Publications by authors named "Sakae Saito"

38Publications

CYP2D6 genotyping analysis and functional characterization of novel allelic variants in a Ni-Vanuatu and Kenyan population by assessing dextromethorphan O-demethylation activity.

Drug Metab Pharmacokinet 2020 Feb 20;35(1):89-101. Epub 2019 Jul 20.

Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan; Advanced Research Center for Innovations in Next-Generation Medicine, Tohoku University, Sendai, 980-8575, Japan; Tohoku Medical Megabank Organization, Tohoku University, Sendai, 980-8575, Japan; Department of Pharmaceutical Sciences, Tohoku University Hospital, Sendai 980-8574, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.dmpk.2019.07.003DOI Listing
February 2020

Impacts of NRF2 activation in non-small-cell lung cancer cell lines on extracellular metabolites.

Cancer Sci 2020 Feb 15;111(2):667-678. Epub 2020 Jan 15.

Department of Integrative Genomics, Tohoku University Tohoku Medical Megabank Organization, Sendai, Japan.

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http://dx.doi.org/10.1111/cas.14278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004536PMC
February 2020

Identification of genetic alterations in extramammary Paget disease using whole exome analysis.

J Dermatol Sci 2019 Apr 11;94(1):229-235. Epub 2019 Apr 11.

Department of Dermatology, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto, 390-8621 Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09231811193007
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http://dx.doi.org/10.1016/j.jdermsci.2019.03.006DOI Listing
April 2019

Development and application of a rapid and sensitive genotyping method for pharmacogene variants using the single-stranded tag hybridization chromatographic printed-array strip (STH-PAS).

Drug Metab Pharmacokinet 2018 Dec 22;33(6):258-263. Epub 2018 Aug 22.

Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba Aramaki, Aoba-ku, Sendai, 980-8578, Japan; Advanced Research Center for Innovations in Next-Generation Medicine, Tohoku University, Sendai, 980-8575, Japan; Tohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, 980-8573, Japan; Department of Pharmaceutical Sciences, Tohoku University Hospital, 1-1 Seiryo-machi, Aoba-ku, Sendai, 980-8574, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.dmpk.2018.08.003DOI Listing
December 2018

Functional characterization of 40 CYP2B6 allelic variants by assessing efavirenz 8-hydroxylation.

Biochem Pharmacol 2018 10 8;156:420-430. Epub 2018 Sep 8.

Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan; Advanced Research Center for Innovations in Next-Generation Medicine, Tohoku University, Sendai 980-8575, Japan; Tohoku Medical Megabank Organization, Tohoku University, Sendai 980-8575, Japan; Department of Pharmaceutical Sciences, Tohoku University Hospital, Sendai 980-8574, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00062952183039
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http://dx.doi.org/10.1016/j.bcp.2018.09.010DOI Listing
October 2018

Functional Characterization of 21 Allelic Variants of Dihydropyrimidine Dehydrogenase Identified in 1070 Japanese Individuals.

Drug Metab Dispos 2018 08 16;46(8):1083-1090. Epub 2018 May 16.

Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences (E.H., Yo.N., F.A., Yu.N., N.H., M.H.), and Tohoku Medical Megabank Organization (S.S., J.Y., M.N., M.Y., M.H.), and Department of Pharmaceutical Sciences, Tohoku University Hospital, Sendai, Japan (M.M., H.Y., N.M., M.H.)

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http://dx.doi.org/10.1124/dmd.118.081737DOI Listing
August 2018

Identification of somatic genetic alterations in ovarian clear cell carcinoma with next generation sequencing.

Genes Chromosomes Cancer 2018 02 30;57(2):51-60. Epub 2017 Oct 30.

Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Miyagi, Japan.

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http://dx.doi.org/10.1002/gcc.22507DOI Listing
February 2018

Use of chemical genomics in assessment of the UPR.

Methods Enzymol 2011 ;491:327-41

Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/B978012385928000
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http://dx.doi.org/10.1016/B978-0-12-385928-0.00018-3DOI Listing
May 2011

Mitochondria regulate the unfolded protein response leading to cancer cell survival under glucose deprivation conditions.

Cancer Sci 2010 May 5;101(5):1125-32. Epub 2010 Feb 5.

The Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan.

