Our results showed that Arab patients with schizophrenia are at increased risk of having longer sleep duration with inadequate physical activity, which are correlating with worsening of depressive symptoms and suicidality. Thus, more attention should be paid to the changes in sleep patterns and level of exercise when treating Arab patients with schizophrenia.
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http://dx.doi.org/10.1007/s12529-019-09830-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359133PMC
August 2020

Approaching two decades of cystic fibrosis research in Qatar: a historical perspective and future directions.

Multidiscip Respir Med 2019 1;14:29. Epub 2019 Oct 1.

Pediatric Pulmonology, Pediatric Medicine, Sidra Medicine, PO Box 26999, Doha, Qatar.

Cystic fibrosis (CF) is a genetic disease caused by a defect of CF transmembrane conductance regulator (CFTR) gene. CF affects multiple systems, predominantly with respiratory involvement. In Qatar, researchers have been exploring various aspects of the disease for almost 20 years. PubMed and Google Scholar were reviewed for articles related to CF in Qatar. The first publication appeared in the year 2000. Since then, several studies have been conducted on CF patients in Qatar considering a variety of topics. The presence of the CFTR I1234V mutation in a certain Arab tribe stands out as a distinguishing characteristic of CF patients in Qatar when compared to the larger Arab region or even worldwide. We aim here to summarize the existing CF research conducted in Qatar over the years as well as to introduce topics for future research.
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http://dx.doi.org/10.1186/s40248-019-0193-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771098PMC
October 2019

Relationships between sleep patterns and metabolic profile in patients maintained on antipsychotics: a cross-sectional comparative study.

Neuropsychiatr Dis Treat 2019 19;15:2035-2047. Epub 2019 Jul 19.

Department of Psychiatry, Weill Cornell Medicine - Qatar, Doha, Qatar.

Background: Disturbances in sleep duration and quality have been associated with obesity and other metabolic changes. Patients with mental disorders (MD) are known to have more sleep problems, and antipsychotics (AP), used in the treatment of these patients, can also cause weight gain. This study aimed to compare the self-reported sleep patterns between psychiatric patients (on or off AP) and controls. We also evaluated the associations between the clinical and metabolic profiles with short or long sleep duration.

Methods: A total of 339 subjects was recruited: Mentally ill patients maintained on AP for at least six months (MD+AP, n=112), patients not taking AP for at least the last six months before enrollment (MD/noAP, n=101), and non-psychiatry controls (HC, n=126). Multinomial regression analysis was applied to find the predictors of irregular sleep duration in this sample.

Results: More mentally ill patients (MD+AP and MD/noAP) reported a sleep duration of >8 hrs than HC. Patients from MD/noAP showed more insomnia than HC. Sleep disturbances were significantly more frequent in MD+AP than HC. Participants who reported sleeping >8 hrs had higher body mass index and waist circumference than those who slept <7 hrs.

Conclusion: Female gender, central obesity and being mentally ill were independently associated with long sleep duration (>8h) in the population of Qatar.
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http://dx.doi.org/10.2147/NDT.S207987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650465PMC
July 2019

Cross-cultural adaptation of the Arabic Positive and Negative Syndrome Scale in schizophrenia: Qualitative analysis of a focus group.

Transcult Psychiatry 2019 10 27;56(5):973-991. Epub 2019 May 27.

Weill Cornell Medicine - Qatar.

As part of a project to translate and validate scales used in the diagnosis and treatment of Arab patients with schizophrenia, this study aimed to explore the experience of clinical research coordinators (CRCs) while administering the Arabic version of the Positive and Negative Syndrome Scale (PANSS) on Arab schizophrenia patients. We previously reported that the Arabic version of PANSS is a valid and reliable tool to assess Arab patients with schizophrenia. Five CRCs and the principal investigator attended focus group discussions on cultural issues in administering the PANSS. A thematic analysis approach was utilized for data coding and analysis. The results identified issues related to the translation of the instrument, the structure of the interview, the cultural sensitivity of some questions, and the procedures for rating items of the PANSS. Qualitative analysis also identified four main themes relevant to clinical assessment of patients from Middle Eastern cultures: religion, beliefs and values, gender, and semantic expressions. In conclusion, researchers or clinicians administering the PANSS scale interview in Arabic should be trained to consider the roles of local dialects, familiarity with abstract thinking, religion, and social constructs when assessing psychosis.
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http://dx.doi.org/10.1177/1363461519850345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745612PMC
October 2019

Asthma and obesity in the Middle East region: An overview.

