Ruxandra Draghia-Akli

Ruxandra Draghia-Akli

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Ruxandra Draghia-Akli

Ruxandra Draghia-Akli

Publications by authors named "Ruxandra Draghia-Akli"

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Progress in Rare Diseases Research 2010-2016: An IRDiRC Perspective.

Clin Transl Sci 2018 01 23;11(1):11-20. Epub 2017 Oct 23.

National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Bethesda, Maryland, USA.

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http://dx.doi.org/10.1111/cts.12501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759730PMC
January 2018

Enabling personalized medicine in Europe by the European Commission's funding activities.

Per Med 2017 07 23;14(4):355-365. Epub 2017 Jun 23.

Directorate-General for Research & Innovation, European Commission, B-1049 Brussels, Belgium.

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http://dx.doi.org/10.2217/pme-2017-0003DOI Listing
July 2017

European Union research in support of environment and health: Building scientific evidence base for policy.

Environ Int 2017 06 3;103:51-60. Epub 2017 Apr 3.

European Commission, Research and Innovation Directorate-General, Health Directorate, B-1049 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.envint.2017.03.014DOI Listing
June 2017

Understanding the brain through large, multidisciplinary research initiatives.

Lancet Neurol 2017 03 15;16(3):183-184. Epub 2017 Feb 15.

Directorate-General for Research & Innovation, European Commission, Brussels, Belgium.

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http://dx.doi.org/10.1016/S1474-4422(17)30020-0DOI Listing
March 2017

New Vaccines against Epidemic Infectious Diseases.

N Engl J Med 2017 Feb 18;376(7):610-613. Epub 2017 Jan 18.

From the Coalition for Epidemic Preparedness Innovations (CEPI), the Norwegian Institute of Public Health, and the University of Oslo - all in Oslo (J.-A.R., D.G.); the Harvard T.H. Chan School of Public Health, Boston (J.-A.R.); Chatham House (J.-A.R.), GlaxoSmithKline (A.W.), and the London School of Hygiene and Tropical Medicine (P.P.) - all in London; the International AIDS Vaccine Initiative (M.F.) and Johnson & Johnson (P.S.) - both in New York; the University of Pennsylvania, Philadelphia (S.P.); the Department of Biotechnology, Ministry of Science and Technology, New Delhi, India (K.V.R.); and the Directorate General for Research and Innovation, European Commission, Brussels (R.D.-A.).

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http://dx.doi.org/10.1056/NEJMp1613577DOI Listing
February 2017

European strategy for vaccine development against infectious diseases.

Vaccine 2017 01 22;35 Suppl 1:A20-A23. Epub 2016 Dec 22.

Directorate-General for Research and Innovation, European Commission, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.vaccine.2016.10.031DOI Listing
January 2017

The need for innovation and implementation research for maternal and newborn health.

Lancet 2016 Oct 16;388(10052):1374. Epub 2016 Sep 16.

Fighting Infectious Diseases and Advancing Public Health Unit, Directorate-General Research & Innovation, European Commission, B1049 Brussels, Belgium.

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http://dx.doi.org/10.1016/S0140-6736(16)31662-2DOI Listing
October 2016

Increased momentum in antimicrobial resistance research.

Lancet 2016 Aug 25;388(10047):865. Epub 2016 Aug 25.

Health Directorate, Directorate-General Research & Innovation, European Commission, B1049 Brussels, Belgium.

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http://dx.doi.org/10.1016/S0140-6736(16)31425-8DOI Listing
August 2016

Opportunities for vaccine research in Europe.

Hum Vaccin Immunother 2015 ;11(8):1917-20

a Directorate Health ; Directorate-General for Research and Innovation; European Commission ; Brussels , Belgium.

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http://dx.doi.org/10.1080/21645515.2015.1016680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635889PMC
May 2016

Chronic respiratory diseases and lung cancer research: a perspective from the European Union.

Eur Respir J 2015 Nov 24;46(5):1270-80. Epub 2015 Sep 24.

