Salvatore Oddo

Salvatore Oddo

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Salvatore Oddo

Publications by authors named "Salvatore Oddo"

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Lifelong choline supplementation ameliorates Alzheimer's disease pathology and associated cognitive deficits by attenuating microglia activation.

Aging Cell 2019 Sep 27:e13037. Epub 2019 Sep 27.

Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, AZ, USA.

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http://dx.doi.org/10.1111/acel.13037DOI Listing
September 2019

Differential activation of the mTOR/autophagy pathway predicts cognitive performance in APP/PS1 mice.

Neurobiol Aging 2019 Sep 3;83:105-113. Epub 2019 Sep 3.

Arizona State University-Banner Neurodegenerative Disease Research Center, Biodesign Institute, Arizona State University, Tempe, AZ, USA; School of Life Sciences, Arizona State University, Tempe, AZ, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.08.018DOI Listing
September 2019

Temporal and regional progression of Alzheimer's disease-like pathology in 3xTg-AD mice.

Aging Cell 2019 Feb 28;18(1):e12873. Epub 2018 Nov 28.

The Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, Arizona.

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http://dx.doi.org/10.1111/acel.12873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351836PMC
February 2019

Maternal choline supplementation ameliorates Alzheimer's disease pathology by reducing brain homocysteine levels across multiple generations.

Mol Psychiatry 2019 Jan 8. Epub 2019 Jan 8.

Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, AZ, USA.

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http://dx.doi.org/10.1038/s41380-018-0322-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697226PMC
January 2019

Genetically reducing mTOR signaling rescues central insulin dysregulation in a mouse model of Alzheimer's disease.

Neurobiol Aging 2018 08 5;68:59-67. Epub 2018 Apr 5.

The Arizona State University-Banner, Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, AZ, USA; School of Life Sciences, Arizona State University, Tempe, AZ, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.03.032DOI Listing
August 2018

Acute tau knockdown in the hippocampus of adult mice causes learning and memory deficits.

Aging Cell 2018 08 10;17(4):e12775. Epub 2018 May 10.

Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, AZ, USA.

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http://doi.wiley.com/10.1111/acel.12775
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http://dx.doi.org/10.1111/acel.12775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052471PMC
August 2018

Genetic reduction of Nrf2 exacerbates cognitive deficits in a mouse model of Alzheimer's disease.

Hum Mol Genet 2017 12;26(24):4823-4835

Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.

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http://dx.doi.org/10.1093/hmg/ddx361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886066PMC
December 2017

Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease.

Neurobiol Aging 2017 10 17;58:1-13. Epub 2017 Jun 17.

Department of Neurology, Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch at Galveston (UTMB), Galveston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819888PMC
October 2017

Dyrk1 inhibition improves Alzheimer's disease-like pathology.

Aging Cell 2017 10 4;16(5):1146-1154. Epub 2017 Aug 4.

The Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA.

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http://dx.doi.org/10.1111/acel.12648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595697PMC
October 2017

Necroptosis activation in Alzheimer's disease.

Nat Neurosci 2017 Sep 24;20(9):1236-1246. Epub 2017 Jul 24.

Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, Arizona, USA.

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http://dx.doi.org/10.1038/nn.4608DOI Listing
September 2017

mTOR and neuronal cell cycle reentry: How impaired brain insulin signaling promotes Alzheimer's disease.

Alzheimers Dement 2017 02 29;13(2):152-167. Epub 2016 Sep 29.

Department of Biology, University of Virginia, Charlottesville, VA, USA; Department of Cell Biology, University of Virginia, Charlottesville, VA, USA; Department of Neuroscience, University of Virginia, Charlottesville, VA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2016.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318248PMC
February 2017

Paving the Way for New Clinical Trials for Alzheimer's Disease.

Biol Psychiatry 2017 01;81(2):88-89

School of Life Sciences, Arizona State University, Tempe, Arizona. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2016.10.016DOI Listing
January 2017

Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease.

Mol Neurodegener 2016 07 13;11(1):52. Epub 2016 Jul 13.

Neurodegenerative Disease Research Center, Biodesign Institute, School of Life Sciences, Arizona State University, 727 E. Tyler Street, Tempe, AZ, 85287-5001, USA.

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http://dx.doi.org/10.1186/s13024-016-0118-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944476PMC
July 2016

Aberrant intracellular localization of H3k4me3 demonstrates an early epigenetic phenomenon in Alzheimer's disease.

Neurobiol Aging 2015 Dec 10;36(12):3121-3129. Epub 2015 Sep 10.

ASU-Banner Neurodegenerative Disease Research Center, Biodesign Institute and School of Life Sciences, Arizona State University, Tempe, AZ, USA; L.J. Roberts Alzheimer's Disease Center, Banner Sun Health Research Institute, Sun City, AZ, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.08.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838454PMC
December 2015

The mammalian target of rapamycin at the crossroad between cognitive aging and Alzheimer's disease.

NPJ Aging Mech Dis 2015 15;1:15008. Epub 2015 Oct 15.

Banner Sun Health Research Institute, Sun City, AZ, USA.

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http://dx.doi.org/10.1038/npjamd.2015.8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514987PMC
October 2015

How longevity research can lead to therapies for Alzheimer's disease: The rapamycin story.

Exp Gerontol 2015 Aug 3;68:51-8. Epub 2014 Dec 3.

Banner Sun Health Research Institute, Sun City, AZ 85351, USA; Department of Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1016/j.exger.2014.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417920PMC
August 2015

Reduced protein turnover mediates functional deficits in transgenic mice expressing the 25 kDa C-terminal fragment of TDP-43.

Hum Mol Genet 2015 Aug 22;24(16):4625-35. Epub 2015 May 22.

Banner Sun Health Research Institute, Sun City, AZ 85351, USA, Department of Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, Phoenix, AZ 85004, USA

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http://dx.doi.org/10.1093/hmg/ddv193DOI Listing
August 2015

Administration of a selective β2 adrenergic receptor antagonist exacerbates neuropathology and cognitive deficits in a mouse model of Alzheimer's disease.

Neurobiol Aging 2014 Dec 16;35(12):2726-2735. Epub 2014 Jun 16.

