Publications by authors named "Saijun Fan"

100Publications

[Prokaryotic expression, purification and characterization of tissue inhibitor of metalloproteinase-2].

Sheng Wu Gong Cheng Xue Bao 2020 Dec;36(12):2868-2876

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Tianjin 300192, China.

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December 2020

Baicalein ameliorates ionizing radiation-induced injuries by rebalancing gut microbiota and inhibiting apoptosis.

Life Sci 2020 Nov 18;261:118463. Epub 2020 Sep 18.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China. Electronic address:

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November 2020

CLPTM1L induces estrogen receptor β signaling-mediated radioresistance in non-small cell lung cancer cells.

Cell Commun Signal 2020 09 17;18(1):152. Epub 2020 Sep 17.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, 238 Bai-Di Road, Tianjin, 300192, P.R. China.

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September 2020

Sitagliptin Mitigates Total Body Irradiation-Induced Hematopoietic Injury in Mice.

Oxid Med Cell Longev 2020 25;2020:8308616. Epub 2020 Jul 25.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China.

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July 2020

Identification of Key Genes and Pathways Associated With Irradiation in Breast Cancer Tissue and Breast Cancer Cell Lines.

Dose Response 2020 Apr-Jun;18(2):1559325820931252. Epub 2020 Jun 18.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.

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June 2020

Gut Microbiota Metabolite Fights Against Dietary Polysorbate 80-Aggravated Radiation Enteritis.

Front Microbiol 2020 26;11:1450. Epub 2020 Jun 26.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.

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June 2020

Enhanced radiotherapy using photothermal therapy based on dual-sensitizer of gold nanoparticles with acid-induced aggregation.

Nanomedicine 2020 10 18;29:102241. Epub 2020 Jun 18.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Nankai District, Tianjin, PR China. Electronic address:

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October 2020

Hyaluronic Acid-Modified Au-Ag Alloy Nanoparticles for Radiation/Nanozyme/Ag Multimodal Synergistically Enhanced Cancer Therapy.

Bioconjug Chem 2020 07 11;31(7):1756-1765. Epub 2020 Jun 11.

CAS Key Laboratory of Nano-Bio Interface, Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123, China.

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July 2020

LncRNA HOTAIR enhances breast cancer radioresistance through facilitating HSPA1A expression via sequestering miR-449b-5p.

Thorac Cancer 2020 07 6;11(7):1801-1816. Epub 2020 May 6.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.

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July 2020

HJC0152 suppresses human non-small-cell lung cancer by inhibiting STAT3 and modulating metabolism.

Cell Prolif 2020 Mar 5;53(3):e12777. Epub 2020 Feb 5.

Department of Genetics, Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, Louisiana Cancer Research Center, New Orleans, LA, USA.

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March 2020

Gut commensal derived-valeric acid protects against radiation injuries.

Gut Microbes 2020 07 13;11(4):789-806. Epub 2020 Jan 13.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College , Tianjin, China.

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July 2020

Sexual Dimorphism of Gut Microbiota Dictates Therapeutics Efficacy of Radiation Injuries.

Adv Sci (Weinh) 2019 Nov 29;6(21):1901048. Epub 2019 Aug 29.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine Institute of Radiation Medicine Chinese Academy of Medical Sciences and Peking Union Medical College 238 Baidi Road Tianjin 300192 China.

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November 2019

Protective effects of zingerone derivate on ionizing radiation-induced intestinal injury.

J Radiat Res 2019 Nov;60(6):740-746

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300192, China.

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November 2019

Total body irradiation induced mouse small intestine senescence as a late effect.

J Radiat Res 2019 Jul;60(4):442-450

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin, China.

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July 2019

MiR-365 enhances the radiosensitivity of non-small cell lung cancer cells through targeting CDC25A.

Biochem Biophys Res Commun 2019 04 20;512(2):392-398. Epub 2019 Mar 20.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, PR China. Electronic address:

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April 2019

Enzyme-instructed self-assembly of a novel histone deacetylase inhibitor with enhanced selectivity and anticancer efficiency.

Biomater Sci 2019 Mar;7(4):1477-1485

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China.

