Ruth S Slack

Ruth S Slack

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Ruth S Slack

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Pink1 regulates FKBP5 interaction with AKT/PHLPP and protects neurons from neurotoxin stress induced by MPP.

J Neurochem 2019 Aug 2;150(3):312-329. Epub 2019 Apr 2.

Department of Cogno-Mechatronics Engineering, Pusan National University, Busan, South Korea.

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http://dx.doi.org/10.1111/jnc.14683DOI Listing
August 2019

The pro-death role of Cited2 in stroke is regulated by E2F1/4 transcription factors.

J Biol Chem 2019 May 9;294(21):8617-8629. Epub 2019 Apr 9.

From the University of Ottawa Brain and Mind Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada,

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http://dx.doi.org/10.1074/jbc.RA119.007941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544850PMC
May 2019

DJ-1 modulates the unfolded protein response and cell death via upregulation of ATF4 following ER stress.

Cell Death Dis 2019 Feb 12;10(2):135. Epub 2019 Feb 12.

Department of Clinical Neurosciences, and Cell Biology and Anatomy, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.

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http://dx.doi.org/10.1038/s41419-019-1354-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372623PMC
February 2019

Mitochondria as central regulators of neural stem cell fate and cognitive function.

Nat Rev Neurosci 2019 Jan;20(1):34-48

Department of Cellular and Molecular Medicine, University of Ottawa Brain and Mind Research Institute, Ottawa, Ontario, Canada.

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http://www.nature.com/articles/s41583-018-0091-3
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http://dx.doi.org/10.1038/s41583-018-0091-3DOI Listing
January 2019

Mitochondrial dynamics in the regulation of neurogenesis: From development to the adult brain.

Dev Dyn 2018 01 13;247(1):47-53. Epub 2017 Jul 13.

Department of Cellular and Molecular Medicine, University of Ottawa Brain and Mind Research Institute, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1002/dvdy.24538DOI Listing
January 2018

Mitochondrial activity in the regulation of stem cell self-renewal and differentiation.

Curr Opin Cell Biol 2017 12 22;49:1-8. Epub 2017 Nov 22.

Department of Cellular and Molecular Medicine, University of Ottawa Brain and Mind Research Institute, 451 Smyth Rd, Ottawa, Ontario K1H 8M5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ceb.2017.11.003DOI Listing
December 2017

PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress.

Nat Commun 2017 11 9;8(1):1399. Epub 2017 Nov 9.

University of Ottawa Brain and Mind Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada, K1H 8M5.

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http://dx.doi.org/10.1038/s41467-017-01435-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680261PMC
November 2017

Modeling Neuronal Death and Degeneration in Mouse Primary Cerebellar Granule Neurons.

J Vis Exp 2017 11 6(129). Epub 2017 Nov 6.

Lady Davis Institute for Medical Research, Jewish General Hospital; Integrated Program in Neuroscience, McGill University; Department of Oncology, Faculty of Medicine, McGill University;

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http://dx.doi.org/10.3791/55871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755328PMC
November 2017

Mitochondrial dysfunction underlies cognitive defects as a result of neural stem cell depletion and impaired neurogenesis.

Hum Mol Genet 2017 09;26(17):3327-3341

Department of Cellular and Molecular Medicine, University of Ottawa Brain and Mind Research Institute, Ottawa, ON K1H 8M5, Canada.

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http://dx.doi.org/10.1093/hmg/ddx217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886206PMC
September 2017

Cdc25A Is a Critical Mediator of Ischemic Neuronal Death and .

J Neurosci 2017 07 12;37(28):6729-6740. Epub 2017 Jun 12.

University of Ottawa Brain and Mind Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada, and

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http://dx.doi.org/10.1523/JNEUROSCI.3017-16.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596551PMC
July 2017

Mitochondrial and Reactive Oxygen Species Signaling Coordinate Stem Cell Fate Decisions and Life Long Maintenance.

Antioxid Redox Signal 2017 Jul 31. Epub 2017 Jul 31.

Department of Cellular and Molecular Medicine, Brain and Mind Research Institute, University of Ottawa , Ottawa, Canada .

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http://dx.doi.org/10.1089/ars.2017.7228DOI Listing
July 2017

RB: An essential player in adult neurogenesis.

Neurogenesis (Austin) 2017 7;4(1):e1270382. Epub 2017 Feb 7.

University of Ottawa Brain and Mind Research Institute, Department of Cellular & Molecular Medicine, University of Ottawa , Ottawa, ON, Canada.

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http://dx.doi.org/10.1080/23262133.2016.1270382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305166PMC
February 2017

RB regulates the production and the survival of newborn neurons in the embryonic and adult dentate gyrus.

Hippocampus 2016 11 8;26(11):1379-1392. Epub 2016 Jul 8.

Department of Cellular and Molecular Medicine, University of Ottawa Brain and Mind Research Institute, University of Ottawa, Ottawa, ON, Canada.

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http://dx.doi.org/10.1002/hipo.22613DOI Listing
November 2016

Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program.

Cell Stem Cell 2016 08 26;19(2):232-247. Epub 2016 May 26.

Department of Cellular and Molecular Medicine, University of Ottawa Brain and Mind Research Institute, Ottawa, ON K1H 8M5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.04.015DOI Listing
August 2016

Erratum to: Impaired mitochondrial oxidative phosphorylation and supercomplex assembly in rectus abdominis muscle of diabetic obese individuals.

Diabetologia 2016 Feb;59(2):396-7

Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Rd, Ottawa, ON, Canada, K1H 8M5.

