Sabina A Murphy

Sabina A Murphy

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Sabina A Murphy

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Efficacy and safety of more potent antiplatelet therapy with vorapaxar in patients with impaired renal function.

J Thromb Thrombolysis 2019 Apr;47(3):353-360

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Rd., Suite 7022, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/s11239-018-1779-yDOI Listing
April 2019

Edoxaban and implantable cardiac device interventions: insights from the ENGAGE AF-TIMI 48 trial.

Europace 2019 Feb;21(2):306-312

Cardiovascular Division, TIMI Study Group, Brigham and Women's Hospital, 350 Longwood Avenue, 1st Floor Offices, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/europace/euy253DOI Listing
February 2019

Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes.

N Engl J Med 2019 01 10;380(4):347-357. Epub 2018 Nov 10.

From the Thrombolysis in Myocardial Infarction (TIMI) Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital (S.D.W., M.P.B., T.A.Z., J.F.K., S.A.M., D.L.B., C.T.R., M.S.S.), and the Cardiology Division, Massachusetts General Hospital (M.G.S.) - both in Boston; the Diabetes Unit, Hadassah Hebrew University Hospital, Jerusalem (I.R., O.M., A.C.); the Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (E.T.K.); Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto (L.A.L.); the Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (D.K.M.); Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, United Kingdom (J.P.H.W.); and AstraZeneca Gothenburg, Mölndal, Sweden (I.A.M.G.-N., M.F., P.A.J., A.-M.L.).

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http://dx.doi.org/10.1056/NEJMoa1812389DOI Listing
January 2019

Lorcaserin and Renal Outcomes in Obese and Overweight Patients in the CAMELLIA-TIMI 61 Trial.

Circulation 2019 Jan;139(3):366-375

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (B.M.S., E.A.B., A.Q., S.A.M., K.I., M.P.B., C.T.R., M.S.S., S.D.W.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.038341DOI Listing
January 2019

Cystatin C for Risk Stratification in Patients After an Acute Coronary Syndrome.

J Am Heart Assoc 2018 Oct;7(20):e009077

1 TIMI Study Group Division of Cardiovascular Medicine Brigham and Women's Hospital and Harvard Medical School Boston MA.

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https://www.ahajournals.org/doi/10.1161/JAHA.118.009077
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http://dx.doi.org/10.1161/JAHA.118.009077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474969PMC
October 2018

Efficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels: A Meta-analysis.

JAMA Cardiol 2018 Sep;3(9):823-828

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://cardiology.jamanetwork.com/article.aspx?doi=10.1001/j
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http://dx.doi.org/10.1001/jamacardio.2018.2258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233651PMC
September 2018

Inflammatory and Cholesterol Risk in the FOURIER Trial.

Circulation 2018 Jul 12;138(2):131-140. Epub 2018 Mar 12.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (E.A.B., R.P.G., J.-G.P., S.A.M., M.S.S.).

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.034032DOI Listing
July 2018

Fatal or Irreversible Bleeding and Ischemic Events With Rivaroxaban in Acute Coronary Syndrome.

J Am Coll Cardiol 2018 Jul;72(2):129-136

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2018.04.055DOI Listing
July 2018

Peri-operative Adverse Outcomes in Patients with Atrial Fibrillation Taking Warfarin or Edoxaban: Analysis of the ENGAGE AF-TIMI 48 Trial.

Thromb Haemost 2018 06 3;118(6):1001-1008. Epub 2018 May 3.

Department of Medicine, Brigham and Women's Hospital, Harvard University, Boston, Massachusetts, United States.

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http://dx.doi.org/10.1055/s-0038-1645856DOI Listing
June 2018

Ticagrelor for Secondary Prevention of Atherothrombotic Events in Patients With Multivessel Coronary Disease.

J Am Coll Cardiol 2018 Feb;71(5):489-496

Department of Cardiology, Noordwest Ziekenhuisgroep, Alkmaar and Dutch Network for Cardiovascular Research (WCN), the Netherlands; Department of Cardiology, CWZ Hospital, Nijmegen, the Netherland.

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http://dx.doi.org/10.1016/j.jacc.2017.11.050DOI Listing
February 2018

Prevention of Stroke with the Addition of Ezetimibe to Statin Therapy in Patients With Acute Coronary Syndrome in IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial).

Circulation 2017 Dec 30;136(25):2440-2450. Epub 2017 Sep 30.

