Ruth J Mayer

Ruth J Mayer

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Ruth J Mayer

Ruth J Mayer

Publications by authors named "Ruth J Mayer"

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13Publications

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Epithelial desquamation observed in a phase I study of an oral cathepsin C inhibitor (GSK2793660).

Br J Clin Pharmacol 2017 12 20;83(12):2813-2820. Epub 2017 Sep 20.

Respiratory Therapy Area Unit, GSK R&D, King of Prussia, Pennsylvania, USA.

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http://dx.doi.org/10.1111/bcp.13398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698569PMC
December 2017

Mechanisms of Vascular Dysfunction in COPD and Effects of a Novel Soluble Epoxide Hydrolase Inhibitor in Smokers.

Chest 2017 Mar 21;151(3):555-563. Epub 2016 Nov 21.

Experimental Medicine and Immunotherapeutics (EMIT), University of Cambridge, Addenbrooke's Hospital, Cambridge, England; Cambridge Clinical Trials Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, England.

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http://dx.doi.org/10.1016/j.chest.2016.10.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332206PMC
March 2017

Pharmacokinetics, pharmacodynamics and adverse event profile of GSK2256294, a novel soluble epoxide hydrolase inhibitor.

Br J Clin Pharmacol 2016 May 17;81(5):971-9. Epub 2016 Jan 17.

Experimental Medicine & Immunotherapeutics, Department of Medicine, University of Cambridge, and Cambridge Clinical Trials Unit, Cambridge.

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http://dx.doi.org/10.1111/bcp.12855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834590PMC
May 2016

Gene expression changes caused by the p38 MAPK inhibitor dilmapimod in COPD patients: analysis of blood and sputum samples from a randomized, placebo-controlled clinical trial.

Pharmacol Res Perspect 2015 Feb 9;3(1):e00094. Epub 2014 Dec 9.

University of Manchester, Medicines Evaluation Unit, University Hospital of South Manchester Foundations Trust Manchester, United Kingdom.

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http://dx.doi.org/10.1002/prp2.94DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317226PMC
February 2015

Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype.

PLoS One 2012 18;7(5):e37483. Epub 2012 May 18.

Thorax Institute, Hospital Clinic, Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona and Centro de investigación en red de enfermedades respiratorias (CIBERES), Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0037483PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356313PMC
September 2012

Different mitogen-activated protein kinase-dependent cytokine responses in cells of the monocyte lineage.

J Pharmacol Exp Ther 2008 Jan 5;324(1):306-12. Epub 2007 Oct 5.

Airway Disease Section, Guy Scadding Building, National Heart and Lung Institute, Imperial College London, Dovehouse St., London SW3 6LY, UK.

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http://dx.doi.org/10.1124/jpet.107.127670DOI Listing
January 2008