Sabine Bahn

Sabine Bahn

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Sabine Bahn

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Converging evidence points towards a role of insulin signaling in regulating compulsive behavior.

Transl Psychiatry 2019 Sep 12;9(1):225. Epub 2019 Sep 12.

Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s41398-019-0559-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742634PMC
September 2019

Increased serum levels of leptin and insulin in both schizophrenia and major depressive disorder: A cross-disorder proteomics analysis.

Eur Neuropsychopharmacol 2019 Jul 21;29(7):835-846. Epub 2019 Jun 21.

Antes Center for Mental Health Care, Poortugaal, the Netherlands; Department of Psychiatry, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Neuroscience, Erasmus Medical Center, Rotterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2019.05.010DOI Listing
July 2019

Evaluation of molecular brain changes associated with environmental stress in rodent models compared to human major depressive disorder: A proteomic systems approach.

World J Biol Psychiatry 2018 25;19(sup2):S63-S74. Epub 2016 Nov 25.

a Department of Chemical Engineering and Biotechnology , University of Cambridge , Cambridge , United Kingdom.

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http://dx.doi.org/10.1080/15622975.2016.1252465DOI Listing
June 2019

Multimodel inference for biomarker development: an application to schizophrenia.

Transl Psychiatry 2019 02 11;9(1):83. Epub 2019 Feb 11.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/s41398-019-0419-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370882PMC
February 2019

Clinical Trials and Therapeutic Rationale for Drug Repurposing in Schizophrenia.

ACS Chem Neurosci 2019 01 18;10(1):58-78. Epub 2018 Jul 18.

Department of Chemical Engineering and Biotechnology , University of Cambridge , Cambridge CB3 0AS , U.K.

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http://dx.doi.org/10.1021/acschemneuro.8b00205DOI Listing
January 2019

Virus discovery analyses on post-mortem brain tissue and cerebrospinal fluid of schizophrenia patients.

Schizophr Res 2018 Jul 23;197:605-606. Epub 2018 Feb 23.

Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09209964183008
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http://dx.doi.org/10.1016/j.schres.2018.02.012DOI Listing
July 2018

A brain proteomic investigation of rapamycin effects in the mouse model.

Mol Autism 2017 1;8:41. Epub 2017 Aug 1.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QT UK.

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http://dx.doi.org/10.1186/s13229-017-0151-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540199PMC
April 2018

Allostatic load is associated with psychotic symptoms and decreases with antipsychotic treatment in patients with schizophrenia and first-episode psychosis.

Psychoneuroendocrinology 2018 04 5;90:35-42. Epub 2018 Feb 5.

Laboratory of Psychiatric Neuroscience, Australian Institute of Tropical Health and Medicine (AITHM), 1 James Cook Drive, Townsville, QLD, 4811, Australia, Australia; College of Public Health, Medical and Veterinary Science, James Cook University, 1 James Cook Drive, Townsville, QLD, 4811, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.psyneuen.2018.02.001DOI Listing
April 2018

Proteomic approaches to identify blood-based biomarkers for depression and bipolar disorders.

Expert Rev Proteomics 2018 04 27;15(4):325-340. Epub 2018 Feb 27.

a Department of Chemical Engineering and Biotechnology , University of Cambridge , Cambridge , UK.

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http://dx.doi.org/10.1080/14789450.2018.1444483DOI Listing
April 2018

Evidence of microglial activation following exposure to serum from first-onset drug-naïve schizophrenia patients.

Brain Behav Immun 2018 Jan 4;67:364-373. Epub 2017 Oct 4.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2017.10.003DOI Listing
January 2018

Associations between SNPs and immune-related circulating proteins in schizophrenia.

Sci Rep 2017 10 3;7(1):12586. Epub 2017 Oct 3.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1038/s41598-017-12986-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626704PMC
October 2017

Identification of an Immune-Neuroendocrine Biomarker Panel for Detection of Depression: A Joint Effects Statistical Approach.

Neuroendocrinology 2016 19;103(6):693-710. Epub 2015 Nov 19.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1159/000442208DOI Listing
May 2017

Altered apolipoprotein C expression in association with cognition impairments and hippocampus volume in schizophrenia and bipolar disorder.

Eur Arch Psychiatry Clin Neurosci 2017 Apr 22;267(3):199-212. Epub 2016 Aug 22.

