Publications by authors named "Ryo Goitsuka"

38Publications

Transcription factor Tlx1 marks a subset of lymphoid tissue organizer-like mesenchymal progenitor cells in the neonatal spleen.

Sci Rep 2019 12 31;9(1):20408. Epub 2019 Dec 31.

Division of Development and Aging, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.

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December 2019

Nuclear localization of Meis1 in dermal papilla promotes hair matrix cell proliferation in the anagen phase of hair cycle.

Biochem Biophys Res Commun 2019 11 19;519(4):727-733. Epub 2019 Sep 19.

Division of Development and Aging, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan; Imaging Frontier Center, Tokyo University of Science, Chiba, Japan. Electronic address:

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November 2019

High-affinity IgM memory B cells are defective in differentiation into IgM antibody-secreting cells by re-stimulation with a T cell-dependent antigen.

Sci Rep 2018 09 28;8(1):14559. Epub 2018 Sep 28.

Division of Biosignaling, Research Institute for Biomedical Sciences, Tokyo University of Science, Noda, Chiba, Japan.

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September 2018

Niche-induced extramedullary hematopoiesis in the spleen is regulated by the transcription factor Tlx1.

Sci Rep 2018 05 29;8(1):8308. Epub 2018 May 29.

Division of Development and Aging, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.

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May 2018

Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation.

J Neurosci 2018 01 9;38(5):1277-1294. Epub 2018 Jan 9.

Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo 187-8502, Japan,

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January 2018

Germ cell-intrinsic requirement for the homeodomain transcription factor PKnox1/Prep1 in adult spermatogenesis.

PLoS One 2018 2;13(1):e0190702. Epub 2018 Jan 2.

Division of Development and Aging, Research Institute for Biomedical Sciences, Tokyo University of Science, Noda, Chiba, Japan.

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February 2018

Loss of the Homeodomain Transcription Factor Prep1 Perturbs Adult Hematopoiesis in the Bone Marrow.

PLoS One 2015 18;10(8):e0136107. Epub 2015 Aug 18.

Division of Development and Aging, Research Institute for Biomedical Sciences, Tokyo University of Science, Noda, Chiba, Japan.

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May 2016

Generation of a Tlx1(CreER-Venus) knock-in mouse strain for the study of spleen development.

Genesis 2014 Nov 18;52(11):916-23. Epub 2014 Oct 18.

Division of Development and Aging, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.

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November 2014

Promotion of crystalline cellulose degradation by expansins from Oryza sativa.

Planta 2015 Jan 14;241(1):83-93. Epub 2014 Sep 14.

Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda-shi, Chiba-Ken, 278-8510, Japan,

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January 2015

Meis1 regulates epidermal stem cells and is required for skin tumorigenesis.

PLoS One 2014 11;9(7):e102111. Epub 2014 Jul 11.

Department of Carcinogenesis Research, Division of Experimental Animal Research, Chiba Cancer Center Research Institute, Chiba, Chiba, Japan.

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March 2015

Meis1 is required for the maintenance of postnatal thymic epithelial cells.

PLoS One 2014 4;9(3):e89885. Epub 2014 Mar 4.

Division of Development and Aging, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.

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February 2015

Homeodomain transcription factor Meis1 is a critical regulator of adult bone marrow hematopoiesis.

PLoS One 2014 3;9(2):e87646. Epub 2014 Feb 3.

Division of Development and Aging, Research Institute for Biomedical Sciences, Tokyo University of Science, Noda, Chiba, Japan.

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December 2014

SLP-76 is required for high-affinity IgE receptor- and IL-3 receptor-mediated activation of basophils.

Int Immunol 2012 Nov 8;24(11):719-27. Epub 2012 Aug 8.

Division of Development and Aging, Research Institute for Biological Sciences, 2669 Yamazaki, Noda, Chiba 278-0022, Japan.

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November 2012

Blocking S1P interaction with S1P₁ receptor by a novel competitive S1P₁-selective antagonist inhibits angiogenesis.

Biochem Biophys Res Commun 2012 Mar 24;419(4):754-60. Epub 2012 Feb 24.

Department of Molecular Function and Pharmacology Laboratories, Taisho Pharmaceutical Co. Ltd., 1-403 Saitama, Saitama 331-9530, Japan.

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March 2012

Lymphopenia induced by a novel selective S1P(1) antagonist structurally unrelated to S1P.

Biochim Biophys Acta 2012 Apr 30;1821(4):600-6. Epub 2011 Dec 30.

Department of Molecular Function and Pharmacology Laboratories, Taisho Pharmaceutical Co. Ltd., 1-403 Yoshino-cho, Saitama-shi, Saitama 331-9520, Japan.

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April 2012

Hypoxia induces CD133 expression in human lung cancer cells by up-regulation of OCT3/4 and SOX2.

Int J Oncol 2012 Jan 22;40(1):71-9. Epub 2011 Sep 22.

Department of Biochemistry, University of Occupational and Environmental Health, Fukuoka, Japan.

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January 2012

New approach for m-cell-specific molecules screening by comprehensive transcriptome analysis.

DNA Res 2009 Aug;16(4):227-35

International Graduate School of Arts and Sciences, Yokohama City University, Kanagawa 230-0045, Japan.

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August 2009

BLNK suppresses pre-B-cell leukemogenesis through inhibition of JAK3.

