Publications by authors named "Sachie Marubayashi"

10Publications

Tumors establish resistance to immunotherapy by regulating T recruitment via CCR4.

Authors:
Lisa A Marshall Sachie Marubayashi Aparna Jorapur Scott Jacobson Mikhail Zibinsky Omar Robles Dennis Xiaozhou Hu Jeffrey J Jackson Deepa Pookot Jerick Sanchez Martin Brovarney Angela Wadsworth David Chian David Wustrow Paul D Kassner Gene Cutler Brian Wong Dirk G Brockstedt Oezcan Talay

J Immunother Cancer 2020 Nov;8(2)

RAPT Therapeutics, South San Francisco, California, USA.

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November 2020

Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias.

Authors:
Nicole Kucine Sachie Marubayashi Neha Bhagwat Efthymia Papalexi Priya Koppikar Marta Sanchez Martin Lauren Dong Marty S Tallman Elisabeth Paietta Kai Wang Jie He Doron Lipson Phil Stephens Vince Miller Jacob M Rowe Julie Teruya-Feldstein Charles G Mullighan Adolfo A Ferrando Andrei Krivtsov Scott Armstrong Laura Leung Stefan O Ochiana Gabriela Chiosis Ross L Levine Maria Kleppe

Blood 2015 Nov 6;126(22):2479-83. Epub 2015 Oct 6.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY;

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November 2015

JAK-STAT pathway activation in malignant and nonmalignant cells contributes to MPN pathogenesis and therapeutic response.

Authors:
Maria Kleppe Minsuk Kwak Priya Koppikar Markus Riester Matthew Keller Lennart Bastian Todd Hricik Neha Bhagwat Anna Sophia McKenney Efthymia Papalexi Omar Abdel-Wahab Raajit Rampal Sachie Marubayashi Jonathan J Chen Vincent Romanet Jordan S Fridman Jacqueline Bromberg Julie Teruya-Feldstein Masato Murakami Thomas Radimerski Franziska Michor Rong Fan Ross L Levine

Cancer Discov 2015 Mar 8;5(3):316-31. Epub 2015 Jan 8.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York. Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

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March 2015

Genetic studies reveal an unexpected negative regulatory role for Jak2 in thrombopoiesis.

Authors:
Sara C Meyer Matthew D Keller Brittany A Woods Lindsay M LaFave Lennart Bastian Maria Kleppe Neha Bhagwat Sachie Marubayashi Ross L Levine

Blood 2014 Oct 12;124(14):2280-4. Epub 2014 Aug 12.

Human Oncology and Pathogenesis Program, Gerstner Sloan Kettering School of Biomedical Sciences, and Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.

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October 2014

Improved targeting of JAK2 leads to increased therapeutic efficacy in myeloproliferative neoplasms.

Authors:
Neha Bhagwat Priya Koppikar Matthew Keller Sachie Marubayashi Kaitlyn Shank Raajit Rampal Jun Qi Maria Kleppe Hardik J Patel Smit K Shah Tony Taldone James E Bradner Gabriela Chiosis Ross L Levine

Blood 2014 Mar 27;123(13):2075-83. Epub 2014 Jan 27.

Human Oncology and Pathogenesis Program.

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March 2014

Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy.

Authors:
Priya Koppikar Neha Bhagwat Outi Kilpivaara Taghi Manshouri Mazhar Adli Todd Hricik Fan Liu Lindsay M Saunders Ann Mullally Omar Abdel-Wahab Laura Leung Abby Weinstein Sachie Marubayashi Aviva Goel Mithat Gönen Zeev Estrov Benjamin L Ebert Gabriela Chiosis Stephen D Nimer Bradley E Bernstein Srdan Verstovsek Ross L Levine

Nature 2012 Sep;489(7414):155-9

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

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September 2012

Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition.

Authors:
Oliver Weigert Andrew A Lane Liat Bird Nadja Kopp Bjoern Chapuy Diederik van Bodegom Angela V Toms Sachie Marubayashi Amanda L Christie Michael McKeown Ronald M Paranal James E Bradner Akinori Yoda Christoph Gaul Eric Vangrevelinghe Vincent Romanet Masato Murakami Ralph Tiedt Nicolas Ebel Emeline Evrot Alain De Pover Catherine H Régnier Dirk Erdmann Francesco Hofmann Michael J Eck Stephen E Sallan Ross L Levine Andrew L Kung Fabienne Baffert Thomas Radimerski David M Weinstock

J Exp Med 2012 Feb 23;209(2):259-73. Epub 2012 Jan 23.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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February 2012

HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans.

Authors:
Sachie Marubayashi Priya Koppikar Tony Taldone Omar Abdel-Wahab Nathan West Neha Bhagwat Eloisi Caldas-Lopes Kenneth N Ross Mithat Gönen Alex Gozman James H Ahn Anna Rodina Ouathek Ouerfelli Guangbin Yang Cyrus Hedvat James E Bradner Gabriela Chiosis Ross L Levine

J Clin Invest 2010 Oct 13;120(10):3578-93. Epub 2010 Sep 13.

Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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October 2010

Efficacy of the JAK2 inhibitor INCB16562 in a murine model of MPLW515L-induced thrombocytosis and myelofibrosis.

Authors:
Priya Koppikar Omar Abdel-Wahab Cyrus Hedvat Sachie Marubayashi Jay Patel Aviva Goel Nicole Kucine Jeffrey R Gardner Andrew P Combs Kris Vaddi Patrick J Haley Timothy C Burn Mark Rupar Jacqueline F Bromberg Mark L Heaney Elisa de Stanchina Jordan S Fridman Ross L Levine

Blood 2010 Apr 12;115(14):2919-27. Epub 2010 Feb 12.

Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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April 2010

A germline JAK2 SNP is associated with predisposition to the development of JAK2(V617F)-positive myeloproliferative neoplasms.

Authors:
Outi Kilpivaara Semanti Mukherjee Alison M Schram Martha Wadleigh Ann Mullally Benjamin L Ebert Adam Bass Sachie Marubayashi Adriana Heguy Guillermo Garcia-Manero Hagop Kantarjian Kenneth Offit Richard M Stone D Gary Gilliland Robert J Klein Ross L Levine

Nat Genet 2009 Apr 15;41(4):455-9. Epub 2009 Mar 15.

Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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April 2009