Laboratory for Neuroimaging, Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, Goethe University, Heinrich-Hoffmann-Str. 10, 60528, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1007/s00406-016-0724-3DOI Listing
April 2017

Lithium reverses behavioral and axonal transport-related changes associated with ANK3 bipolar disorder gene disruption.

Eur Neuropsychopharmacol 2017 03 18;27(3):274-288. Epub 2017 Jan 18.

Cambridge Centre for Neuropsychiatric Research, Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0924977X173000
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http://dx.doi.org/10.1016/j.euroneuro.2017.01.001DOI Listing
March 2017

Parallel changes in serum proteins and diffusion tensor imaging in methamphetamine-associated psychosis.

Sci Rep 2017 03 2;7:43777. Epub 2017 Mar 2.

Department of Psychiatry and Mental Health, and MRC Unit on Anxiety &Stress Disorders, University of Cape Town, South Africa.

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http://dx.doi.org/10.1038/srep43777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333148PMC
March 2017

Towards reproducible MRM based biomarker discovery using dried blood spots.

Sci Rep 2017 03 27;7:45178. Epub 2017 Mar 27.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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http://www.nature.com/articles/srep45178
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http://dx.doi.org/10.1038/srep45178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366927PMC
March 2017

Blood-based immune-endocrine biomarkers of treatment response in depression.

J Psychiatr Res 2016 12 31;83:249-259. Epub 2016 Aug 31.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2016.08.020DOI Listing
December 2016

Proteomic systems evaluation of the molecular validity of preclinical psychosis models compared to schizophrenia brain pathology.

Schizophr Res 2016 11 19;177(1-3):98-107. Epub 2016 Jun 19.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, CB2 1QT, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2016.06.012DOI Listing
November 2016

Neuroimmune biomarkers in schizophrenia.

Schizophr Res 2016 09 12;176(1):3-13. Epub 2014 Aug 12.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK; Department of Neuroscience, Erasmus Medical Centre, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2014.07.025DOI Listing
September 2016

Molecular serum signature of treatment resistant depression.

Psychopharmacology (Berl) 2016 Aug 20;233(15-16):3051-9. Epub 2016 Jun 20.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1007/s00213-016-4348-0DOI Listing
August 2016

The association between antibodies to neurotropic pathogens and schizophrenia: a case-control study.

NPJ Schizophr 2015 4;1:15041. Epub 2015 Nov 4.

Department of Viroscience, Erasmus University Medical Center , Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/npjschz.2015.41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849462PMC
June 2016

Variation in serum biomarkers with sex and female hormonal status: implications for clinical tests.

Sci Rep 2016 05 31;6:26947. Epub 2016 May 31.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, CB2 1QT, United Kingdom.

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http://dx.doi.org/10.1038/srep26947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886262PMC
May 2016

Cell Type-Specific Effects of Mutant DISC1: A Proteomics Study.

Mol Neuropsychiatry 2016 May 1;2(1):28-36. Epub 2016 Apr 1.

Departments of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Md., USA; Departments of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, Md., USA; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Md., USA; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md., USA.

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http://dx.doi.org/10.1159/000444587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996005PMC
May 2016

Association of DNA Methylation with Acute Mania and Inflammatory Markers.

PLoS One 2015 6;10(7):e0132001. Epub 2015 Jul 6.

Department of Pediatrics, Johns Hopkins University, Baltimore, MD, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132001PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492496PMC
April 2016

Synaptic vesicle dynamic changes in a model of fragile X.

Mol Autism 2016 1;7:17. Epub 2016 Mar 1.

Cambridge Centre for Neuropsychiatric Research, Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1186/s13229-016-0080-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772588PMC
April 2016

Shared Immune and Repair Markers During Experimental Toxoplasma Chronic Brain Infection and Schizophrenia.

Schizophr Bull 2016 Mar 20;42(2):386-95. Epub 2015 Sep 20.

Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI;

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https://academic.oup.com/schizophreniabulletin/article-looku
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http://dx.doi.org/10.1093/schbul/sbv134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753603PMC
March 2016

Pretreatment levels of the fatty acid handling proteins H-FABP and CD36 predict response to olanzapine in recent-onset schizophrenia patients.

