Saad Shakir

Saad Shakir

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Saad Shakir

Publications by authors named "Saad Shakir"

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First Conference on Big Data for Pharmacovigilance.

Drug Saf 2018 12;41(12):1281-1284

Drug Safety Research Unit, Southampton, UK.

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http://dx.doi.org/10.1007/s40264-018-0727-2DOI Listing
December 2018

Safety of Atrovent CFC-free inhaler: respiratory events reported from an observational cohort study in England.

Int J Pharm Pract 2018 Aug 9;26(4):356-363. Epub 2017 Oct 9.

Drug Safety Research Unit, Southampton, UK.

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http://dx.doi.org/10.1111/ijpp.12407DOI Listing
August 2018

Utilisation and Safety of Deferasirox: Results from an Observational Cohort Study in England.

Drug Saf 2018 03;41(3):267-275

Drug Safety Research Unit, Bursledon Hall, Blundell Lane, Southampton, SO31 1AA, UK.

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http://dx.doi.org/10.1007/s40264-017-0606-2DOI Listing
March 2018

The 9th Biennial Conference on Signal Detection and Interpretation in Pharmacovigilance.

Drug Saf 2018 Jan;41(1):139-141

Drug Safety Research Unit, Southampton, UK.

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http://link.springer.com/10.1007/s40264-017-0587-1
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http://dx.doi.org/10.1007/s40264-017-0587-1DOI Listing
January 2018

Drugs and life-threatening ventricular arrhythmia risk: results from the DARE study cohort.

BMJ Open 2017 Oct 16;7(10):e016627. Epub 2017 Oct 16.

Research Department, Drug Safety Research Unit, Southampton, UK.

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http://dx.doi.org/10.1136/bmjopen-2017-016627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652462PMC
October 2017

Utilisation and Tolerability of Aliskiren in the Primary Care Setting in England.

J Clin Hypertens (Greenwich) 2016 12 3;18(12):1237-1243. Epub 2016 Jun 3.

Drug Safety Research Unit, Southampton, UK.

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http://dx.doi.org/10.1111/jch.12852DOI Listing
December 2016

Pattern of Onset and Risk Factors for Peripheral Oedema During Vildagliptin Use: Analysis from the Vildagliptin Prescription-Event Monitoring Study in England.

Drug Saf 2016 11;39(11):1093-1104

Drug Safety Research Unit, Bursledon Hall, Blundell Lane, Southampton, SO31 1AA, UK.

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http://dx.doi.org/10.1007/s40264-016-0451-8DOI Listing
November 2016

Specialist Cohort Event Monitoring studies: a new study method for risk management in pharmacovigilance.

Drug Saf 2015 Feb;38(2):153-63

Drug Safety Research Unit, Bursledon Hall, Blundell Lane, Southampton, SO31 1AA, UK,

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http://dx.doi.org/10.1007/s40264-014-0260-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4328122PMC
February 2015

Implications of off-label use: An example from the final results of an observational cohort study on Intrinsa® (testosterone patch).

Post Reprod Health 2014 Jun 12;20(2):48-54. Epub 2014 May 12.

Drug Safety Research Unit, Bursledon Hall, Southampton, UK School of Pharmacy and Biomedical Science, University of Portsmouth, Portsmouth, UK.

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http://dx.doi.org/10.1177/2053369114535762DOI Listing
June 2014

How do patients contribute to signal detection? : A retrospective analysis of spontaneous reporting of adverse drug reactions in the UK's Yellow Card Scheme.

Drug Saf 2013 Mar;36(3):199-206

Drug Safety Research Unit, Bursledon Hall, Blundell Lane, Bursledon, Southampton, SO31 1AA, UK.

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http://dx.doi.org/10.1007/s40264-013-0021-2DOI Listing
March 2013

Modified prescription-event monitoring studies: a tool for pharmacovigilance and risk management.

Drug Saf 2011 Dec;34(12):e1-9

Drug Safety Research Unit, Bursledon Hall, Blundell Lane, Southampton, UK.