Banner Sun Health Research Institute, Sun City, AZ, USA; Department of Basic Medical Sciences, University of Arizona College of Medicine at Phoenix, Phoenix, AZ, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252846PMC
December 2014

Genetic suppression of β2-adrenergic receptors ameliorates tau pathology in a mouse model of tauopathies.

Hum Mol Genet 2014 Aug 13;23(15):4024-34. Epub 2014 Mar 13.

Department of Physiology and The Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA Banner Sun Health Research Institute, Sun City, AZ, USA Department of Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, Sun City, AZ, USA

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http://dx.doi.org/10.1093/hmg/ddu116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082366PMC
August 2014

Autophagic/lysosomal dysfunction in Alzheimer's disease.

Alzheimers Res Ther 2013 29;5(5):53. Epub 2013 Oct 29.

Department of Physiology and The Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA ; Banner Sun Health Research Institute and Department of Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, 10515 W. Santa Fe Drive, Sun City, AZ 85351, USA.

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http://dx.doi.org/10.1186/alzrt217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979020PMC
June 2014

Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology.

Neurobiol Aging 2014 Jun 14;35(6):1233-42. Epub 2013 Dec 14.

Department of Physiology and The Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; Banner Sun Health Research Institute, Sun City, AZ, USA; Department of Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973159PMC
June 2014

Genetic reduction of mammalian target of rapamycin ameliorates Alzheimer's disease-like cognitive and pathological deficits by restoring hippocampal gene expression signature.

J Neurosci 2014 Jun;34(23):7988-98

Banner Sun Health Research Institute, Sun City, Arizona 85351, Department of Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, Phoenix, Arizona 85004

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http://dx.doi.org/10.1523/JNEUROSCI.0777-14.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044255PMC
June 2014

Oxidative damage and amyloid-β metabolism in brain regions of the longest-lived rodents.

J Neurosci Res 2014 Feb 22;92(2):195-205. Epub 2013 Nov 22.

Department of Physiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas; The Barshop Institute for Aging and Longevity Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas.

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http://dx.doi.org/10.1002/jnr.23320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838185PMC
February 2014

Accumulation of C-terminal fragments of transactive response DNA-binding protein 43 leads to synaptic loss and cognitive deficits in human TDP-43 transgenic mice.

Neurobiol Aging 2014 Jan 15;35(1):79-87. Epub 2013 Aug 15.

Department of Physiology and The Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.07.006DOI Listing
January 2014

Amyloid beta and the longest-lived rodent: the naked mole-rat as a model for natural protection from Alzheimer's disease.

Neurobiol Aging 2013 Oct 22;34(10):2352-60. Epub 2013 Apr 22.

Department of Physiology, University of Texas Health Science Center, San Antonio, TX 78229, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.03.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496028PMC
October 2013

mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies.

Aging Cell 2013 Jun 24;12(3):370-80. Epub 2013 Mar 24.

Department of Physiology and The Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.

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http://dx.doi.org/10.1111/acel.12057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655115PMC
June 2013

β2 adrenergic receptor, protein kinase A (PKA) and c-Jun N-terminal kinase (JNK) signaling pathways mediate tau pathology in Alzheimer disease models.

J Biol Chem 2013 Apr 19;288(15):10298-307. Epub 2013 Feb 19.

Department of Molecular and Integrative Physiology, School of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

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http://dx.doi.org/10.1074/jbc.M112.415141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624413PMC
April 2013

Glucocorticoids exacerbate cognitive deficits in TDP-25 transgenic mice via a glutathione-mediated mechanism: implications for aging, stress and TDP-43 proteinopathies.

J Neurosci 2013 Jan;33(3):906-13

Department of Physiology and The Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.3314-12.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704880PMC
January 2013

Sortilin is required for toxic action of Aβ oligomers (AβOs): extracellular AβOs trigger apoptosis, and intraneuronal AβOs impair degradation pathways.

Life Sci 2012 Dec 3;91(23-24):1177-86. Epub 2012 May 3.

Department of Neurology, Institute of Brain Science, Hirosaki University Graduate School of Medicine, Aomori, Japan.

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http://dx.doi.org/10.1016/j.lfs.2012.04.038DOI Listing
December 2012

Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling.

Aging Cell 2012 Apr 1;11(2):326-35. Epub 2012 Feb 1.

Department of Physiology, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229-3900, USA.

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http://dx.doi.org/10.1111/j.1474-9726.2011.00791.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306461PMC
April 2012

Guidelines for the use and interpretation of assays for monitoring autophagy.

