Sabine Uhles

Sabine Uhles

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Sabine Uhles

Sabine Uhles

Publications by authors named "Sabine Uhles"

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14Publications

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Efficacy of simultaneous VEGF-A/ANG-2 neutralization in suppressing spontaneous choroidal neovascularization.

EMBO Mol Med 2019 May;11(5)

Ophthalmology Discovery, Pharma Research& Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.

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http://dx.doi.org/10.15252/emmm.201810204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505683PMC
May 2019

DDR1 role in fibrosis and its pharmacological targeting.

Biochim Biophys Acta Mol Cell Res 2019 Apr 5:118474. Epub 2019 Apr 5.

Roche Pharma Research and Early Development, Roche Innovation Center Basel, Switzerland; School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2019.04.004DOI Listing
April 2019

Insulin-feedback via PI3K-C2alpha activated PKBalpha/Akt1 is required for glucose-stimulated insulin secretion.

FASEB J 2010 Jun 8;24(6):1824-37. Epub 2010 Jan 8.

Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Stockholm, Sweden.

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http://www.fasebj.org/doi/10.1096/fj.09-148072
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http://dx.doi.org/10.1096/fj.09-148072DOI Listing
June 2010

Selective gene activation by spatial segregation of insulin receptor B signaling.

FASEB J 2007 May 30;21(7):1609-21. Epub 2007 Jan 30.

The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, S-171 76 Stockholm, Sweden.

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http://www.fasebj.org/doi/10.1096/fj.06-7589com
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http://dx.doi.org/10.1096/fj.06-7589comDOI Listing
May 2007

The 14-3-3 protein translates the NA+,K+-ATPase {alpha}1-subunit phosphorylation signal into binding and activation of phosphoinositide 3-kinase during endocytosis.

J Biol Chem 2005 Apr 18;280(16):16272-7. Epub 2005 Feb 18.

Department of Medicine, Atherosclerosis Research Unit, Membrane Signaling Networks, Karolinska Institutet, Karolinska University Hospital-Solna, S-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1074/jbc.M500486200DOI Listing
April 2005

Apolipoprotein CIII promotes Ca2+-dependent beta cell death in type 1 diabetes.

Proc Natl Acad Sci U S A 2004 Jul 21;101(27):10090-4. Epub 2004 Jun 21.

Department of Molecular Medicine, Rolf Luft Center for Diabetes Research, Karolinska Institutet, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1073/pnas.0403551101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC454169PMC
July 2004

Interferon alpha-induced apoptosis in tumor cells is mediated through the phosphoinositide 3-kinase/mammalian target of rapamycin signaling pathway.

J Biol Chem 2004 Jun 31;279(23):24152-62. Epub 2004 Mar 31.

Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Hospital and Institute, S-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1074/jbc.M312219200DOI Listing
June 2004

Isoform-specific insulin receptor signaling involves different plasma membrane domains.

J Cell Biol 2003 Dec;163(6):1327-37

The Rolf Luft Center for Diabetes Research, Department of Molecular Medicine, Karolinska Institutet, S-171 76 Stockholm, Sweden.

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http://www.jcb.org/lookup/doi/10.1083/jcb.200306093
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http://dx.doi.org/10.1083/jcb.200306093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173728PMC
December 2003