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March 2019

Mouse serum protects against total body irradiation-induced hematopoietic system injury by improving the systemic environment after radiation.

Free Radic Biol Med 2019 02 19;131:382-392. Epub 2018 Dec 19.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science/Peking Union Medical College, Tianjin 300192, China. Electronic address:

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February 2019

Cordycepin sensitizes breast cancer cells toward irradiation through elevating ROS production involving Nrf2.

Toxicol Appl Pharmacol 2019 02 7;364:12-21. Epub 2018 Dec 7.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China. Electronic address:

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February 2019

Amelioration of whole abdominal irradiation-induced intestinal injury in mice with 3,3'-Diindolylmethane (DIM).

Free Radic Biol Med 2019 01 21;130:244-255. Epub 2018 Oct 21.

Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Tianjin 300192, China. Electronic address:

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January 2019

Activation of STAT3 and Bcl-2 and reduction of reactive oxygen species (ROS) promote radioresistance in breast cancer and overcome of radioresistance with niclosamide.

Oncogene 2018 09 31;37(39):5292-5304. Epub 2018 May 31.

Department of Clinical Cancer Prevention, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.

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September 2018

Low dose irradiation facilitates hepatocellular carcinoma genesis involving HULC.

Mol Carcinog 2018 07 6;57(7):926-935. Epub 2018 Apr 6.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.

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July 2018

hsa-miR-212 modulates the radiosensitivity of glioma cells by targeting BRCA1.

Authors:
Xin He Saijun Fan

Oncol Rep 2018 Mar 15;39(3):977-984. Epub 2017 Dec 15.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Sciences, Tianjin 300192, P.R. China.

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March 2018

Theaflavin ameliorates ionizing radiation-induced hematopoietic injury via the NRF2 pathway.

Free Radic Biol Med 2017 12 20;113:59-70. Epub 2017 Sep 20.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin 300192, China. Electronic address:

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December 2017

Total abdominal irradiation exposure impairs cognitive function involving miR-34a-5p/BDNF axis.

Biochim Biophys Acta Mol Basis Dis 2017 09 29;1863(9):2333-2341. Epub 2017 Jun 29.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, 238 Baidi Road, Tianjin 300192, China. Electronic address:

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September 2017

Rutin-Enriched Extract from Coriandrum sativum L. Ameliorates Ionizing Radiation-Induced Hematopoietic Injury.

Int J Mol Sci 2017 Apr 29;18(5). Epub 2017 Apr 29.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin 300192, China.

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April 2017

Polydatin down-regulates the phosphorylation level of Creb and induces apoptosis in human breast cancer cell.

PLoS One 2017 3;12(5):e0176501. Epub 2017 May 3.

Department of Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, P.R. China.

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September 2017

Hydrogen-Rich Water Ameliorates Total Body Irradiation-Induced Hematopoietic Stem Cell Injury by Reducing Hydroxyl Radical.

Oxid Med Cell Longev 2017 22;2017:8241678. Epub 2017 Jan 22.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin 300192, China.

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March 2017

Faecal microbiota transplantation protects against radiation-induced toxicity.

EMBO Mol Med 2017 04;9(4):448-461

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China

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April 2017

The development and biological characteristics of a novel potentially radioresistant inbred mouse strain.

Mol Med Rep 2017 Feb 22;15(2):759-767. Epub 2016 Dec 22.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine of Chinese Academy of Medical Science, Tianjin 300192, P.R. China.

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February 2017

Vam3 ameliorates total body irradiation-induced hematopoietic system injury partly by regulating the expression of Nrf2-targeted genes.

Free Radic Biol Med 2016 12 27;101:455-464. Epub 2016 Oct 27.

Tianjin Key Lab of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin 300192, China. Electronic address:

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December 2016

Design and Synthesis of Vandetanib Derivatives Containing Nitroimidazole Groups as Tyrosine Kinase Inhibitors in Normoxia and Hypoxia.

Molecules 2016 Dec 14;21(12). Epub 2016 Dec 14.

Chongqing Technical Center for Drug Evaluation & Certification, Chongqing 400014, China.

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December 2016

B7-H3 regulates lipid metabolism of lung cancer through SREBP1-mediated expression of FASN.