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http://dx.doi.org/10.1007/s00125-015-3821-3DOI Listing
February 2016

Forebrain neurogenesis: From embryo to adult.

Trends Dev Biol 2016 Jan;9(1):77-90

Department of Biochemistry and Molecular Biology, Hotchkiss Brain Institute (HBI), Alberta Children's Hospital Research Institute (ACHRI), University of Calgary, Calgary, Alberta; Sunnybrook Research Institute, Biological Sciences, Toronto, Ontario, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373848PMC
January 2016

Impaired mitochondrial oxidative phosphorylation and supercomplex assembly in rectus abdominis muscle of diabetic obese individuals.

Diabetologia 2015 Dec 24;58(12):2861-6. Epub 2015 Sep 24.

Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Rd, Ottawa, ON, Canada, K1H 8M5.

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http://dx.doi.org/10.1007/s00125-015-3772-8DOI Listing
December 2015

Elevated Mitochondrial Bioenergetics and Axonal Arborization Size Are Key Contributors to the Vulnerability of Dopamine Neurons.

Curr Biol 2015 Sep 27;25(18):2349-60. Epub 2015 Aug 27.

Departments of Pharmacology and Neurosciences, Central Nervous System Research Group (GRSNC), Faculty of Medicine, Université de Montréal, Montréal, QC H4T 1J4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2015.07.050DOI Listing
September 2015

CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death.

Hum Mol Genet 2015 Aug 22;24(16):4573-83. Epub 2015 May 22.

Department of Cellular and Molecular Medicine, University of Ottawa Brain and Mind Research Institute, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada K1H 8M5,

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http://dx.doi.org/10.1093/hmg/ddv188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512627PMC
August 2015

Induction of protein deletion through in utero electroporation to define deficits in neuronal migration in transgenic models.

J Vis Exp 2015 Jan 12(95):51983. Epub 2015 Jan 12.

Department of Cellular and Molecular Medicine, University of Ottawa;

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http://dx.doi.org/10.3791/51983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354530PMC
January 2015

Regulation of ischemic neuronal death by E2F4-p130 protein complexes.

J Biol Chem 2014 Jun 14;289(26):18202-13. Epub 2014 May 14.

From the Department of Cellular and Molecular Medicine and Neuroscience, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada and

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http://www.jbc.org/lookup/doi/10.1074/jbc.M114.574145
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http://dx.doi.org/10.1074/jbc.M114.574145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140295PMC
June 2014

Regulation of the VHL/HIF-1 pathway by DJ-1.

J Neurosci 2014 Jun;34(23):8043-50

Department of Cellular and Molecular Medicine, Department of Cogno-Mechatronics Engineering, Pusan National University, Busan 609-735, Korea

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http://dx.doi.org/10.1523/JNEUROSCI.1244-13.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608259PMC
June 2014

Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival.

Nat Commun 2014 Apr 1;5:3550. Epub 2014 Apr 1.

Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.

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http://dx.doi.org/10.1038/ncomms4550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988820PMC
April 2014

LXCXE-independent chromatin remodeling by Rb/E2f mediates neuronal quiescence.

Cell Cycle 2013 May 9;12(9):1416-23. Epub 2013 Apr 9.

Department of Cellular & Molecular Medicine, University of Ottawa, Ottawa, ON, Canada.

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http://dx.doi.org/10.4161/cc.24527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674069PMC
May 2013

Opposing regulation of Sox2 by cell-cycle effectors E2f3a and E2f3b in neural stem cells.

Cell Stem Cell 2013 Apr 14;12(4):440-52. Epub 2013 Mar 14.

Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON K1H 8M5, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S19345909130005
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http://dx.doi.org/10.1016/j.stem.2013.02.001DOI Listing
April 2013

LKB1-regulated adaptive mechanisms are essential for neuronal survival following mitochondrial dysfunction.

Hum Mol Genet 2013 Mar 27;22(5):952-62. Epub 2012 Nov 27.

Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.

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http://dx.doi.org/10.1093/hmg/dds500DOI Listing
March 2013

ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons.

Hum Mol Genet 2012 Nov 7;21(22):4888-903. Epub 2012 Aug 7.

Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada.

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http://hmg.oxfordjournals.org/content/early/2012/08/22/hmg.d
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/dds325
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http://dx.doi.org/10.1093/hmg/dds325DOI Listing
November 2012

The retinoblastoma protein is essential for survival of postmitotic neurons.

J Neurosci 2012 Oct;32(42):14809-14

Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.

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http://dx.doi.org/10.1523/JNEUROSCI.1912-12.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621457PMC
October 2012

Guidelines for the use and interpretation of assays for monitoring autophagy.