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http://dx.doi.org/10.2165/11593830-000000000-00000DOI Listing
December 2011

Paediatric post-marketing pharmacovigilance: comparison of the adverse event profile of vigabatrin prescribed to children and adults.

Pharmacoepidemiol Drug Saf 2011 Jun 23;20(6):608-18. Epub 2011 Feb 23.

Drug Safety Reseach Unit, Department of Drug Safety, Bursledon Hall, Blundell Lane, Southampton, UK.

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http://dx.doi.org/10.1002/pds.2105DOI Listing
June 2011

New postgraduate qualifications in pharmacovigilance from the Drug Safety Research Unit in the UK.

Drug Saf 2011 Jan;34(1):89-91

Drug Safety Research Unit, Bursledon Hall, Southampton, UK.

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http://dx.doi.org/10.2165/11586810-000000000-00000DOI Listing
January 2011

Hypoglycaemia with pioglitazone: analysis of data from the Prescription-Event Monitoring study.

J Eval Clin Pract 2010 Dec;16(6):1124-8

Department of Social and Clinical Pharmacy, Faculty of Pharmacy, Charles University in Prague, Hradec Kralove, Czech Republic.

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http://dx.doi.org/10.1111/j.1365-2753.2009.01280.xDOI Listing
December 2010

Safety profile of oxcarbazepine: results from a prescription-event monitoring study.

Epilepsia 2010 May 3;51(5):818-29. Epub 2010 Feb 3.

Drug Safety Research Unit, Southampton, United Kingdom.

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http://dx.doi.org/10.1111/j.1528-1167.2009.02489.xDOI Listing
May 2010

Risk management and outcomes of adverse events to pioglitazone in primary care in the UK: an observational study.

Drug Saf 2009 ;32(3):229-37

Drug Safety Research Unit, Bursledon Hall, Southampton, UK.

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http://dx.doi.org/10.2165/00002018-200932030-00005DOI Listing
June 2009

Monitoring the safety of pioglitazone : results of a prescription-event monitoring study of 12,772 patients in England.

Drug Saf 2008 ;31(10):839-50

Drug Safety Research Unit, Southampton, United Kingdom.

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http://dx.doi.org/10.2165/00002018-200831100-00003DOI Listing
January 2009

Prescriber adoption of newly approved selective COX-2 inhibitors.

Pharmacoepidemiol Drug Saf 2008 Dec;17(12):1168-74

Drug Safety Research Unit, Bursledon Hall, Blundell Lane, Southampton, UK.

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http://dx.doi.org/10.1002/pds.1667DOI Listing
December 2008

The safety profiles of orlistat and sibutramine: results of prescription-event monitoring studies in England.

Obesity (Silver Spring) 2007 Nov;15(11):2712-22

Drug Safety Research Unit, Bursledon Hall, Blundell Lane, Southampton, United Kingdom S031 1AA.

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http://dx.doi.org/10.1038/oby.2007.323DOI Listing
November 2007

Thoughts on signal detection in pharmacovigilance.

Authors:
Saad A W Shakir

Drug Saf 2007 ;30(7):603-6

Drug Safety Research Unit, Southampton, UK.

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http://dx.doi.org/10.2165/00002018-200730070-00005DOI Listing
September 2007

The safety of quetiapine: results of a post-marketing surveillance study on 1728 patients in England.

J Psychopharmacol 2007 Jun;21(4):392-9

Drug Safety Research Unit, Southampton, UK.

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http://dx.doi.org/10.1177/0269881107073257DOI Listing
June 2007

An analysis of the exclusion criteria used in observational pharmacoepidemiological studies.

Pharmacoepidemiol Drug Saf 2007 Mar;16(3):329-36

Drug Safety Research Unit, Southampton, UK.

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http://dx.doi.org/10.1002/pds.1262DOI Listing
March 2007

Bill Inman: drug safety physician and pharmacoepidemiologist.

