Samantha E Greasley

Samantha E Greasley

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Samantha E Greasley

Samantha E Greasley

Publications by authors named "Samantha E Greasley"

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8Publications

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Insights into mechanism of glucokinase activation: observation of multiple distinct protein conformations.

J Biol Chem 2012 Apr 1;287(17):13598-610. Epub 2012 Feb 1.

Structural Biology and Biophysics, Pfizer Groton Laboratories, Groton, Connecticut 06340, USA.

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http://dx.doi.org/10.1074/jbc.M111.274126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340189PMC
April 2012

Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates.

J Biol Chem 2004 Apr 13;279(17):18034-45. Epub 2004 Feb 13.

Department of Molecular Biology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1074/jbc.M313691200DOI Listing
April 2004

Structural insights into the human and avian IMP cyclohydrolase mechanism via crystal structures with the bound XMP inhibitor.

Biochemistry 2004 Feb;43(5):1171-83

Department of Molecular Biology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1021/bi030162iDOI Listing
February 2004

Structure of avian AICAR transformylase with a multisubstrate adduct inhibitor beta-DADF identifies the folate binding site.

Biochemistry 2003 Sep;42(37):10904-14

The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1021/bi030106hDOI Listing
September 2003

Crystal structures of human GAR Tfase at low and high pH and with substrate beta-GAR.

Biochemistry 2002 Dec;41(48):14206-15

Department of Molecular Biology, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1021/bi020522mDOI Listing
December 2002

Structural insights into the avian AICAR transformylase mechanism.

Biochemistry 2002 Dec;41(52):15505-13

Department of Molecular Biology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1021/bi020505xDOI Listing
December 2002