Sabine C Linn

Sabine C Linn

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Sabine C Linn

Publications by authors named "Sabine C Linn"

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IGF-1R pathway activation as putative biomarker for linsitinib therapy to revert tamoxifen resistance in ER-positive breast cancer.

Int J Cancer 2019 Sep 6. Epub 2019 Sep 6.

Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/ijc.32668DOI Listing
September 2019

[Freud and colorectal cancer guideline adherence in the Netherlands].

Authors:
Sabine C Linn

Ned Tijdschr Geneeskd 2018 07 5;162. Epub 2018 Jul 5.

Antoni van Leeuwenhoek, afd. Medische oncologie, Amsterdam en UMC Utrecht, afd. Pathologie.

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July 2018

PARP Inhibitors in the Treatment of Triple-Negative Breast Cancer.

Clin Pharmacokinet 2018 04;57(4):427-437

Department of Clinical Pharmacology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, 1066 CX, The Netherlands.

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http://dx.doi.org/10.1007/s40262-017-0587-4DOI Listing
April 2018

[Living with incurable cancer].

Ned Tijdschr Geneeskd 2016 ;160:A9615

Antoni van Leeuwenhoek, Amsterdam.

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October 2017

Neoadjuvant Therapy for Breast Cancer: Established Concepts and Emerging Strategies.

Drugs 2017 Aug;77(12):1313-1336

Department of Medical Oncology, Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s40265-017-0774-5DOI Listing
August 2017

Impact of 70-Gene Signature Use on Adjuvant Chemotherapy Decisions in Patients With Estrogen Receptor-Positive Early Breast Cancer: Results of a Prospective Cohort Study.

J Clin Oncol 2017 Aug 13;35(24):2814-2819. Epub 2017 Mar 13.

Anne Kuijer, Marieke Straver, Bianca den Dekker, Annelotte C.M. van Bommel, and Thijs van Dalen, Diakonessenhuis; Anne Kuijer, Sjoerd G. Elias, Sabine C. Linn, and Thijs van Dalen, University Medical Centre Utrecht; Sabine Siesling, Netherlands Comprehensive Cancer Organization, Utrecht; Carolien H. Smorenburg and Jelle Wesseling, Antoni van Leeuwenhoek Hospital; Carolien H. Smorenburg, Jelle Wesseling, Sabine C. Linn, and Emiel J.Th. Rutgers, Netherlands Cancer Institute, Amsterdam; and Sabine Siesling, University of Twente, Enschede, the Netherlands.

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http://ascopubs.org/doi/10.1200/JCO.2016.70.3959
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http://dx.doi.org/10.1200/JCO.2016.70.3959DOI Listing
August 2017

Accuracy of the online prognostication tools PREDICT and Adjuvant! for early-stage breast cancer patients younger than 50 years.

Eur J Cancer 2017 06 14;78:37-44. Epub 2017 Apr 14.

Division of Psychosocial Research and Epidemiology, Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands; Division of Molecular Pathology, Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.03.015DOI Listing
June 2017

(Very) Early technology assessment and translation of predictive biomarkers in breast cancer.

Cancer Treat Rev 2017 Jan 30;52:117-127. Epub 2016 Nov 30.

Department of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands; Department of Healthcare Technology and Services Research, University of Twente, Drienerlolaan 5, 7522 NB, Enschede, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2016.11.008DOI Listing
January 2017

Low risk of recurrence in elderly patients treated with breast conserving therapy in a single institute.

Breast 2016 Dec 29;30:19-25. Epub 2016 Aug 29.

Department of Radiation Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.breast.2016.08.004DOI Listing
December 2016

Erratum to: The effect of trastuzumab-based chemotherapy in small node-negative HER2-positive breast cancer.

Breast Cancer Res Treat 2016 09;159(2):393

Department of Medical Oncology, Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10549-016-3941-6DOI Listing
September 2016

10 year survival after breast-conserving surgery plus radiotherapy compared with mastectomy in early breast cancer in the Netherlands: a population-based study.

Lancet Oncol 2016 08 22;17(8):1158-1170. Epub 2016 Jun 22.

