Publications by authors named "Ryan Sullivan"

100Publications

Clinical Outcomes of Patients with Metastatic Cancer Receiving Immune Checkpoint Inhibitors in the Inpatient Setting.

Oncologist 2020 Oct 12. Epub 2020 Oct 12.

Division of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1002/onco.13561DOI Listing
October 2020

Aerosol Optical Tweezers Elucidate the Chemistry, Acidity, Phase Separations, and Morphology of Atmospheric Microdroplets.

Acc Chem Res 2020 Oct 9. Epub 2020 Oct 9.

Atmospheric, Earth, & Energy Division, Lawrence Livermore National Laboratory, Livermore, California 94550, United States.

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http://dx.doi.org/10.1021/acs.accounts.0c00407DOI Listing
October 2020

Association Between Immune Checkpoint Inhibitors with Cardiovascular Events and Atherosclerotic Plaque.

Circulation 2020 Oct 2. Epub 2020 Oct 2.

Cardiovascular Imaging Research Center (CIRC), Department of Radiology and Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.120.049981DOI Listing
October 2020

Liver biopsy findings in patients on immune checkpoint inhibitors.

Mod Pathol 2020 Sep 3. Epub 2020 Sep 3.

Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41379-020-00653-1DOI Listing
September 2020

Biomass combustion produces ice-active minerals in biomass-burning aerosol and bottom ash.

Proc Natl Acad Sci U S A 2020 09 24;117(36):21928-21937. Epub 2020 Aug 24.

Center for Atmospheric Particle Studies, Carnegie Mellon University, Pittsburgh, PA 15213

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http://dx.doi.org/10.1073/pnas.1922128117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486733PMC
September 2020

Immune checkpoint inhibitor toxicities: systems-based approaches to improve patient care and research.

Lancet Oncol 2020 08;21(8):e398-e404

Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1016/S1470-2045(20)30107-8DOI Listing
August 2020

In Experimental Dilated Cardiomyopathy Heart Failure and Survival Are Adversely Affected by a Lack of Sexual Interactions.

Int J Mol Sci 2020 Jul 30;21(15). Epub 2020 Jul 30.

Department of Internal Medicine, University of Arizona College of Medicine-Phoenix, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.3390/ijms21155450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432836PMC
July 2020

Acute Kidney Injury Following Encorafenib and Binimetinib for Metastatic Melanoma.

Kidney Med 2020 May-Jun;2(3):373-375. Epub 2020 Apr 18.

Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1016/j.xkme.2020.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380350PMC
April 2020

Molecular Pathways of Colon Inflammation Induced by Cancer Immunotherapy.

Cell 2020 Aug 29;182(3):655-671.e22. Epub 2020 Jun 29.

Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA; Department of Neurology, Brigham & Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415717PMC
August 2020

COVID-19 and immune checkpoint inhibitors: initial considerations.

J Immunother Cancer 2020 05;8(1)

Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/jitc-2020-000933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246104PMC
May 2020

Corin Overexpression Reduces Myocardial Infarct Size and Modulates Cardiomyocyte Apoptotic Cell Death.

Int J Mol Sci 2020 May 14;21(10). Epub 2020 May 14.

Department of Internal Medicine, University of Arizona College of Medicine-Phoenix, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.3390/ijms21103456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278931PMC
May 2020

Adjuvant nivolumab plus ipilimumab for resected stage IV melanoma.

Lancet 2020 05;395(10236):1524-1525

Center for Melanoma, Massachusetts General Hospital Cancer Center, Massachusetts, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(20)31044-8DOI Listing
May 2020

Reaction Cycling for Kinetic Analysis in Flow.

J Org Chem 2020 Apr 1;85(8):5464-5474. Epub 2020 Apr 1.

Centre for Catalysis Research and Innovation, Department of Chemistry and Biomolecular Sciences, University of Ottawa, 10 Marie-Curie, Ottawa, Ontario, Canada K1N 6N5.

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http://dx.doi.org/10.1021/acs.joc.0c00216DOI Listing
April 2020

Case 9-2020: A 64-Year-Old Man with Shortness of Breath, Cough, and Hypoxemia.

N Engl J Med 2020 Mar;382(12):1150-1159

From the Departments of Medicine (K.L.R., R.J.S., M.K.M.), Radiology (F.J.F.), and Pathology (J.E.), Massachusetts General Hospital, and the Departments of Medicine (K.L.R., R.J.S., M.K.M.), Radiology (F.J.F.), and Pathology (J.E.), Harvard Medical School - both in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1909621DOI Listing
March 2020

Severe Neurological Toxicity of Immune Checkpoint Inhibitors: Growing Spectrum.

Ann Neurol 2020 05 10;87(5):659-669. Epub 2020 Mar 10.

Department of Neurology, Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1002/ana.25708DOI Listing
May 2020

Secondary histiocytic sarcoma with BRAF mutation after T-cell acute lymphoblastic leukemia in a very young child with dramatic response to dabrafenib and trametinib.

Pediatr Blood Cancer 2020 05 9;67(5):e28200. Epub 2020 Feb 9.

Department of Pediatrics, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1002/pbc.28200DOI Listing
May 2020

When is it OK to Stop Anti-Programmed Death 1 Receptor (PD-1) Therapy in Metastatic Melanoma?

Am J Clin Dermatol 2020 Jun;21(3):313-321

Center for Melanoma, Massachusetts General Hospital Cancer Center, 55 Fruit Street, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1007/s40257-020-00506-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276295PMC
June 2020

The potential of BRAF-targeted therapy combined with immunotherapy in melanoma.

Expert Rev Anticancer Ther 2020 02 5;20(2):131-136. Epub 2020 Feb 5.

Center for Melanoma, Massachusetts General Hospital Cancer Center, Boston, Massachusetts.

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http://dx.doi.org/10.1080/14737140.2020.1724097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150269PMC
February 2020

Moving beyond Fine Particle Mass: High-Spatial Resolution Exposure to Source-Resolved Atmospheric Particle Number and Chemical Mixing State.

Environ Health Perspect 2020 01 14;128(1):17009. Epub 2020 Jan 14.

Center for Atmospheric Particle Studies, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1289/EHP5311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015569PMC
January 2020

Usability of Learning Moment: Features of an E-learning Tool That Maximize Adoption by Students.

West J Emerg Med 2019 Dec 9;21(1):78-84. Epub 2019 Dec 9.

Boston Medical Center, Department of Emergency Medicine, Boston, Massachusetts.

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http://dx.doi.org/10.5811/westjem.2019.6.42657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948698PMC
December 2019

When Not to Trust the Bladder Scanner. The Use of Point-of-Care Ultrasound to Estimate Urinary Bladder Volume.

Ann Am Thorac Soc 2019 12;16(12):1582-1584

Division of Pulmonary, Allergy, and Critical Care Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1513/AnnalsATS.201905-414CCDOI Listing
December 2019

In Situ pH Measurements of Individual Levitated Microdroplets Using Aerosol Optical Tweezers.

Anal Chem 2020 01 9;92(1):1089-1096. Epub 2019 Dec 9.

Center for Atmospheric Particle Studies , Carnegie Mellon University , Pittsburgh , Pennsylvania 15213 , United States.

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http://dx.doi.org/10.1021/acs.analchem.9b04152DOI Listing
January 2020

NO reactive uptake kinetics and chlorine activation on authentic biomass-burning aerosol.

Environ Sci Process Impacts 2019 Oct;21(10):1684-1698

Department of Atmospheric Science, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1039/c9em00330dDOI Listing
October 2019

Long-term Reoperation Rate for Cubital Tunnel Syndrome: Subcutaneous Transposition Versus In Situ Decompression.

Hand (N Y) 2019 Sep 13:1558944719873153. Epub 2019 Sep 13.

Children's Mercy Hospital, Kansas City, MO, USA.

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http://journals.sagepub.com/doi/10.1177/1558944719873153
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http://dx.doi.org/10.1177/1558944719873153DOI Listing
September 2019

Varied phenotypes and management of immune checkpoint inhibitor-associated neuropathies.

Neurology 2019 09 12;93(11):e1093-e1103. Epub 2019 Aug 12.

From the Departments of Neurology (D.D., W.S.D., A.C.G.), Medicine (K.L.R., D.F.C., J.V.C., D.P.L., M.J.M., R.J.S.), and Pathology (N.F.C.), Massachusetts General Hospital; Department of Neurology (D.D., A.A.A.), Brigham and Women's Hospital, Boston, MA; and Department of Neurology (D.D.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000008091DOI Listing
September 2019

Normalizing Plasma Renin Activity in Experimental Dilated Cardiomyopathy: Effects on Edema, Cachexia, and Survival.

Int J Mol Sci 2019 Aug 9;20(16). Epub 2019 Aug 9.

Department of Internal Medicine, University of Arizona College of Medicine-Phoenix, Phoenix, AZ 85004, USA.

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https://www.mdpi.com/1422-0067/20/16/3886
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http://dx.doi.org/10.3390/ijms20163886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720926PMC
August 2019

Renin Activity in Heart Failure with Reduced Systolic Function-New Insights.

Int J Mol Sci 2019 Jun 28;20(13). Epub 2019 Jun 28.

Department of Internal Medicine, University of Arizona College of Medicine-Phoenix, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.3390/ijms20133182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651297PMC
June 2019

Hypophysitis secondary to nivolumab and pembrolizumab is a clinical entity distinct from ipilimumab-associated hypophysitis.

Eur J Endocrinol 2019 Sep;181(3):211-219

Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1530/EJE-19-0238DOI Listing
September 2019

Back to the Future: Rethinking and Retooling IL2 in the Immune Checkpoint Inhibitor Era.

Authors:
Ryan J Sullivan

Cancer Discov 2019 Jun;9(6):694-695

Massachusetts General Hospital Cancer Center, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-19-0412DOI Listing
June 2019

Frontline Therapy for -Mutated Metastatic Melanoma: How Do You Choose, and Is There One Correct Answer?

Am Soc Clin Oncol Educ Book 2019 Jan 17;39:564-571. Epub 2019 May 17.

4 Massachusetts General Hospital Cancer Center, Boston, MA.

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http://dx.doi.org/10.1200/EDBK_243071DOI Listing
January 2019

Modelling bistable tumour population dynamics to design effective treatment strategies.

J Theor Biol 2019 08 9;474:88-102. Epub 2019 May 9.

Institute of Statistical Science, Academia Sinica, 128 Academia Rd, Sec 2, Nankang, 11529, Taipei, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00225193193019
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http://dx.doi.org/10.1016/j.jtbi.2019.05.005DOI Listing
August 2019

Developments in the Space of New MAPK Pathway Inhibitors for BRAF-Mutant Melanoma.

Clin Cancer Res 2019 10 16;25(19):5735-5742. Epub 2019 Apr 16.

Division of Medical Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center, Center for Melanoma, Harvard Medical School, Boston, Massachusetts.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-18-0836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774830PMC
October 2019

What to Do When Anti-PD-1 Therapy Fails in Patients With Melanoma.

Oncology (Williston Park) 2019 Apr;33(4):141-8

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April 2019

Relationship of the Posterior Condylar Line and the Transepicondylar Axis: A CT-Based Evaluation.

J Knee Surg 2020 Jul 8;33(7):673-677. Epub 2019 Apr 8.

Department of Orthopaedic Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

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http://dx.doi.org/10.1055/s-0039-1685146DOI Listing
July 2020

Using Ionic Liquids To Study the Migration of Semivolatile Organic Vapors in Smog Chamber Experiments.

J Phys Chem A 2019 May 22;123(17):3887-3892. Epub 2019 Apr 22.

Center for Atmospheric Particle Studies , Carnegie Mellon University , Pittsburgh , Pennsylvania 15213 , United States.

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http://dx.doi.org/10.1021/acs.jpca.9b02847DOI Listing
May 2019

Autoimmune genetic risk variants as germline biomarkers of response to melanoma immune-checkpoint inhibition.

Cancer Immunol Immunother 2019 Jun 12;68(6):897-905. Epub 2019 Mar 12.

Laura and Issac Perlmutter Cancer Center, New York University School of Medicine, 522 First Avenue, New York, NY, 10016, USA.

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http://dx.doi.org/10.1007/s00262-019-02318-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531317PMC
June 2019

The future of combination treatment with checkpoint inhibitors in melanoma.

Authors:
Ryan J Sullivan

Clin Adv Hematol Oncol 2019 Feb;17(2):96-99

Harvard Medical School, Boston, Massachusetts.

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February 2019

The Effect of Implant Design on Sagittal Plane Stability: A Randomized Trial of Medial- versus Posterior-Stabilized Total Knee Arthroplasty.

J Knee Surg 2020 May 8;33(5):452-458. Epub 2019 Feb 8.

Department of Orthopaedic Surgery, Northwestern University, Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1055/s-0039-1678524DOI Listing
May 2020

High Throughput Strategies for the Discovery and Optimization of Catalytic Reactions.

Angew Chem Int Ed Engl 2019 05 12;58(22):7180-7191. Epub 2019 Mar 12.

Centre for Catalysis Research and Innovation, Department of Chemistry and Biomolecular Sciences, University of Ottawa, 10 Marie-Curie, Ottawa, Ontario, K1N 6N5, Canada.