Authors:
Daniel J Klionsky Fabio C Abdalla Hagai Abeliovich Robert T Abraham Abraham Acevedo-Arozena Khosrow Adeli Lotta Agholme Maria Agnello Patrizia Agostinis Julio A Aguirre-Ghiso Hyung Jun Ahn Ouardia Ait-Mohamed Slimane Ait-Si-Ali Takahiko Akematsu Shizuo Akira Hesham M Al-Younes Munir A Al-Zeer Matthew L Albert Roger L Albin Javier Alegre-Abarrategui Maria Francesca Aleo Mehrdad Alirezaei Alexandru Almasan Maylin Almonte-Becerril Atsuo Amano Ravi Amaravadi Shoba Amarnath Amal O Amer Nathalie Andrieu-Abadie Vellareddy Anantharam David K Ann Shailendra Anoopkumar-Dukie Hiroshi Aoki Nadezda Apostolova Giuseppe Arancia John P Aris Katsuhiko Asanuma Nana Y O Asare Hisashi Ashida Valerie Askanas David S Askew Patrick Auberger Misuzu Baba Steven K Backues Eric H Baehrecke Ben A Bahr Xue-Yuan Bai Yannick Bailly Robert Baiocchi Giulia Baldini Walter Balduini Andrea Ballabio Bruce A Bamber Edward T W Bampton Gábor Bánhegyi Clinton R Bartholomew Diane C Bassham Robert C Bast Henri Batoko Boon-Huat Bay Isabelle Beau Daniel M Béchet Thomas J Begley Christian Behl Christian Behrends Soumeya Bekri Bryan Bellaire Linda J Bendall Luca Benetti Laura Berliocchi Henri Bernardi Francesca Bernassola Sébastien Besteiro Ingrid Bhatia-Kissova Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Lawrence H Boise Paolo Bonaldo David L Boone Beat C Bornhauser Karina R Bortoluci Ioannis Bossis Frédéric Bost Jean-Pierre Bourquin Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan R Brady Claudio Brancolini Andreas Brech Jay E Brenman Ana Brennand Emery H Bresnick Patrick Brest Dave Bridges Molly L Bristol Paul S Brookes Eric J Brown John H Brumell Nicola Brunetti-Pierri Ulf T Brunk Dennis E Bulman Scott J Bultman Geert Bultynck Lena F Burbulla Wilfried Bursch Jonathan P Butchar Wanda Buzgariu Sergio P Bydlowski Ken Cadwell Monika Cahová Dongsheng Cai Jiyang Cai Qian Cai Bruno Calabretta Javier Calvo-Garrido Nadine Camougrand Michelangelo Campanella Jenny Campos-Salinas Eleonora Candi Lizhi Cao Allan B Caplan Simon R Carding Sandra M Cardoso Jennifer S Carew Cathleen R Carlin Virginie Carmignac Leticia A M Carneiro Serena Carra Rosario A Caruso Giorgio Casari Caty Casas Roberta Castino Eduardo Cebollero Francesco Cecconi Jean Celli Hassan Chaachouay Han-Jung Chae Chee-Yin Chai David C Chan Edmond Y Chan Raymond Chuen-Chung Chang Chi-Ming Che Ching-Chow Chen Guang-Chao Chen Guo-Qiang Chen Min Chen Quan Chen Steve S-L Chen WenLi Chen Xi Chen Xiangmei Chen Xiequn Chen Ye-Guang Chen Yingyu Chen Yongqiang Chen Yu-Jen Chen Zhixiang Chen Alan Cheng Christopher H K Cheng Yan Cheng Heesun Cheong Jae-Ho Cheong Sara Cherry Russ Chess-Williams Zelda H Cheung Eric Chevet Hui-Ling Chiang Roberto Chiarelli Tomoki Chiba Lih-Shen Chin Shih-Hwa Chiou Francis V Chisari Chi Hin Cho Dong-Hyung Cho Augustine M K Choi DooSeok Choi Kyeong Sook Choi Mary E Choi Salem Chouaib Divaker Choubey Vinay Choubey Charleen T Chu Tsung-Hsien Chuang Sheau-Huei Chueh Taehoon Chun Yong-Joon Chwae Mee-Len Chye Roberto Ciarcia Maria R Ciriolo Michael J Clague Robert S B Clark Peter G H Clarke Robert Clarke Patrice Codogno Hilary A Coller María I Colombo Sergio Comincini Maria Condello Fabrizio Condorelli Mark R Cookson Graham H Coombs Isabelle Coppens Ramon Corbalan Pascale Cossart Paola Costelli Safia Costes Ana Coto-Montes Eduardo Couve Fraser P Coxon James M Cregg José L Crespo Marianne J Cronjé Ana Maria Cuervo Joseph J Cullen Mark J Czaja Marcello D'Amelio Arlette Darfeuille-Michaud Lester M Davids Faith E Davies Massimo De Felici John F de Groot Cornelis A M de Haan Luisa De Martino Angelo De Milito Vincenzo De Tata Jayanta Debnath Alexei Degterev Benjamin Dehay Lea M D Delbridge Francesca Demarchi Yi Zhen Deng Jörn Dengjel Paul Dent Donna Denton Vojo Deretic Shyamal D Desai Rodney J Devenish Mario Di Gioacchino Gilbert Di Paolo Chiara Di Pietro Guillermo Díaz-Araya Inés Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Ivan