Brain Behav Immun 2016 Feb 2;52:178-186. Epub 2015 Nov 2.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK; Department of Neuroscience, Erasmus Medical Centre, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2015.10.019DOI Listing
February 2016

Commercialisation of Biomarker Tests for Mental Illnesses: Advances and Obstacles.

Trends Biotechnol 2015 Dec 6;33(12):712-723. Epub 2015 Nov 6.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/j.tibtech.2015.09.010DOI Listing
December 2015

Effects of olanzapine on serum protein phosphorylation patterns in patients with schizophrenia.

Proteomics Clin Appl 2015 Oct 15;9(9-10):907-16. Epub 2015 May 15.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/prca.201400148DOI Listing
October 2015

Multiplex immunoassay analysis of plasma shows differences in biomarkers related to manic or mixed mood states in bipolar disorder patients.

J Affect Disord 2015 Oct 24;185:12-6. Epub 2015 Jun 24.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2015.05.065DOI Listing
October 2015

Multianalyte markers of schizophrenia and bipolar disorder: A preliminary study.

Schizophr Res 2015 Oct 19;168(1-2):450-5. Epub 2015 Aug 19.

Johns Hopkins School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.schres.2015.08.003DOI Listing
October 2015

Hippocampal Proteomic and Metabonomic Abnormalities in Neurotransmission, Oxidative Stress, and Apoptotic Pathways in a Chronic Phencyclidine Rat Model.

J Proteome Res 2015 Aug 30;14(8):3174-87. Epub 2015 Jun 30.

†Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB2 1QT, U.K.

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http://pubs.acs.org/doi/10.1021/acs.jproteome.5b00105
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http://dx.doi.org/10.1021/acs.jproteome.5b00105DOI Listing
August 2015

Immunomodulatory Effects of Probiotic Supplementation in Schizophrenia Patients: A Randomized, Placebo-Controlled Trial.

Biomark Insights 2015 1;10:47-54. Epub 2015 Jun 1.

Stanley Research Program at Sheppard Pratt, Sheppard Pratt Health System, Baltimore, MD, USA.

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http://journals.sagepub.com/doi/10.4137/BMI.S22007
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http://dx.doi.org/10.4137/BMI.S22007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454091PMC
June 2015

The potential of immune biomarkers to advance personalized medicine approaches for schizophrenia.

J Nerv Ment Dis 2015 May;203(5):393-9

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1097/NMD.0000000000000289DOI Listing
May 2015

Biomarkers for Psychiatry: The Journey from Fantasy to Fact, a Report of the 2013 CINP Think Tank.

Int J Neuropsychopharmacol 2015 Apr 21;18(10):pyv042. Epub 2015 Apr 21.

Department of Psychiatry, University of Melbourne, Victoria, Australia (Drs Scarr and Dean); The Molecular Psychiatry Laboratory, Florey Institute for Neuroscience and Mental Health, Victoria, Australia (Drs Scarr and Dean); Pole d'Innovation Thérapeutique en Neuropsychiatrie, Institut de Recherches Servier, Paris, France (Dr Millan); Cambridge Centre for Neuropsychiatric Research, University of Cambridge, UK (Dr Bahn); Pharma Research & Early Development, NORD, DTA, Hoffman - La Roche, Ltd., Basel, Switzerland (Dr Bertolino); School of Medicine, Basic Medical Sciences, Neuroscience and Sense Organs (DMBNOS), University of Bari, Italy (Dr Bertolino); Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany (Dr Turck); Institute of Psychiatry, Kings College London, London, UK (Dr Kapur); Department of Psychiatry, Ludwig-Maximilians-University, Munich, Germany (Dr Möller).

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http://dx.doi.org/10.1093/ijnp/pyv042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648162PMC
April 2015

What can we learn about depression from gene expression in peripheral tissues?

Biol Psychiatry 2015 Feb;77(3):207-209

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2014.10.019DOI Listing
February 2015

Investigation of molecular serum profiles associated with predisposition to antipsychotic-induced weight gain.

World J Biol Psychiatry 2015 Jan 3;16(1):22-30. Epub 2013 Sep 3.

Department of Chemical Engineering and Biotechnology, University of Cambridge , Cambridge , UK.

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http://dx.doi.org/10.3109/15622975.2013.817685DOI Listing
January 2015

A targeted multiplexed proteomic investigation identifies ketamine-induced changes in immune markers in rat serum and expression changes in protein kinases/phosphatases in rat brain.