Authors:
Daniel J Klionsky Fabio C Abdalla Hagai Abeliovich Robert T Abraham Abraham Acevedo-Arozena Khosrow Adeli Lotta Agholme Maria Agnello Patrizia Agostinis Julio A Aguirre-Ghiso Hyung Jun Ahn Ouardia Ait-Mohamed Slimane Ait-Si-Ali Takahiko Akematsu Shizuo Akira Hesham M Al-Younes Munir A Al-Zeer Matthew L Albert Roger L Albin Javier Alegre-Abarrategui Maria Francesca Aleo Mehrdad Alirezaei Alexandru Almasan Maylin Almonte-Becerril Atsuo Amano Ravi Amaravadi Shoba Amarnath Amal O Amer Nathalie Andrieu-Abadie Vellareddy Anantharam David K Ann Shailendra Anoopkumar-Dukie Hiroshi Aoki Nadezda Apostolova Giuseppe Arancia John P Aris Katsuhiko Asanuma Nana Y O Asare Hisashi Ashida Valerie Askanas David S Askew Patrick Auberger Misuzu Baba Steven K Backues Eric H Baehrecke Ben A Bahr Xue-Yuan Bai Yannick Bailly Robert Baiocchi Giulia Baldini Walter Balduini Andrea Ballabio Bruce A Bamber Edward T W Bampton Gábor Bánhegyi Clinton R Bartholomew Diane C Bassham Robert C Bast Henri Batoko Boon-Huat Bay Isabelle Beau Daniel M Béchet Thomas J Begley Christian Behl Christian Behrends Soumeya Bekri Bryan Bellaire Linda J Bendall Luca Benetti Laura Berliocchi Henri Bernardi Francesca Bernassola Sébastien Besteiro Ingrid Bhatia-Kissova Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Lawrence H Boise Paolo Bonaldo David L Boone Beat C Bornhauser Karina R Bortoluci Ioannis Bossis Frédéric Bost Jean-Pierre Bourquin Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan R Brady Claudio Brancolini Andreas Brech Jay E Brenman Ana Brennand Emery H Bresnick Patrick Brest Dave Bridges Molly L Bristol Paul S Brookes Eric J Brown John H Brumell Nicola Brunetti-Pierri Ulf T Brunk Dennis E Bulman Scott J Bultman Geert Bultynck Lena F Burbulla Wilfried Bursch Jonathan P Butchar Wanda Buzgariu Sergio P Bydlowski Ken Cadwell Monika Cahová Dongsheng Cai Jiyang Cai Qian Cai Bruno Calabretta Javier Calvo-Garrido Nadine Camougrand Michelangelo Campanella Jenny Campos-Salinas Eleonora Candi Lizhi Cao Allan B Caplan Simon R Carding Sandra M Cardoso Jennifer S Carew Cathleen R Carlin Virginie Carmignac Leticia A M Carneiro Serena Carra Rosario A Caruso Giorgio Casari Caty Casas Roberta Castino Eduardo Cebollero Francesco Cecconi Jean Celli Hassan Chaachouay Han-Jung Chae Chee-Yin Chai David C Chan Edmond Y Chan Raymond Chuen-Chung Chang Chi-Ming Che Ching-Chow Chen Guang-Chao Chen Guo-Qiang Chen Min Chen Quan Chen Steve S-L Chen WenLi Chen Xi Chen Xiangmei Chen Xiequn Chen Ye-Guang Chen Yingyu Chen Yongqiang Chen Yu-Jen Chen Zhixiang Chen Alan Cheng Christopher H K Cheng Yan Cheng Heesun Cheong Jae-Ho Cheong Sara Cherry Russ Chess-Williams Zelda H Cheung Eric Chevet Hui-Ling Chiang Roberto Chiarelli Tomoki Chiba Lih-Shen Chin Shih-Hwa Chiou Francis V Chisari Chi Hin Cho Dong-Hyung Cho Augustine M K Choi DooSeok Choi Kyeong Sook Choi Mary E Choi Salem Chouaib Divaker Choubey Vinay Choubey Charleen T Chu Tsung-Hsien Chuang Sheau-Huei Chueh Taehoon Chun Yong-Joon Chwae Mee-Len Chye Roberto Ciarcia Maria R Ciriolo Michael J Clague Robert S B Clark Peter G H Clarke Robert Clarke Patrice Codogno Hilary A Coller María I Colombo Sergio Comincini Maria Condello Fabrizio Condorelli Mark R Cookson Graham H Coombs Isabelle Coppens Ramon Corbalan Pascale Cossart Paola Costelli Safia Costes Ana Coto-Montes Eduardo Couve Fraser P Coxon James M Cregg José L Crespo Marianne J Cronjé Ana Maria Cuervo Joseph J Cullen Mark J Czaja Marcello D'Amelio Arlette Darfeuille-Michaud Lester M Davids Faith E Davies Massimo De Felici John F de Groot Cornelis A M de Haan Luisa De Martino Angelo De Milito Vincenzo De Tata Jayanta Debnath Alexei Degterev Benjamin Dehay Lea M D Delbridge Francesca Demarchi Yi Zhen Deng Jörn Dengjel Paul Dent Donna Denton Vojo Deretic Shyamal D Desai Rodney J Devenish Mario Di Gioacchino Gilbert Di Paolo Chiara Di Pietro Guillermo Díaz-Araya Inés Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Ivan Dikic Savithramma P Dinesh-Kumar Wen-Xing Ding Clark W Distelhorst Abhinav Diwan Mojgan Djavaheri-Mergny Svetlana Dokudovskaya Zheng Dong Frank C Dorsey Victor Dosenko James J Dowling Stephen Doxsey Marlène Dreux Mark E Drew Qiuhong Duan Michel A Duchosal Karen Duff Isabelle Dugail Madeleine Durbeej Michael Duszenko Charles L Edelstein Aimee L Edinger Gustavo Egea Ludwig Eichinger N Tony Eissa Suhendan Ekmekcioglu Wafik S El-Deiry Zvulun Elazar Mohamed Elgendy Lisa M Ellerby Kai Er Eng Anna-Mart Engelbrecht Simone Engelender Jekaterina Erenpreisa Ricardo Escalante Audrey Esclatine Eeva-Liisa Eskelinen Lucile Espert Virginia Espina Huizhou Fan Jia Fan Qi-Wen Fan Zhen Fan Shengyun Fang Yongqi Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Jean-Claude Farré Mathias Faure Marcus Fechheimer Carl G Feng Jian Feng Qili Feng Youji Feng László Fésüs Ralph Feuer Maria E Figueiredo-Pereira Gian Maria Fimia Diane C Fingar Steven Finkbeiner Toren