Biochem Biophys Res Commun 2017 Jan 7;482(4):1246-1251. Epub 2016 Dec 7.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, 238 Baidi Road, Tianjin, 300192, PR China. Electronic address:

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January 2017

Circadian Rhythm Shapes the Gut Microbiota Affecting Host Radiosensitivity.

Int J Mol Sci 2016 Oct 26;17(11). Epub 2016 Oct 26.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, 238 Baidi Road, Tianjin 300192, China.

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October 2016

3,3'-diindolylmethane mitigates total body irradiation-induced hematopoietic injury in mice.

Free Radic Biol Med 2016 10 5;99:463-471. Epub 2016 Sep 5.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China. Electronic address:

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October 2016

Ionizing Radiation Induces HMGB1 Cytoplasmic Translocation and Extracellular Release.

Guo Ji Fang She Yi Xue He Yi Xue Za Zhi 2016 Mar 15;40(2):91-99. Epub 2016 Apr 15.

School of Radiation and Public Health, Soochow University Medical College, Suzhou, Jiangsu 215123, China; Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China; Laboratory of Emergency Medicine, Feinstein Institute for Medical Research, Manhasset, NY 11030, USA.

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March 2016

Retraction Note: Changes in the electron paramagnetic resonance spectra of albumin-associated spin-labeled stearic acid as a diagnostic parameter of colorectal cancer.

World J Surg Oncol 2016 06 2;14(1):156. Epub 2016 Jun 2.

Department of Radiation Protection Center, Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin Key Laboratory of Molecular Nuclear Medicine, 238 Baidi Road, Nankai District, Tianjin, 300192, People's Republic of China.

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June 2016

Solid cancer incidence among Chinese medical diagnostic x-ray workers, 1950-1995: Estimation of radiation-related risks.

Int J Cancer 2016 Jun 25;138(12):2875-83. Epub 2016 Mar 25.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.

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June 2016

Accumulation and Phosphorylation of RecQ-Mediated Genome Instability Protein 1 (RMI1) at Serine 284 and Serine 292 during Mitosis.

Int J Mol Sci 2015 Nov 4;16(11):26395-405. Epub 2015 Nov 4.

Department of Experimental Radiation Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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November 2015

Exploration of peptide T7 and its derivative as integrin αvβ3-targeted imaging agents.

Onco Targets Ther 2015 15;8:1483-91. Epub 2015 Jun 15.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Sciences, Tianjin, People's Republic of China.

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June 2015

Use of epidermal growth factor receptor antibody-gold cluster conjugates with good renal excretion in targeted cancer radiation treatment.

J Mater Chem B 2015 Jun 26;3(23):4735-4741. Epub 2015 May 26.

Tianjin Key Laboratory of Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 238, Baidi Road, Tianjin 300192, China.

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June 2015

Novel Mechanisms of Herbal Therapies for Inhibiting HMGB1 Secretion or Action.

Evid Based Complement Alternat Med 2015 2;2015:456305. Epub 2015 Mar 2.

Department of Emergency Medicine, North Shore University Hospital, Manhasset, NY 11030, USA ; The Feinstein Institute for Medical Research, North Shore-LIJ Health System, 350 Community Drive, Manhasset, NY 11030, USA.

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March 2015

N-acetylcysteine relieves oxidative stress and protects hippocampus of rat from radiation-induced apoptosis by inhibiting caspase-3.

Biomed Pharmacother 2015 Mar 24;70:1-6. Epub 2014 Dec 24.

Tianjin Key Lab of Molecular Nuclear Medicine, Institute of Radiation Medicine of Chinese Academy of Medical Science and Peking Union Medical College, Tianjin, PR China. Electronic address:

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March 2015

Ultrasmall glutathione-protected gold nanoclusters as next generation radiotherapy sensitizers with high tumor uptake and high renal clearance.

Sci Rep 2015 Mar 2;5:8669. Epub 2015 Mar 2.

Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117585, Singapore.

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March 2015

Dynamic biostability, biodistribution, and toxicity of L/D-peptide-based supramolecular nanofibers.

ACS Appl Mater Interfaces 2015 Feb 20;7(4):2735-44. Epub 2015 Jan 20.