TIMI Study Group, Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (E.A.B., S.D.W., R.P.G., J.-G.P., S.A.M., C.P.C., E.B.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.029095DOI Listing
December 2017

First experience with edoxaban and atrial fibrillation ablation - Insights from the ENGAGE AF-TIMI 48 trial.

Int J Cardiol 2017 Oct 2;244:192-195. Epub 2017 Jun 2.

TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, United States; Harvard Medical School, Boston, MA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.05.098DOI Listing
October 2017

Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease.

N Engl J Med 2017 05 17;376(18):1713-1722. Epub 2017 Mar 17.

From the Thrombolysis in Myocardial Infarction (TIMI) Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston (M.S.S., R.P.G., S.D.W., S.A.M., J.F.K.); Sydney Medical School, National Health and Medical Research Council Clinical Trials Centre, University of Sydney, Sydney (A.C.K.); Amgen, Thousand Oaks, CA (N.H., H.W., T.L., S.M.W.); International Centre for Circulatory Health, National Heart and Lung Institute, Imperial College London, London (P.S.S.); and Oslo University Hospital, Ullevål and Medical Faculty, University of Oslo, Oslo (T.R.P.).

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http://dx.doi.org/10.1056/NEJMoa1615664DOI Listing
May 2017

Rationale and design of REDUCE-IT: Reduction of Cardiovascular Events with Icosapent Ethyl-Intervention Trial.

Clin Cardiol 2017 Mar 15;40(3):138-148. Epub 2017 Mar 15.

Department of Medicine, Baylor College of Medicine, and Center for Cardiovascular Disease Prevention, Methodist DeBakey Heart and Vascular Center, Houston, Texas.

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http://dx.doi.org/10.1002/clc.22692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396348PMC
March 2017

Atherothrombotic Risk Stratification and Ezetimibe for Secondary Prevention.

J Am Coll Cardiol 2017 Feb;69(8):911-921

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2016.11.070DOI Listing
February 2017

Stroke and Mortality Risk in Patients With Various Patterns of Atrial Fibrillation: Results From the ENGAGE AF-TIMI 48 Trial (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48).

Circ Arrhythm Electrophysiol 2017 01;10(1)

From the Department of Medicine, UTSouthwestern Medical Center, Dallas, TX (M.S.L.); TIMI Study Group, Brigham and Women's Hospital, Boston, MA (R.P.G., C.T.R., B.M.S., A.E.C., S.A.M., E.M.A., E.B.); Department of Medicine, University of Oulu, Finland (H.H.); Oulu University Hospital, Finland (H.H.); Heart and Health Foundation of Turkey, Ankara (A.O.); Daiichi-Sankyo Pharma Development, Munich, Germany (H.L.); and Daiichi-Sankyo Pharma Development, Edison, NJ (M.F.M.).

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http://dx.doi.org/10.1161/CIRCEP.116.004267DOI Listing
January 2017

The benefit of adding ezetimibe to statin therapy in patients with prior coronary artery bypass graft surgery and acute coronary syndrome in the IMPROVE-IT trial.

Eur Heart J 2016 Dec 28;37(48):3576-3584. Epub 2016 Aug 28.

TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital and Harvard Medical School, 350 Longwood Avenue, 1st Floor Offices, Boston, MA 02115, USA

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https://academic.oup.com/eurheartj/article-lookup/doi/10.109
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http://dx.doi.org/10.1093/eurheartj/ehw377DOI Listing
December 2016

Cardiovascular Biomarker Score and Clinical Outcomes in Patients With Atrial Fibrillation: A Subanalysis of the ENGAGE AF-TIMI 48 Randomized Clinical Trial.

JAMA Cardiol 2016 Dec;1(9):999-1006

TIMI Study Group 2Cardiovascular Medicine Division, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamacardio.2016.3311DOI Listing
December 2016

Peripheral Revascularization in Patients With Peripheral Artery Disease With Vorapaxar: Insights From the TRA 2°P-TIMI 50 Trial.

JACC Cardiovasc Interv 2016 10;9(20):2157-2164

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jcin.2016.07.034DOI Listing
October 2016

Efficacy and safety of edoxaban compared with warfarin in patients with atrial fibrillation and heart failure: insights from ENGAGE AF-TIMI 48.

Eur J Heart Fail 2016 09 28;18(9):1153-61. Epub 2016 Jun 28.

TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital and Harvard Medical School, 350 Longwood Avenue, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1002/ejhf.595DOI Listing
September 2016

Edoxaban Versus Warfarin in Atrial Fibrillation Patients at Risk of Falling: ENGAGE AF-TIMI 48 Analysis.

