Ryuji Higashikubo

Ryuji Higashikubo

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Ryuji Higashikubo

Ryuji Higashikubo

Publications by authors named "Ryuji Higashikubo"

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Selective targeting of IL-2 to NKG2D bearing cells for improved immunotherapy.

Nat Commun 2016 09 21;7:12878. Epub 2016 Sep 21.

Department of Surgery, Washington University in St Louis, 660 South Euclid Avenue, St Louis, Missouri 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036003PMC
http://dx.doi.org/10.1038/ncomms12878DOI Listing
September 2016

Deficiency of the adaptor protein SLy1 results in a natural killer cell ribosomopathy affecting tumor clearance.

Oncoimmunology 2016 27;5(12):e1238543. Epub 2016 Sep 27.

Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA; The Alvin Siteman Cancer Center of Washington University School of Medicine, St. Louis, MO, USA; The John Cochran VA Medical Center, St. Louis, MO, USA.

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http://dx.doi.org/10.1080/2162402X.2016.1238543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215235PMC
September 2016

Quantitative receptor-based imaging of tumor proliferation with the sigma-2 ligand [(18)F]ISO-1.

PLoS One 2013 20;8(9):e74188. Epub 2013 Sep 20.

Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, United States of America ; Department of Biomedical Engineering, Washington University School of Medicine, St. Louis, Missouri, United States of America ; Division of Biology and Biomedical Sciences, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0074188PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779213PMC
May 2014

Unique pulmonary antigen presentation may call for an alternative approach toward lung cancer immunotherapy.

Oncoimmunology 2013 Mar;2(3):e23563

Department of Surgery, Division of Cardiothoracic Surgery, Alvin Siteman Cancer Center and Department of Pathology and Immunology Washington University School of Medicine.

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http://dx.doi.org/10.4161/onci.23563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661173PMC
March 2013

Mild hyperthermia as a potential mechanism to locally enhance cell growth kinetics.

J Drug Target 2009 Nov;17(9):719-23

College of Pharmacy, Nova Southeastern University, Ft. Lauderdale, FL 33328, USA.

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http://dx.doi.org/10.3109/10611860903074968DOI Listing
November 2009

Phosphorylation-dependent Lys63-linked polyubiquitination of Daxx is essential for sustained TNF-{alpha}-induced ASK1 activation.

Cancer Res 2009 Oct 29;69(19):7512-7. Epub 2009 Sep 29.

Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-09-2148DOI Listing
October 2009

Tissue transgluaminase 2 expression in meningiomas.

J Neurooncol 2008 Nov 28;90(2):125-32. Epub 2008 Jun 28.

Department of Neurological Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Box 8057, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1007/s11060-008-9642-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732188PMC
November 2008

Use of multiple carboxylates to increase intracellular retention of fluorescent probes following release from cell penetrating fluorogenic conjugates.

Bioconjug Chem 2008 Jan 20;19(1):50-6. Epub 2007 Nov 20.

Chemistry Department, Washington University, St. Louis, Missouri 63130, USA.

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http://dx.doi.org/10.1021/bc070079yDOI Listing
January 2008

Characterization of somatostatin receptor subtype 2 expression in stably transfected A-427 human cancer cells.

Mol Imaging 2007 Jan-Feb;6(1):56-67

Department of Radiation Oncology and Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63108, USA.

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December 2007

Comparison of molecular markers of hypoxia and imaging with (60)Cu-ATSM in cancer of the uterine cervix.

Mol Imaging Biol 2007 Sep-Oct;9(5):278-83

Department of Radiation Oncology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://link.springer.com/content/pdf/10.1007/s11307-007-0095
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http://link.springer.com/10.1007/s11307-007-0095-2
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http://dx.doi.org/10.1007/s11307-007-0095-2DOI Listing
October 2007

The in vivo antitumoral effects of lipopolysaccharide against glioblastoma multiforme are mediated in part by Toll-like receptor 4.

Neurosurgery 2007 Feb;60(2):372-80; discussion 381

Department of Neurosurgery, Washington University School of Medicine, Saint Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1227/01.NEU.0000249280.61761.2EDOI Listing
February 2007

Novel chemical enhancers of heat shock increase thermal radiosensitization through a mitotic catastrophe pathway.