Finkel Kim D Finley Filomena Fiorito Edward A Fisher Paul B Fisher Marc Flajolet Maria L Florez-McClure Salvatore Florio Edward A Fon Francesco Fornai Franco Fortunato Rati Fotedar Daniel H Fowler Howard S Fox Rodrigo Franco Lisa B Frankel Marc Fransen José M Fuentes Juan Fueyo Jun Fujii Kozo Fujisaki Eriko Fujita Mitsunori Fukuda Ruth H Furukawa Matthias Gaestel Philippe Gailly Malgorzata Gajewska Brigitte Galliot Vincent Galy Subramaniam Ganesh Barry Ganetzky Ian G Ganley Fen-Biao Gao George F Gao Jinming Gao Lorena Garcia Guillermo Garcia-Manero Mikel Garcia-Marcos Marjan Garmyn Andrei L Gartel Evelina Gatti Mathias Gautel Thomas R Gawriluk Matthew E Gegg Jiefei Geng Marc Germain Jason E Gestwicki David A Gewirtz Saeid Ghavami Pradipta Ghosh Anna M Giammarioli Alexandra N Giatromanolaki Spencer B Gibson Robert W Gilkerson Michael L Ginger Henry N Ginsberg Jakub Golab Michael S Goligorsky Pierre Golstein Candelaria Gomez-Manzano Ebru Goncu Céline Gongora Claudio D Gonzalez Ramon Gonzalez Cristina González-Estévez Rosa Ana González-Polo Elena Gonzalez-Rey Nikolai V Gorbunov Sharon Gorski Sandro Goruppi Roberta A Gottlieb Devrim Gozuacik Giovanna Elvira Granato Gary D Grant Kim N Green Aleš Gregorc Frédéric Gros Charles Grose Thomas W Grunt Philippe Gual Jun-Lin Guan Kun-Liang Guan Sylvie M Guichard Anna S Gukovskaya Ilya Gukovsky Jan Gunst Asa B Gustafsson Andrew J Halayko Amber N Hale Sandra K Halonen Maho Hamasaki Feng Han Ting Han Michael K Hancock Malene Hansen Hisashi Harada Masaru Harada Stefan E Hardt J Wade Harper Adrian L Harris James Harris Steven D Harris Makoto Hashimoto Jeffrey A Haspel Shin-ichiro Hayashi Lori A Hazelhurst Congcong He You-Wen He Marie-Joseé Hébert Kim A Heidenreich Miep H Helfrich Gudmundur V Helgason Elizabeth P Henske Brian Herman Paul K Herman Claudio Hetz Sabine Hilfiker Joseph A Hill Lynne J Hocking Paul Hofman Thomas G Hofmann Jörg Höhfeld Tessa L Holyoake Ming-Huang Hong David A Hood Gökhan S Hotamisligil Ewout J Houwerzijl Maria Høyer-Hansen Bingren Hu Chien-An A Hu Hong-Ming Hu Ya Hua Canhua Huang Ju Huang Shengbing Huang Wei-Pang Huang Tobias B Huber Won-Ki Huh Tai-Ho Hung Ted R Hupp Gang Min Hur James B Hurley Sabah N A Hussain Patrick J Hussey Jung Jin Hwang Seungmin Hwang Atsuhiro Ichihara Shirin Ilkhanizadeh Ken Inoki Takeshi Into Valentina Iovane Juan L Iovanna Nancy Y Ip Yoshitaka Isaka Hiroyuki Ishida Ciro Isidoro Ken-ichi Isobe Akiko Iwasaki Marta Izquierdo Yotaro Izumi Panu M Jaakkola Marja Jäättelä George R Jackson William T Jackson Bassam Janji Marina Jendrach Ju-Hong Jeon Eui-Bae Jeung Hong Jiang Hongchi Jiang Jean X Jiang Ming Jiang Qing Jiang Xuejun Jiang Xuejun Jiang Alberto Jiménez Meiyan Jin Shengkan Jin Cheol O Joe Terje Johansen Daniel E Johnson Gail V W Johnson Nicola L Jones Bertrand Joseph Suresh K Joseph Annie M Joubert Gábor Juhász Lucienne Juillerat-Jeanneret Chang Hwa Jung Yong-Keun Jung Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Motoni Kadowaki Katarina Kagedal Yoshiaki Kamada Vitaliy O Kaminskyy Harm H Kampinga Hiromitsu Kanamori Chanhee Kang Khong Bee Kang Kwang Il Kang Rui Kang Yoon-A Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Arthi Kanthasamy Vassiliki Karantza Gur P Kaushal Susmita Kaushik Yoshinori Kawazoe Po-Yuan Ke John H Kehrl Ameeta Kelekar Claus Kerkhoff David H Kessel Hany Khalil Jan A K W Kiel Amy A Kiger Akio Kihara Deok Ryong Kim Do-Hyung Kim Dong-Hou Kim Eun-Kyoung Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim John K Kim Peter K Kim Seong Who Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Jason S King Timothy J Kinsella Vladimir Kirkin Lorrie A Kirshenbaum Katsuhiko Kitamoto Kaio Kitazato Ludger Klein Walter T Klimecki Jochen Klucken Erwin Knecht Ben C B Ko Jan C Koch Hiroshi Koga Jae-Young Koh Young Ho Koh Masato Koike Masaaki Komatsu Eiki Kominami Hee Jeong Kong Wei-Jia Kong Viktor I Korolchuk Yaichiro Kotake Michael I Koukourakis Juan B Kouri Flores Attila L Kovács Claudine Kraft Dimitri Krainc Helmut Krämer Carole Kretz-Remy Anna M Krichevsky Guido Kroemer Rejko Krüger Oleg Krut Nicholas T Ktistakis Chia-Yi Kuan Roza Kucharczyk Ashok Kumar Raj Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Tino Kurz Ho Jeong Kwon Albert R La Spada Frank Lafont Trond Lamark Jacques Landry Jon D Lane Pierre Lapaquette Jocelyn F Laporte Lajos László Sergio Lavandero Josée N Lavoie Robert Layfield Pedro A Lazo Weidong Le Laurent Le Cam Daniel J Ledbetter Alvin J X Lee Byung-Wan Lee Gyun Min Lee Jongdae Lee Ju-Hyun Lee Michael Lee Myung-Shik Lee Sug Hyung Lee Christiaan Leeuwenburgh Patrick Legembre Renaud Legouis Michael Lehmann Huan-Yao Lei Qun-Ying Lei David A Leib José Leiro John J Lemasters Antoinette Lemoine Maciej S Lesniak Dina Lev Victor V Levenson Beth Levine Efrat Levy Faqiang Li Jun-Lin Li Lian Li Sheng Li Weijie Li Xue-Jun Li Yan-bo Li Yi-Ping Li Chengyu Liang Qiangrong Liang Yung-Feng Liao