J Am Coll Cardiol 2016 09;68(11):1169-1178

TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2016.06.034DOI Listing
September 2016

Outcomes With Edoxaban Versus Warfarin in Patients With Previous Cerebrovascular Events: Findings From ENGAGE AF-TIMI 48 (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48).

Stroke 2016 08 7;47(8):2075-82. Epub 2016 Jul 7.

From the Massachusetts General Hospital, Boston (N.S.R., S.S., A.B.S.); TIMI Study Group, Cardiovascular Medicine, Brigham and Women's Hospital, Boston MA (R.P.G., C.T.R., S.A.M., A.E.C., A.D.N., E.M.A., E.B.); Heart Institute (InCor), University of São Paulo Medical School, Brazil (J.C.N.); CARE Musheerabad, Hyderabad, India (B.S.); and Daiichi-Sankyo Pharma Development, Edison, NJ (M.F.M.).

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http://dx.doi.org/10.1161/STROKEAHA.116.013540DOI Listing
August 2016

Impact of Renal Function on Outcomes With Edoxaban in the ENGAGE AF-TIMI 48 Trial.

Circulation 2016 Jul;134(1):24-36

From the TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://circ.ahajournals.org/content/circulationaha/134/1/24.
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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.022361DOI Listing
July 2016

Universal Classification System Type of Incident Myocardial Infarction in Patients With Stable Atherosclerosis: Observations From Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events (TRA 2°P)-TIMI 50.

J Am Heart Assoc 2016 07 18;5(7). Epub 2016 Jul 18.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

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http://dx.doi.org/10.1161/JAHA.116.003237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015369PMC
July 2016

Atherothrombotic Risk Stratification and the Efficacy and Safety of Vorapaxar in Patients With Stable Ischemic Heart Disease and Previous Myocardial Infarction.

Circulation 2016 Jul;134(4):304-13

From the TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (E.A.B., M.P.B., E.B., P.H., S.A.M., M.S.S., B.M.S., D.A.M.); South Australian Health and Research Institute, Flinders University and Medical Centre, Adelaide (P.E.A.); Division of Cardiovascular Diseases, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago (R.C.); Department of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy (G.M.D.F.); Lady Davis Carmel Medical Center and the Ruth and Bruce Rappaport School of Medicine, Technion, Haifa, Israel (B.S.L.); and IV Divisione Cardiologia, Azienda Ospedaliera Niguarda Ca' Granda, Milan, Italy (P.A.M.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.019861DOI Listing
July 2016

Reduction in Ischemic Events With Ticagrelor in Diabetic Patients With Prior Myocardial Infarction in PEGASUS-TIMI 54.

J Am Coll Cardiol 2016 Jun 1;67(23):2732-2740. Epub 2016 Apr 1.

Département Hospitalo-Universitaire-Fibrosis, Inflammation, REmodelling, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, Université Paris-Diderot, Sorbonne-Paris Cité, and the French Alliance for Cardiovascular Clinical Trials, an F-CRIN network, INSERM U-1148, Paris, France.

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http://dx.doi.org/10.1016/j.jacc.2016.03.529DOI Listing
June 2016

Outcomes in Stable Patients With Previous Atherothrombotic Events Receiving Vorapaxar Who Experience a New Acute Coronary Event (from TRA2°P-TIMI 50).

Am J Cardiol 2016 Apr 14;117(7):1055-8. Epub 2016 Jan 14.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029149163000
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http://dx.doi.org/10.1016/j.amjcard.2015.12.052DOI Listing
April 2016

Acute Limb Ischemia and Outcomes With Vorapaxar in Patients With Peripheral Artery Disease: Results From the Trial to Assess the Effects of Vorapaxar in Preventing Heart Attack and Stroke in Patients With Atherosclerosis-Thrombolysis in Myocardial Infarction 50 (TRA2°P-TIMI 50).

Circulation 2016 Mar 29;133(10):997-1005. Epub 2016 Jan 29.

From TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA(M.P.B., J.A.G., B.M.S., S.A.H., E.B., D.A.M.); Dartmouth-Hitchcock Heart and Vascular Center, Geisel School of Medicine at Dartmouth, Lebanon, NH(M.A.C.); and Wiener Cardiovascular Institute and Marie-Jose and Henry R. Kravis Center for Cardiovascular Health, Mount Sinai School of Medicine, New York, NY (J.O.).

