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Department of Biochemistry and Molecular Biology, UT MD Anderson Cancer Center, Houston, TX, USA; Center for Stem Cell and Developmental Biology, UT MD Anderson Cancer Center, Houston, TX, USA; Center for Cancer Epigenetics, UT MD Anderson Cancer Center, Houston, TX, USA; Graduate Program in Genes and Development, University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX, USA. Electronic address: