Sagiv Shifman

Sagiv Shifman

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Sagiv Shifman

Sagiv Shifman

Publications by authors named "Sagiv Shifman"

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Genes essential for embryonic stem cells are associated with neurodevelopmental disorders.

Genome Res 2019 11 24;29(11):1910-1918. Epub 2019 Oct 24.

Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel.

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http://dx.doi.org/10.1101/gr.250019.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836742PMC
November 2019

Gene network analysis reveals a role for striatal glutamatergic receptors in dysregulated risk-assessment behavior of autism mouse models.

Transl Psychiatry 2019 Oct 17;9(1):257. Epub 2019 Oct 17.

Molecular and Behavioral Neurosciences Lab, Bar-Ilan University Faculty of Medicine, 1311502, Safed, Israel.

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http://dx.doi.org/10.1038/s41398-019-0584-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797764PMC
October 2019

Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI.

Nat Commun 2019 07 30;10(1):3403. Epub 2019 Jul 30.

The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, Jerusalem, 9190401, Israel.

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http://dx.doi.org/10.1038/s41467-019-11319-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667463PMC
July 2019

AUTS2 isoforms control neuronal differentiation.

Mol Psychiatry 2019 Apr 5. Epub 2019 Apr 5.

Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.

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http://dx.doi.org/10.1038/s41380-019-0409-1DOI Listing
April 2019

Widespread Allelic Heterogeneity in Complex Traits.

Am J Hum Genet 2017 May;100(5):789-802

Department of Computer Science, University of California, Los Angeles, CA 90095, USA; Department of Human Genetics, University of California, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420356PMC
May 2017

Varying Intolerance of Gene Pathways to Mutational Classes Explain Genetic Convergence across Neuropsychiatric Disorders.

Cell Rep 2017 02;18(9):2217-2227

Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247173017
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http://dx.doi.org/10.1016/j.celrep.2017.02.007DOI Listing
February 2017

Transcriptional dynamics in colorectal carcinogenesis: new insights into the role of c-Myc and miR17 in benign to cancer transformation.

Cancer Res 2014 Oct 14;74(19):5532-40. Epub 2014 Aug 14.

Department of Genetics, The Life Sciences Institute, Edmond J. Safra Campus, The Hebrew University, Jerusalem, Israel.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-0932DOI Listing
October 2014

Competing targets of microRNA-608 affect anxiety and hypertension.

Hum Mol Genet 2014 Sep 9;23(17):4569-80. Epub 2014 Apr 9.

The Silberman Institute of Life Sciences and The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, The Edmond Safra Campus, Givat Ram, Jerusalem 91904, Israel

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http://dx.doi.org/10.1093/hmg/ddu170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119407PMC
September 2014

Allelic expression analysis in the brain suggests a role for heterogeneous insults affecting epigenetic processes in autism spectrum disorders.

Hum Mol Genet 2014 Aug 21;23(15):4111-24. Epub 2014 Mar 21.

Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddu128DOI Listing
August 2014

Bias towards large genes in autism.

Nature 2014 Aug;512(7512):E1-2

Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.

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http://dx.doi.org/10.1038/nature13583DOI Listing
August 2014

Global coevolution of human microRNAs and their target genes.

Mol Biol Evol 2014 May 4;31(5):1237-47. Epub 2014 Mar 4.

Department of Biological Chemistry, The Institute of Life Sciences and The Edmond & Lily Safra Center for Brain Sciences, Hebrew University of Jerusalem, Jerusalem, Israel.

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http://dx.doi.org/10.1093/molbev/msu090DOI Listing
May 2014

Chromatin regulators, phenotypic robustness, and autism risk.

Front Genet 2014 10;5:81. Epub 2014 Apr 10.

Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem Jerusalem, Israel.

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http://dx.doi.org/10.3389/fgene.2014.00081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989700PMC
April 2014

Networks of neuronal genes affected by common and rare variants in autism spectrum disorders.

PLoS Genet 2012 8;8(3):e1002556. Epub 2012 Mar 8.

Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.

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https://dx.plos.org/10.1371/journal.pgen.1002556
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http://dx.doi.org/10.1371/journal.pgen.1002556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297570PMC
September 2012

Neurogenomic evidence for a shared mechanism of the antidepressant effects of exercise and chronic fluoxetine in mice.