Dikic Savithramma P Dinesh-Kumar Wen-Xing Ding Clark W Distelhorst Abhinav Diwan Mojgan Djavaheri-Mergny Svetlana Dokudovskaya Zheng Dong Frank C Dorsey Victor Dosenko James J Dowling Stephen Doxsey Marlène Dreux Mark E Drew Qiuhong Duan Michel A Duchosal Karen Duff Isabelle Dugail Madeleine Durbeej Michael Duszenko Charles L Edelstein Aimee L Edinger Gustavo Egea Ludwig Eichinger N Tony Eissa Suhendan Ekmekcioglu Wafik S El-Deiry Zvulun Elazar Mohamed Elgendy Lisa M Ellerby Kai Er Eng Anna-Mart Engelbrecht Simone Engelender Jekaterina Erenpreisa Ricardo Escalante Audrey Esclatine Eeva-Liisa Eskelinen Lucile Espert Virginia Espina Huizhou Fan Jia Fan Qi-Wen Fan Zhen Fan Shengyun Fang Yongqi Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Jean-Claude Farré Mathias Faure Marcus Fechheimer Carl G Feng Jian Feng Qili Feng Youji Feng László Fésüs Ralph Feuer Maria E Figueiredo-Pereira Gian Maria Fimia Diane C Fingar Steven Finkbeiner Toren Finkel Kim D Finley Filomena Fiorito Edward A Fisher Paul B Fisher Marc Flajolet Maria L Florez-McClure Salvatore Florio Edward A Fon Francesco Fornai Franco Fortunato Rati Fotedar Daniel H Fowler Howard S Fox Rodrigo Franco Lisa B Frankel Marc Fransen José M Fuentes Juan Fueyo Jun Fujii Kozo Fujisaki Eriko Fujita Mitsunori Fukuda Ruth H Furukawa Matthias Gaestel Philippe Gailly Malgorzata Gajewska Brigitte Galliot Vincent Galy Subramaniam Ganesh Barry Ganetzky Ian G Ganley Fen-Biao Gao George F Gao Jinming Gao Lorena Garcia Guillermo Garcia-Manero Mikel Garcia-Marcos Marjan Garmyn Andrei L Gartel Evelina Gatti Mathias Gautel Thomas R Gawriluk Matthew E Gegg Jiefei Geng Marc Germain Jason E Gestwicki David A Gewirtz Saeid Ghavami Pradipta Ghosh Anna M Giammarioli Alexandra N Giatromanolaki Spencer B Gibson Robert W Gilkerson Michael L Ginger Henry N Ginsberg Jakub Golab Michael S Goligorsky Pierre Golstein Candelaria Gomez-Manzano Ebru Goncu Céline Gongora Claudio D Gonzalez Ramon Gonzalez Cristina González-Estévez Rosa Ana González-Polo Elena Gonzalez-Rey Nikolai V Gorbunov Sharon Gorski Sandro Goruppi Roberta A Gottlieb Devrim Gozuacik Giovanna Elvira Granato Gary D Grant Kim N Green Aleš Gregorc Frédéric Gros Charles Grose Thomas W Grunt Philippe Gual Jun-Lin Guan Kun-Liang Guan Sylvie M Guichard Anna S Gukovskaya Ilya Gukovsky Jan Gunst Asa B Gustafsson Andrew J Halayko Amber N Hale Sandra K Halonen Maho Hamasaki Feng Han Ting Han Michael K Hancock Malene Hansen Hisashi Harada Masaru Harada Stefan E Hardt J Wade Harper Adrian L Harris James Harris Steven D Harris Makoto Hashimoto Jeffrey A Haspel Shin-ichiro Hayashi Lori A Hazelhurst Congcong He You-Wen He Marie-Joseé Hébert Kim A Heidenreich Miep H Helfrich Gudmundur V Helgason Elizabeth P Henske Brian Herman Paul K Herman Claudio Hetz Sabine Hilfiker Joseph A Hill Lynne J Hocking Paul Hofman Thomas G Hofmann Jörg Höhfeld Tessa L Holyoake Ming-Huang Hong David A Hood Gökhan S Hotamisligil Ewout J Houwerzijl Maria Høyer-Hansen Bingren Hu Chien-An A Hu Hong-Ming Hu Ya Hua Canhua Huang Ju Huang Shengbing Huang Wei-Pang Huang Tobias B Huber Won-Ki Huh Tai-Ho Hung Ted R Hupp Gang Min Hur James B Hurley Sabah N A Hussain Patrick J Hussey Jung Jin Hwang Seungmin Hwang Atsuhiro Ichihara Shirin Ilkhanizadeh Ken Inoki Takeshi Into Valentina Iovane Juan L Iovanna Nancy Y Ip Yoshitaka Isaka Hiroyuki Ishida Ciro Isidoro Ken-ichi Isobe Akiko Iwasaki Marta Izquierdo Yotaro Izumi Panu M Jaakkola Marja Jäättelä George R Jackson William T Jackson Bassam Janji Marina Jendrach Ju-Hong Jeon Eui-Bae Jeung Hong Jiang Hongchi Jiang Jean X Jiang Ming Jiang Qing Jiang Xuejun Jiang Xuejun Jiang Alberto Jiménez Meiyan Jin Shengkan Jin Cheol O Joe Terje Johansen Daniel E Johnson Gail V W Johnson Nicola L Jones Bertrand Joseph Suresh K Joseph Annie M Joubert Gábor Juhász Lucienne Juillerat-Jeanneret Chang Hwa Jung Yong-Keun