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http://doi.wiley.com/10.1111/j.1349-7006.2010.01525.x
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http://dx.doi.org/10.1111/j.1349-7006.2010.01525.xDOI Listing
May 2010

Improvement of hemocompatibility in centrifugal blood pump with hydrodynamic bearings and semi-open impeller: in vitro evaluation.

Artif Organs 2009 Oct 22;33(10):798-804. Epub 2009 Jul 22.

National Institute of Advanced Industrial Science and Technology, Institute for Human Science and Biomedical Engineering, Tsukuba, Ibaraki, Japan.

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http://doi.wiley.com/10.1111/j.1525-1594.2009.00817.x
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http://dx.doi.org/10.1111/j.1525-1594.2009.00817.xDOI Listing
October 2009

A novel endoplasmic reticulum export signal: proline at the +2-position from the signal peptide cleavage site.

J Biol Chem 2009 Oct 5;284(40):27500-10. Epub 2009 Aug 5.

Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M109.021592
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http://dx.doi.org/10.1074/jbc.M109.021592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785679PMC
October 2009

Chemical genomics identifies the unfolded protein response as a target for selective cancer cell killing during glucose deprivation.

Cancer Res 2009 May 12;69(10):4225-34. Epub 2009 May 12.

Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2689DOI Listing
May 2009

Using gene expression profiling to identify a prognostic molecular spectrum in gliomas.

Cancer Sci 2009 Jan 24;100(1):165-72. Epub 2008 Nov 24.

Department of Neurosurgery, Kyoto University Graduate School of Medicine, 54 Kawaharacho, Shogoin Sakyoku, Kyoto, 606-8507, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2008.01002.xDOI Listing
January 2009

Gene expression during the development of experimentally induced cerebral aneurysms.

J Vasc Res 2008 4;45(4):343-9. Epub 2008 Mar 4.

Taisho Laboratory of Functional Genomics, Nara Institute of Science and Technology, Nara, Japan.

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http://dx.doi.org/10.1159/000119200DOI Listing
July 2008

Improvement of hemolysis in a centrifugal blood pump with hydrodynamic bearings and semi-open impeller.

Annu Int Conf IEEE Eng Med Biol Soc 2007 ;2007:3982-5

National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.

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http://dx.doi.org/10.1109/IEMBS.2007.4353206DOI Listing
March 2008

A novel technique for measuring variations in DNA copy-number: competitive genomic polymerase chain reaction.

BMC Genomics 2007 Jul 2;8:206. Epub 2007 Jul 2.

Research Institute, Osaka Medical Center for Cancer and Cardiovascular Diseases, Nakamichi, Higashinari-ku, Osaka, Japan.

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http://dx.doi.org/10.1186/1471-2164-8-206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920520PMC
July 2007

Gene expression profiling of cerebellar development with high-throughput functional analysis.

Physiol Genomics 2005 Jun 29;22(1):8-13. Epub 2005 Mar 29.

Taisho Laboratory of Functional Genomics, Nara Institute of Science and Technology, and Core Research for Evolutional Science and Technology, Japan Science and Technology Corporation, Tokyo, Japan.

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http://dx.doi.org/10.1152/physiolgenomics.00142.2004DOI Listing
June 2005

Adaptor-tagged competitive polymerase chain reaction: amplification bias and quantified gene expression levels.

Anal Biochem 2005 Apr;339(1):15-28

Taisho Laboratory of Functional Genomics, Nara Institute of Science Technology, 8916-5 Takayama, Ikoma, Nara 630-0101, Japan.

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http://dx.doi.org/10.1016/j.ab.2004.11.014DOI Listing
April 2005

Adapter-tagged competitive PCR (ATAC-PCR)--a high-throughput quantitative PCR method for microarray validation.

Methods 2003 Dec;31(4):326-31

Taisho Laboratory of Functional Genomics, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, 630-0101 Nara, Japan.

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http://dx.doi.org/10.1016/s1046-2023(03)00160-9DOI Listing
December 2003

Comparison of gene expression profiling during postnatal development of mouse dentate gyrus and cerebellum.

Physiol Genomics 2002 Feb 28;8(2):131-7. Epub 2002 Feb 28.

Taisho Laboratory of Functional Genomics, Nara Institute of Science and Technology, Ikoma, Nara, 630-0101, Japan.

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http://dx.doi.org/10.1152/physiolgenomics.00077.2001DOI Listing
February 2002