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http://circ.ahajournals.org/content/early/2016/01/29/CIRCULA
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http://circ.ahajournals.org/lookup/doi/10.1161/CIRCULATIONAH
Publisher Site
http://dx.doi.org/10.1161/CIRCULATIONAHA.115.019355DOI Listing
March 2016

Reduction in Total Cardiovascular Events With Ezetimibe/Simvastatin Post-Acute Coronary Syndrome: The IMPROVE-IT Trial.

J Am Coll Cardiol 2016 Feb;67(4):353-361

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2015.10.077DOI Listing
February 2016

Efficacy and Safety of Vorapaxar With and Without a Thienopyridine for Secondary Prevention in Patients With Previous Myocardial Infarction and No History of Stroke or Transient Ischemic Attack: Results from TRA 2°P-TIMI 50.

Circulation 2015 Nov 3;132(20):1871-9. Epub 2015 Sep 3.

From TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (E.A.B., M.P.B., S.A.M., B.M.S., E.B., D.A.M.); Department of Cardiovascular Medicine, Flinders Cardiovascular Center, Adelaide, Australia (P.E.A.); Cardiovascular Division, Pontificia Universidad Catolica de Chile, Santiago, Chile (R.L.C.); Department of Cardiology, Military Hospital, Budapest, Hungary (R.G.K.); and Green Lane Cardiovascular Research Unit, Auckland City Hospital, Auckland, New Zealand (H.W.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.015042DOI Listing
November 2015

The effect of rivaroxaban on myocardial infarction in the ATLAS ACS 2 - TIMI 51 trial.

Eur Heart J Acute Cardiovasc Care 2015 Oct 15;4(5):468-74. Epub 2014 Oct 15.

TIMI Study Group, Heart & Vascular Center, Brigham and Women's Hospital and Harvard Medical School, USA

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http://dx.doi.org/10.1177/2048872614554109DOI Listing
October 2015

Prognostic performance of a high-sensitivity assay for cardiac troponin I after non-ST elevation acute coronary syndrome: Analysis from MERLIN-TIMI 36.

Eur Heart J Acute Cardiovasc Care 2015 Oct 23;4(5):431-40. Epub 2014 Dec 23.

Department of Medicine, Brigham and Women's Hospital, Boston, USA.

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http://dx.doi.org/10.1177/2048872614564081DOI Listing
October 2015

On-Statin Resistin, Leptin, and Risk of Recurrent Coronary Events After Hospitalization for an Acute Coronary Syndrome (from the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 Study).

Am J Cardiol 2015 Sep 4;116(5):694-8. Epub 2015 Jun 4.

Department of Medicine and Cardiovascular Institute, Perelman School of Medicine, 11-125 Smillow Center for Translational Research, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1016/j.amjcard.2015.05.038DOI Listing
September 2015

Achievement of dual low-density lipoprotein cholesterol and high-sensitivity C-reactive protein targets more frequent with the addition of ezetimibe to simvastatin and associated with better outcomes in IMPROVE-IT.

Circulation 2015 Sep 1;132(13):1224-33. Epub 2015 Sep 1.

From TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (E.A.B., R.P.G., C.P.C., J.Z., S.A.M., E.B.); Duke Clinical Research Institute, Durham, NC (J.W., M.A.B.); and Merck, Kenilworth, NJ (A.M.T.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.018381DOI Listing
September 2015

Effects of Ranolazine in Patients With Chronic Angina in Patients With and Without Percutaneous Coronary Intervention for Acute Coronary Syndrome: Observations From the MERLIN-TIMI 36 Trial.

Clin Cardiol 2015 Aug 8;38(8):469-75. Epub 2015 Jun 8.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/clc.22425DOI Listing
August 2015

Edoxaban vs. warfarin in vitamin K antagonist experienced and naive patients with atrial fibrillation†.

Eur Heart J 2015 Jun 16;36(23):1470-7. Epub 2015 Feb 16.

TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, 350 Longwood Avenue, 1st Floor, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/eurheartj/ehv014DOI Listing
June 2015

Genetics and the clinical response to warfarin and edoxaban: findings from the randomised, double-blind ENGAGE AF-TIMI 48 trial.

Lancet 2015 Jun 11;385(9984):2280-7. Epub 2015 Mar 11.

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(14)61994-2DOI Listing
June 2015

Long-term use of ticagrelor in patients with prior myocardial infarction.

N Engl J Med 2015 May 14;372(19):1791-800. Epub 2015 Mar 14.