Jung Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Motoni Kadowaki Katarina Kagedal Yoshiaki Kamada Vitaliy O Kaminskyy Harm H Kampinga Hiromitsu Kanamori Chanhee Kang Khong Bee Kang Kwang Il Kang Rui Kang Yoon-A Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Arthi Kanthasamy Vassiliki Karantza Gur P Kaushal Susmita Kaushik Yoshinori Kawazoe Po-Yuan Ke John H Kehrl Ameeta Kelekar Claus Kerkhoff David H Kessel Hany Khalil Jan A K W Kiel Amy A Kiger Akio Kihara Deok Ryong Kim Do-Hyung Kim Dong-Hou Kim Eun-Kyoung Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim John K Kim Peter K Kim Seong Who Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Jason S King Timothy J Kinsella Vladimir Kirkin Lorrie A Kirshenbaum Katsuhiko Kitamoto Kaio Kitazato Ludger Klein Walter T Klimecki Jochen Klucken Erwin Knecht Ben C B Ko Jan C Koch Hiroshi Koga Jae-Young Koh Young Ho Koh Masato Koike Masaaki Komatsu Eiki Kominami Hee Jeong Kong Wei-Jia Kong Viktor I Korolchuk Yaichiro Kotake Michael I Koukourakis Juan B Kouri Flores Attila L Kovács Claudine Kraft Dimitri Krainc Helmut Krämer Carole Kretz-Remy Anna M Krichevsky Guido Kroemer Rejko Krüger Oleg Krut Nicholas T Ktistakis Chia-Yi Kuan Roza Kucharczyk Ashok Kumar Raj Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Tino Kurz Ho Jeong Kwon Albert R La Spada Frank Lafont Trond Lamark Jacques Landry Jon D Lane Pierre Lapaquette Jocelyn F Laporte Lajos László Sergio Lavandero Josée N Lavoie Robert Layfield Pedro A Lazo Weidong Le Laurent Le Cam Daniel J Ledbetter Alvin J X Lee Byung-Wan Lee Gyun Min Lee Jongdae Lee Ju-Hyun Lee Michael Lee Myung-Shik Lee Sug Hyung Lee Christiaan Leeuwenburgh Patrick Legembre Renaud Legouis Michael Lehmann Huan-Yao Lei Qun-Ying Lei David A Leib José Leiro John J Lemasters Antoinette Lemoine Maciej S Lesniak Dina Lev Victor V Levenson Beth Levine Efrat Levy Faqiang Li Jun-Lin Li Lian Li Sheng Li Weijie Li Xue-Jun Li Yan-bo Li Yi-Ping Li Chengyu Liang Qiangrong Liang Yung-Feng Liao Pawel P Liberski Andrew Lieberman Hyunjung J Lim Kah-Leong Lim Kyu Lim Chiou-Feng Lin Fu-Cheng Lin Jian Lin Jiandie D Lin Kui Lin Wan-Wan Lin Weei-Chin Lin Yi-Ling Lin Rafael Linden Paul Lingor Jennifer Lippincott-Schwartz Michael P Lisanti Paloma B Liton Bo Liu Chun-Feng Liu Kaiyu Liu Leyuan Liu Qiong A Liu Wei Liu Young-Chau Liu Yule Liu Richard A Lockshin Chun-Nam Lok Sagar Lonial Benjamin Loos Gabriel Lopez-Berestein Carlos López-Otín Laura Lossi Michael T Lotze Peter Lőw Binfeng Lu Bingwei Lu Bo Lu Zhen Lu Frédéric Luciano Nicholas W Lukacs Anders H Lund Melinda A Lynch-Day Yong Ma Fernando Macian Jeff P MacKeigan Kay F Macleod Frank Madeo Luigi Maiuri Maria Chiara Maiuri Davide Malagoli May Christine V Malicdan Walter Malorni Na Man Eva-Maria Mandelkow Stéphen Manon Irena Manov Kai Mao Xiang Mao Zixu Mao Philippe Marambaud Daniela Marazziti Yves L Marcel Katie Marchbank Piero Marchetti Stefan J Marciniak Mateus Marcondes Mohsen Mardi Gabriella Marfe Guillermo Mariño Maria Markaki Mark R Marten Seamus J Martin Camille Martinand-Mari Wim Martinet Marta Martinez-Vicente Matilde Masini Paola Matarrese Saburo Matsuo Raffaele Matteoni Andreas Mayer Nathalie M Mazure David J McConkey Melanie J McConnell Catherine McDermott Christine McDonald Gerald M McInerney Sharon L McKenna BethAnn McLaughlin Pamela J McLean Christopher R McMaster G Angus McQuibban Alfred J Meijer Miriam H Meisler Alicia Meléndez Thomas J Melia Gerry Melino Maria A Mena Javier A Menendez Rubem F S Menna-Barreto Manoj B Menon Fiona M Menzies Carol A Mercer Adalberto Merighi Diane E Merry Stefania Meschini Christian G Meyer Thomas F Meyer Chao-Yu Miao Jun-Ying Miao Paul A M Michels Carine Michiels Dalibor Mijaljica Ana Milojkovic Saverio Minucci Clelia Miracco Cindy K Miranti Ioannis Mitroulis Keisuke Miyazawa Noboru Mizushima Baharia Mograbi Simin Mohseni Xavier Molero Bertrand Mollereau Faustino Mollinedo Takashi Momoi Iryna Monastyrska Martha