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science & Peking Union Medical College , Tianjin 300192, P. R. China.

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February 2015

Storage of gold nanoclusters in muscle leads to their biphasic in vivo clearance.

Small 2015 Apr 18;11(14):1683-90. Epub 2014 Nov 18.

Tianjin Key Laboratory of Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China.

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April 2015

Different effects of LDH-A inhibition by oxamate in non-small cell lung cancer cells.

Oncotarget 2014 Dec;5(23):11886-96

Department of Radiation Therapy, Zhejiang Cancer Hospital, Hangzhou, China. Zhejiang Key Laboratory of Radiation Oncology, Hangzhou, China.

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December 2014

The study of external dose rate and retained body activity of patients receiving 131I therapy for differentiated thyroid carcinoma.

Int J Environ Res Public Health 2014 Oct 21;11(10):10991-1003. Epub 2014 Oct 21.

Tianjin Key Laboratory of Molecular Nuclear Medicine, Institute Of Radiation Medicine, Chinese Academy Of Medical Sciences & Peking Union Medical College, Tianjin 300192, China.

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October 2014

A combined experimental and computational study of Vam3, a derivative of resveratrol, and Syk interaction.

Int J Mol Sci 2014 Sep 25;15(9):17188-203. Epub 2014 Sep 25.

Key Lab of Tianjin Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, Tianjin 300192, China.

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September 2014

Estimating radiation absorbed dose of individuals nearby 131I-treated hyperthyroid patients.

Health Phys 2014 Mar;106(3):365-9

*Institute of Radiation Medicine, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin 300192, P.R. China; †Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, P.R. China.

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March 2014

Mitigating the effects of Xuebijing injection on hematopoietic cell injury induced by total body irradiation with γ rays by decreasing reactive oxygen species levels.

Int J Mol Sci 2014 Jun 12;15(6):10541-53. Epub 2014 Jun 12.

Tianjin Key Lab of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Academy of Medical Science and Peking Union Medical College, Tianjin 300192, China.

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June 2014

Mixture of nonionic/ionic surfactants for the formulation of nanostructured lipid carriers: effects on physical properties.

Langmuir 2014 Jun 29;30(23):6920-8. Epub 2014 May 29.

Shanghai Key Laboratory of Functional Materials Chemistry, State Key Laboratory of Bioreactor Engineering and Institute of Applied Chemistry, East China University of Science and Technology , Shanghai 200237, P. R. China.

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June 2014

Ultrasmall Au(10-12)(SG)(10-12) nanomolecules for high tumor specificity and cancer radiotherapy.

Adv Mater 2014 Jul 11;26(26):4565-8. Epub 2014 May 11.

Tianjin Key Laboratory of Molecular Nuclear Medicine, Institute of Radiation Medicine Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China.

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July 2014

Passing through the renal clearance barrier: toward ultrasmall sizes with stable ligands for potential clinical applications.

Int J Nanomedicine 2014 25;9:2069-72. Epub 2014 Apr 25.

Tianjin Key Laboratory of Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, People's Republic of China.

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December 2014

Polysaccharide isolated from Parmelia tinctorum ameliorates ionizing irradiation-induced damage in mice.

J Radiat Res 2014 Jul 9;55(4):641-7. Epub 2014 Apr 9.

Tianjin Key Laboratory of Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China.

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July 2014

Radioprotective and antioxidant effect of resveratrol in hippocampus by activating Sirt1.

Int J Mol Sci 2014 Apr 9;15(4):5928-39. Epub 2014 Apr 9.

Tianjin Key Lab of Molecular Nuclear Medicine, Institute of Radiation Medicine of Chinese Academy of Medical Science and Peking Union Medical College, Tianjin 300192, China.

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April 2014

The in vitro and in vivo toxicity of graphene quantum dots.

Biomaterials 2014 Jun 28;35(19):5041-8. Epub 2014 Mar 28.

Suzhou Key Laboratory of Nanobiomedicine, Division of Nanobiomedicine & Collaborative Innovation Center of Suzhou Nano Science and Technology, Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences, 398 Ruoshui Road, Suzhou 215123, China. Electronic address:

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June 2014

Thoc1 inhibits cell growth via induction of cell cycle arrest and apoptosis in lung cancer cells.