From the Thrombolysis in Myocardial Infarction (TIMI) Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston (M.P.B., D.L.B., G.M., M.P.F., K.I., S.A.M., S.D.W., E.B., M.S.S.); the Cardiovascular Division, Department of Medicine, Newark Beth Israel Medical Center, Rutgers-New Jersey Medical School, Newark (M.C.); French Alliance for Cardiovascular Trials, Département Hospitalo-Universitaire Fibrosis, Inflammation, Remodeling, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, INSERM Unité 1148, and Université Paris-Diderot, Sorbonne Paris Cité - all in Paris (P.G.S.); National Heart and Lung Institute, Royal Brompton Hospital, Imperial College, London (P.G.S.), and Department of Cardiovascular Science, University of Sheffield, Sheffield, United Kingdom (R.F.S.); AstraZeneca, Mölndal, Sweden (E.C.J., O.B., P.H.); Icahn School of Medicine at Mount Sinai, New York (S.B.); Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands (T.O.O.); Postgraduate Medical School, Grochowski Hospital, Warsaw, Poland (A.B.); Montreal Heart Institute, Université de Montréal, Montreal (P.T.); Cardiology Research Center, Moscow (M.R.); Kerckhoff Heart Center, Bad Nauheim, and University of Giessen, Giessen - both in Germany (C.H.); Department of Medicine (Cardiology), Tokai University School of Medicine, Isehara, Japan (S.G.); University Hospital, Jihlavska, Brno, Czech Republic (J.S.); Heart Institute (InCor)-University of São Paulo Medical School, São Paulo (J.C.N.); and the Department of Cardiology, Military Hospital, Budapest, Hungary (R.G.K.).

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http://dx.doi.org/10.1056/NEJMoa1500857DOI Listing
May 2015

Vorapaxar in patients with diabetes mellitus and previous myocardial infarction: findings from the thrombin receptor antagonist in secondary prevention of atherothrombotic ischemic events-TIMI 50 trial.

Circulation 2015 Mar 13;131(12):1047-53. Epub 2015 Feb 13.

From TIMI Study Group, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (M.A.C., B.M.S., M.P.B., S.A.M., E.B., D.A.M.); University of Florida College of Medicine, Jacksonville (D.J.A.); Milpark Hospital, Johannesburg, South Africa (A.J.D.); Sahlgrenska Academy, University of Gothenburg and Sahlgrenska University Hospital/Östra, Gothenburg, Sweden (M.D.); Santo Andre's Hospital, Leiria, Portugal (J.M.); Department of Cardiology, Canisius Wilhelmina Ziekenhuis, Nijmegen, The Netherlands (T.O.O.); and Third Division of Cardiology, Medical University of Silesia, Katowice, Poland (M.T.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.013774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365950PMC
March 2015

Efficacy and safety of vorapaxar as approved for clinical use in the United States.

J Am Heart Assoc 2015 Mar 19;4(3):e001505. Epub 2015 Mar 19.

TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (G.M., M.P.B., E.B., S.A.M., B.M.S., D.A.M.).

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http://dx.doi.org/10.1161/JAHA.114.001505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392433PMC
March 2015

Effect of ranolazine on atrial fibrillation in patients with non-ST elevation acute coronary syndromes: observations from the MERLIN-TIMI 36 trial.

Europace 2015 Jan 10;17(1):32-7. Epub 2014 Sep 10.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/europace/euu217DOI Listing
January 2015

Coronary stent thrombosis with vorapaxar versus placebo: results from the TRA 2° P-TIMI 50 trial.

J Am Coll Cardiol 2014 Dec 1;64(22):2309-17. Epub 2014 Dec 1.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2014.09.037DOI Listing
December 2014

New ischemic stroke and outcomes with vorapaxar versus placebo: results from the TRA 2 °P-TIMI 50 trial.

J Am Coll Cardiol 2014 Dec 1;64(22):2318-26. Epub 2014 Dec 1.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2014.07.997DOI Listing
December 2014

Cerebrovascular events in 21 105 patients with atrial fibrillation randomized to edoxaban versus warfarin: Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48.

Stroke 2014 Aug 19;45(8):2372-8. Epub 2014 Jun 19.

From the Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (R.P.G., C.T.R., S.D.W., C.L., N.D., S.A.M., L.T.G., E.M.A., E.B.); Department of Neurology, Massachusetts General Hospital, Boston (N.S.R., S.S.); Biostatistics, Quintiles, Inc, Durham, NC (J.M.B.); and Daiichi Sankyo, Inc, Pharma Development, Edison, NJ (A.D., J.D., M.S., M.M.).