M Monick Mervyn J Monteiro Michael N Moore Rodrigo Mora Kevin Moreau Paula I Moreira Yuji Moriyasu Jorge Moscat Serge Mostowy Jeremy C Mottram Tomasz Motyl Charbel E-H Moussa Sylke Müller Sylviane Muller Karl Münger Christian Münz Leon O Murphy Maureen E Murphy Antonio Musarò Indira Mysorekar Eiichiro Nagata Kazuhiro Nagata Aimable Nahimana Usha Nair Toshiyuki Nakagawa Kiichi Nakahira Hiroyasu Nakano Hitoshi Nakatogawa Meera Nanjundan Naweed I Naqvi Derek P Narendra Masashi Narita Miguel Navarro Steffan T Nawrocki Taras Y Nazarko Andriy Nemchenko Mihai G Netea Thomas P Neufeld Paul A Ney Ioannis P Nezis Huu Phuc Nguyen Daotai Nie Ichizo Nishino Corey Nislow Ralph A Nixon Takeshi Noda Angelika A Noegel Anna Nogalska Satoru Noguchi Lucia Notterpek Ivana Novak Tomoyoshi Nozaki Nobuyuki Nukina Thorsten Nürnberger Beat Nyfeler Keisuke Obara Terry D Oberley Salvatore Oddo Michinaga Ogawa Toya Ohashi Koji Okamoto Nancy L Oleinick F Javier Oliver Laura J Olsen Stefan Olsson Onya Opota Timothy F Osborne Gary K Ostrander Kinya Otsu Jing-hsiung James Ou Mireille Ouimet Michael Overholtzer Bulent Ozpolat Paolo Paganetti Ugo Pagnini Nicolas Pallet Glen E Palmer Camilla Palumbo Tianhong Pan 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Craig B Thompson Andrew Thorburn Michael Thumm FengFeng Tian Yuan Tian Glauco Tocchini-Valentini Aviva M Tolkovsky Yasuhiko Tomino Lars Tönges Sharon A Tooze Cathy Tournier John Tower Roberto Towns Vladimir Trajkovic Leonardo H Travassos Ting-Fen Tsai Mario P Tschan Takeshi Tsubata Allan Tsung Boris Turk Lorianne S Turner Suresh C Tyagi Yasuo Uchiyama Takashi Ueno Midori Umekawa Rika Umemiya-Shirafuji Vivek K Unni Maria I Vaccaro Enza Maria Valente Greet Van den Berghe Ida J van der Klei Wouter van Doorn Linda F van Dyk Marjolein van Egmond Leo A van Grunsven Peter Vandenabeele Wim P Vandenberghe Ilse Vanhorebeek Eva C Vaquero Guillermo Velasco Tibor Vellai Jose Miguel Vicencio Richard D Vierstra Miquel Vila Cécile Vindis Giampietro Viola Maria Teresa Viscomi Olga V Voitsekhovskaja Clarissa von Haefen Marcela Votruba Keiji Wada Richard Wade-Martins Cheryl L Walker Craig M Walsh Jochen Walter Xiang-Bo Wan Aimin Wang Chenguang Wang Dawei Wang Fan Wang Fen Wang Guanghui Wang Haichao Wang Hong-Gang Wang Horng-Dar Wang Jin Wang Ke Wang Mei Wang Richard C Wang Xinglong Wang Xuejun Wang Ying-Jan Wang Yipeng Wang Zhen Wang Zhigang Charles Wang Zhinong Wang Derick G Wansink Diane M Ward Hirotaka Watada Sarah L Waters Paul Webster Lixin Wei Conrad C Weihl William A Weiss Scott M Welford Long-Ping Wen Caroline A Whitehouse J Lindsay Whitton Alexander J Whitworth Tom Wileman John W Wiley Simon Wilkinson Dieter Willbold Roger L Williams Peter R Williamson Bradly G Wouters Chenghan Wu Dao-Cheng Wu William K K Wu Andreas Wyttenbach Ramnik J Xavier Zhijun Xi Pu Xia Gengfu Xiao Zhiping Xie Zhonglin Xie Da-zhi Xu Jianzhen Xu Liang Xu Xiaolei Xu Ai Yamamoto Akitsugu Yamamoto Shunhei Yamashina Michiaki Yamashita Xianghua Yan Mitsuhiro Yanagida Dun-Sheng Yang Elizabeth Yang Jin-Ming Yang Shi Yu Yang Wannian Yang Wei Yuan Yang Zhifen Yang Meng-Chao Yao Tso-Pang Yao Behzad Yeganeh Wei-Lien Yen Jia-jing Yin Xiao-Ming Yin Ook-Joon Yoo Gyesoon Yoon Seung-Yong Yoon Tomohiro Yorimitsu Yuko Yoshikawa Tamotsu Yoshimori Kohki Yoshimoto Ho Jin You Richard J Youle Anas Younes Li Yu Long Yu Seong-Woon Yu Wai Haung Yu Zhi-Min Yuan Zhenyu Yue Cheol-Heui Yun Michisuke Yuzaki Olga Zabirnyk Elaine Silva-Zacarin David Zacks Eldad Zacksenhaus Nadia Zaffaroni Zahra Zakeri Herbert J Zeh Scott O Zeitlin Hong Zhang Hui-Ling Zhang Jianhua Zhang Jing-Pu Zhang Lin Zhang Long Zhang Ming-Yong Zhang Xu Dong Zhang Mantong Zhao Yi-Fang Zhao Ying Zhao Zhizhuang J Zhao Xiaoxiang Zheng Boris Zhivotovsky Qing Zhong Cong-Zhao Zhou Changlian Zhu Wei-Guo Zhu Xiao-Feng Zhu Xiongwei Zhu Yuangang Zhu Teresa Zoladek Wei-Xing Zong Antonio Zorzano Jürgen Zschocke Brian Zuckerbraun