European Commission, Directorate General for Research and Innovation, Health Directorate, Brussels, Belgium.

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http://dx.doi.org/10.1183/13993003.00395-2015DOI Listing
November 2015

Introduction: Gene Therapy and Gene Transfer Projects of the 7th Framework Programme for Research and Technological Development of the European Union (Second Part).

Hum Gene Ther Clin Dev 2015 Jun;26(2):77

Directorate Health, Directorate-General for Research and Innovation , European Commission, B-1049 Brussels, Belgium .

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http://www.liebertpub.com/doi/10.1089/humc.2015.2518
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http://dx.doi.org/10.1089/humc.2015.2518DOI Listing
June 2015

Better safe than sorry: ethics review in European Union-funded health research.

Stem Cells Dev 2014 Dec;23 Suppl 1:47-50

DG Research & Innovation , European Commission, Brussels, Belgium .

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http://dx.doi.org/10.1089/scd.2014.0328DOI Listing
December 2014

Introduction: gene and cell therapy projects of the seventh framework program.

Hum Gene Ther Clin Dev 2014 Jun;25(2):51

Directorate Health, Directorate-General for Research and Innovation , European Commission, B-1049 Brussels, Belgium .

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http://www.liebertpub.com/doi/10.1089/humc.2014.2501
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http://dx.doi.org/10.1089/humc.2014.2501DOI Listing
June 2014

Gene and cell therapy funding opportunities in horizon 2020: an overview for 2014-2015.

Hum Gene Ther 2014 Mar 21;25(3):175-7. Epub 2014 Feb 21.

Directorate Health, Directorate-General for Research and Innovation, European Commission, Brussels B-1049, Belgium .

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http://www.liebertpub.com/doi/10.1089/hum.2014.017
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http://dx.doi.org/10.1089/hum.2014.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955961PMC
March 2014

A database on global health research in Africa.

Lancet Glob Health 2013 Aug 5;1(2):e64-e65. Epub 2013 Jul 5.

Fogarty International Center, National Institutes of Health, USA. Electronic address:

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http://dx.doi.org/10.1016/S2214-109X(13)70012-3DOI Listing
August 2013

Emphasising the European Union's Commitment to Cancer Research: a helicopter view of the Seventh Framework Programme for Research and Technological Development.

Oncologist 2012 ;17(10):e26-32

European Commission, Directorate General for Research and Innovation, Health Directorate, Medical Research Unit, B-1049 Brussels, Belgium.

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http://dx.doi.org/10.1634/theoncologist.2012-0327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481902PMC
June 2013

Enabling personalized medicine in Europe: a look at the European Commission's funding activities in the field of personalized medicine research.

Per Med 2012 Mar;9(2):151-155

Health Directorate, Directorate-General for Research & Innovation, European Commission, Brussels, Belgium.

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http://dx.doi.org/10.2217/pme.11.91DOI Listing
March 2012

European Union vaccine research--an overview.

Vaccine 2011 Sep 31;29(39):6723-7. Epub 2010 Dec 31.

Directorate Health, Directorate-General of Research, European Commission, CDMA 2/187, B-1049 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.vaccine.2010.12.060DOI Listing
September 2011

Electroporation of plasmid DNA to swine muscle.

Methods Mol Biol 2011 ;709:257-64

Inovio Biomedical Corporation, 2700 Research Forest Drive, The Woodlands, TX, USA.

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http://dx.doi.org/10.1007/978-1-61737-982-6_16DOI Listing
July 2011

A look inside the framework: EU funding priorities and criteria in the health theme of the co-operation programme.

Bioessays 2010 Nov 7;32(11):923-5. Epub 2010 Sep 7.

Health Research, European Commission-DG Research, Brussels, Belgium.

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http://dx.doi.org/10.1002/bies.201000059DOI Listing
November 2010

Lost without translation. EC's science-friendly future.

BMJ 2010 Sep 22;341:c5016. Epub 2010 Sep 22.

