Samantha Miller

Samantha Miller

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Samantha Miller

Samantha Miller

Publications by authors named "Samantha Miller"

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Interaction of the Mechanosensitive Channel, MscS, with the Membrane Bilayer through Lipid Intercalation into Grooves and Pockets.

J Mol Biol 2019 Aug 4;431(17):3339-3352. Epub 2019 Jun 4.

School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2019.05.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787928PMC
August 2019

Reducing Acute Kidney Injury and Costs of Percutaneous Coronary Intervention by Patient-Centered, Evidence-Based Contrast Use.

Circ Cardiovasc Qual Outcomes 2019 03;12(3):e004961

Cardiovascular Division (A.P.A., M.F., H.I.K., J.M.L., A.Z., R.G.B., N.F., S.J., J.S.), Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.1161/CIRCOUTCOMES.118.004961DOI Listing
March 2019

Novel bacterial lineages associated with boreal moss species.

Environ Microbiol 2018 07 22;20(7):2625-2638. Epub 2018 Aug 22.

Cooperative Institute for Research in Environmental Sciences, University of Colorado at Boulder, Boulder, CO, USA.

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http://dx.doi.org/10.1111/1462-2920.14288DOI Listing
July 2018

Targeting the Breast Cancer Kinome.

J Cell Physiol 2017 01 31;232(1):53-60. Epub 2016 May 31.

Department of Pharmacology, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1002/jcp.25427DOI Listing
January 2017

On the mobility, membrane location and functionality of mechanosensitive channels in Escherichia coli.

Sci Rep 2016 09 6;6:32709. Epub 2016 Sep 6.

Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology &Zernike Institute for Advanced Materials, University of Groningen, 9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1038/srep32709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011748PMC
September 2016

Weight loss reduces basal-like breast cancer through kinome reprogramming.

Cancer Cell Int 2016 1;16:26. Epub 2016 Apr 1.

CB 7461, Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, 2203 McGavran Greenberg Hall, Chapel Hill, NC 27599-7461 USA ; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC USA.

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http://dx.doi.org/10.1186/s12935-016-0300-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818517PMC
April 2016

The photochemical thiol-ene reaction as a versatile method for the synthesis of glutathione -conjugates targeting the bacterial potassium efflux system Kef.

Org Chem Front 2016 Apr 26;3(4):439-446. Epub 2016 Feb 26.

Department of Chemistry , Chemistry Research Laboratory , University of Oxford , Mansfield Road , Oxford , OX1 3TA , UK . Email: ; Email:

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http://dx.doi.org/10.1039/c5qo00436eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819703PMC
April 2016

Epigenetic inhibition of adaptive bypass responses to lapatinib by targeting BET Bromodomains.

Mol Cell Oncol 2016 Jan 10;3(1):e1052182. Epub 2015 Jun 10.

Department of Pharmacology, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine , Chapel Hill, NC, USA.

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http://dx.doi.org/10.1080/23723556.2015.1052182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845204PMC
January 2016

Properties of the Mechanosensitive Channel MscS Pore Revealed by Tryptophan Scanning Mutagenesis.

Biochemistry 2015 Jul 20;54(29):4519-30. Epub 2015 Jul 20.

†School of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, United Kingdom.

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http://dx.doi.org/10.1021/acs.biochem.5b00294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519979PMC
July 2015

The evolution of bacterial mechanosensitive channels.

Cell Calcium 2015 Mar 25;57(3):140-50. Epub 2014 Dec 25.

Institute of Biological and Environmental Sciences, Cruikshank Building, University of Aberdeen, St Machar Drive, Aberdeen AB24 3UU, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ceca.2014.12.011DOI Listing
March 2015

Interleukin-1α released from HSV-1-infected keratinocytes acts as a functional alarmin in the skin.

Nat Commun 2014 Oct 17;5:5230. Epub 2014 Oct 17.

Department of Microbiology and Immunology, Temple Autoimmunity Center, Temple University School of Medicine, 1158 MERB, 3500 N Broad Street, Philadelphia, Pennsylvania 19140, USA.

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http://dx.doi.org/10.1038/ncomms6230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237007PMC
October 2014

Understanding the structural requirements for activators of the Kef bacterial potassium efflux system.

Biochemistry 2014 Apr 21;53(12):1982-92. Epub 2014 Mar 21.

Department of Chemistry, Chemistry Research Laboratory, University of Oxford , Mansfield Road, Oxford OX1 3TA, United Kingdom.

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http://dx.doi.org/10.1021/bi5001118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004266PMC
April 2014

Mechanosensitive channels and bacterial cell wall integrity: does life end with a bang or a whimper?

J R Soc Interface 2014 Feb 20;11(91):20130850. Epub 2013 Nov 20.

School of Chemistry and COSMIC, University of Edinburgh, , The King's Buildings, Edinburgh EH9 3JJ, UK.