Ann Thorac Med 2019 Apr-Jun;14(2):116-121

Medical Research Center, Research Affairs, Hamad Medical Corporation, Doha, Qatar.

This paper aims to cover the current status of asthma and obesity in the Middle East, as well as to introduce the various studies tying the two diseases; further expanding on the proposed mechanisms. Finally, the paper covers recent literature related to sphingolipids and its role in asthma, followed by recommendations and future directions. In preparation of this paper, we searched PubMed and Google Scholar, with no restrictions, using the following terms; asthma, obesity, Middle East, sphingolipids. We also used the reference list of retrieved articles to further expand on the pool of articles that were used for this review.
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http://dx.doi.org/10.4103/atm.ATM_115_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467016PMC
April 2019

Primary ciliary dyskinesia among Arabs: Where do we go from here?

Paediatr Respir Rev 2019 Feb 15;29:19-22. Epub 2018 Sep 15.

Medical Research Center, Research Affairs, Hamad Medical Corporation, PO Box 3050, Doha, Qatar; Pediatric Pulmonology, Sidra Medicine, PO Box 2699, Doha, Qatar. Electronic address:

Primary ciliary dyskinesia (PCD), also known as immotile-cilia syndrome, is a rare genetic disease that is inherited in an autosomal recessive manner. Several studies have explored certain aspects of PCD in the Arab world, yet much is still lacking in terms of identifying the different characteristics of this disease. In this paper, we aim to briefly cover those studies published about PCD in Arab countries, as well as to provide recommendations and guidelines for future studies.
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http://dx.doi.org/10.1016/j.prrv.2018.09.002DOI Listing
February 2019

Rheumatic manifestations of inflammatory bowel diseases: A study from the Middle East.

J Int Med Res 2018 Sep 2;46(9):3837-3847. Epub 2018 Jul 2.

4 Research Department, Weill Cornell Medicine-Qatar, Doha, Qatar.

Objective To examine the prevalence of rheumatic manifestations among patients with inflammatory bowel disease (IBD). Methods This prospective study enrolled patients with IBD in whom the diagnosis and extent of IBD were confirmed by colonoscopy and histopathology. Patients were interviewed and examined by a rheumatologist. A complete rheumatological examination, X-rays of the lumbosacral and sacroiliac joints and HLA-B27 blood tests were performed. Results A total of 127 adult patients were recruited: 46 (36.2%) with Crohn's disease (CD) and 81 (63.8%) with ulcerative colitis (UC). Rheumatic manifestations of any type were present in 57.5% (73 of 127 patients) with no significant differences between CD and UC. Peripheral manifestations were present in 43.3% (55 of 127 patients), four patients (3.1%) had axial arthritis alone and 14 patients (11.0%) had both types. Among those with peripheral manifestations, five patients (7.2%) had type 1 arthritis (pauciarticular) and one patient (1.4%) had type 2 arthritis (polyarticular). A higher proportion of patients with CD had axial manifestations with or without peripheral manifestations (eight of 46; 17.4%) compared with patients with UC (10 of 81; 12.3%), but no difference was observed in patients with peripheral manifestations alone. Conclusions Rheumatic manifestations in patients with IBD in Qatar are more prevalent than in other regions of the world. Peripheral manifestations were more prevalent than axial.
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http://dx.doi.org/10.1177/0300060518781404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136032PMC
September 2018

Oral Manifestations of Systemic Lupus Erythematosus Patients in Qatar: A Pilot Study.

Int J Rheumatol 2018 10;2018:6052326. Epub 2018 Apr 10.

Research Department, Weill Cornell Medicine-Qatar, P.O. Box 24144, Doha, Qatar.

Objective: The purpose of this pilot study was to assess the prevalence of oral manifestations among systemic lupus erythematosus (SLE) patients in Qatar, in order to warrant future studies that would investigate each one of these manifestations with detail and further scrutiny.

Methods: Study procedures took place between November 2014 and April 2016. All patients visiting the outpatient rheumatology clinics at Hamad General Hospital, Doha, Qatar, were asked to join. The American College of Rheumatology (ACR) 1997 criteria of SLE were used. The patients were examined initially by a rheumatologist and were later scheduled for an appointment with a dentist at the same institution. A total of 77 patients were recruited for the study.