Pawel P Liberski Andrew Lieberman Hyunjung J Lim Kah-Leong Lim Kyu Lim Chiou-Feng Lin Fu-Cheng Lin Jian Lin Jiandie D Lin Kui Lin Wan-Wan Lin Weei-Chin Lin Yi-Ling Lin Rafael Linden Paul Lingor Jennifer Lippincott-Schwartz Michael P Lisanti Paloma B Liton Bo Liu Chun-Feng Liu Kaiyu Liu Leyuan Liu Qiong A Liu Wei Liu Young-Chau Liu Yule Liu Richard A Lockshin Chun-Nam Lok Sagar Lonial Benjamin Loos Gabriel Lopez-Berestein Carlos López-Otín Laura Lossi Michael T Lotze Peter Lőw Binfeng Lu Bingwei Lu Bo Lu Zhen Lu Frédéric Luciano Nicholas W Lukacs Anders H Lund Melinda A Lynch-Day Yong Ma Fernando Macian Jeff P MacKeigan Kay F Macleod Frank Madeo Luigi Maiuri Maria Chiara Maiuri Davide Malagoli May Christine V Malicdan Walter Malorni Na Man Eva-Maria Mandelkow Stéphen Manon Irena Manov Kai Mao Xiang Mao Zixu Mao Philippe Marambaud Daniela Marazziti Yves L Marcel Katie Marchbank Piero Marchetti Stefan J Marciniak Mateus Marcondes Mohsen Mardi Gabriella Marfe Guillermo Mariño Maria Markaki Mark R Marten Seamus J Martin Camille Martinand-Mari Wim Martinet Marta Martinez-Vicente Matilde Masini Paola Matarrese Saburo Matsuo Raffaele Matteoni Andreas Mayer Nathalie M Mazure David J McConkey Melanie J McConnell Catherine McDermott Christine McDonald Gerald M McInerney Sharon L McKenna BethAnn McLaughlin Pamela J McLean Christopher R McMaster G Angus McQuibban Alfred J Meijer Miriam H Meisler Alicia Meléndez Thomas J Melia Gerry Melino Maria A Mena Javier A Menendez Rubem F S Menna-Barreto Manoj B Menon Fiona M Menzies Carol A Mercer Adalberto Merighi Diane E Merry Stefania Meschini Christian G Meyer Thomas F Meyer Chao-Yu Miao Jun-Ying Miao Paul A M Michels Carine Michiels Dalibor Mijaljica Ana Milojkovic Saverio Minucci Clelia Miracco Cindy K Miranti Ioannis Mitroulis Keisuke Miyazawa Noboru Mizushima Baharia Mograbi Simin Mohseni Xavier Molero Bertrand Mollereau Faustino Mollinedo Takashi Momoi Iryna Monastyrska Martha M Monick Mervyn J Monteiro Michael N Moore Rodrigo Mora Kevin Moreau Paula I Moreira Yuji Moriyasu Jorge Moscat Serge Mostowy Jeremy C Mottram Tomasz Motyl Charbel E-H Moussa Sylke Müller Sylviane Muller Karl Münger Christian Münz Leon O Murphy Maureen E Murphy Antonio Musarò Indira Mysorekar Eiichiro Nagata Kazuhiro Nagata Aimable Nahimana Usha Nair Toshiyuki Nakagawa Kiichi Nakahira Hiroyasu Nakano Hitoshi Nakatogawa Meera Nanjundan Naweed I Naqvi Derek P Narendra Masashi Narita Miguel Navarro Steffan T Nawrocki Taras Y Nazarko Andriy Nemchenko Mihai G Netea Thomas P Neufeld Paul A Ney Ioannis P Nezis Huu Phuc Nguyen Daotai Nie Ichizo Nishino Corey Nislow Ralph A Nixon Takeshi Noda Angelika A Noegel Anna Nogalska Satoru Noguchi Lucia Notterpek Ivana Novak Tomoyoshi Nozaki Nobuyuki Nukina Thorsten Nürnberger Beat Nyfeler Keisuke Obara Terry D Oberley Salvatore Oddo Michinaga Ogawa Toya Ohashi Koji Okamoto Nancy L Oleinick F Javier Oliver Laura J Olsen Stefan Olsson Onya Opota Timothy F Osborne Gary K Ostrander Kinya Otsu Jing-hsiung James Ou Mireille Ouimet Michael Overholtzer Bulent Ozpolat Paolo Paganetti Ugo Pagnini Nicolas Pallet Glen E Palmer Camilla Palumbo Tianhong Pan Theocharis Panaretakis Udai Bhan Pandey Zuzana Papackova Issidora Papassideri Irmgard Paris Junsoo Park Ohkmae K Park Jan B Parys Katherine R Parzych Susann Patschan Cam Patterson Sophie Pattingre John M Pawelek Jianxin Peng David H Perlmutter Ida Perrotta George Perry Shazib Pervaiz Matthias Peter Godefridus J Peters Morten Petersen Goran Petrovski James M Phang Mauro Piacentini Philippe Pierre Valérie Pierrefite-Carle Gérard Pierron Ronit Pinkas-Kramarski Antonio Piras Natik Piri Leonidas C Platanias Stefanie Pöggeler Marc Poirot Angelo Poletti Christian Poüs Mercedes Pozuelo-Rubio Mette Prætorius-Ibba Anil Prasad Mark Prescott Muriel Priault Nathalie Produit-Zengaffinen Ann Progulske-Fox Tassula Proikas-Cezanne Serge Przedborski Karin Przyklenk Rosa Puertollano Julien Puyal Shu-Bing Qian Liang Qin Zheng-Hong Qin Susan E Quaggin Nina Raben Hannah Rabinowich Simon W Rabkin Irfan Rahman Abdelhaq Rami Georg Ramm Glenn Randall Felix Randow V Ashutosh Rao Jeffrey C Rathmell Brinda Ravikumar Swapan K Ray Bruce H Reed John C Reed Fulvio Reggiori Anne Régnier-Vigouroux Andreas S Reichert John J Reiners Russel J Reiter Jun Ren José L Revuelta Christopher J Rhodes Konstantinos Ritis Elizete Rizzo Jeffrey Robbins Michel Roberge Hernan Roca Maria C Roccheri Stephane Rocchi H Peter Rodemann Santiago Rodríguez de Córdoba Bärbel Rohrer Igor B Roninson Kirill Rosen Magdalena M Rost-Roszkowska Mustapha Rouis Kasper M A Rouschop Francesca Rovetta Brian P Rubin David C Rubinsztein Klaus Ruckdeschel Edmund B Rucker Assaf Rudich Emil Rudolf Nelson Ruiz-Opazo Rossella Russo Tor Erik Rusten Kevin M Ryan Stefan W Ryter David M Sabatini Junichi Sadoshima Tapas Saha Tatsuya Saitoh Hiroshi Sakagami Yasuyoshi Sakai Ghasem Hoseini Salekdeh Paolo Salomoni