Autophagy 2012 Apr;8(4):445-544

Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.4161/auto.19496DOI Listing
April 2012

MCL-1 regulates the balance between autophagy and apoptosis.

Autophagy 2011 May 1;7(5):549-51. Epub 2011 May 1.

Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada.

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May 2011

The mitochondrial inner membrane GTPase, optic atrophy 1 (Opa1), restores mitochondrial morphology and promotes neuronal survival following excitotoxicity.

J Biol Chem 2011 Feb 1;286(6):4772-82. Epub 2010 Nov 1.

Department of Cellular and Molecular Medicine, University of Ottawa Heart Institute, University of Ottawa, Ontario K1H 8M5, Canada.

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February 2011

Rb/E2F regulates expression of neogenin during neuronal migration.

Mol Cell Biol 2011 Jan 8;31(2):238-47. Epub 2010 Nov 8.

Department of Cellular Molecular Medicine, University of Ottawa, 451 Smyth Rd., Ottawa, Ontario K1H 8M5, Canada.

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January 2011

Reactive oxygen species: stuck in the middle of neurodegeneration.

J Alzheimers Dis 2010 ;20 Suppl 2:S357-67

Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada.

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September 2010

The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death.

Nat Cell Biol 2010 Jun 16;12(6):563-71. Epub 2010 May 16.

Cellular Molecular Medicine, Ottawa Hospital Research Institute, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada K1H 8M5.

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June 2010

Sertad1 plays an essential role in developmental and pathological neuron death.

J Neurosci 2010 Mar;30(11):3973-82

Department of Pathology and Cell Biology and Taub Center for Alzheimer's Disease Research, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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March 2010

Mitochondria: joining forces to thwart cell death.

Biochim Biophys Acta 2010 Jan 10;1802(1):162-6. Epub 2009 Sep 10.

Faculty of Medicine, Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Rd., Ottawa, Ont. Canada K1H 8M5.

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January 2010

Pim-1 kinase as activator of the cell cycle pathway in neuronal death induced by DNA damage.

J Neurochem 2010 Jan 6;112(2):497-510. Epub 2009 Nov 6.

Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada.

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January 2010

Dining in with BCL-2: new guests at the autophagy table.

Clin Sci (Lond) 2009 Oct 26;118(3):173-81. Epub 2009 Oct 26.

Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada K1H 8M5.

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October 2009

The p107/E2F pathway regulates fibroblast growth factor 2 responsiveness in neural precursor cells.

Mol Cell Biol 2009 Sep 29;29(17):4701-13. Epub 2009 Jun 29.

University of Ottawa, Department of Cellular and Molecular Medicine, Ontario, Canada.

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September 2009

E2F4 is required for early eye patterning.

Dev Neurosci 2009 27;31(3):238-46. Epub 2009 Mar 27.

Department of Cellular and Molecular Medicine, University of Ottawa, Ont., Canada.

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July 2009

HES1 regulates 5-HT1A receptor gene transcription at a functional polymorphism: essential role in developmental expression.

Mol Cell Neurosci 2008 Jul 1;38(3):349-58. Epub 2008 Apr 1.

Ottawa Health Research Institute (Neuroscience) and Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON Canada.

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July 2008

Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage.

J Neurosci 2008 Jun;28(24):6068-78

Department of Biochemistry, Microbiology, and Immunology, Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada K1H 8M5.

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June 2008

Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP.

Proc Natl Acad Sci U S A 2008 Feb 24;105(5):1716-21. Epub 2008 Jan 24.

Ottawa Health Research Institute, Neuroscience Group, University of Ottawa, Ottawa, ON, Canada.

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February 2008

Required roles of Bax and JNKs in central and peripheral nervous system death of retinoblastoma-deficient mice.

J Biol Chem 2008 Jan 5;283(1):405-15. Epub 2007 Nov 5.

Department of Cellular Molecular Medicine, Neuroscience East, Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada.

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January 2008

Specific in vivo roles for E2Fs in differentiation and development.

Cell Cycle 2007 Dec 31;6(23):2917-27. Epub 2007 Aug 31.

Ottawa Health Research Institute, Department of Cellular & Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada.

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December 2007

The Parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage.

Proc Natl Acad Sci U S A 2007 Nov 14;104(47):18748-53. Epub 2007 Nov 14.

Ottawa Health Research Institute, Neuroscience Group, University of Ottawa, 451 Smyth Road, Ottawa, ON, Canada K1H 8M5.

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November 2007

The phosphorylation state of Drp1 determines cell fate.

EMBO Rep 2007 Oct;8(10):912-3

Ottawa Health Research Institute, Neuroscience Program, Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario K1H 8M5, Canada.

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October 2007

Mitofusin 2 protects cerebellar granule neurons against injury-induced cell death.

J Biol Chem 2007 Aug 30;282(33):23788-98. Epub 2007 May 30.

Department of Cellular and Molecular Medicine, University of Ottawa, Neurosciences Program, Ottawa Health Research Institute, Ottawa, Ontario K1H 8M5, Canada.

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August 2007

Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions.

Mol Cell Biol 2007 Jul 23;27(13):4825-43. Epub 2007 Apr 23.

Department of Cellular and Molecular Medicine, Ottawa Health Research Institute, University of Ottawa, Ottawa, ON, Canada.

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July 2007

The Retinoblastoma family member p107 regulates the rate of progenitor commitment to a neuronal fate.

J Cell Biol 2007 Jul 25;178(1):129-39. Epub 2007 Jun 25.

Department of Cellular and Molecular Medicine, Ottawa Health Research Institute, Neuroscience Program, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064429PMC
July 2007

Mitochondrial dynamics in the regulation of neuronal cell death.

Apoptosis 2007 May;12(5):979-92

University of Ottawa, Department of Cellular Molecular Medicine, Ottawa Health Research Institute, 451 Smyth Road, Ottawa, Ontario, Canada.

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May 2007

Cell cycle regulator E2F4 is essential for the development of the ventral telencephalon.

J Neurosci 2007 May;27(22):5926-35

Department of Cellular and Molecular Medicine, Ottawa Health Research Institute, Neuroscience Program, University of Ottawa, Ottawa, Ontario, Canada K1H 8M5.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672261PMC
May 2007

Urine concentrating defect in prostaglandin EP1-deficient mice.

Am J Physiol Renal Physiol 2007 Feb 1;292(2):F868-75. Epub 2006 Aug 1.

Department of Medicine, Ottawa Hospital, Ontario, Canada.

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February 2007

The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin.

J Neurosci 2006 Aug;26(34):8819-28

Ottawa Health Research Institute, Neuroscience Group, University of Ottawa, Ottawa, Ontario, Canada, K1H 8M5.