Results: Prevalence rates for the different oral manifestations ranged from 2.4% for soft palate ulcers, cheilitis, and oral candida to 88.1% for the presence of cavitation. Gingivitis, periodontal disease, cavities, and missing teeth were observed in more than 50% of the sample. The prevalence of periodontal disease and missing teeth was higher among those with an SLE duration > 8 years. On the contrary, the prevalence of gingivitis and cavities was higher among those with an SLE duration ≤ 8 years.

Conclusion: This study found high rates of gingivitis, periodontal disease, cavities, and missing teeth among SLE patients in Qatar. It is recommended that healthcare providers of such patients monitor the presence of any oral manifestations in order to arrange for early treatment and prevention efforts. Future prospective longitudinal studies with adequate sample size and power are needed in order to ascertain any causation factors or common etiology pathways.
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http://dx.doi.org/10.1155/2018/6052326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914093PMC
April 2018

The prevalence of metabolic syndrome in patients receiving antipsychotics in Qatar: a cross sectional comparative study.

BMC Psychiatry 2018 03 27;18(1):81. Epub 2018 Mar 27.

Department of Psychiatry, Weill Cornell Medicine - Qatar, Education city, P.O. Box 24144, Doha, Qatar.

Background: Metabolic abnormalities are common in patients maintained on antipsychotics. These abnormalities increase the risk of cardiovascular diseases and mortality in this population. The aim of this study is to assess the prevalence of metabolic syndrome (MetS) in subjects maintained on antipsychotics relative to controls in Qatar, and to assess the factors contributing to the development of MetS.

Methods: A cross sectional design was used to collect data and fasting blood samples from subjects maintained on antipsychotics for at least six months (n = 112) and from a control group (n = 114). The groups were compared in regard to prevalence of MetS, and multiple regression analysis was used to determine the risk factors in each group.

Results: The two groups (antipsychotics vs. control) were similar in regard to age (35.73 ± 10.28 vs. 35.73 ± 8.16 years) and gender ratio. The MetS was higher among the subjects on antipsychotics, but this difference did not reach statistical significance. Blood pressure (BP) was significantly higher in the antipsychotics group and BMI was the major risk factor to develop MetS in this group.

Conclusions: The prevalence of MetS in both groups is high and mostly attributed to obesity and high BP. Public health interventions are needed to address this major health problem overall. Larger studies are needed to further assess the impact of antipsychotics and mental illness on the development of MetS.
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http://dx.doi.org/10.1186/s12888-018-1662-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870932PMC
March 2018

Validation of the Five-Factor Model of the Arabic Version of the Positive and Negative Syndrome Scale in Schizophrenia.

Psychopathology 2017 18;50(3):211-218. Epub 2017 May 18.

Department of Research, Weill Cornell Medicine - Qatar, Doha, Qatar.

Background: The Positive and Negative Syndrome Scale (PANSS) is a widely used assessment for patients with schizophrenia across clinical and research settings. This scale allows the classification of the psychotic symptoms to better understand the psychopathology in patients with schizophrenia. There are no available data on the different components of psychopathology in Arab patients with schizophrenia.

Objectives: This study examined the factor structure of the validated Arabic version of the PANSS in a sample of Arab patients with schizophrenia.

Methods: The Arabic version of the PANSS was administered to 101 patients with schizophrenia, and principal component analysis (PCA) was carried out after the cross-cultural adaptation and validation of this version.

Results: This sample had more males (66.3%) than females (33.7%) with a mean age of 35.03 years (SD = 9.99). PCA showed that 28 items loaded on 5 components: cognitive, negative, excited, depressed and positive. These factors explained 63.19% of variance. The 2 remaining items, grandiosity and somatic concerns, did not load well on any of these components.

Conclusion: Our results support the common 5-dimension PANSS model shown in other cultures with different languages. Nevertheless, there were minor differences, which could reflect cultural or semantic differences.
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http://dx.doi.org/10.1159/000472154DOI Listing
January 2018

Advanced glycation end products among patients maintained on antipsychotics.

Int Clin Psychopharmacol 2017 09;32(5):256-261

Departments of aResearch bHealth Policy and Research cPhysiology and Biophysics dPsychiatry, Weill Cornell Medicine - Qatar eDepartment of Psychiatry, Rumailah Hospital, Hamad Medical Corporation fPrimary Healthcare Corporation, Doha, Qatar.

