Sakari Vanharanta

Sakari Vanharanta

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Sakari Vanharanta

Sakari Vanharanta

Publications by authors named "Sakari Vanharanta"

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29Publications

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A KLF6-driven transcriptional network links lipid homeostasis and tumour growth in renal carcinoma.

Nat Commun 2019 03 11;10(1):1152. Epub 2019 Mar 11.

MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Box 197, Cambridge Biomedical Campus, Cambridge, CB2 0XZ, UK.

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http://dx.doi.org/10.1038/s41467-019-09116-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411998PMC
March 2019

Circulating Tumor Cells: Come Together, Right Now, Over Metastasis.

Cancer Discov 2019 01;9(1):22-24

Medical Research Council (MRC) Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge, UK.

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http://dx.doi.org/10.1158/2159-8290.CD-18-1285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420083PMC
January 2019

Endogenous HIF2A reporter systems for high-throughput functional screening.

Sci Rep 2018 08 13;8(1):12063. Epub 2018 Aug 13.

MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Box 197, Biomedical Campus, Cambridge, CB2 0XZ, United Kingdom.

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http://www.nature.com/articles/s41598-018-30499-2
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http://dx.doi.org/10.1038/s41598-018-30499-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089976PMC
August 2018

Epigenetic determinants of metastasis.

Mol Oncol 2017 01 8;11(1):79-96. Epub 2016 Oct 8.

MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge, CB2 0XZ, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2016.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423227PMC
January 2017

Metastatic Competence Can Emerge with Selection of Preexisting Oncogenic Alleles without a Need of New Mutations.

Cancer Res 2015 Sep 24;75(18):3713-9. Epub 2015 Jul 24.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-0562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573898PMC
September 2015

A hypoxic ticket to the bone metastatic niche.

Breast Cancer Res 2015 Sep 4;17:122. Epub 2015 Sep 4.

MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge, CB2 0XZ, UK.

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http://dx.doi.org/10.1186/s13058-015-0635-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558777PMC
September 2015

Therapy-induced tumour secretomes promote resistance and tumour progression.

Nature 2015 Apr 25;520(7547):368-72. Epub 2015 Mar 25.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/nature14336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507807PMC
April 2015

Hypoxia signaling--license to metastasize.

Cancer Discov 2013 Oct;3(10):1103-4

1Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York; and 2Howard Hughes Medical Institute, Chevy Chase, Maryland.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889127PMC
October 2013

Origins of metastatic traits.

Cancer Cell 2013 Oct;24(4):410-21

Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15356108130041
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http://dx.doi.org/10.1016/j.ccr.2013.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998120PMC
October 2013

Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer.

Nat Med 2013 Jan 9;19(1):50-6. Epub 2012 Dec 9.

Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1038/nm.3029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540187PMC
January 2013

Field cancerization: something new under the sun.

Cell 2012 Jun;149(6):1179-81

Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.cell.2012.05.013DOI Listing
June 2012

Stress-induced expression of a novel variant of human fumarate hydratase (FH).

Gene Expr 2007 ;14(2):59-69

Department of Medical Genetics, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042040PMC
March 2008

Allelic imbalance at rs6983267 suggests selection of the risk allele in somatic colorectal tumor evolution.

Cancer Res 2008 Jan;68(1):14-7

Department of Medical Genetics, Genome-Scale Biology Research Program, Biomedicum Helsinki, University of Helsinki, P.O. Box 63, FIN-00014 Helsinki, Finland.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-5766DOI Listing
January 2008

7q deletion mapping and expression profiling in uterine fibroids.

Oncogene 2005 Sep;24(43):6545-54

Department of Medical Genetics, University of Helsinki, PO Box 63 (Haartmaninkatu 8), Biomedicum Helsinki, FIN-00014, Finland.

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http://dx.doi.org/10.1038/sj.onc.1208784DOI Listing
September 2005

Reduced swelling-activated Cl(-) current densities in hypertrophied ventricular myocytes of rabbits with heart failure.

Cardiovasc Res 2002 Mar;53(4):869-78

Department of Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/s0008-6363(01)00507-7DOI Listing
March 2002