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http://dx.doi.org/10.1523/JNEUROSCI.2593-06.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6674376PMC
August 2006

Novel functions for cell cycle genes in nervous system development.

Cell Cycle 2006 Jul 17;5(14):1506-13. Epub 2006 Jul 17.

Ottawa Health Research Institute, Department of Cellular & Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada.

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July 2006

Regulation of axotomy-induced dopaminergic neuron death and c-Jun phosphorylation by targeted inhibition of cdc42 or mixed lineage kinase.

J Neurochem 2006 Jan 29;96(2):489-99. Epub 2005 Nov 29.

Neuroscience Research Institute, University of Ottawa and Ottawa Health Research Institute, Ottawa, Ontario, Canada.

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January 2006

Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death.

J Neurosci 2005 Sep;25(39):8954-66

Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa Health Research Institute, Ottawa, Ontario, K1H 8M5, Canada.

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http://dx.doi.org/10.1523/JNEUROSCI.2899-05.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6725602PMC
September 2005

Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms.

J Neurosci 2005 Feb;25(6):1324-34

Ottawa Health Research Institute, Neuroscience Center and Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada K1H 8M5.

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http://dx.doi.org/10.1523/JNEUROSCI.4261-04.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726004PMC
February 2005

p53 activation domain 1 is essential for PUMA upregulation and p53-mediated neuronal cell death.

J Neurosci 2004 Nov;24(44):10003-12

Ottawa Health Research Institute-Neuroscience Centre and Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, K1H 8M5 Canada.

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November 2004

p107 regulates neural precursor cells in the mammalian brain.

J Cell Biol 2004 Sep 7;166(6):853-63. Epub 2004 Sep 7.

Neuroscience Research Group, Ottawa Health Research Institute, Ottawa, Ontario, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172121PMC
September 2004

Emerging role for ERK as a key regulator of neuronal apoptosis.

Sci STKE 2004 Sep 14;2004(251):PE45. Epub 2004 Sep 14.

Ottawa Health Research Institute-Neuroscience Center and Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada K1H 8M5.

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http://dx.doi.org/10.1126/stke.2512004pe45DOI Listing
September 2004

The proapoptotic gene SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1.

J Biol Chem 2004 Jul 22;279(27):28706-14. Epub 2004 Apr 22.

Ottawa Health Research Institute, Neuroscience Centre and Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario K1H 8M5, Canada.

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July 2004

Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma.

Cancer Cell 2004 Jun;5(6):539-51

Toronto Western Research Institute, University Health Network, Vision Science Research Program, Department of Ophthalmology and Visual Sciences, University of Toronto, 399 Bathurst Street, Toronto, Ontario, Canada, M5T 2S8.

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http://dx.doi.org/10.1016/j.ccr.2004.05.025DOI Listing
June 2004

Role of AIF in caspase-dependent and caspase-independent cell death.

Oncogene 2004 Apr;23(16):2785-96

Department of Cellular and Molecular Medicine, Ottawa Health Research Institute, University of Ottawa, 451 Smyth Rd., Ottawa, Canada K1H 8M5.

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http://dx.doi.org/10.1038/sj.onc.1207517DOI Listing
April 2004

Nuclear factor-(kappa)B modulates the p53 response in neurons exposed to DNA damage.

J Neurosci 2004 Mar;24(12):2963-73

Ottawa Health Research Institute, Neurosciences, East Division, Ottawa, Ontario, Canada K1H 8M5.

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http://dx.doi.org/10.1523/JNEUROSCI.0155-04.2004DOI Listing
March 2004

Ataxia telangiectasia-mutated protein can regulate p53 and neuronal death independent of Chk2 in response to DNA damage.

J Biol Chem 2003 Sep 11;278(39):37782-9. Epub 2003 Jul 11.

Neuroscience Research Program of Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.

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September 2003

Calpains mediate p53 activation and neuronal death evoked by DNA damage.

J Biol Chem 2003 Jul 29;278(28):26031-8. Epub 2003 Apr 29.

Ottawa Health Research Institute, Neuroscience Group, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.

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http://dx.doi.org/10.1074/jbc.M302833200DOI Listing
July 2003

Growth factors: can they promote neurogenesis?

Trends Neurosci 2003 Jun;26(6):283-5

Ottawa Health Research Institute, University of Ottawa, 451 Smyth Road, K1H 8M5, Ottawa, ON, Canada.

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http://dx.doi.org/10.1016/S0166-2236(03)00100-0DOI Listing
June 2003

Interaction of the c-Jun/JNK pathway and cyclin-dependent kinases in death of embryonic cortical neurons evoked by DNA damage.

J Biol Chem 2002 Sep 28;277(38):35586-96. Epub 2002 Jun 28.

Neuroscience Research Institute, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.

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http://dx.doi.org/10.1074/jbc.M204362200DOI Listing
September 2002

Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death.

J Cell Biol 2002 Aug 29;158(3):507-17. Epub 2002 Jul 29.

Ottawa Health Research Institute, Department of Neuroscience, University of Ottawa, Ontario, Canada, K1H 8M5.

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http://dx.doi.org/10.1083/jcb.200202130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173837PMC
August 2002

Caspase 3 activity is required for skeletal muscle differentiation.

Proc Natl Acad Sci U S A 2002 Aug 12;99(17):11025-30. Epub 2002 Aug 12.

Ottawa Health Research Institute, Molecular Medicine Program, Ottawa General Hospital, Ottawa, ON, Canada K1H 8L6.

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http://dx.doi.org/10.1073/pnas.162172899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC123204PMC
August 2002