The aim of this study was to measure advanced glycation end products (AGEs) among participants maintained on antipsychotics using the AGE Reader and to compare them with controls from the general population. Participants maintained on antipsychotics for at least 6 months were recruited from the Psychiatry Department at Rumailah Hospital, Doha, Qatar. Healthy controls were recruited from the primary healthcare centers in Doha, Qatar. AGEs of a total of 86 participants (48 patients and 38 controls) were recorded. Among the group maintained on antipsychotics, women, smokers, and Arabs had significantly higher AGEs levels compared with men, nonsmokers, and non-Arabs, respectively (P<0.05). The levels of AGEs were higher among the group of patients maintained on antipsychotics in comparison to controls; however, the difference did not reach statistical significance. This is the first study to examine AGEs in patients maintained on antipsychotics. Our findings showed that such patients do not differ significantly from controls comparing AGEs levels. Future investigations might need to consider recruiting a larger sample size using a prospective design.
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http://dx.doi.org/10.1097/YIC.0000000000000179DOI Listing
September 2017

Advanced glycation end products among patients maintained on antipsychotics.

Int Clin Psychopharmacol 2017 09;32(5):256-261

Departments of aResearch bHealth Policy and Research cPhysiology and Biophysics dPsychiatry, Weill Cornell Medicine - Qatar eDepartment of Psychiatry, Rumailah Hospital, Hamad Medical Corporation fPrimary Healthcare Corporation, Doha, Qatar.

The aim of this study was to measure advanced glycation end products (AGEs) among participants maintained on antipsychotics using the AGE Reader and to compare them with controls from the general population. Participants maintained on antipsychotics for at least 6 months were recruited from the Psychiatry Department at Rumailah Hospital, Doha, Qatar. Healthy controls were recruited from the primary healthcare centers in Doha, Qatar. AGEs of a total of 86 participants (48 patients and 38 controls) were recorded. Among the group maintained on antipsychotics, women, smokers, and Arabs had significantly higher AGEs levels compared with men, nonsmokers, and non-Arabs, respectively (P<0.05). The levels of AGEs were higher among the group of patients maintained on antipsychotics in comparison to controls; however, the difference did not reach statistical significance. This is the first study to examine AGEs in patients maintained on antipsychotics. Our findings showed that such patients do not differ significantly from controls comparing AGEs levels. Future investigations might need to consider recruiting a larger sample size using a prospective design.
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http://dx.doi.org/10.1097/YIC.0000000000000179DOI Listing
September 2017

Validation of the Arabic Version of Calgary Depression Scale for Schizophrenia.

PLoS One 2016 1;11(9):e0162304. Epub 2016 Sep 1.

Department of Psychiatry, Weill Cornell Medicine - Qatar, Doha, Qatar.

Background: Patients with schizophrenia commonly show both depressive and negative symptoms that can differentially affect the prognosis and course of treatment. The Calgary Depression Scale for Schizophrenia (CDSS) was designed to distinguish between depression and negative symptoms in patients with schizophrenia. The purpose of this study is to validate an Arabic version of the CDSS among patients with schizophrenia.

Methods: The diagnosis of schizophrenia was confirmed using the Arabic Mini International Neuropsychiatric Interview 6 (MINI 6). A standardized translation back-translation process was adopted. One rater administered the Arabic CDSS to subjects with schizophrenia as well as to a control group who should not have any psychiatric disorder except for depression. Another rater, blinded to the results administered the already validated Arabic version of Beck Depression Inventory-II (BDI-II).

Results: We recruited 102 patients and 102 controls subjects. The CDSS showed good internal consistency in the active group (Cronbach's alpha = 0.82). The Intraclass Coefficient correlations (ICC) for the inter-rater reliability (n = 21) was 0.90, p<0.05 and test-retest reliability (n = 19) was 0.85, p<0.001. When compared to the BDI-II, the cutoff score of 5 on the Arabic CDSS showed reasonable sensitivity and specificity of 72.75% and 67.95% respectively.

Conclusions: The psychometric properties of the Arabic version of CDSS demonstrate that it is a valid tool to assess the depressive symptoms in the Arab patients with schizophrenia.
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0162304PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008865PMC
August 2017

Validity and Reliability of the Arabic Version of the Positive and Negative Syndrome Scale.

