Ryan Abo

Ryan Abo

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Ryan Abo

Ryan Abo

Publications by authors named "Ryan Abo"

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Enabling drug discovery for the PARP protein family through the detection of mono-ADP-ribosylation.

Biochem Pharmacol 2019 Sep 7;167:97-106. Epub 2019 May 7.

Department of Biological Sciences, Ribon Therapeutics, Inc., Cambridge, MA 02140, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2019.05.007DOI Listing
September 2019

BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers.

Nucleic Acids Res 2015 Feb 26;43(3):e19. Epub 2014 Nov 26.

Center for Cancer Genome Discovery and Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA Department of Pathology, Brigham and Women's Hospital, Boston, MA 02215, USA

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http://dx.doi.org/10.1093/nar/gku1211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330340PMC
February 2015

Diverse cell stresses induce unique patterns of tRNA up- and down-regulation: tRNA-seq for quantifying changes in tRNA copy number.

Nucleic Acids Res 2014 Dec 27;42(22):e170. Epub 2014 Oct 27.

Department of Biological Engineering and Infectious Diseases Interdisciplinary Research Group, Singapore-MIT Alliance for Research & Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA

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http://dx.doi.org/10.1093/nar/gku945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267671PMC
December 2014

Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis.

Proc Natl Acad Sci U S A 2014 May 22;111(18):E1823-32. Epub 2014 Apr 22.

Department of Biological Engineering, Center for Environmental Health Sciences, Department of Biology, and The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139.

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http://dx.doi.org/10.1073/pnas.1401182111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020053PMC
May 2014

Global analysis of cell cycle gene expression of the legume symbiont Sinorhizobium meliloti.

Proc Natl Acad Sci U S A 2014 Mar 5;111(9):3217-24. Epub 2014 Feb 5.

Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139.

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http://dx.doi.org/10.1073/pnas.1400421111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948222PMC
March 2014

Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines.

BMC Genomics 2014 Feb 1;15:93. Epub 2014 Feb 1.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1186/1471-2164-15-93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930546PMC
February 2014

Integrative gene set analysis: application to platinum pharmacogenomics.

OMICS 2014 Jan 7;18(1):34-41. Epub 2013 Nov 7.

1 Department of Biostatistics, University of Kansas Medical Center , Kansas City, Kansas.

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http://dx.doi.org/10.1089/omi.2013.0099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903166PMC
January 2014

Gut microbiome perturbations induced by bacterial infection affect arsenic biotransformation.

Chem Res Toxicol 2013 Dec 18;26(12):1893-903. Epub 2013 Nov 18.

Department of Biological Engineering, ‡Department of Biology, §Division of Comparative Medicine, and ∥Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02139, United States.

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http://dx.doi.org/10.1021/tx4002868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974266PMC
December 2013

Identifying the genetic variation of gene expression using gene sets: application of novel gene Set eQTL approach to PharmGKB and KEGG.

PLoS One 2012 14;7(8):e43301. Epub 2012 Aug 14.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0043301PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419168PMC
February 2013

Simultaneous analysis of multiple data types in pharmacogenomic studies using weighted sparse canonical correlation analysis.

OMICS 2012 Jul-Aug;16(7-8):363-73. Epub 2012 Jun 26.

Biostatistics Department, University of Kansas Medical Center, Kansas City, Kansas, USA.

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http://dx.doi.org/10.1089/omi.2011.0126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394856PMC
November 2012

Shared genomic segment analysis: the power to find rare disease variants.

Ann Hum Genet 2012 Nov 19;76(6):500-9. Epub 2012 Sep 19.

Division of Genetic Epidemiology, University of Utah School of Medicine, Salt Lake City, UT 84108, USA.

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http://dx.doi.org/10.1111/j.1469-1809.2012.00728.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879794PMC
November 2012

Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization.

J Neurochem 2012 Mar 6;120(6):881-90. Epub 2012 Feb 6.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2012.07646.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296836PMC
March 2012

Fine-mapping CASP8 risk variants in breast cancer.

Cancer Epidemiol Biomarkers Prev 2012 Jan 4;21(1):176-81. Epub 2011 Nov 4.

Division of Genetic Epidemiology, University of Utah School of Medicine, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-11-0845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253962PMC
January 2012

Methionine adenosyltransferase 2A/2B and methylation: gene sequence variation and functional genomics.

Drug Metab Dispos 2011 Nov 3;39(11):2135-47. Epub 2011 Aug 3.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1124/dmd.111.040857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198898PMC
November 2011

Genetic variation predicting cisplatin cytotoxicity associated with overall survival in lung cancer patients receiving platinum-based chemotherapy.

Clin Cancer Res 2011 Sep 20;17(17):5801-11. Epub 2011 Jul 20.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-1133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167019PMC
September 2011

Betaine-homocysteine methyltransferase: human liver genotype-phenotype correlation.

Mol Genet Metab 2011 Feb 21;102(2):126-33. Epub 2010 Oct 21.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1016/j.ymgme.2010.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053054PMC
February 2011

Automated construction and testing of multi-locus gene-gene associations.

Bioinformatics 2011 Jan 13;27(1):134-6. Epub 2010 Nov 13.

Department of Biomedical Informatics, University of Utah School of Medicine, UT, USA.

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http://dx.doi.org/10.1093/bioinformatics/btq616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008644PMC
January 2011

Exploring multilocus associations of inflammation genes and colorectal cancer risk using hapConstructor.

BMC Med Genet 2010 Dec 3;11:170. Epub 2010 Dec 3.

Epidemiology, Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.1186/1471-2350-11-170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006374PMC
December 2010

Haplotype association analyses in resources of mixed structure using Monte Carlo testing.

BMC Bioinformatics 2010 Dec 9;11:592. Epub 2010 Dec 9.

Department of Biomedical Informatics, University of Utah, Salt Lake City, USA.

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http://dx.doi.org/10.1186/1471-2105-11-592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016409PMC
December 2010

Pedigree association: assigning individual weights to pedigree members for genetic association analysis.

BMC Proc 2009 Dec 15;3 Suppl 7:S121. Epub 2009 Dec 15.

Biomedical Informatics Department, University of Utah, 26 South 2000 East Room 5775 HSEB, Salt Lake City, Utah 84112, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795894PMC
http://dx.doi.org/10.1186/1753-6561-3-s7-s121DOI Listing
December 2009

Evaluation of genetic risk scores for lipid levels using genome-wide markers in the Framingham Heart Study.

BMC Proc 2009 Dec 15;3 Suppl 7:S46. Epub 2009 Dec 15.

Department of Biomedical Informatics, School of Medicine, University of Utah, 26 South 2000 East, Salt Lake City, Utah 84112, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795945PMC
http://dx.doi.org/10.1186/1753-6561-3-s7-s46DOI Listing
December 2009

hapConstructor: automatic construction and testing of haplotypes in a Monte Carlo framework.

Bioinformatics 2008 Sep 23;24(18):2105-7. Epub 2008 Jul 23.

Department of Biomedical Informatics, University of Utah, UT, USA.

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http://dx.doi.org/10.1093/bioinformatics/btn359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2530882PMC
September 2008