Mol Med Rep 2014 Jun 28;9(6):2321-7. Epub 2014 Mar 28.

School of Radiation Medicine and Protection, Medical College, Soochow University, Suzhou, Jiangsu 215123, P.R. China.

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June 2014

Sanguinarine is a novel VEGF inhibitor involved in the suppression of angiogenesis and cell migration.

Mol Clin Oncol 2013 Mar 20;1(2):331-336. Epub 2012 Nov 20.

School of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou, Jiangsu 215123, P.R. China ;

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March 2013

shRNA-mediated XRCC2 gene knockdown efficiently sensitizes colon tumor cells to X-ray irradiation in vitro and in vivo.

Int J Mol Sci 2014 Jan 29;15(2):2157-71. Epub 2014 Jan 29.

Tianjin Key Lab of Molecular Nuclear Medicine, Institute of Radiation Medicine of Chinese, Academy of Medical Science and Peking Union Medical College, Tianjin 300192, China.

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January 2014

Polydatin inhibits growth of lung cancer cells by inducing apoptosis and causing cell cycle arrest.

Oncol Lett 2014 Jan 21;7(1):295-301. Epub 2013 Nov 21.

School of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou, Jiangsu 215123, P.R. China.

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January 2014

The impact of PEGylation patterns on the in vivo biodistribution of mixed shell micelles.

Int J Nanomedicine 2013 5;8:4229-46. Epub 2013 Nov 5.

Key Laboratory of Functional Polymer Materials, Ministry of Education, and Institute of Polymer Chemistry, Nankai University, Tianjin, People's Republic of China.

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June 2014

DIM (3,3'-diindolylmethane) confers protection against ionizing radiation by a unique mechanism.

Proc Natl Acad Sci U S A 2013 Nov 14;110(46):18650-5. Epub 2013 Oct 14.

Departments of Oncology, Radiation Medicine, and Biochemistry and Molecular and Cell Biology, Georgetown University Medical Center, Washington, DC 20057.

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November 2013

Changes in the electron paramagnetic resonance spectra of albumin-associated spin-labeled stearic acid as a diagnostic parameter of colorectal cancer.

World J Surg Oncol 2013 Sep 11;11:223. Epub 2013 Sep 11.

Department of Radiation Protection Center, Institute of Radiation Medicine, Chinese Academy of Medical Sciences&Peking Union Medical College, Tianjin Key Laboratory of Molecular Nuclear Medicine, 238 Baidi Road, Nankai District, Tianjin 300192, P,R, China.

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September 2013

Green tea catechins quench the fluorescence of bacteria-conjugated Alexa fluor dyes.

Inflamm Allergy Drug Targets 2013 Oct;12(5):308-14

Department of Emergency Medicine, North Shore University Hospital, 350 Community Drive, Manhasset, NY 11030, USA.

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October 2013

Resveratrol inhibits ionising irradiation-induced inflammation in MSCs by activating SIRT1 and limiting NLRP-3 inflammasome activation.

Int J Mol Sci 2013 Jul 8;14(7):14105-18. Epub 2013 Jul 8.

Tianjin Key Lab of Molecular Nuclear Medicine, Institute of Radiation Medicine of Chinese Academy of Medical Science and Peking Union Medical College, Tianjin 300192, China.

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July 2013

Enhanced tumor accumulation of sub-2 nm gold nanoclusters for cancer radiation therapy.

Adv Healthc Mater 2014 Jan 22;3(1):133-41. Epub 2013 Jul 22.

Tianjin Key Laboratory of Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China.

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January 2014

Sex differences in the toxicity of polyethylene glycol-coated gold nanoparticles in mice.

Int J Nanomedicine 2013 4;8:2409-19. Epub 2013 Jul 4.

Tianjin Key Laboratory of Molecular Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Nankai District, Tianjin, People's Republic of China.

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April 2014

Inhibitory impacts of chemically modified tetracycline-3 and underlying mechanism in human cervical cancer cells.

Anticancer Drugs 2013 Sep;24(8):799-809

School of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou, People's Republic of China.