Blood 2009 Feb 1;113(7):1483-92. Epub 2008 Dec 1.

Division of Molecular Biology, Research Institute for Biological Sciences, Tokyo University of Science, Noda, Japan.

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February 2009

PKC eta directs induction of IRF-4 expression and Ig kappa gene rearrangement in pre-BCR signaling pathway.

Int Immunol 2008 Nov 9;20(11):1417-26. Epub 2008 Sep 9.

Division of Molecular Biology, Tokyo University of Science, Noda, Chiba 278-0022, Japan.

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November 2008

Evolutionarily conserved and divergent regions of the autoimmune regulator (Aire) gene: a comparative analysis.

Immunogenetics 2008 Feb 23;60(2):105-14. Epub 2008 Jan 23.

Department of Microbiology and Immunology, University of Maryland, Baltimore, MD 21201, USA.

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February 2008

Distinct regulatory functions of SLP-76 and MIST in NK cell cytotoxicity and IFN-gamma production.

Int Immunol 2008 Mar 17;20(3):345-52. Epub 2008 Jan 17.

Division of Development and Aging, Research Institute for Biological Sciences, Tokyo University of Science, Noda, Chiba 278-0022, Japan.

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March 2008

Chicken cathelicidin-B1, an antimicrobial guardian at the mucosal M cell gateway.

Proc Natl Acad Sci U S A 2007 Sep 7;104(38):15063-8. Epub 2007 Sep 7.

Research Institute for Biological Sciences, Tokyo University of Science, Noda, Chiba 278-0022, Japan.

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September 2007

IL-7/STAT5 cytokine signaling pathway is essential but insufficient for maintenance of naive CD4 T cell survival in peripheral lymphoid organs.

J Immunol 2007 Jan;178(1):262-70

Laboratory for Signal Network, Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Kanagawa, Japan.

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January 2007

BASH-novel PKC-Raf-1 pathway of pre-BCR signaling induces kappa gene rearrangement.

Blood 2006 Oct 22;108(8):2703-11. Epub 2006 Jun 22.

Division of Molecular Biology, Research Institute for Biological Sciences, Tokyo University of Science, Yamazaki 2669, Noda, Chiba 278-0022, Japan.

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October 2006

A novel avian homologue of CD72, chB1r, down modulates BCR-mediated activation signals.

Int Immunol 2006 May 31;18(5):775-83. Epub 2006 Mar 31.

Research Institute for Biological Sciences, Tokyo University of Science, 2669 Yamazaki, Noda, Chiba 278-0022, Japan.

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May 2006

Double knockout mice show BASH and PKCdelta have different epistatic relationships in B cell maturation and CD40-mediated activation.

Immunol Lett 2006 May 25;105(1):48-54. Epub 2006 Jan 25.

Division of Molecular Biology, Research Institute for Biological Sciences, Tokyo University of Science, 2669 Yamazaki, Noda, Chiba 278-0022, Japan.

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May 2006

Dual function for the adaptor MIST in IFN-gamma production by NK and CD4+NKT cells regulated by the Src kinase Fgr.

Blood 2006 May 26;107(9):3647-55. Epub 2006 Jan 26.

Division of Molecular Biology, Research Institute for Biological Sciences, Tokyo University of Science, 2669 Yamazaki, Noda, Chiba 278-0022, Japan.

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May 2006

Impaired receptor editing in the primary B cell repertoire of BASH-deficient mice.

J Immunol 2004 Nov;173(10):5980-8

Division of Molecular Biology, Research Institute for Biological Sciences, Tokyo University of Science, Yamazaki 2669, Noda, Chiba 278-0022, Japan.

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November 2004

Transcriptional regulation of SLP-76 family hematopoietic cell adaptor MIST/Clnk by STAT5.

Biochem Biophys Res Commun 2004 Aug;321(1):145-53

Research Institute for Biological Sciences, Tokyo University of Science, 2669 Yamazaki, Noda, Chiba 278-0022, Japan.

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August 2004

BASH-deficient mice: limited primary repertoire and antibody formation, but sufficient affinity maturation and memory B cell generation, in anti-NP response.

Int Immunol 2004 Aug 5;16(8):1161-71. Epub 2004 Jul 5.

Division of Molecular Biology, Research Institute for Biological Sciences, Tokyo University of Science, Noda, Chiba, Japan.

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August 2004

Distinct signaling requirements for Dmu selection, IgH allelic exclusion, pre-B cell transition, and tumor suppression in B cell progenitors.

Immunity 2003 Jun;18(6):825-36

Division of Molecular Biology, Research Institute for Biological Sciences, Tokyo University of Science, Yamazaki 2669, Noda, 278-0022, Chiba, Japan.

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June 2003

Targeting of MIST to Src-family kinases via SKAP55-SLAP-130 adaptor complex in mast cells.

FEBS Lett 2003 Apr;540(1-3):111-6

Department of Molecular Biology Laboratory, Medicinal Research Laboratories, Taisho Pharmaceutical Co Ltd, 1-403 Yoshino-cho, Saitama-shi, Saitama 330-8530, Japan.

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April 2003

SMAD1 signaling is critical for initial commitment of germ cell lineage from mouse epiblast.

Mech Dev 2002 Oct;118(1-2):99-109

Division of Molecular Biology, Research Institute for Biological Sciences, Tokyo University of Science, Yamazaki 2669, Noda, Chiba 278-0022, Japan.

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October 2002