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http://dx.doi.org/10.1136/bmj.c5016DOI Listing
September 2010

Production of pharmaceutical-grade plasmids at high concentration and high supercoiled percentage.

Vaccine 2010 Feb 5;28(8):2046-52. Epub 2009 Nov 5.

VGX Pharmaceuticals, Inc., The Woodlands, TX 77381, United States.

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http://dx.doi.org/10.1016/j.vaccine.2009.10.057DOI Listing
February 2010

Effects of maternal plasmid GHRH treatment on offspring growth.

Vaccine 2010 Feb;28(8):1905-10

VGX Pharmaceuticals, Inc., 2700 Research Forest Drive, The Woodlands, TX 77381, USA.

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http://dx.doi.org/10.1016/j.vaccine.2009.10.093DOI Listing
February 2010

Systemic immunization with CCL27/CTACK modulates immune responses at mucosal sites in mice and macaques.

Vaccine 2010 Feb;28(8):1942-51

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6100, United States.

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http://dx.doi.org/10.1016/j.vaccine.2009.10.095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396814PMC
February 2010

High dose of plasmid IL-15 inhibits immune responses in an influenza non-human primates immunogenicity model.

Virology 2009 Oct 15;393(1):49-55. Epub 2009 Aug 15.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 505 SCL, 422 Curie Blvd. Philadelphia, PA 19104, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S004268220900424
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http://dx.doi.org/10.1016/j.virol.2009.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118595PMC
October 2009

Electroporation for the delivery of DNA-based vaccines and immunotherapeutics: current clinical developments.

Mol Ther 2009 Apr 17;17(4):585-92. Epub 2009 Feb 17.

VGX Pharmaceuticals, Inc., 2700 Research Forest Drive, Suite 180, The Woodlands, Texas 77381, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S152500161631550
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http://dx.doi.org/10.1038/mt.2009.5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835112PMC
April 2009

In vivo electroporation of gene sequences for therapeutic and vaccination applications.

Recent Pat DNA Gene Seq 2007 ;1(3):207-13

VGX Pharmaceuticals, Immune Therapeutics Division, The Woodlands, Texas 77381, USA.

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March 2009

Gene therapy by electroporation for the treatment of chronic renal failure in companion animals.

BMC Biotechnol 2009 Jan 16;9. Epub 2009 Jan 16.

VGX Animal Health, 2700 Research Forest Drive, Suite 180, The Woodlands, Texas 77381, USA.

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http://bmcbiotechnol.biomedcentral.com/articles/10.1186/1472
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http://dx.doi.org/10.1186/1472-6750-9-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663557PMC
January 2009

Strong HCV NS3- and NS4A-specific cellular immune responses induced in mice and Rhesus macaques by a novel HCV genotype 1a/1b consensus DNA vaccine.

Vaccine 2008 Nov 8;26(49):6225-31. Epub 2008 Aug 8.

Department of Pathology and Laboratory Medicine, University of Pennsylvania, 505 Stellar-Chance Laboratories, 422 Curie Boulevard, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.vaccine.2008.07.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477808PMC
November 2008

Growth hormone-releasing hormone plasmid treatment by electroporation decreases offspring mortality over three pregnancies.

Mol Ther 2008 Nov 19;16(11):1891-7. Epub 2008 Aug 19.

QAF Meat Industries, Corowa, New South Wales, Australia.

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http://dx.doi.org/10.1038/mt.2008.178DOI Listing
November 2008

Effects of plasmid growth hormone-releasing hormone treatment during heat stress.

DNA Cell Biol 2008 Nov;27(11):629-35

VGX Animal Health, The Woodlands, Texas 77381, USA.

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http://www.liebertpub.com/doi/10.1089/dna.2008.0758
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http://dx.doi.org/10.1089/dna.2008.0758DOI Listing
November 2008

Parameters for DNA vaccination using adaptive constant-current electroporation in mouse and pig models.

Vaccine 2008 Sep 15;26(40):5230-7. Epub 2008 Apr 15.