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http://dx.doi.org/10.1161/STROKEAHA.114.006025DOI Listing
August 2014

Diagnostic performance of copeptin in patients with acute nontraumatic chest pain: BWH-TIMI ED chest pain study.

Clin Cardiol 2014 Apr 22;37(4):227-32. Epub 2014 Jan 22.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/clc.22244DOI Listing
April 2014

Prognostic performance of multiple biomarkers in patients with non-ST-segment elevation acute coronary syndrome: analysis from the MERLIN-TIMI 36 trial (Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST-Elevation Acute Coronary Syndromes-Thrombolysis In Myocardial Infarction 36).

J Am Coll Cardiol 2014 Apr 13;63(16):1644-53. Epub 2014 Feb 13.

TIMI Study Group, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2013.12.034DOI Listing
April 2014

Atrial fibrillation and prior MI: searching for balance in ischaemic and bleeding events in patients treated with factor-specific anticoagulants.

Eur Heart J 2014 Jan 25;35(4):207-8. Epub 2013 Nov 25.

TIMI Study Group, Brigham and Women's Hospital, 350 Longwood Ave, Boston, MA 01760, USA.

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http://dx.doi.org/10.1093/eurheartj/eht480DOI Listing
January 2014

Evaluation of the diagnostic performance of heart-type fatty acid binding protein in the BWH-TIMI ED chest pain study.

J Thromb Thrombolysis 2013 Nov;36(4):361-7

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 350 Longwood Avenue, 1st Floor Offices, Boston, MA, 02115, USA,

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http://dx.doi.org/10.1007/s11239-013-0870-7DOI Listing
November 2013

Edoxaban versus warfarin in patients with atrial fibrillation.

N Engl J Med 2013 Nov 19;369(22):2093-104. Epub 2013 Nov 19.

From Brigham and Women's Hospital and Harvard Medical School, Boston (R.P.G., C.T.R., E.B., S.A.M., S.D.W., L.T.G., E.M.A.); Mount Sinai Medical Center, New York (J.L.H.); University Hospitals Case Medical Center, Cleveland (A.L.W.); Thomas Jefferson Medical College, Philadelphia (M.D.E.); McMaster University, Hamilton, ON, Canada (J.I.W.); University Hospital, Jihlavska, Brno, Czech Republic (J.S.); Institute of Cardiology, Warsaw, Poland (W.R.); Cardiology Research Center, Moscow (M.R.); National Hospital Organization, Osaka National Hospital, Osaka, Japan (Y.K.); Quintiles, Durham, NC (J.B., S.P.P.); and Daiichi Sankyo Pharma Development, Edison, NJ (M.S., I.P., J.J.H., M.M.).

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http://dx.doi.org/10.1056/NEJMoa1310907DOI Listing
November 2013

Urinary albumin concentration and long-term cardiovascular risk in acute coronary syndrome patients: a PROVE IT-TIMI 22 substudy.

J Thromb Thrombolysis 2013 Oct;36(3):233-9

Division of Cardiology, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1007/s11239-012-0853-0DOI Listing
October 2013

Comparison of the efficacy and safety of two rivaroxaban doses in acute coronary syndrome (from ATLAS ACS 2-TIMI 51).

Am J Cardiol 2013 Aug 24;112(4):472-8. Epub 2013 May 24.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.amjcard.2013.04.011DOI Listing
August 2013

When 'digoxin use' is not the same as 'digoxin use': lessons from the AFFIRM trial.

Authors:
Sabina A Murphy

Eur Heart J 2013 May 16;34(20):1465-7. Epub 2013 Apr 16.

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http://dx.doi.org/10.1093/eurheartj/eht087DOI Listing
May 2013

Prognostic evaluation of catalytic iron in patients with acute coronary syndromes.

Clin Cardiol 2013 Mar 3;36(3):139-45. Epub 2013 Feb 3.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1002/clc.22089DOI Listing
March 2013

Vorapaxar in the secondary prevention of atherothrombotic events.

N Engl J Med 2012 Apr 24;366(15):1404-13. Epub 2012 Mar 24.

Thrombolysis in Myocardial Infarction (TIMI) Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://www.nejm.org/doi/abs/10.1056/NEJMoa1200933
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http://dx.doi.org/10.1056/NEJMoa1200933DOI Listing
April 2012