Paul M Salvaterra Guy Salvesen Rosa Salvioli Anthony M J Sanchez José A Sánchez-Alcázar Ricardo Sánchez-Prieto Marco Sandri Uma Sankar Poonam Sansanwal Laura Santambrogio Shweta Saran Sovan Sarkar Minnie Sarwal Chihiro Sasakawa Ausra Sasnauskiene Miklós Sass Ken Sato Miyuki Sato Anthony H V Schapira Michael Scharl Hermann M Schätzl Wiep Scheper Stefano Schiaffino Claudio Schneider Marion E Schneider Regine Schneider-Stock Patricia V Schoenlein Daniel F Schorderet Christoph Schüller Gary K Schwartz Luca Scorrano Linda Sealy Per O Seglen Juan Segura-Aguilar Iban Seiliez Oleksandr Seleverstov Christian Sell Jong Bok Seo Duska Separovic Vijayasaradhi Setaluri Takao Setoguchi Carmine Settembre John J Shacka Mala Shanmugam Irving M Shapiro Eitan Shaulian Reuben J Shaw James H Shelhamer Han-Ming Shen Wei-Chiang Shen Zu-Hang Sheng Yang Shi Kenichi Shibuya Yoshihiro Shidoji Jeng-Jer Shieh Chwen-Ming Shih Yohta Shimada Shigeomi Shimizu Takahiro Shintani Orian S Shirihai Gordon C Shore Andriy A Sibirny Stan B Sidhu Beata Sikorska Elaine C M Silva-Zacarin Alison Simmons Anna Katharina Simon Hans-Uwe Simon Cristiano Simone Anne Simonsen David A Sinclair Rajat Singh Debasish Sinha Frank A Sinicrope Agnieszka Sirko Parco M Siu Efthimios Sivridis Vojtech Skop Vladimir P Skulachev Ruth S Slack Soraya S Smaili Duncan R Smith Maria S Soengas Thierry Soldati Xueqin Song Anil K Sood Tuck Wah Soong Federica Sotgia Stephen A Spector Claudia D Spies Wolfdieter Springer Srinivasa M Srinivasula Leonidas Stefanis Joan S Steffan Ruediger Stendel Harald Stenmark Anastasis Stephanou Stephan T Stern Cinthya Sternberg Björn Stork Peter Strålfors Carlos S Subauste Xinbing Sui David Sulzer Jiaren Sun Shi-Yong Sun Zhi-Jun Sun Joseph J Y Sung Kuninori Suzuki Toshihiko Suzuki Michele S Swanson Charles Swanton Sean T Sweeney Lai-King Sy Gyorgy Szabadkai Ira Tabas Heinrich Taegtmeyer Marco Tafani Krisztina Takács-Vellai Yoshitaka Takano Kaoru Takegawa Genzou Takemura Fumihiko Takeshita Nicholas J Talbot Kevin S W Tan Keiji Tanaka Kozo Tanaka Daolin Tang Dingzhong Tang Isei Tanida Bakhos A Tannous Nektarios Tavernarakis Graham S Taylor Gregory A Taylor J Paul Taylor Lance S Terada Alexei Terman Gianluca Tettamanti Karin Thevissen Craig B Thompson Andrew Thorburn Michael Thumm FengFeng Tian Yuan Tian Glauco Tocchini-Valentini Aviva M Tolkovsky Yasuhiko Tomino Lars Tönges Sharon A Tooze Cathy Tournier John Tower Roberto Towns Vladimir Trajkovic Leonardo H Travassos Ting-Fen Tsai Mario P Tschan Takeshi Tsubata Allan Tsung Boris Turk Lorianne S Turner Suresh C Tyagi Yasuo Uchiyama Takashi Ueno Midori Umekawa Rika Umemiya-Shirafuji Vivek K Unni Maria I Vaccaro Enza Maria Valente Greet Van den Berghe Ida J van der Klei Wouter van Doorn Linda F van Dyk Marjolein van Egmond Leo A van Grunsven Peter Vandenabeele Wim P Vandenberghe Ilse Vanhorebeek Eva C Vaquero Guillermo Velasco Tibor Vellai Jose Miguel Vicencio Richard D Vierstra Miquel Vila Cécile Vindis Giampietro Viola Maria Teresa Viscomi Olga V Voitsekhovskaja Clarissa von Haefen Marcela Votruba Keiji Wada Richard Wade-Martins Cheryl L Walker Craig M Walsh Jochen Walter Xiang-Bo Wan Aimin Wang Chenguang Wang Dawei Wang Fan Wang Fen Wang Guanghui Wang Haichao Wang Hong-Gang Wang Horng-Dar Wang Jin Wang Ke Wang Mei Wang Richard C Wang Xinglong Wang Xuejun Wang Ying-Jan Wang Yipeng Wang Zhen Wang Zhigang Charles Wang Zhinong Wang Derick G Wansink Diane M Ward Hirotaka Watada Sarah L Waters Paul Webster Lixin Wei Conrad C Weihl William A Weiss Scott M Welford Long-Ping Wen Caroline A Whitehouse J Lindsay Whitton Alexander J Whitworth Tom Wileman John W Wiley Simon Wilkinson Dieter Willbold Roger L Williams Peter R Williamson Bradly G Wouters Chenghan Wu Dao-Cheng Wu William K K Wu Andreas Wyttenbach Ramnik J Xavier Zhijun Xi Pu Xia Gengfu Xiao Zhiping Xie Zhonglin Xie Da-zhi Xu Jianzhen Xu Liang Xu Xiaolei Xu Ai Yamamoto Akitsugu Yamamoto Shunhei Yamashina Michiaki Yamashita Xianghua Yan Mitsuhiro Yanagida Dun-Sheng Yang Elizabeth Yang Jin-Ming Yang Shi Yu Yang Wannian Yang Wei Yuan Yang Zhifen Yang Meng-Chao Yao Tso-Pang Yao Behzad Yeganeh Wei-Lien Yen Jia-jing Yin Xiao-Ming Yin Ook-Joon Yoo Gyesoon Yoon Seung-Yong Yoon Tomohiro Yorimitsu Yuko Yoshikawa Tamotsu Yoshimori Kohki Yoshimoto Ho Jin You Richard J Youle Anas Younes Li Yu Long Yu Seong-Woon Yu Wai Haung Yu Zhi-Min Yuan Zhenyu Yue Cheol-Heui Yun Michisuke Yuzaki Olga Zabirnyk Elaine Silva-Zacarin David Zacks Eldad Zacksenhaus Nadia Zaffaroni Zahra Zakeri Herbert J Zeh Scott O Zeitlin Hong Zhang Hui-Ling Zhang Jianhua Zhang Jing-Pu Zhang Lin Zhang Long Zhang Ming-Yong Zhang Xu Dong Zhang Mantong Zhao Yi-Fang Zhao Ying Zhao Zhizhuang J Zhao Xiaoxiang Zheng Boris Zhivotovsky Qing Zhong Cong-Zhao Zhou Changlian Zhu Wei-Guo Zhu Xiao-Feng Zhu Xiongwei Zhu Yuangang Zhu Teresa Zoladek Wei-Xing Zong Antonio Zorzano Jürgen Zschocke Brian Zuckerbraun