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September 2013

The effects of p38 MAPK inhibition combined with G-CSF administration on the hematoimmune system in mice with irradiation injury.

PLoS One 2013 30;8(4):e62921. Epub 2013 Apr 30.

Institute of Radiation Medicine, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin Key Laboratory of Molecular Nuclear Medicine, Tianjin, China.

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November 2013

Preparation and characterization of 4-dedimethylamino sancycline (CMT-3) loaded nanostructured lipid carrier (CMT-3/NLC) formulations.

Int J Pharm 2013 Jun 20;450(1-2):225-34. Epub 2013 Apr 20.

State Key Laboratory of Bioreactor Engineering and Institute of Applied Chemistry, East China University of Science and Technology, Shanghai 200237, PR China.

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June 2013

Tanshinone IIA sodium sulfonate facilitates endocytic HMGB1 uptake.

Biochem Pharmacol 2012 Dec 26;84(11):1492-500. Epub 2012 Sep 26.

The Feinstein Institute for Medical Research, Manhasset, NY 11030, USA.

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December 2012

Sanguinarine inhibits growth of human cervical cancer cells through the induction of apoptosis.

Oncol Rep 2012 Dec 11;28(6):2264-70. Epub 2012 Sep 11.

School of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou, Jiangsu 215123, PR China.

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December 2012

[BRCA1: a new predictive genomic marker for chemotherapy and radiotherapy of non-small cell lung cancer].

Authors:
Min Li Saijun Fan

Zhongguo Fei Ai Za Zhi 2012 Aug;15(8):481-90

School of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou 215123, China.

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August 2012

RNA interference against SPARC promotes the growth of U-87MG human malignant glioma cells.

Oncol Lett 2011 Sep 5;2(5):985-990. Epub 2011 Jul 5.

Department of Radiobiology, School of Radiation Medicine and Public Health, Soochow University, Suzhou 215123, P.R. China.

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September 2011

[EGFR-dependent impact of indol-3-carbinol on radiosensitivity of lung cancer cells].

Zhongguo Fei Ai Za Zhi 2012 Jul;15(7):391-8

School of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou, China.

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July 2012

Hypoxia-inducible factor-1α downregulation by small interfering RNA inhibits proliferation, induces apoptosis, and enhances radiosensitivity in chemical hypoxic human hepatoma SMMC-7721 cells.

Cancer Biother Radiopharm 2011 Oct 27;26(5):565-71. Epub 2011 Sep 27.

Department of Radiobiology, School of Radiological Medicine and Public Health, Soochow University, No. 199 Renai Road, Suzhou, China.

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October 2011

EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages.

Biochem Pharmacol 2011 May 1;81(9):1152-63. Epub 2011 Mar 1.

The Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, NY 11030, USA.

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May 2011

BTG2 is an LXXLL-dependent co-repressor for androgen receptor transcriptional activity.

Biochem Biophys Res Commun 2011 Jan 21;404(4):903-9. Epub 2010 Dec 21.

School of Radiation Medicine and Public Health, Medical College of Soochow University, Suzhou 215123, China.

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January 2011

UHRF1 confers radioresistance to human breast cancer cells.

Int J Radiat Biol 2011 Mar 10;87(3):263-73. Epub 2010 Nov 10.

School of Radiation Medicine and Public Health, Medical College of Soochow University, Suzhou, Jiangsu, P. R. China.

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March 2011

[Advances in Anti-tumor Activity of Indole-3-carbinol.].

Authors:
Chang Ge Saijun Fan

Zhongguo Fei Ai Za Zhi 2009 Sep;12(9):1044-6

School of Radiation and Public Health, Soochow University, Suzhou 215123, China.

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September 2009

BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.

Mol Endocrinol 2010 Jan 3;24(1):76-90. Epub 2009 Nov 3.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057-1469, USA.

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January 2010

Scatter factor protects tumor cells against apoptosis caused by TRAIL.

Anticancer Drugs 2010 Jan;21(1):10-24

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057-1469, USA.

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January 2010

BRCA1 localization to the telomere and its loss from the telomere in response to DNA damage.

J Biol Chem 2009 Dec 21;284(52):36083-98. Epub 2009 Sep 21.