VGX Pharmaceuticals, 2700 Research Forest Drive, Suite 180, The Woodlands, TX 77381, United States.

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http://dx.doi.org/10.1016/j.vaccine.2008.03.071DOI Listing
September 2008

Cellular immunity induced by a novel HPV18 DNA vaccine encoding an E6/E7 fusion consensus protein in mice and rhesus macaques.

Vaccine 2008 Sep 14;26(40):5210-5. Epub 2008 Apr 14.

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.vaccine.2008.03.069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477833PMC
September 2008

Increased immune responses in rhesus macaques by DNA vaccination combined with electroporation.

Vaccine 2008 Sep 21;26(40):5223-9. Epub 2008 Apr 21.

Human Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702-1201, United States.

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http://dx.doi.org/10.1016/j.vaccine.2008.03.090DOI Listing
September 2008

DNA vaccination and gene therapy: optimization and delivery for cancer therapy.

Expert Rev Vaccines 2008 Sep;7(7):1085-101

VGX Pharmaceuticals Inc., 2700 Research Forest Drive, Suite 180, The Woodlands, TX 77381, USA.

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http://www.tandfonline.com/doi/full/10.1586/14760584.7.7.108
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http://dx.doi.org/10.1586/14760584.7.7.1085DOI Listing
September 2008

Delivery of DNA into skeletal muscle in large animals.

Methods Mol Biol 2008 ;423:215-24

VGX Animal Health, The Woodlands, TX, USA.

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http://dx.doi.org/10.1007/978-1-59745-194-9_15DOI Listing
June 2008

Muscle and fat mass modulation in different clinical models.

Methods Mol Biol 2008 ;423:449-60

VGX Pharmaceuticals, Immune Therapeutics Division, The Woodlands, TX, USA.

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http://dx.doi.org/10.1007/978-1-59745-194-9_35DOI Listing
June 2008

Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques.

Vaccine 2008 Jun 11;26(25):3112-20. Epub 2008 Mar 11.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 422 Curie Boulevard, 505 SCL, Philadelphia, PA 19104, United States.

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http://dx.doi.org/10.1016/j.vaccine.2008.02.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477809PMC
June 2008

Plasmid growth hormone releasing hormone therapy in healthy and laminitis-afflicted horses-evaluation and pilot study.

J Gene Med 2008 May;10(5):564-74

VGX Animal Health, The Woodlands, Texas 77381, USA.

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http://dx.doi.org/10.1002/jgm.1170DOI Listing
May 2008

HIV-1 Env vaccine comprised of electroporated DNA and protein co-administered with Talabostat.

Biochem Biophys Res Commun 2008 May 7;370(1):22-6. Epub 2008 Mar 7.

Advanced BioScience Laboratories, Inc., 5510 Nicholson Lane, Kensington, MD 20895, USA.

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http://dx.doi.org/10.1016/j.bbrc.2008.02.145DOI Listing
May 2008

Double-blinded, Placebo-controlled plasmid GHRH trial for cancer-associated anemia in dogs.

Mol Ther 2008 May 18;16(5):862-70. Epub 2008 Mar 18.

VGX Pharmaceuticals, The Woodlands, Texas 77381, USA.

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http://dx.doi.org/10.1038/mt.2008.31DOI Listing
May 2008

Persistent antibody and T cell responses induced by HIV-1 DNA vaccine delivered by electroporation.

Biochem Biophys Res Commun 2008 Feb 26;366(1):29-35. Epub 2007 Nov 26.

Advanced BioScience Laboratories, Inc., Department of Cell Biology, 5510 Nicholson Lane, Kensington, MD 20895, USA.

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http://dx.doi.org/10.1016/j.bbrc.2007.11.052DOI Listing
February 2008

Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques.

Vaccine 2008 Jan 8;26(3):440-8. Epub 2007 Nov 8.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 422 Curie Boulevard, 505 SCL, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.vaccine.2007.10.041DOI Listing
January 2008

Transplacental transfer of a growth hormone-releasing hormone peptide from mother to fetus in the rat.