Authors:
Saad A W Shakir

Drug Saf 2006 ;29(3):187-8

Drug Safety Research Unit, Southampton, UK.

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http://dx.doi.org/10.2165/00002018-200629030-00002DOI Listing
January 2007

Under-reporting of adverse drug reactions : a systematic review.

Drug Saf 2006 ;29(5):385-96

Drug Safety Research Unit, Southampton, UK.

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http://link.springer.com/10.2165/00002018-200629050-00003
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http://dx.doi.org/10.2165/00002018-200629050-00003DOI Listing
October 2006

Exposure to mirtazapine during pregnancy: a prospective, comparative study of birth outcomes.

J Clin Psychiatry 2006 Aug;67(8):1280-4

Motherisk Program, Division of Clinical Pharmacology, the Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.4088/jcp.v67n0817DOI Listing
August 2006

Prescription-event monitoring study on 13,164 patients prescribed risedronate in primary care in England.

Osteoporos Int 2005 Dec 31;16(12):1989-98. Epub 2005 Aug 31.

Drug Safety Research Unit, Bursledon Hall, Blundell Lane, Southampton, UK.

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http://dx.doi.org/10.1007/s00198-005-1986-1DOI Listing
December 2005

Deep vein thrombosis and pulmonary embolism reported in the Prescription Event Monitoring Study of Yasmin.

Br J Clin Pharmacol 2005 Jul;60(1):98-102

Drug Safety Research Unit, Bursledon Hall, Blundell Lane, Southampton, UK.

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http://dx.doi.org/10.1111/j.1365-2125.2005.02373.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884900PMC
July 2005

Safety profile of raloxifene as used in general practice in England: results of a prescription-event monitoring study.

Osteoporos Int 2005 May 7;16(5):490-500. Epub 2004 Aug 7.

Drug Safety Research Unit, Bursledon Hall, Blundell Lane, Southampton, UK.

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http://dx.doi.org/10.1007/s00198-004-1710-6DOI Listing
May 2005

The safety and effectiveness of newer antiepileptics: a comparative postmarketing cohort study.

J Clin Pharmacol 2005 Apr;45(4):385-93

MRCP, Drug Safety Research Unit, Blundell Lane, Southampton SO31 1AA, UK.

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http://dx.doi.org/10.1177/0091270004273678DOI Listing
April 2005

Pregnancy outcome of women using atypical antipsychotic drugs: a prospective comparative study.

J Clin Psychiatry 2005 Apr;66(4):444-9; quiz 546

Motherisk Program, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.4088/jcp.v66n0406DOI Listing
April 2005

Pregnancy outcome of women exposed to bupropion during pregnancy: a prospective comparative study.

Am J Obstet Gynecol 2005 Mar;192(3):932-6

The Motherisk Program, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.ajog.2004.09.027DOI Listing
March 2005

Safety profile of celecoxib as used in general practice in England: results of a prescription-event monitoring study.

Eur J Clin Pharmacol 2004 Sep;60(7):489-501

Drug Safety Research Unit, Bursledon Hall, Blundell Lane, Southampton, SO31 1AA, UK.

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http://dx.doi.org/10.1007/s00228-004-0788-2DOI Listing
September 2004

Do some inhibitors of COX-2 increase the risk of thromboembolic events?: Linking pharmacology with pharmacoepidemiology.

Drug Saf 2004 ;27(7):427-56

New Zealand Pharmacovigilance Centre, Department of Preventive and Social Medicine, School of Medicine & Department of Pharmacology and Toxicology, School of Medical Sciences, University of Otago, Dunedin, New Zealand.

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http://dx.doi.org/10.2165/00002018-200427070-00002DOI Listing
August 2004

Evaluation of the safety of bupropion (Zyban) for smoking cessation from experience gained in general practice use in England in 2000.

Eur J Clin Pharmacol 2003 Dec 13;59(10):767-73. Epub 2003 Nov 13.

Drug Safety Research Unit, Southampton, UK.