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http://dx.doi.org/10.1002/anie.201812534DOI Listing
May 2019

Musculoskeletal rheumatic complications of immune checkpoint inhibitor therapy: A single center experience.

Semin Arthritis Rheum 2019 06 16;48(6):1127-1132. Epub 2018 Oct 16.

Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA, United States; Harvard Medical School, Boston, MA, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00490172183044
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http://dx.doi.org/10.1016/j.semarthrit.2018.10.012DOI Listing
June 2019

Meta-analysis of aberrant post-error slowing in substance use disorder: implications for behavioral adaptation and self-control.

Eur J Neurosci 2019 08 3;50(3):2467-2476. Epub 2018 Dec 3.

Department of Psychiatry, Stony Brook University School of Medicine, Health Sciences Center 10-087F, 101 Nicolls Road, Stony Brook, NY, 11794, USA.

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http://doi.wiley.com/10.1111/ejn.14229
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http://dx.doi.org/10.1111/ejn.14229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494729PMC
August 2019

Reply to emergency management of immune-related hypophysitis: Collaboration between specialists is essential to achieve optimal outcomes.

Cancer 2018 12 23;124(24):4732. Epub 2018 Oct 23.

Center for Melanoma, Massachusetts General Hospital Cancer Center, Boston, Massachusetts.

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http://doi.wiley.com/10.1002/cncr.31786
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http://dx.doi.org/10.1002/cncr.31786DOI Listing
December 2018

Publisher Correction: Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma.

Nat Med 2018 Dec;24(12):1942

Center for Bioinformatics and Computational Biology, Department of Computer Science, University of Maryland, College Park, MD, USA.

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http://dx.doi.org/10.1038/s41591-018-0247-8DOI Listing
December 2018

A Novel Web-Based Experiential Learning Platform for Medical Students (Learning Moment): Qualitative Study.

JMIR Med Educ 2018 Oct 17;4(2):e10657. Epub 2018 Oct 17.

Department of Emergency Medicine, Boston Medical Center, Boston, MA, United States.

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http://mededu.jmir.org/2018/2/e10657/
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http://dx.doi.org/10.2196/10657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231881PMC
October 2018

Mechanisms of Resistance to Immune Checkpoint Blockade.

Am J Clin Dermatol 2019 Feb;20(1):41-54

Division of Medical Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center, Harvard Medical School, 55 Fruit Street, Yawkey 7E, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1007/s40257-018-0389-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358473PMC
February 2019

Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma.

Nat Med 2018 10 20;24(10):1545-1549. Epub 2018 Aug 20.

Center for Bioinformatics and Computational Biology, Department of Computer Science, University of Maryland, College Park, MD, USA.

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http://www.nature.com/articles/s41591-018-0157-9
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http://dx.doi.org/10.1038/s41591-018-0157-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693632PMC
October 2018

The role of targeted therapy for melanoma in the immunotherapy era.

Authors:
Ryan J Sullivan

Semin Cutan Med Surg 2018 Jun;37(2):112-119

Center for Melanoma, MGH Cancer Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.12788/j.sder.2018.021DOI Listing
June 2018

Forestalling BRAF-Inhibitor Resistance in a Shocking Way.

Authors:
Ryan J Sullivan

Clin Cancer Res 2018 11 6;24(22):5496-5498. Epub 2018 Jul 6.

Massachusetts General Hospital Cancer Center, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-1344DOI Listing
November 2018

High-dose glucocorticoids for the treatment of ipilimumab-induced hypophysitis is associated with reduced survival in patients with melanoma.

Cancer 2018 09 5;124(18):3706-3714. Epub 2018 Jul 5.

Center for Melanoma, Massachusetts General Hospital Cancer Center, Boston, Massachusetts.

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http://dx.doi.org/10.1002/cncr.31629DOI Listing
September 2018

New mouse model of pulmonary hypertension induced by respiratory syncytial virus bronchiolitis.

Am J Physiol Heart Circ Physiol 2018 09 15;315(3):H581-H589. Epub 2018 Jun 15.

Department of Pediatrics, University of Tennessee Health Science Center, Children's Foundation Research Institute, Le Bonheur Children's Hospital , Memphis, Tennessee.

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http://dx.doi.org/10.1152/ajpheart.00627.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172644PMC
September 2018

Emerging investigator series: determination of biphasic core-shell droplet properties using aerosol optical tweezers.

Environ Sci Process Impacts 2018 Nov;20(11):1512-1523

Center for Atmospheric Particle Studies, Carnegie Mellon University, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1039/c8em00166aDOI Listing
November 2018