Department of Research, Netherlands Comprehensive Cancer Organisation, Utrecht, Netherlands; Department of Health Technology and Services Research, MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, Enschede, Netherlands. Electronic address:

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http://www.thelancet.com/pdfs/journals/lanonc/PIIS1470-2045(
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http://dx.doi.org/10.1016/S1470-2045(16)30067-5DOI Listing
August 2016

The effect of trastuzumab-based chemotherapy in small node-negative HER2-positive breast cancer.

Breast Cancer Res Treat 2016 07 29;158(2):361-71. Epub 2016 Jun 29.

Department of Medical Oncology, Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10549-016-3878-9DOI Listing
July 2016

The Melanoma MAICare Framework: A Microsimulation Model for the Assessment of Individualized Cancer Care.

Cancer Inform 2016 15;15:115-27. Epub 2016 Jun 15.

Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.4137/CIN.S38122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912231PMC
June 2016

Targeted MS Assay Predicting Tamoxifen Resistance in Estrogen-Receptor-Positive Breast Cancer Tissues and Sera.

J Proteome Res 2016 Apr 18;15(4):1230-42. Epub 2016 Mar 18.

Erasmus University Medical Center Rotterdam , Erasmus MC Cancer Institute, Department of Medical Oncology, 3015 CN Rotterdam, The Netherlands.

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http://dx.doi.org/10.1021/acs.jproteome.5b01119DOI Listing
April 2016

4-protein signature predicting tamoxifen treatment outcome in recurrent breast cancer.

Mol Oncol 2016 Jan 7;10(1):24-39. Epub 2015 Aug 7.

Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center, Wytemaweg 80, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2015.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528925PMC
January 2016

High XIST and Low 53BP1 Expression Predict Poor Outcome after High-Dose Alkylating Chemotherapy in Patients with a BRCA1-like Breast Cancer.

Mol Cancer Ther 2016 Jan 4;15(1):190-8. Epub 2015 Dec 4.

Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands. Department of Pathology, University Medical Center Utrecht, Utrecht, the Netherlands. Division of Medical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0470DOI Listing
January 2016

Dried Blood Spot Self-Sampling at Home for the Individualization of Tamoxifen Treatment: A Feasibility Study.

Ther Drug Monit 2015 Dec;37(6):833-6

*Department of Pharmacy and Pharmacology, The Netherlands Cancer Institute/Slotervaart Hospital, Amsterdam †Department of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam ‡Department of Pathology, University Medical Center Utrecht, Utrecht §Department of Clinical Pharmacology, The Netherlands Cancer Institute, Amsterdam ¶Faculty of Science, Utrecht Institute of Pharmaceutical Sciences, Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, the Netherlands.

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http://pdfs.journals.lww.com/drug-monitoring/2015/12000/Drie
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http://dx.doi.org/10.1097/FTD.0000000000000224DOI Listing
December 2015

Copy number profiling by array comparative genomic hybridization identifies frequently occurring BRCA2-like male breast cancer.

Genes Chromosomes Cancer 2015 Dec 10;54(12):734-44. Epub 2015 Sep 10.

Department of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/gcc.22284DOI Listing
December 2015

Ongoing Remission Nineteen Years after High-dose Chemotherapy for Oligometastatic Breast Cancer; What Can We Learn from this Patient?

Cureus 2015 Dec 24;7(12):e433. Epub 2015 Dec 24.

Department of Medical Oncology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands.

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http://dx.doi.org/10.7759/cureus.433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727954PMC
December 2015

Cognitive effects of endocrine therapy for breast cancer: keep calm and carry on?

Nat Rev Clin Oncol 2015 Oct 21;12(10):597-606. Epub 2015 Jul 21.

Department of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX Amsterdam, Netherlands.

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http://dx.doi.org/10.1038/nrclinonc.2015.124DOI Listing
October 2015

Robust BRCA1-like classification of copy number profiles of samples repeated across different datasets and platforms.

Mol Oncol 2015 Aug 20;9(7):1274-86. Epub 2015 Mar 20.

Department of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands; Division of Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2015.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528812PMC
August 2015

Effects of Pharmacogenetics on the Pharmacokinetics and Pharmacodynamics of Tamoxifen.

