Saar Gill

Division of Hematology Oncology, Abramson Cancer Center, Cell Therapy and Transplant, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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February 2020

How close are we to CAR T-cell therapy for AML?

Authors:

Saar I Gill

Best Pract Res Clin Haematol 2019 12 18;32(4):101104. Epub 2019 Oct 18.

University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA, 19104, USA. Electronic address:

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December 2019

A cellular antidote to specifically deplete anti-CD19 chimeric antigen receptor-positive cells.

Authors:

Marco Ruella David M Barrett Olga Shestova Jessica Perazzelli Avery D Posey Seok Jae Hong Miroslaw Kozlowski Simon F Lacey J Joseph Melenhorst Carl H June Saar I Gill

Blood 2020 02;135(7):505-509

Center for Cellular Immunotherapies and.

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February 2020

Chimeric antigen receptor T-cell therapy for acute myeloid leukemia: how close to reality?

Authors:

Katherine D Cummins Saar Gill

Haematologica 2019 07 20;104(7):1302-1308. Epub 2019 Jun 20.

Division of Hematology-Oncology and Center for Cellular Immunotherapies, University of Pennsylvania, PA, USA

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July 2019

Clinical utilization of Chimeric Antigen Receptor T-cells (CAR-T) in B-cell acute lymphoblastic leukemia (ALL)-an expert opinion from the European Society for Blood and Marrow Transplantation (EBMT) and the American Society for Blood and Marrow Transplantation (ASBMT).

Bone Marrow Transplant 2019 11 15;54(11):1868-1880. Epub 2019 May 15.

Division of Hematology, Ohio State University Wexner Medical Center, Columbus, OH, USA.

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November 2019

Will CAR T cell therapy have a role in AML? Promises and pitfalls.

Authors:

Katherine D Cummins Saar Gill

Semin Hematol 2019 04 29;56(2):155-163. Epub 2018 Aug 29.

Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA; Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania, Center for Cellular Immunotherapies, The University of Pennsylvania, Philadelphia, PA. Electronic address:

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April 2019

Bispecific Antibodies in the Treatment of Hematologic Malignancies.

Authors:

Johannes Duell Philip E Lammers Ivana Djuretic Allison G Chunyk Shilpa Alekar Ira Jacobs Saar Gill

Clin Pharmacol Ther 2019 10 29;106(4):781-791. Epub 2019 Mar 29.

Blood and Marrow Transplantation Program, Abramson Cancer Center and the Division of Hematology and Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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October 2019

21 Century FOX: Toward Gene Therapy for the Regulatory T Cell Deficiency Syndrome IPEX.

Authors:

Nicholas E Petty Saar I Gill

Cell Stem Cell 2019 02;24(2):208-209

Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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February 2019

Clinical Utilization of Chimeric Antigen Receptor T Cells in B Cell Acute Lymphoblastic Leukemia: An Expert Opinion from the European Society for Blood and Marrow Transplantation and the American Society for Blood and Marrow Transplantation.

Biol Blood Marrow Transplant 2019 03 18;25(3):e76-e85. Epub 2018 Dec 18.

Oncology Centre, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, Minnesota. Electronic address:

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March 2019

Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell.

Nat Med 2018 10 1;24(10):1499-1503. Epub 2018 Oct 1.

Center for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

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October 2018

Oral Vancomycin Prophylaxis Is Highly Effective in Preventing Clostridium difficile Infection in Allogeneic Hematopoietic Cell Transplant Recipients.

Authors:

Alex Ganetsky Jennifer H Han Mitchell E Hughes Daria V Babushok Noelle V Frey Saar I Gill Elizabeth O Hexner Alison W Loren Selina M Luger James K Mangan Mary Ellen Martin Jacqueline Smith Craig W Freyer Cheryl Gilmar Mindy Schuster Edward A Stadtmauer David L Porter

Clin Infect Dis 2019 05;68(12):2003-2009

Blood and Marrow Transplantation Program, Abramson Cancer Center and the Division of Hematology and Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.

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May 2019

Nonviral RNA chimeric antigen receptor-modified T cells in patients with Hodgkin lymphoma.

Authors:

Jakub Svoboda Susan R Rheingold Saar I Gill Stephan A Grupp Simon F Lacey Irina Kulikovskaya Megan M Suhoski J Joseph Melenhorst Brandon Loudon Anthony R Mato Sunita Dwivedy Nasta Daniel J Landsburg Matthew R Youngman Bruce L Levine David L Porter Carl H June Stephen J Schuster

Blood 2018 09 20;132(10):1022-1026. Epub 2018 Jun 20.

Lymphoma Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA.

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September 2018

Novel Approaches to Acute Myeloid Leukemia Immunotherapy.

Authors:

Ofrat Beyar-Katz Saar Gill

Clin Cancer Res 2018 11 14;24(22):5502-5515. Epub 2018 Jun 14.

Division of Hematology-Oncology and Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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November 2018

Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia.

Cell 2018 05 31;173(6):1439-1453.e19. Epub 2018 May 31.

Center for Cellular Immunotherapies, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA; Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. Electronic address:

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May 2018

Tocilizumab for the treatment of severe steroid-refractory acute graft-versus-host disease of the lower gastrointestinal tract.

Authors:

Alex Ganetsky Noelle V Frey Elizabeth O Hexner Alison W Loren Saar I Gill Selina M Luger James K Mangan Mary Ellen Martin Daria V Babushok William R Drobyski Jacqueline Smith Colleen Timlin Craig W Freyer Edward A Stadtmauer David L Porter

Bone Marrow Transplant 2019 02 24;54(2):212-217. Epub 2018 May 24.

Blood and Marrow Transplantation Program, Abramson Cancer Center and the Division of Hematology and Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

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February 2019

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:

Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 Apr;24(4):526

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April 2018

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