DNA Cell Biol 2006 Aug;25(8):429-37

USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1089/dna.2006.25.429DOI Listing
August 2006

Successful parallel development and integration of a plasmid-based biologic, container/closure system and electrokinetic delivery device.

Vaccine 2006 May 24;24(21):4607-14. Epub 2005 Aug 24.

ADViSYS Inc., 2700 Research Forest Drive, Suite 180, The Woodlands, TX 77381, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0264410X0500831
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http://dx.doi.org/10.1016/j.vaccine.2005.08.049DOI Listing
May 2006

Electroporation-enhanced nonviral gene transfer for the prevention or treatment of immunological, endocrine and neoplastic diseases.

Curr Gene Ther 2006 Apr;6(2):243-73

Department of Laboratory Medicine, St. Michael's Hospital and University of Toronto, 30 Bond Street, Ontario, Canada M5B1W8.

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April 2006

Highly efficient constant-current electroporation increases in vivo plasmid expression.

DNA Cell Biol 2005 Dec;24(12):810-8

ADViSYS, Inc., The Woodlands, TX 77381, USA.

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http://dx.doi.org/10.1089/dna.2005.24.810DOI Listing
December 2005

Plasmid-based growth hormone-releasing hormone supplementation and its applications.

Curr Opin Mol Ther 2005 Aug;7(4):306-16

ADViSYS Inc, 2700 Research Forest Drive, Suite 180, The Woodlands, TX 77381, USA.

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August 2005

Immune-enhancing effects of growth hormone-releasing hormone delivered by plasmid injection and electroporation.

Mol Ther 2004 Oct;10(4):644-51

ADViSYS, Inc., 2700 Research Forest Drive, Suite 180, The Woodlands, TX 77381, USA.

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http://dx.doi.org/10.1016/j.ymthe.2004.06.1015DOI Listing
October 2004

Long-term effects of plasmid-mediated growth hormone releasing hormone in dogs.

Cancer Gene Ther 2004 May;11(5):389-96

ADViSYS, Inc., The Woodlands, Texas 77381, USA.

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http://dx.doi.org/10.1038/sj.cgt.7700717DOI Listing
May 2004

Insulin-like growth factor I plasmid therapy promotes in vivo angiogenesis.

Mol Ther 2004 Jan;9(1):46-55

Division of Plastic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1016/j.ymthe.2003.10.003DOI Listing
January 2004

Maternal GHRH plasmid administration changes pituitary cell lineage and improves progeny growth of pigs.

Am J Physiol Endocrinol Metab 2003 Jul 1;285(1):E224-31. Epub 2003 Apr 1.

ADViSYS, Inc., The Woodlands, TX 77381, USA.

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http://dx.doi.org/10.1152/ajpendo.00050.2003DOI Listing
July 2003

High-efficiency growth hormone-releasing hormone plasmid vector administration into skeletal muscle mediated by electroporation in pigs.

FASEB J 2003 Mar 2;17(3):526-8. Epub 2003 Jan 2.

Department of Molecular and Cellular Biology, Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas, USA.

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http://dx.doi.org/10.1096/fj.02-0671fjeDOI Listing
March 2003

Electrical enhancement of formulated plasmid delivery in animals.

Technol Cancer Res Treat 2002 Oct;1(5):365-72

Advisys, Inc., 2700 Research Forest Drive, Suite 180, The Woodlands, Texas 77381, USA.

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http://dx.doi.org/10.1177/153303460200100507DOI Listing
October 2002

Nonhereditary enhancement of progeny growth.

Endocrinology 2002 Sep;143(9):3561-7

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1210/en.2002-220282DOI Listing
September 2002

Enhanced animal growth via ligand-regulated GHRH myogenic-injectable vectors.

FASEB J 2002 Mar 14;16(3):426-8. Epub 2002 Jan 14.

Department of Molecular and Cellular Biology, Center for Cell and Gene Therapy, ASR-USDA Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1096/fj.01-0702fjeDOI Listing
March 2002