Psychopathology 2016;49(3):181-7. Epub 2016 Jul 30.

Department of Research, Weill Cornell Medicine-Qatar, Doha, Qatar.

Background: The Positive and Negative Syndrome Scale (PANSS) is widely used for patients with schizophrenia. This scale is reliable and valid. The PANSS was translated and validated in several languages.

Objective: The aim of this study was to translate and validate the PANSS in the Arab population.

Subjects And Methods: The PANSS was translated into formal Arabic language using the back-translation method. 101 Arab patients with schizophrenia and 98 Arabs with no diagnosis of any mental disorder were recruited. The Arabic version of the Mini International Neuropsychiatric Interview (MINI-6) was used as a diagnostic tool to confirm the diagnosis of schizophrenia or rule out any diagnosis for the healthy control group. Reliability of the scale was assessed by calculating internal consistency, interrater reliability and test-retest reliability. Construct validity was assessed using the Arabic version of the MINI-6. PANSS total scores were correlated with the Clinical Global Impression-Severity scale.

Results: Our findings showed that the internal consistency was good (0.92). Scores on the PANSS of the patients were much higher than those of the healthy controls. The PANSS showed good interrater reliability and test-retest reliability (0.92 and 0.75, respectively). In comparison with the MINI-6, the PANSS showed good sensitivity and specificity, which implies good construct validity of this version.

Conclusion: In conclusion, the Arabic version of the PANSS is a reliable and valid instrument for the assessment of patients with schizophrenia in the Arab population.
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http://dx.doi.org/10.1159/000447328DOI Listing
December 2016

An assessment of patients' knowledge of osteoporosis in Qatar: A pilot study.

Qatar Med J 2015 31;2015(2):13. Epub 2015 Dec 31.

Department of Medicine, Rheumatology Section, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.

Osteoporosis is a disease that affects the bones. It leads to increased risk of fractures as a result of decreased bone mineral density. The goal of this study was to assess the general perception of osteoporosis as well as knowledge of lifestyle, risk factors, and preventive measures among patients in Qatar. The study was conducted between September 2013 and September 2014. The study subjects (n = 93) were patients diagnosed with osteoporosis who attended the Outpatient Rheumatology Clinic at Hamad General Hospital in Doha, Qatar. The results showed that those with a university or graduate degree had a significantly higher level of knowledge about osteoporosis (p = 0.009) than those with less education. Among those in our study, knowledge related to osteoporosis was principally obtained through media sources such as television and radio (39%). In conclusion, osteoporosis patients in Qatar need a better understanding of the disease. Identifying thought patterns related to the perception of osteoporosis and treatment might assist in building a foundation for management modalities and effective preventive strategies for the disease in Qatar.
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http://dx.doi.org/10.5339/qmj.2015.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719434PMC
February 2016

The effect of non-exercise activity thermogenesis on subjects with metabolic syndrome - a proof of concept study in Qatar.

Qatar Med J 2013 1;2013(1):12-8. Epub 2013 Nov 1.

PO Box 5751, Doha, Qatar.

Metabolic syndrome is a cluster of metabolic abnormalities that increases the risk of cardiovascular disease and type 2 diabetes. Total human energy expenditure is divided into three major components; resting metabolic rate, thermic effect of food, and activity thermogenesis which is divided into exercise and non exercise activity thermogenesis (NEAT). In this study, NEAT was used as a lifestyle intervention on subjects with metabolic syndrome. 200 eligible patients from the Diabetes and Endocrinology Department at Hamad Medical Hospital in Doha, Qatar were assigned to an intervention (n = 100) or control (n = 100) group and followed for one year. The intervention group was advised to practice NEAT enhancing activities, while the control group was not advised about NEAT. Measurements of waist circumference, weight, BMI, blood pressure, glucose and lipid profile were assessed at baseline, six months and 1 year. After 1 year 52 intervention and 55 control subjects completed the study. The results revealed no statistically significant differences in metabolic syndrome components between the two randomized groups. The amount of recommended NEAT activity appears to have been too small to influence study outcomes. Future studies in similar populations may need to consider the high dropout rate, and use of incentives or other interventions to increase compliance and retention.
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http://dx.doi.org/10.5339/qmj.2013.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991052PMC
July 2014