Autophagy 2012 Apr;8(4):445-544

Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.

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April 2012

Toxic role of K+ channel oxidation in mammalian brain.

J Neurosci 2012 Mar;32(12):4133-44

Department of Physiology and Biophysics, University of Medicine and Dentistry of New Jersey, Piscataway, NJ 08854, USA.

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March 2012

Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits.

PLoS One 2011 28;6(9):e25416. Epub 2011 Sep 28.

Department of Physiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.

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January 2012

Cognitive decline typical of frontotemporal lobar degeneration in transgenic mice expressing the 25-kDa C-terminal fragment of TDP-43.

Am J Pathol 2012 Jan 7;180(1):293-302. Epub 2011 Nov 7.

Department of Physiology and the Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229-3900, USA.

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January 2012

The role of mTOR signaling in Alzheimer disease.

Authors:
Salvatore Oddo

Front Biosci (Schol Ed) 2012 Jan 1;4:941-52. Epub 2012 Jan 1.

Department of Physiology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229-3900, USA.

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January 2012

Methylene blue reduces aβ levels and rescues early cognitive deficit by increasing proteasome activity.

Brain Pathol 2011 Mar;21(2):140-9

Department of Physiology and The Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229-3900, USA.

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March 2011

Naturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanism.

J Biol Chem 2011 Mar 25;286(11):8924-32. Epub 2011 Jan 25.

Department of Physiology, University of Texas Health Science Center, San Antonio, Texas 78229-3900, USA.

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March 2011

CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease.

Proc Natl Acad Sci U S A 2010 Dec 13;107(52):22687-92. Epub 2010 Dec 13.

Department of Physiology, and Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX 78229, USA.

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December 2010

Age-dependent changes in TDP-43 levels in a mouse model of Alzheimer disease are linked to Aβ oligomers accumulation.

Mol Neurodegener 2010 Nov 11;5:51. Epub 2010 Nov 11.

Department of Physiology and The Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA.

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November 2010

Experience-dependent regulation of vesicular zinc in male and female 3xTg-AD mice.

Neurobiol Aging 2010 Apr 7;31(4):605-13. Epub 2008 Jul 7.

Department of Psychology, University of Calgary, 2500 University Drive, NW, Calgary, Alberta, Canada T2N 1N4.

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April 2010

Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.

J Biol Chem 2010 Apr 23;285(17):13107-20. Epub 2010 Feb 23.

Department of Physiology, University of Texas Health Science Center, San Antonio, Texas 78245, USA.

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April 2010

Rapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability.

J Biol Chem 2009 Oct 3;284(40):27416-24. Epub 2009 Aug 3.

Department of Physiology, University of Texas Health Science Center, San Antonio, Texas 78229, USA.

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October 2009

Genetically altering Abeta distribution from the brain to the vasculature ameliorates tau pathology.

Brain Pathol 2009 Jul 24;19(3):421-30. Epub 2008 Jul 24.

Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697-4545, USA.

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July 2009

Amyloid deposits show complexity and intimate spatial relationship with dendrosomatic plasma membranes: an electron microscopic 3D reconstruction analysis in 3xTg-AD mice and aged canines.

J Alzheimers Dis 2009 ;16(2):315-23

Centre for Molecular Biology and Neuroscience and Department of Anatomy, Institute of Basic Medical Sciences, University of Oslo, Blindern, Oslo, Norway.

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June 2009

Peripherally expressed neprilysin reduces brain amyloid burden: a novel approach for treating Alzheimer's disease.

J Neurosci Res 2009 May;87(6):1462-73

Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, Kentucky 40536-0509, USA.

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May 2009

Reduction of the cerebrovascular volume in a transgenic mouse model of Alzheimer's disease.

Neuropharmacology 2009 Mar;56(4):808-13

Paris-Sud 11 University, EA2706, Faculty of Pharmacy, Châtenay-Malabry, France.

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March 2009

Validation of a 2-day water maze protocol in mice.

Behav Brain Res 2009 Jan 11;196(2):220-7. Epub 2008 Sep 11.

Behavioral Core Facility, Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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January 2009

Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice.

Am J Pathol 2008 Dec 30;173(6):1768-82. Epub 2008 Oct 30.

Department of Microbiology and Immunology, Center for Neural Development and Disease, University of Rochester Medical Center, Rochester, NY 14642, USA.

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December 2008

Increased intraneuronal resting [Ca2+] in adult Alzheimer's disease mice.

J Neurochem 2008 Apr 16;105(1):262-71. Epub 2007 Nov 16.

Department of Anesthesia, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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April 2008

The ubiquitin-proteasome system in Alzheimer's disease.

Authors:
Salvatore Oddo

J Cell Mol Med 2008 Apr 8;12(2):363-73. Epub 2008 Feb 8.

Department of Neurobiology and Behavior University of California, Irvine, CA 92697-4545, USA.

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April 2008

Congo red and thioflavin-T analogs detect Abeta oligomers.

J Neurochem 2008 Jan 22;104(2):457-68. Epub 2007 Oct 22.

M.I.N.D. Institute and Department of Pathology, University of California Davis, Sacramento, California 95817, USA.