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http://dx.doi.org/10.1007/s00228-003-0693-0DOI Listing
December 2003

Comparison of the incidence rates of thromboembolic events reported for patients prescribed celecoxib and meloxicam in general practice in England using Prescription-Event Monitoring (PEM) data.

Rheumatology (Oxford) 2003 Nov 16;42(11):1354-64. Epub 2003 Jul 16.

Drug Safety Research Unit, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1093/rheumatology/keg401DOI Listing
November 2003

Relative risk of vaginal candidiasis after use of antibiotics compared with antidepressants in women: postmarketing surveillance data in England.

Drug Saf 2003 ;26(8):589-97

Drug Safety Research Unit, Southampton, United KingdomUniversity of Portsmouth, Portsmouth, United Kingdom.

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http://dx.doi.org/10.2165/00002018-200326080-00005DOI Listing
September 2003

Pharmacovigilance study of alendronate in England.

Osteoporos Int 2003 Jul 23;14(6):507-14. Epub 2003 Apr 23.

Drug Safety Research Unit, Bursledon Hall, Blundell Lane, SO31 1AA, Southampton, UK.

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http://dx.doi.org/10.1007/s00198-003-1399-yDOI Listing
July 2003

Prolongation of the QT interval and cardiac arrhythmias associated with cisapride: limitations of the pharmacoepidemiological studies conducted and proposals for the future.

Pharmacoepidemiol Drug Saf 2003 Jan-Feb;12(1):31-40

Drug Safety Research Unit, Bursledon Hall, Blundell Lane, Southampton SO31 1AA, UK.

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http://dx.doi.org/10.1002/pds.781DOI Listing
June 2003

The pharmacovigilance of pantoprazole: the results of postmarketing surveillance on 11 541 patients in England.

Drug Saf 2003 ;26(2):121-32

Drug Safety Research Unit, Bursledon Hall, Southampton, United Kingdom.

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http://dx.doi.org/10.2165/00002018-200326020-00005DOI Listing
March 2003

The pharmacovigilance of mirtazapine: results of a prescription event monitoring study on 13554 patients in England.

J Psychopharmacol 2003 Mar;17(1):121-6

Drug Safety Research Unit, Bursledon Hall, Southampton, London, UK.

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http://dx.doi.org/10.1177/0269881103017001716DOI Listing
March 2003

Automated signal generation in prescription-event monitoring.

Drug Saf 2002 ;25(6):423-32

Drug Safety Research Unit, Bursledon Hall, Southampton, United Kingdom.

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http://dx.doi.org/10.2165/00002018-200225060-00006DOI Listing
September 2002

Causal association in pharmacovigilance and pharmacoepidemiology: thoughts on the application of the Austin Bradford-Hill criteria.

Drug Saf 2002 ;25(6):467-71

Drug Safety Research Unit, Bursledon Hall, Southampton, United Kingdom.

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http://dx.doi.org/10.2165/00002018-200225060-00012DOI Listing
September 2002

A postmarketing surveillance study of gabapentin as add-on therapy for 3,100 patients in England.

Epilepsia 2002 Sep;43(9):983-92

Drug Safety Research Unit, Southampton, England.

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http://dx.doi.org/10.1046/j.1528-1157.2002.01702.xDOI Listing
September 2002

A post-marketing surveillance study of formoterol (Foradil): its use in general practice in England.

Drug Saf 2002 ;25(3):213-23

Drug Safety Research Unit, Bursledon Hall, Bursledon, Southampton, United Kingdom.

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http://dx.doi.org/10.2165/00002018-200225030-00006DOI Listing
June 2002

Results of a postal survey of the reasons for non-response by doctors in a Prescription Event Monitoring study of drug safety.

Pharmacoepidemiol Drug Saf 2002 Mar;11(2):143-8

Drug Safety Research Unit, Burseldon Hall, Southampton SO31 1AA, UK.

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http://dx.doi.org/10.1002/pds.690DOI Listing
March 2002