Sam Noppen

Sam Noppen

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Sam Noppen

Sam Noppen

Publications by authors named "Sam Noppen"

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Influenza virus entry via the GM3 ganglioside-mediated platelet-derived growth factor receptor β signalling pathway.

J Gen Virol 2019 Apr 14;100(4):583-601. Epub 2019 Feb 14.

1​Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1099/jgv.0.001235DOI Listing
April 2019

CCL20, a direct-acting pro-angiogenic chemokine induced by hepatitis C virus (HCV): Potential role in HCV-related liver cancer.

Exp Cell Res 2018 Nov 2;372(2):168-177. Epub 2018 Oct 2.

Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, University of Leuven (KU Leuven), Belgium.

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https://linkinghub.elsevier.com/retrieve/pii/S00144827183043
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http://dx.doi.org/10.1016/j.yexcr.2018.09.023DOI Listing
November 2018

Synthesis of a 3'-C-ethynyl-β-d-ribofuranose purine nucleoside library: Discovery of C7-deazapurine analogs as potent antiproliferative nucleosides.

Eur J Med Chem 2018 Sep 29;157:248-267. Epub 2018 Jul 29.

Laboratory for Medicinal Chemistry (Campus Heymans), Ghent University, Ottergemsesteenweg 460, B-9000, Gent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.07.062DOI Listing
September 2018

Modulation of BACE1 Activity by Chemically Modified Aptamers.

Chembiochem 2018 04 19;19(7):754-763. Epub 2018 Feb 19.

Univ Evry, CNRS-UMR8030-Laboratoire iSSB, CEA, DRF, IG, Genoscope, Université Paris-Saclay, 5 rue Henri Desbruères, Évry, 91030, France.

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http://dx.doi.org/10.1002/cbic.201700461DOI Listing
April 2018

Conformational mimetics of the α-methyl chalcone TUB091 binding tubulin: Design, synthesis and antiproliferative activity.

Eur J Med Chem 2018 Mar 10;148:337-348. Epub 2018 Feb 10.

Instituto de Química Médica (IQM, CSIC), Juan de la Cierva 3, E-28006 Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.02.019DOI Listing
March 2018

An allosteric binding site of the α7 nicotinic acetylcholine receptor revealed in a humanized acetylcholine-binding protein.

J Biol Chem 2018 02 13;293(7):2534-2545. Epub 2017 Dec 13.

From the Department of Cellular and Molecular Medicine, Laboratory of Structural Neurobiology, Faculty of Medicine, KU Leuven, 3000 Leuven, Belgium,

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http://dx.doi.org/10.1074/jbc.M117.815316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818190PMC
February 2018

New findings on the d(TGGGAG) sequence: Surprising anti-HIV-1 activity.

Eur J Med Chem 2018 Feb 5;145:425-430. Epub 2018 Jan 5.

Department of Chemical Sciences, University of Napoli 'Federico II', Via Cintia 4, I-80126, Napoli, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.01.005DOI Listing
February 2018

Interferon lambda (IFN-λ) efficiently blocks norovirus transmission in a mouse model.

Antiviral Res 2018 01 10;149:7-15. Epub 2017 Nov 10.

KU Leuven - University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01663542173060
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http://dx.doi.org/10.1016/j.antiviral.2017.10.017DOI Listing
January 2018

Truncation of CXCL12 by CD26 reduces its CXC chemokine receptor 4- and atypical chemokine receptor 3-dependent activity on endothelial cells and lymphocytes.

Biochem Pharmacol 2017 05 18;132:92-101. Epub 2017 Mar 18.

KU Leuven, University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Molecular Immunology, B-3000 Leuven, Belgium. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00062952173013
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http://dx.doi.org/10.1016/j.bcp.2017.03.009DOI Listing
May 2017

Bioluminescent avian pathogenic Escherichia coli for monitoring colibacillosis in experimentally infected chickens.

Vet J 2016 Oct 20;216:87-92. Epub 2016 Jul 20.

Department of Biosystems, Division of Gene Technology, Katholieke Universiteit Leuven, Kasteelpark Arenberg 30, Leuven 3000, Belgium.