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http://dx.doi.org/10.1098/rsif.2013.0850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869158PMC
February 2014

Probing the structure of the mechanosensitive channel of small conductance in lipid bilayers with pulsed electron-electron double resonance.

Biophys J 2014 Feb;106(4):834-42

Institute of Physical and Theoretical Chemistry, University of Bonn, Bonn, Germany; Centre for Biomolecular Sciences, University of St. Andrews, St. Andrews, Scotland. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2014.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944623PMC
February 2014

Characterization of three novel mechanosensitive channel activities in Escherichia coli.

Channels (Austin) 2012 Jul-Aug;6(4):272-81. Epub 2012 Jul 1.

School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Aberdeen, Scotland, UK.

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http://dx.doi.org/10.4161/chan.20998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508906PMC
April 2013

Optimality in DNA repair.

J Theor Biol 2012 Jan 19;292:39-43. Epub 2011 Sep 19.

Institute of Complex Systems and Mathematical Biology, King's College, University of Aberdeen, Aberdeen, UK.

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http://dx.doi.org/10.1016/j.jtbi.2011.08.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071444PMC
January 2012

KefF, the regulatory subunit of the potassium efflux system KefC, shows quinone oxidoreductase activity.

J Bacteriol 2011 Sep 8;193(18):4925-32. Epub 2011 Jul 8.

School of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, United Kingdom.

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http://dx.doi.org/10.1128/JB.05272-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165647PMC
September 2011

Sensing bilayer tension: bacterial mechanosensitive channels and their gating mechanisms.

Biochem Soc Trans 2011 Jun;39(3):733-40

Department of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, U.K.

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http://dx.doi.org/10.1042/BST0390733DOI Listing
June 2011

A matter of life or death: modeling DNA damage and repair in bacteria.

Biophys J 2011 Feb;100(4):814-21

Institute of Complex Systems and Mathematical Biology, SUPA, King's College, University of Aberdeen, Aberdeen, United Kingdom.

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http://dx.doi.org/10.1016/j.bpj.2010.12.3713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037714PMC
February 2011

Collective response of self-organized clusters of mechanosensitive channels.

Phys Rev E Stat Nonlin Soft Matter Phys 2011 Feb 4;83(2 Pt 1):020901. Epub 2011 Feb 4.

Institute for Complex Systems and Mathematical Biology, King's College, University of Aberdeen, Aberdeen AB243UE, United Kingdom.

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http://dx.doi.org/10.1103/PhysRevE.83.020901DOI Listing
February 2011

The critical role of S-lactoylglutathione formation during methylglyoxal detoxification in Escherichia coli.

Mol Microbiol 2010 Dec 29;78(6):1577-90. Epub 2010 Oct 29.

School of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK.

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http://dx.doi.org/10.1111/j.1365-2958.2010.07426.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412212PMC
December 2010

Mechanism of ligand-gated potassium efflux in bacterial pathogens.

Proc Natl Acad Sci U S A 2010 Nov 1;107(46):19784-9. Epub 2010 Nov 1.

Drug Development Department, Nevada Cancer Institute, Las Vegas, NV 89135, USA.

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http://dx.doi.org/10.1073/pnas.1012716107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993342PMC
November 2010

Tryptophan in the pore of the mechanosensitive channel MscS: assessment of pore conformations by fluorescence spectroscopy.

J Biol Chem 2010 Feb 26;285(8):5377-84. Epub 2009 Dec 26.

School of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, Scotland, United Kingdom.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M109.071472
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http://dx.doi.org/10.1074/jbc.M109.071472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820766PMC
February 2010

Evaluation of synergistic antioxidant potential of complex mixtures using oxygen radical absorbance capacity (ORAC) and electron paramagnetic resonance (EPR).

J Agric Food Chem 2010 Jan;58(1):209-17

Department of Nutrition, Dietetics, and Food Science, Brigham Young University, S-135 ESC, Provo, Utah 84602, USA.

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http://dx.doi.org/10.1021/jf903080fDOI Listing
January 2010

A gene expression classifier of node-positive colorectal cancer.

Neoplasia 2009 Oct;11(10):1074-83

Department of Pathology, Microbiology and Immunology, University of South Carolina, Columbia, SC 29208, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745673PMC
http://dx.doi.org/10.1593/neo.09808DOI Listing
October 2009

Habitual response to stress in recovering adolescent anorexic patients.

Child Psychiatry Hum Dev 2009 Mar 11;40(1):43-54. Epub 2008 Jul 11.

Department of Psychiatry and Behavioral Sciences, Stanford University, 401 Quarry Road, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1007/s10578-008-0112-yDOI Listing
March 2009

Acute effects of acamprosate and MPEP on ethanol Drinking-in-the-Dark in male C57BL/6J mice.

Alcohol Clin Exp Res 2008 Nov 6;32(11):1992-8. Epub 2008 Sep 6.