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January 2008

Progesterone and estrogen regulate Alzheimer-like neuropathology in female 3xTg-AD mice.

J Neurosci 2007 Nov;27(48):13357-65

Neuroscience Graduate Program, Davis School of Gerontology, University of Southern California, Los Angeles, California 90089, USA.

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November 2007

Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice.

Neurobiol Dis 2007 Oct 23;28(1):76-82. Epub 2007 Jun 23.

Department of Neurobiology and Behavior, 1109 Gillespie Neuroscience Research Facility, University of California, Irvine, Irvine, CA 92697-4545, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756084PMC
October 2007

Neural stem cells improve memory in an inducible mouse model of neuronal loss.

J Neurosci 2007 Oct;27(44):11925-33

Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1627-07.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673368PMC
October 2007

Genetically augmenting tau levels does not modulate the onset or progression of Abeta pathology in transgenic mice.

J Neurochem 2007 Aug 30;102(4):1053-63. Epub 2007 Apr 30.

Department of Neurobiology and Behavior, Institute for Brain Aging and Dementia, University of California, Irvine, California, USA.

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August 2007

Intracellular amyloid-beta in Alzheimer's disease.

Nat Rev Neurosci 2007 Jul;8(7):499-509

Department of Neurobiology and Behaviour, and Institute for Brain Aging and Dementia, University of California, Irvine, California 92697-4545, USA.

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http://dx.doi.org/10.1038/nrn2168DOI Listing
July 2007

Lithium reduces tau phosphorylation but not A beta or working memory deficits in a transgenic model with both plaques and tangles.

Am J Pathol 2007 May;170(5):1669-75

Department of Neurobiology and Behavior, University of California, Irvine, 1109 Gillespie Neuroscience Bldg., Irvine, CA 92697-4545, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1854961PMC
May 2007

Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models.

Ann N Y Acad Sci 2007 Feb;1097:265-77

Department of Neuroscience, Rosalind Franklin University of Medicine and Science, The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, USA.

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http://dx.doi.org/10.1196/annals.1379.025DOI Listing
February 2007

Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles.

J Biol Chem 2006 Dec 20;281(51):39413-23. Epub 2006 Oct 20.

Departments of Neurobiology and Behavior and Neurology, and Institute for Brain Aging and Dementia, University of California, Irvine, California 92697, USA.

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December 2006

Androgens regulate the development of neuropathology in a triple transgenic mouse model of Alzheimer's disease.

J Neurosci 2006 Dec;26(51):13384-9

Neuroscience Graduate Program, University of Southern California, Los Angeles, California 90089, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.2514-06.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6674990PMC
December 2006

The role of nicotinic acetylcholine receptors in Alzheimer's disease.

J Physiol Paris 2006 Mar-May;99(2-3):172-9. Epub 2006 Jan 30.

Department of Neurobiology and Behavior, University of California, Irvine, 1109 Gillespie Neuroscience Building, Irvine, CA 92697-4545, USA.

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http://dx.doi.org/10.1016/j.jphysparis.2005.12.080DOI Listing
June 2006

M1 receptors play a central role in modulating AD-like pathology in transgenic mice.

Neuron 2006 Mar;49(5):671-82

Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697, USA.

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http://dx.doi.org/10.1016/j.neuron.2006.01.020DOI Listing
March 2006

Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology.

J Biol Chem 2006 Jan 10;281(3):1599-604. Epub 2005 Nov 10.

Department of Neurobiology and Behavior, University of California, Irvine, California 92697-4545, USA.

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http://dx.doi.org/10.1074/jbc.M507892200DOI Listing
January 2006

A dynamic relationship between intracellular and extracellular pools of Abeta.

Am J Pathol 2006 Jan;168(1):184-94

Department of Neurobiology and Behavior, University of California, Irvine, 1109 Gillespie Neuroscience Bldg., Irvine, CA 92697-4545, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592652PMC
http://dx.doi.org/10.2353/ajpath.2006.050593DOI Listing
January 2006

Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer's disease.

J Neurochem 2005 Sep;94(6):1711-8

Department of Neurobiology and Behavior, University of California, Irvine, California 92697-4545, USA.

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http://parkerlab.bio.uci.edu/Ian%20S%20Publication/2005_Smit
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http://doi.wiley.com/10.1111/j.1471-4159.2005.03332.x
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http://dx.doi.org/10.1111/j.1471-4159.2005.03332.xDOI Listing
September 2005

Age- and region-dependent alterations in Abeta-degrading enzymes: implications for Abeta-induced disorders.

Neurobiol Aging 2005 May;26(5):645-54

Department of Neurobiology and Behavior, University of California, Irvine, 1109 Gillespie Neuroscience Bldg., Irvine, CA 92697-4545, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S019745800400239
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http://dx.doi.org/10.1016/j.neurobiolaging.2004.06.013DOI Listing
May 2005

Alzheimer's disease: Abeta, tau and synaptic dysfunction.

Trends Mol Med 2005 Apr;11(4):170-6

Department of Neurobiology and Behavior, University of California, Irvine, CA 92697-4545, USA.

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http://dx.doi.org/10.1016/j.molmed.2005.02.009DOI Listing
April 2005

Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice.

Neuron 2005 Mar;45(5):675-88

Department of Neurobiology and Behavior and Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, CA 92697, USA.

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http://dx.doi.org/10.1016/j.neuron.2005.01.040DOI Listing
March 2005

Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease.

Proc Natl Acad Sci U S A 2005 Feb 10;102(8):3046-51. Epub 2005 Feb 10.

Department of Neurobiology and Behavior, University of California, Irvine, CA 92697, USA.

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http://dx.doi.org/10.1073/pnas.0408500102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC549455PMC
February 2005

Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome.

Neuron 2004 Aug;43(3):321-32

Institute for Brain Aging and Dementia, University of California, Irvine, Irvine, CA 92697, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S089662730400424
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http://dx.doi.org/10.1016/j.neuron.2004.07.003DOI Listing
August 2004

Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease.

Neurobiol Aging 2003 Dec;24(8):1063-70

Department of Neurobiology and Behavior, University of California, 1109 Gillespie Neuroscience Research Facility, Irvine, CA 92697-4545, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2003.08.012DOI Listing
December 2003