Clin Pharmacokinet 2015 Aug;54(8):797-810

Department of Pharmacy and Pharmacology, Antoni van Leeuwenhoek-The Netherlands Cancer Institute, Louwesweg 6, 1066 EC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s40262-015-0273-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513218PMC
August 2015

Tailored Tamoxifen Treatment for Breast Cancer Patients: A Perspective.

Clin Breast Cancer 2015 Aug 23;15(4):241-4. Epub 2015 Apr 23.

Department of Pharmacy and Pharmacology, The Netherlands Cancer Institute/Slotervaart Hospital, Amsterdam, The Netherlands; Department of Clinical Pharmacology, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Faculty of Science, Utrecht Institute of Pharmaceutical Sciences (UIPS), Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.clbc.2015.04.005DOI Listing
August 2015

Challenges in the Use of DNA Repair Deficiency As a Biomarker in Breast Cancer.

J Clin Oncol 2015 Jun 27;33(17):1867-9. Epub 2015 Apr 27.

Netherlands Cancer Institute, Amsterdam, and University Medical Center Utrecht, Utrecht, the Netherlands

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http://dx.doi.org/10.1200/JCO.2014.60.5501DOI Listing
June 2015

Molecular profiling is rather likely to be cost effective.

J Clin Oncol 2015 May 6;33(14):1626-7. Epub 2015 Apr 6.

Netherlands Cancer Institute, Amsterdam; and University of Twente, School of Governance and Management, Enschede, the Netherlands

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http://dx.doi.org/10.1200/JCO.2014.59.8029DOI Listing
May 2015

Lack of genomic heterogeneity at high-resolution aCGH between primary breast cancers and their paired lymph node metastases.

PLoS One 2014 1;9(8):e103177. Epub 2014 Aug 1.

Division of Molecular Pathology, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands; Division of Medical Oncology, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0103177PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118860PMC
April 2015

Breast cancers with a BRCA1-like DNA copy number profile recur less often than expected after high-dose alkylating chemotherapy.

Clin Cancer Res 2015 Feb 5;21(4):763-70. Epub 2014 Dec 5.

Department of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands. Division of Medical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands. Department of Pathology, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1894DOI Listing
February 2015

[Gene expression classifiers in the prognosis of breast cancer].

Ned Tijdschr Geneeskd 2014 ;158:A7001

Nederlands Kanker Instituut-Antoni van Leeuwenhoek ziekenhuis, Amsterdam.

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December 2014

PI3K/AKT/mTOR pathway activation in primary and corresponding metastatic breast tumors after adjuvant endocrine therapy.

Int J Cancer 2014 Sep 27;135(5):1257-63. Epub 2014 Feb 27.

Department of Molecular Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/ijc.28769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277331PMC
September 2014

Dynamics of IGF-1R expression during endocrine breast cancer treatment.

Mol Imaging Biol 2014 Aug;16(4):529-37

Department of Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands,

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http://dx.doi.org/10.1007/s11307-014-0723-6DOI Listing
August 2014

Paclitaxel, carboplatin, and trastuzumab in a neo-adjuvant regimen for HER2-positive breast cancer.

Breast J 2013 Jul-Aug;19(4):419-26. Epub 2013 May 20.

Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/tbj.12124DOI Listing
February 2014

Hot flashes are not predictive for serum concentrations of tamoxifen and its metabolites.

BMC Cancer 2013 Dec 28;13:612. Epub 2013 Dec 28.

Department of Pharmacy & Pharmacology, Slotervaart Hospital/The Netherlands Cancer Institute, Louwesweg 6, 1066 EC Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/1471-2407-13-612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880169PMC
December 2013

Hallmarks of aromatase inhibitor drug resistance revealed by epigenetic profiling in breast cancer.