Department of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC 20057, USA.

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December 2009

ATM-dependent hyper-radiosensitivity in mammalian cells irradiated by heavy ions.

Int J Radiat Oncol Biol Phys 2009 Sep;75(1):235-43

School of Radiation Medicine and Public Health, Medical College of Soochow University, Suzhou, China.

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September 2009

Low concentrations of diindolylmethane, a metabolite of indole-3-carbinol, protect against oxidative stress in a BRCA1-dependent manner.

Cancer Res 2009 Aug 21;69(15):6083-91. Epub 2009 Jul 21.

Department of Oncology, Georgetown University, Washington, District of Columbia200 57, USA.

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August 2009

Regulation of ATM in DNA double strand break repair accounts for the radiosensitivity in human cells exposed to high linear energy transfer ionizing radiation.

Mutat Res 2009 Nov 5;670(1-2):15-23. Epub 2009 Jul 5.

School of Radiation Medicine and Public Health, Medical College of Soochow University, Suzhou, China.

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November 2009

Mechanism of BRCA1-mediated inhibition of progesterone receptor transcriptional activity.

Mol Endocrinol 2009 Aug 23;23(8):1135-46. Epub 2009 Apr 23.

Department of Oncology, Lombardi Comprehensive Cancer Center/Georgetown University, Washington, D.C. 20057-1469, USA.

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August 2009

BRCA1 Cross-Talk with Hormone Receptors.

Cancer Treat Res 2009 ;147:1-20

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Box 571469, 3970 Reservoir Road, NW, Washington, DC 20057-1469, USA,

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April 2016

Role of Src signal transduction pathways in scatter factor-mediated cellular protection.

J Biol Chem 2009 Mar 1;284(12):7561-77. Epub 2008 Dec 1.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA.

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March 2009

Growth factor signaling pathways modulate BRCA1 repression of estrogen receptor-alpha activity.

Mol Endocrinol 2007 Aug 15;21(8):1905-23. Epub 2007 May 15.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, D.C. 20057-1469, USA.

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August 2007

Identification of genes that modulate sensitivity of U373MG glioblastoma cells to cis-platinum.

Anticancer Drugs 2006 Aug;17(7):733-51

Department of Oncology, Lombardi Comprehensive Cancer Center/Georgetown University, Washington, District of Columbia 20057-1469, USA.

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August 2006

Regulation of progesterone receptor signaling by BRCA1 in mammary cancer.

Nucl Recept Signal 2006 28;4:e006. Epub 2006 Apr 28.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA.

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July 2006

Scatter factor mitigates HIV-1 gp120-induced human mesangial cell injury.

Nephron Exp Nephrol 2006 22;103(3):e103-8. Epub 2006 Mar 22.

Department of Medicine, Long Island Jewish Medical Center (LIJMC), New Hyde Park, NY, USA.

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August 2006

BRCA1 regulates gene expression for orderly mitotic progression.

Cell Cycle 2005 Nov 7;4(11):1641-66. Epub 2005 Nov 7.

Department of Oncology, Lombardi Cancer Center, Georgetown University, Washington, DC 20057-1469, USA.

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November 2005

p300 modulates HIV-1 gp120-induced apoptosis in human proximal tubular cells: associated with alteration of TGF-beta and Smad signaling.

Nephron Exp Nephrol 2006 20;102(1):e30-8. Epub 2005 Sep 20.

Division of Nephrology, Department of Medicine, Long Island Jewish Medical Center, The Long Island Campus, Albert Einstein College of Medicine, New Hyde Park, NY, USA.

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April 2006

The breast cancer susceptibility gene BRCA1 regulates progesterone receptor signaling in mammary epithelial cells.

Mol Endocrinol 2006 Jan 18;20(1):14-34. Epub 2005 Aug 18.

Department of Oncology, Lombardi Cancer Center, Georgetown University, Washington, DC 20057-1469, USA.

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January 2006

Cyclin D1 antagonizes BRCA1 repression of estrogen receptor alpha activity.

Cancer Res 2005 Aug;65(15):6557-67

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University School of Medicine, Washington, District of Columbia 20007, USA.

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August 2005