J Proteome Res 2015 Jan 19;14(1):411-21. Epub 2014 Nov 19.

Department of Chemical Engineering and Biotechnology, University of Cambridge , Cambridge CB2 1QT, United Kingdom.

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http://dx.doi.org/10.1021/pr5009493DOI Listing
January 2015

Distinct proteomic profiles in post-mortem pituitary glands from bipolar disorder and major depressive disorder patients.

J Psychiatr Res 2015 Jan 8;60:40-8. Epub 2014 Oct 8.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Tennis Court Road, Cambridge CB21QT, UK; Department of Neuroscience, Erasmus MC, NL-3015 GE Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2014.09.022DOI Listing
January 2015

Applications of blood-based protein biomarker strategies in the study of psychiatric disorders.

Prog Neurobiol 2014 Nov 27;122:45-72. Epub 2014 Aug 27.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QT, United Kingdom; Department of Neuroscience, Erasmus MC, Wytemaweg 80, NL-3015 CN Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.pneurobio.2014.08.002DOI Listing
November 2014

Proteomic changes in serum of first onset, antidepressant drug-naïve major depression patients.

Int J Neuropsychopharmacol 2014 Oct 5;17(10):1599-608. Epub 2014 Jun 5.

Department of Chemical Engineering and Biotechnology,University of Cambridge,Cambridge,UK.

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http://dx.doi.org/10.1017/S1461145714000819DOI Listing
October 2014

Targeted multiplexed selected reaction monitoring analysis evaluates protein expression changes of molecular risk factors for major psychiatric disorders.

Int J Neuropsychopharmacol 2014 Oct 31;18(1). Epub 2014 Oct 31.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB2 1QT, United Kingdom (Wesseling, Gottschalk, and Bahn); Department of Neuroscience, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands (Dr Bahn).H.W. and M.G.G. contributed equally to this work.

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http://dx.doi.org/10.1093/ijnp/pyu015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368865PMC
October 2014

Proteomic enrichment analysis of psychotic and affective disorders reveals common signatures in presynaptic glutamatergic signaling and energy metabolism.

Int J Neuropsychopharmacol 2014 Oct 31;18(2). Epub 2014 Oct 31.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK (Drs Gottschalk, Wesseling, and Drs Guest and Bahn); Department of Neuroscience, Erasmus Medical Center, Rotterdam, The Netherlands (Dr Bahn).

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http://dx.doi.org/10.1093/ijnp/pyu019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368887PMC
October 2014

Technological advances for deciphering the complexity of psychiatric disorders: merging proteomics with cell biology.

Int J Neuropsychopharmacol 2014 Aug 14;17(8):1327-41. Epub 2014 Feb 14.

Department of Chemical Engineering and Biotechnology,University of Cambridge,Cambridge CB2 1QT,UK.

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http://dx.doi.org/10.1017/S146114571400008XDOI Listing
August 2014

Proteomic analysis of post mortem brain tissue from autism patients: evidence for opposite changes in prefrontal cortex and cerebellum in synaptic connectivity-related proteins.

Mol Autism 2014 30;5:41. Epub 2014 Jul 30.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Tennis Court Road, CB2 1QT Cambridge, UK ; Department of Neuroscience, Erasmus Medical Centre, Dr. Molenwaterplein 50, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1186/2040-2392-5-41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131484PMC
August 2014

Identification of subgroups of schizophrenia patients with changes in either immune or growth factor and hormonal pathways.

Schizophr Bull 2014 Jul 9;40(4):787-95. Epub 2013 Aug 9.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK; Department of Neuroscience, Erasmus University Medical Centre, Rotterdam, the Netherlands

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http://dx.doi.org/10.1093/schbul/sbt105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059436PMC
July 2014

The use of proteomic biomarkers for improved diagnosis and stratification of schizophrenia patients.

Biomark Med 2014 ;8(1):15-27

Department of Chemical Engineering & Biotechnology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.2217/bmm.13.83DOI Listing
July 2014

Integrative proteomic analysis of the NMDA NR1 knockdown mouse model reveals effects on central and peripheral pathways associated with schizophrenia and autism spectrum disorders.

Mol Autism 2014 4;5:38. Epub 2014 Jul 4.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QT, UK ; Department of Neuroscience, Erasmus Medical Center, Rotterdam, CA, 3000, The Netherlands.