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http://dx.doi.org/10.1016/j.tvjl.2016.07.011DOI Listing
October 2016

Basic chemokine-derived glycosaminoglycan binding peptides exert antiviral properties against dengue virus serotype 2, herpes simplex virus-1 and respiratory syncytial virus.

Biochem Pharmacol 2016 Jan 10;100:73-85. Epub 2015 Nov 10.

KU Leuven, University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Molecular Immunology, B-3000 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2015.11.001DOI Listing
January 2016

Antiviral Activity of Synthetic Aminopyrrolic Carbohydrate Binding Agents: Targeting the Glycans of Viral gp120 to Inhibit HIV Entry.

Chemistry 2015 Jul 1;21(28):10089-93. Epub 2015 Jun 1.

Istituto di Metodologie Chimiche (IMC), Consiglio Nazionale delle Ricerche (CNR), Dipartimento di Chimica, Polo Scientifico e Tecnologico, 50019 Sesto Fiorentino, Firenze (Italy).

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http://dx.doi.org/10.1002/chem.201501030DOI Listing
July 2015

Hairpin oligonucleotides forming G-quadruplexes: new aptamers with anti-HIV activity.

Eur J Med Chem 2015 Jan 14;89:51-8. Epub 2014 Oct 14.

Department of Chemical Sciences, University of Napoli 'Federico II', Via Cintia 4, I-80126 Napoli, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2014.10.030DOI Listing
January 2015

Signal peptide-binding drug as a selective inhibitor of co-translational protein translocation.

PLoS Biol 2014 Dec 2;12(12):e1002011. Epub 2014 Dec 2.

MRC-Laboratory for Molecular Cell Biology, University College London, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pbio.1002011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251836PMC
December 2014

Broad anti-HIV activity of the Oscillatoria agardhii agglutinin homologue lectin family.

J Antimicrob Chemother 2014 Oct 25;69(10):2746-58. Epub 2014 Jun 25.

Rega Institute for Medical Research, University of Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1093/jac/dku220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164143PMC
October 2014

Nucleoside-catabolizing enzymes in mycoplasma-infected tumor cell cultures compromise the cytostatic activity of the anticancer drug gemcitabine.

J Biol Chem 2014 May 25;289(19):13054-65. Epub 2014 Mar 25.

From the Rega Institute for Medical Research, KU Leuven, Minderbroedersstraat 10, blok x-bus 1030, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1074/jbc.M114.558924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036319PMC
May 2014

Novel colchicine-site binders with a cyclohexanedione scaffold identified through a ligand-based virtual screening approach.

J Med Chem 2014 May 9;57(10):3924-38. Epub 2014 May 9.

Instituto de Química Médica (IQM-CSIC) , Juan de la Cierva 3, E-28006 Madrid, Spain.

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http://dx.doi.org/10.1021/jm401939gDOI Listing
May 2014

Inhibition of infection and transmission of HIV-1 and lack of significant impact on the vaginal commensal lactobacilli by carbohydrate-binding agents.

J Antimicrob Chemother 2013 Sep 2;68(9):2026-37. Epub 2013 May 2.

Centre of Microbial and Plant Genetics, KU Leuven, Kasteelpark Arenberg 20, bus 2460, B-3001 Leuven, Belgium.

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http://dx.doi.org/10.1093/jac/dkt152DOI Listing
September 2013

Hemozoin induces lung inflammation and correlates with malaria-associated acute respiratory distress syndrome.

Am J Respir Cell Mol Biol 2013 May;48(5):589-600

Laboratory of Immunobiology, Department of Microbiology and Immunology, Rega Institute for Medical Research, KU Leuven–University of Leuven, Leuven 3000, Belgium.

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http://dx.doi.org/10.1165/rcmb.2012-0450OCDOI Listing
May 2013

Neutrophil extracellular trap cell death requires both autophagy and superoxide generation.

Cell Res 2011 Feb 9;21(2):290-304. Epub 2010 Nov 9.

IRC - Laboratory of Biochemistry, Department of Medicine, KU Leuven Campus Kortrijk, Kortrijk, Belgium.

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http://dx.doi.org/10.1038/cr.2010.150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193439PMC
February 2011