Department of Psychology, The Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

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http://dx.doi.org/10.1111/j.1530-0277.2008.00787.xDOI Listing
November 2008

Personality correlates of physiological response to stress among incarcerated juveniles.

Z Kinder Jugendpsychiatr Psychother 2008 May;36(3):185-90

University of California, San Francisco,CA 94143-0850, USA.

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http://dx.doi.org/10.1024/1422-4917.36.3.185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104598PMC
May 2008

Physiological analysis of bacterial mechanosensitive channels.

Methods Enzymol 2007 ;428:47-61

School of Medical Sciences, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen, United Kingdom.

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http://dx.doi.org/10.1016/S0076-6879(07)28003-6DOI Listing
November 2007

The role of tryptophan residues in the function and stability of the mechanosensitive channel MscS from Escherichia coli.

Biochemistry 2007 Sep 24;46(38):10899-908. Epub 2007 Aug 24.

School of Medical Sciences, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen, AB25 2ZD, UK.

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http://pubs.acs.org/doi/abs/10.1021/bi701056k
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http://dx.doi.org/10.1021/bi701056kDOI Listing
September 2007

Mechanosensitive channels in bacteria: signs of closure?

Nat Rev Microbiol 2007 Jun;5(6):431-40

School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, UK.

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http://dx.doi.org/10.1038/nrmicro1659DOI Listing
June 2007

Menopause symptoms in HIV-infected and drug-using women.

Menopause 2005 May-Jun;12(3):348-56

Albert Einstein College of Medicine at Montefiore Medical Center, Bronx, New York 10467, USA.

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http://dx.doi.org/10.1097/01.gme.0000141981.88782.38DOI Listing
May 2006

Pivotal role of the glycine-rich TM3 helix in gating the MscS mechanosensitive channel.

Nat Struct Mol Biol 2005 Feb 23;12(2):113-9. Epub 2005 Jan 23.

School of Medical Sciences, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen, AB25 2ZD, UK.

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http://dx.doi.org/10.1038/nsmb895DOI Listing
February 2005

Gating the bacterial mechanosensitive channels: MscS a new paradigm?

Curr Opin Microbiol 2004 Apr;7(2):163-7

School of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, Scotland, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S136952740400019
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http://dx.doi.org/10.1016/j.mib.2004.02.006DOI Listing
April 2004

A role for mechanosensitive channels in survival of stationary phase: regulation of channel expression by RpoS.

Proc Natl Acad Sci U S A 2003 Dec 11;100(26):15959-64. Epub 2003 Dec 11.

Department of Molecular and Cell Biology, Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, Scotland, United Kingdom.

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http://dx.doi.org/10.1073/pnas.2536607100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC307675PMC
December 2003

Bacterial ion channels.

Biochemistry 2003 Sep;42(34):10045-53

Department of Molecular and Cell Biology, Institute of Medical Sciences, Foresterhill, Aberdeen AB25 2ZD, UK.

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http://dx.doi.org/10.1021/bi034953wDOI Listing
September 2003

The closed structure of the MscS mechanosensitive channel. Cross-linking of single cysteine mutants.

J Biol Chem 2003 Aug 26;278(34):32246-50. Epub 2003 May 26.

Department of Molecular & Cell Biology, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M303188200DOI Listing
August 2003

Risk and protective factors for juvenile eating disorders.

Eur Child Adolesc Psychiatry 2003 ;12 Suppl 1:I38-6

Division of Child Psychiatry and Child Development, Stanford University, School of Medicine, 401 Quarry Road, Stanford, CA 94305-5719, USA.

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http://dx.doi.org/10.1007/s00787-003-1106-8DOI Listing
July 2003

The stress response in anorexia nervosa.

Child Psychiatry Hum Dev 2003 ;33(4):295-306

Stanford University, CA 94305, USA.

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http://dx.doi.org/10.1023/a:1023036329399DOI Listing
May 2003

Two families of mechanosensitive channel proteins.

Microbiol Mol Biol Rev 2003 Mar;67(1):66-85, table of contents

Division of Biology, University of California San Diego, La Jolla, California 92093-0116, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC150521PMC
http://dx.doi.org/10.1128/mmbr.67.1.66-85.2003DOI Listing
March 2003

Domain organization of the MscS mechanosensitive channel of Escherichia coli.

EMBO J 2003 Jan;22(1):36-46

Department of Molecular and Cell Biology, University of Aberdeen, Institute of Medical Sciences, Aberdeen AB25 2ZD, UK.

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http://dx.doi.org/10.1093/emboj/cdg011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC140058PMC
January 2003

A mechanism of regulating transmembrane potassium flux through a ligand-mediated conformational switch.

Cell 2002 Jun;109(6):781-91

Structural Biology Laboratory, Salk Institute and Division of Biology, University of California, San Diego, 92037, USA.

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http://dx.doi.org/10.1016/s0092-8674(02)00768-7DOI Listing
June 2002