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http://dx.doi.org/10.1186/2040-2392-5-38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109791PMC
July 2014

Proteomic profiling in schizophrenia: enabling stratification for more effective treatment.

Genome Med 2013 26;5(3):25. Epub 2013 Mar 26.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QT, UK ; Department of Neuroscience, Erasmus Medical Centre, NL-3000 CA Rotterdam, The Netherlands.

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http://genomemedicine.biomedcentral.com/articles/10.1186/gm4
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http://dx.doi.org/10.1186/gm429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706977PMC
June 2014

Proteomics: improving biomarker translation to modern medicine?

Genome Med 2013 27;5(2):17. Epub 2013 Feb 27.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK ; Department of Neuroscience, Erasmus Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1186/gm421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706758PMC
May 2014

The need for a comprehensive molecular characterization of autism spectrum disorders.

Int J Neuropsychopharmacol 2014 Apr 12;17(4):651-73. Epub 2013 Nov 12.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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https://academic.oup.com/ijnp/article-lookup/doi/10.1017/S14
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http://dx.doi.org/10.1017/S146114571300117XDOI Listing
April 2014

Cytokine alterations in first-episode schizophrenia patients before and after antipsychotic treatment.

Schizophr Res 2014 Apr 26;154(1-3):23-9. Epub 2014 Feb 26.

Department of Chemical Engineering and Biotechnology, Tennis Court Road, Cambridge CB21QT, University of Cambridge, UK; Department of Neuroscience, Erasmus Medical Centre, Dr. Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2014.02.005DOI Listing
April 2014

Identification of protein biomarkers in human serum using iTRAQ and shotgun mass spectrometry.

Methods Mol Biol 2013 ;1061:291-307

Department of Chemical Engineering and Biotechnology, Cambridge Centre for Neuropsychiatric Research, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1007/978-1-62703-589-7_18DOI Listing
March 2014

Multiplex immunoassay analysis of plasma shows prominent upregulation of growth factor activity pathways linked to GSK3β signaling in bipolar patients.

J Affect Disord 2014 Mar 16;156:139-43. Epub 2013 Dec 16.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK; Department of Neuroscience, Erasmus Medical Centre, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2013.12.008DOI Listing
March 2014

Affinity depletion of plasma and serum for mass spectrometry-based proteome analysis.

Methods Mol Biol 2013 ;1002:1-11

University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1007/978-1-62703-360-2_1DOI Listing
February 2014

Identification of altered dipeptidyl-peptidase activities as potential biomarkers for unipolar depression.

J Affect Disord 2013 Nov 31;151(2):667-72. Epub 2013 Jul 31.

Clinical Pharmacology Unit, GlaxoSmithKline, Addenbrooke's Hospital, Cambridge CB2 2GG, UK.

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http://dx.doi.org/10.1016/j.jad.2013.07.015DOI Listing
November 2013

Electroconvulsive therapy exerts mainly acute molecular changes in serum of major depressive disorder patients.

Eur Neuropsychopharmacol 2013 Oct 22;23(10):1199-207. Epub 2012 Nov 22.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2012.10.012DOI Listing
October 2013

Development of a novel assay for proprotein converting enzyme activity on a multiplex bead-based array system.

Proteomics 2013 Oct;13(20):2976-9

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/pmic.201300060DOI Listing
October 2013

Metabolic, hormonal and stress-related molecular changes in post-mortem pituitary glands from schizophrenia subjects.

World J Biol Psychiatry 2013 Sep 17;14(7):478-89. Epub 2012 Jan 17.

Department of Chemical Engineering and Biotechnology, University of Cambridge , Cambridge , UK.

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http://dx.doi.org/10.3109/15622975.2011.601759DOI Listing
September 2013

Identification of an age-dependent biomarker signature in children and adolescents with autism spectrum disorders.

Mol Autism 2013 Aug 6;4(1):27. Epub 2013 Aug 6.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QT, UK.

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http://dx.doi.org/10.1186/2040-2392-4-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751071PMC
August 2013

Application of meta-analysis methods for identifying proteomic expression level differences.

Proteomics 2013 Jul 6;13(14):2072-6. Epub 2013 Jun 6.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/pmic.201300034DOI Listing
July 2013

Schizophrenia: metabolic aspects of aetiology, diagnosis and future treatment strategies.