Cancer Res 2007 Jan;67(2):695-701

Department of Radiation Oncology/Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA, and Princess Margaret Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3212DOI Listing
January 2007

Tissue transglutaminase 2 inhibition promotes cell death and chemosensitivity in glioblastomas.

Mol Cancer Ther 2005 Sep;4(9):1293-302

Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-04-0328DOI Listing
September 2005

Retinamide-induced apoptosis in glioblastomas is associated with down-regulation of Bcl-xL and Bcl-2 proteins.

J Neurooncol 2005 Sep;74(3):225-32

Department of Neurological Surgery, Washington University School of Medicine, 660 South Euclid Avenue, 8057, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1007/s11060-005-7305-zDOI Listing
September 2005

Combined inhibition of extracellular signal-regulated kinases and HSP90 sensitizes human colon carcinoma cells to ionizing radiation.

Oncogene 2005 Apr;24(18):3011-9

Department of Radiation Oncology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63108, USA.

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http://www.nature.com/articles/1208508
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http://dx.doi.org/10.1038/sj.onc.1208508DOI Listing
April 2005

Mitochondrial O2*- and H2O2 mediate glucose deprivation-induced stress in human cancer cells.

J Biol Chem 2005 Feb 23;280(6):4254-63. Epub 2004 Nov 23.

Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1074/jbc.M411662200DOI Listing
February 2005

A comparative analysis of alphaA- and alphaB-crystallin expression during the cell cycle in primary mouse lens epithelial cultures.

Exp Eye Res 2004 Dec;79(6):795-805

Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8096, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.exer.2004.05.006DOI Listing
December 2004

Evaluation of parameters of oxidative stress after in vitro exposure to FMCW- and CDMA-modulated radiofrequency radiation fields.

Radiat Res 2004 Nov;162(5):497-504

Department of Radiation Oncology, Washington University, St. Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1667/rr3251DOI Listing
November 2004

Cell kinetic status of mouse lens epithelial cells lacking alphaA- and alphaB-crystallin.

Mol Cell Biochem 2004 Oct;265(1-2):115-22

Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8096, St. Louis, MO 63110, U.S.A.

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http://dx.doi.org/10.1023/b:mcbi.0000044365.48900.82DOI Listing
October 2004

HSP70 and genomic stability.

Cell Cycle 2004 May 15;3(5):591-2. Epub 2004 May 15.

Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri 63108, USA.

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http://dx.doi.org/10.4161/cc.3.5.863DOI Listing
May 2004

Lovastatin-induced up-regulation of the BH3-only protein, Bim, and cell death in glioblastoma cells.

J Neurochem 2004 Apr;89(1):168-78

Department of Neurological Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA.

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http://doi.wiley.com/10.1111/j.1471-4159.2004.02319.x
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http://dx.doi.org/10.1111/j.1471-4159.2004.02319.xDOI Listing
April 2004

Measurement of DNA damage and apoptosis in Molt-4 cells after in vitro exposure to radiofrequency radiation.

Radiat Res 2004 Feb;161(2):193-200

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Mallinckrodt Institute of Radiology, Washington University, St. Louis, MO 63108, USA.

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http://dx.doi.org/10.1667/rr3127DOI Listing
February 2004

Redox regulation of the G1 to S phase transition in the mouse embryo fibroblast cell cycle.

Cancer Res 2003 May;63(9):2109-17

Free Radical and Radiation Biology Program, Department of Radiation Oncology, University of Iowa, Iowa City 52242, USA.

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May 2003

Evidence that protein disulfide isomerase (PDI) is involved in DNA-nuclear matrix anchoring.

J Cell Biochem 2002 ;85(4):689-702

Washington University School of Medicine, Division of Radiation and Cancer Biology, Department of Radiation Oncology, St. Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1002/jcb.10169DOI Listing
October 2002

Redox control of cell cycle-coupled topoisomerase II alpha gene expression.

Methods Enzymol 2002 ;353:448-59

Free Radical and Radiation Biology Program, University of Iowa, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1016/s0076-6879(02)53068-8DOI Listing
August 2002