Cancer Res 2013 Nov;73(22):6632-41

Authors' Affiliations: Department of Medical Oncology, Erasmus University Medical Center, Cancer Institute, Rotterdam; Departments of Molecular Carcinogenesis and Molecular Pathology, Central Genomic Facility, the Netherlands Cancer Institute; Agendia NV, Amsterdam, the Netherlands; and Translational Cancer Research Unit, Laboratory of Pathology, Antwerp University/Oncology Centre, GZA Hospitals St-Augustinus, Antwerp, Belgium.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0704DOI Listing
November 2013

Platform comparisons for identification of breast cancers with a BRCA-like copy number profile.

Breast Cancer Res Treat 2013 Jun 14;139(2):317-27. Epub 2013 May 14.

Division of Molecular Pathology, Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10549-013-2558-2DOI Listing
June 2013

Hotspot mutations in PIK3CA associate with first-line treatment outcome for aromatase inhibitors but not for tamoxifen.

Breast Cancer Res Treat 2013 May 17;139(1):39-49. Epub 2013 Apr 17.

Department of Medical Oncology, Erasmus MC Cancer Institute, Room Be424, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10549-013-2529-7DOI Listing
May 2013

Can predictive biomarkers in breast cancer guide adjuvant endocrine therapy?

Nat Rev Clin Oncol 2012 Sep 24;9(9):529-41. Epub 2012 Jul 24.

Department of Molecular Pathology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/nrclinonc.2012.121DOI Listing
September 2012

Scenario drafting to anticipate future developments in technology assessment.

BMC Res Notes 2012 Aug 16;5:442. Epub 2012 Aug 16.

Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital (NKI-AVL), Department of Psychosocial Research and Epidemiology, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands.

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http://dx.doi.org/10.1186/1756-0500-5-442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444406PMC
August 2012

Genomic instability in breast and ovarian cancers: translation into clinical predictive biomarkers.

Cell Mol Life Sci 2012 Jan 16;69(2):223-45. Epub 2011 Sep 16.

Division of Molecular Biology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00018-011-0809-0DOI Listing
January 2012

Metastatic potential of T1 breast cancer can be predicted by the 70-gene MammaPrint signature.

Ann Surg Oncol 2010 May 22;17(5):1406-13. Epub 2010 Jan 22.

Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1245/s10434-009-0902-xDOI Listing
May 2010

Cost-effectiveness of the 70-gene signature versus St. Gallen guidelines and Adjuvant Online for early breast cancer.

Eur J Cancer 2010 May 30;46(8):1382-91. Epub 2010 Mar 30.

Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital (NKI-AVL), Department of Psychosocial Research and Epidemiology, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S095980491000162
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http://dx.doi.org/10.1016/j.ejca.2010.02.035DOI Listing
May 2010

The predictive value of the 70-gene signature for adjuvant chemotherapy in early breast cancer.

Breast Cancer Res Treat 2010 Apr 5;120(3):655-61. Epub 2010 Mar 5.

Division of Diagnostic Oncology, Netherlands Cancer Institute, Plesmanlaan, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10549-010-0814-2DOI Listing
April 2010

Isolated tumor cells in breast cancer.

N Engl J Med 2009 Nov;361(20):1995; author reply 1995-6

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November 2009

Clinical relevance of the triple-negative breast cancer concept: genetic basis and clinical utility of the concept.

Eur J Cancer 2009 Sep;45 Suppl 1:11-26

Division of Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/S0959-8049(09)70012-7DOI Listing
September 2009

Accurate axillary lymph node dissection is feasible after neoadjuvant chemotherapy.

Am J Surg 2009 Jul 17;198(1):46-50. Epub 2008 Dec 17.

Department of Surgery, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.amjsurg.2008.05.006DOI Listing
July 2009

Mammosphere-derived gene set predicts outcome in patients with ER-positive breast cancer.

J Pathol 2009 Jul;218(3):316-26

Departments of Pathology, Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/path.2544DOI Listing
July 2009

Molecular tests for breast-cancer diagnosis?

Lancet Oncol 2009 Apr;10(4):314-5

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http://dx.doi.org/10.1016/S1470-2045(09)70070-1DOI Listing
April 2009

Treating the genetic make-up of breast cancer: a new fashion?

Expert Rev Anticancer Ther 2007 Aug;7(8):1065-7

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http://dx.doi.org/10.1586/14737140.7.8.1065DOI Listing
August 2007