Psychoneuroendocrinology 2013 Jun 22;38(6):752-66. Epub 2012 Oct 22.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S03064530120032
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http://dx.doi.org/10.1016/j.psyneuen.2012.09.009DOI Listing
June 2013

Comparison of peripheral and central schizophrenia biomarker profiles.

PLoS One 2012 30;7(10):e46368. Epub 2012 Oct 30.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0046368PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484150PMC
May 2013

Challenges in drug target discovery in bipolar disorder.

Expert Opin Ther Targets 2013 May 18;17(5):565-77. Epub 2013 Feb 18.

University of Cambridge, Institute of Biotechnology, Department of Chemical Engineering and Biotechnology , Tennis Court Road, Cambridge, CB2 1QT, Cambridgeshire, UK.

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http://dx.doi.org/10.1517/14728222.2013.771169DOI Listing
May 2013

Phosphoproteomic differences in major depressive disorder postmortem brains indicate effects on synaptic function.

Eur Arch Psychiatry Clin Neurosci 2012 Dec 21;262(8):657-66. Epub 2012 Feb 21.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, Cambridgeshire, UK.

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http://dx.doi.org/10.1007/s00406-012-0301-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491199PMC
December 2012

Clinical use of phosphorylated proteins in blood serum analysed by immobilised metal ion affinity chromatography and mass spectrometry.

J Proteomics 2012 Dec 22;76 Spec No.:36-42. Epub 2012 Feb 22.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QT, United Kingdom.

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http://dx.doi.org/10.1016/j.jprot.2012.02.015DOI Listing
December 2012

Protein phosphorylation patterns in serum from schizophrenia patients and healthy controls.

J Proteomics 2012 Dec 26;76 Spec No.:43-55. Epub 2012 May 26.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QT, United Kingdom.

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http://dx.doi.org/10.1016/j.jprot.2012.05.027DOI Listing
December 2012

Blood test for schizophrenia.

Eur Arch Psychiatry Clin Neurosci 2012 Nov 26;262 Suppl 2:S79-83. Epub 2012 Aug 26.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1007/s00406-012-0354-3DOI Listing
November 2012

Analysis of the rat hypothalamus proteome by data-independent label-free LC-MS/MS.

Proteomics 2012 Nov 19;12(22):3386-92. Epub 2012 Oct 19.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/pmic.201100642DOI Listing
November 2012

Challenges of introducing new biomarker products for neuropsychiatric disorders into the market.

Int Rev Neurobiol 2011 ;101:299-327

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/B97801238771850
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http://dx.doi.org/10.1016/B978-0-12-387718-5.00012-2DOI Listing
August 2012

Antipsychotic treatment of acute paranoid schizophrenia patients with olanzapine results in altered glycosylation of serum glycoproteins.

J Proteome Res 2012 Jul 29;11(7):3743-52. Epub 2012 May 29.

NIBRT Dublin-Oxford Glycobiology Laboratory, National Institute for Bioprocessing Research and Training, Foster Avenue, Mount Merrion, Co., Dublin, Ireland.

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http://dx.doi.org/10.1021/pr300218hDOI Listing
July 2012

Molecular validation of the acute phencyclidine rat model for schizophrenia: identification of translational changes in energy metabolism and neurotransmission.

J Proteome Res 2012 Jul 1;11(7):3704-14. Epub 2012 Jun 1.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB2 1QT, UK.

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http://dx.doi.org/10.1021/pr300197dDOI Listing
July 2012

Analysis of serum and plasma identifies differences in molecular coverage, measurement variability, and candidate biomarker selection.

Proteomics Clin Appl 2012 Jun;6(5-6):297-303

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/prca.201100061DOI Listing
June 2012

Proteomic approaches to unravel the complexity of schizophrenia.

Expert Rev Proteomics 2012 ;9(1):97-108

Department of Chemical Engineering & Biotechnology, Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QT, UK.

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http://dx.doi.org/10.1586/epr.11.70DOI Listing
May 2012

To label or not to label: applications of quantitative proteomics in neuroscience research.

Proteomics 2012 Feb 23;12(4-5):736-47. Epub 2012 Jan 23.

Max Planck Institute of Psychiatry, Proteomics and Biomarkers, Munich, Germany.

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http://dx.doi.org/10.1002/pmic.201100350DOI Listing
February 2012