PLoS One 2012 25;7(4):e35901. Epub 2012 Apr 25.

Department and Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035901PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338479PMC
September 2012

The genetic variation of RELN expression in schizophrenia and bipolar disorder.

PLoS One 2011 16;6(5):e19955. Epub 2011 May 16.

Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019955PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095646PMC
October 2011

Identification of a functional rare variant in autism using genome-wide screen for monoallelic expression.

Hum Mol Genet 2011 Sep 16;20(18):3632-41. Epub 2011 Jun 16.

Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem,Edmond J. Safra campus, Jerusalem 91904, Israel.

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http://dx.doi.org/10.1093/hmg/ddr283DOI Listing
September 2011

Further investigation of the association between rs7341475 and rs17746501 and schizophrenia.

Am J Med Genet B Neuropsychiatr Genet 2010 Sep;153B(6):1244-7

Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.

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http://doi.wiley.com/10.1002/ajmg.b.31093
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http://dx.doi.org/10.1002/ajmg.b.31093DOI Listing
September 2010

Human embryonic stem cells from aneuploid blastocysts identified by pre-implantation genetic screening.

In Vitro Cell Dev Biol Anim 2010 Apr 12;46(3-4):309-16. Epub 2010 Mar 12.

The International Stem Cell Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

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http://link.springer.com/10.1007/s11626-010-9303-5
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http://dx.doi.org/10.1007/s11626-010-9303-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855810PMC
April 2010

Genetic variants in major depression.

Novartis Found Symp 2008 ;289:23-32; discussion 33-42, 87-93

Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1002/9780470751251.ch3DOI Listing
August 2008

Animal models of psychiatric disease.

Curr Opin Genet Dev 2008 Jun 11;18(3):235-40. Epub 2008 Aug 11.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S0959437X0800080
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http://dx.doi.org/10.1016/j.gde.2008.07.002DOI Listing
June 2008

Strategies for mapping and cloning quantitative trait genes in rodents.

Nat Rev Genet 2005 Apr;6(4):271-86

Wellcome Trust Centre for Human Genetics, Oxford University, Roosevelt Drive, Oxford OX3 7BN, United Kingdom.

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http://dx.doi.org/10.1038/nrg1576DOI Listing
April 2005

A survey of the 22q11 microdeletion in a large cohort of schizophrenia patients.

Schizophr Res 2005 Mar;73(2-3):263-7

The Life Science Institute, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.

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http://dx.doi.org/10.1016/j.schres.2004.02.008DOI Listing
March 2005

Mouse inbred strain sequence information and yin-yang crosses for quantitative trait locus fine mapping.

Genetics 2005 Feb 1;169(2):849-54. Epub 2004 Nov 1.

The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.

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http://dx.doi.org/10.1534/genetics.104.032474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1449093PMC
February 2005

The beauty of admixture.

Nat Genet 2005 Feb;37(2):118-9

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http://dx.doi.org/10.1038/ng0205-118DOI Listing
February 2005

Linkage disequilibrium patterns of the human genome across populations.

Hum Mol Genet 2003 Apr;12(7):771-6

The Life Sciences Institute, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.

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http://dx.doi.org/10.1093/hmg/ddg088DOI Listing
April 2003

Quantitative technologies for allele frequency estimation of SNPs in DNA pools.

Mol Cell Probes 2002 Dec;16(6):429-34

Department of Evolution, Systematics and Ecology, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.

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http://dx.doi.org/10.1006/mcpr.2002.0440DOI Listing
December 2002

Genetic dissection of common diseases.

Isr Med Assoc J 2002 Jun;4(6):438-43

IDgene Pharmaceutical Ltd. Jerusalem, Israel.

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June 2002

Power and efficiency of the TDT and case-control design for association scans.

Behav Genet 2002 Mar;32(2):135-44

GlaxoSmithKline Pharmaceuticals, Harlow, Essex, United Kingdom.

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http://dx.doi.org/10.1023/a:1015205924326DOI Listing
March 2002

Population-based gene discovery in the post-genomic era.

Drug Discov Today 2001 Nov;6(21):1111-1115

IDgene Pharmaceuticals, PO Box 34478, 91344, Jerusalem, Israel

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http://dx.doi.org/10.1016/s1359-6446(01)02007-4DOI Listing
November 2001