Ruth A Karron

Ruth A Karron

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Ruth A Karron

Ruth A Karron

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Meeting report: WHO consultation on Respiratory Syncytial Virus (RSV) vaccine development, Geneva, 25-26 April 2016.

Vaccine 2019 Nov 14;37(50):7355-7362. Epub 2017 Mar 14.

Initiative for Vaccine Research, World Health Organization, CH-1211 Geneva 27, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2017.02.068DOI Listing
November 2019

Safety and Immunogenicity of the Respiratory Syncytial Virus Vaccine RSV/ΔNS2/Δ1313/I1314L in RSV-Seronegative Children.

J Infect Dis 2019 Oct 12. Epub 2019 Oct 12.

RNA Viruses Section, Laboratory of Infectious Diseases, National Institute of Allergy, Immunology, and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1093/infdis/jiz408DOI Listing
October 2019

Hypergammaglobulinemia and Impaired Transplacental Transfer of Respiratory Syncytial Virus Antibody in Papua New Guinea.

Pediatr Infect Dis J 2019 09;38(9):e199-e202

From the Department of International, Center for Immunization Research, Health Johns Hopkins School of Public Health, Baltimore, Maryland.

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http://dx.doi.org/10.1097/INF.0000000000002364DOI Listing
September 2019

The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates.

Lancet Infect Dis 2018 10 18;18(10):e295-e311. Epub 2018 Jun 18.

Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht, Netherlands; Department of Paediatrics, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, Netherlands; Respiratory Syncytial Virus Network (ReSViNET) Foundation, Zeist, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(18)30292-5DOI Listing
October 2018

Evaluation of a Live Attenuated Human Metapneumovirus Vaccine in Adults and Children.

J Pediatric Infect Dis Soc 2018 Feb;7(1):86-89

Respiratory Viruses Section, Laboratory of Infectious Diseases, National Institute of Allergy, Immunology, and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1093/jpids/pix006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075531PMC
February 2018

The Advisory Committee on Immunization Practices recommendation regarding the use of live influenza vaccine: A rejoinder.

Vaccine 2018 01 3;36(3):343-344. Epub 2017 Jul 3.

Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X173079
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http://dx.doi.org/10.1016/j.vaccine.2017.06.017DOI Listing
January 2018

Determining the outcomes of interventions to prevent respiratory syncytial virus disease in children: what to measure?

Lancet Respir Med 2018 01 30;6(1):65-74. Epub 2017 Aug 30.

Department of Paediatrics and Child Heath, Red Cross War Memorial Children's Hospital, Cape Town, South Africa; Medical Research Council Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(17)30303-XDOI Listing
January 2018

Determining the burden of respiratory syncytial virus disease: the known and the unknown.

Lancet 2017 Sep 7;390(10098):917-918. Epub 2017 Jul 7.

Institute for International Programs, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(17)31476-9DOI Listing
September 2017

Report of the WHO technical consultation on the effect of maternal influenza and influenza vaccination on the developing fetus: Montreal, Canada, September 30-October 1, 2015.

Vaccine 2017 04 24;35(18):2279-2287. Epub 2017 Mar 24.

Departments of Epidemiology and Obstetrics and Gynecology, Brown University, 47 George Street, Providence, RI 02912, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2017.03.056DOI Listing
April 2017

Motavizumab, RSV, and subsequent wheezing - Authors' reply.

Lancet Infect Dis 2016 12 15;16(12):1329-1330. Epub 2016 Nov 15.

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1016/S1473-3099(16)30454-6DOI Listing
December 2016

Vaccination against respiratory syncytial virus in pregnancy.

Lancet Infect Dis 2016 12 15;16(12):1330-1331. Epub 2016 Nov 15.

Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/S1473-3099(16)30449-2DOI Listing
December 2016

Challenges and opportunities in RSV vaccine development: Meeting report from FDA/NIH workshop.

Vaccine 2016 09 25;34(41):4843-4849. Epub 2016 Aug 25.

Office of Vaccines Research and Review (OVRR), Center for Biologics Evaluation and Research (CBER), FDA, Silver Spring, MD, USA.

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http://dx.doi.org/10.1016/j.vaccine.2016.07.057DOI Listing
September 2016

Prevention and Control of Seasonal Influenza with Vaccines.

MMWR Recomm Rep 2016 Aug 26;65(5):1-54. Epub 2016 Aug 26.

Influenza Division, National Center for Immunization and Respiratory Diseases, CDC.

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http://dx.doi.org/10.15585/mmwr.rr6505a1DOI Listing
August 2016

The Impact of Respiratory Syncytial Virus Disease Prevention on Pediatric Asthma.

Pediatr Infect Dis J 2016 07;35(7):820-2

Fundación INFANT Buenos Aires, Argentina Centro Infant at Pontifícia Universidade Católica de Rio Grande do Sul Alegre, Brazil Johns Hopkins University Baltimore, Maryland Center for Asthma Research Vanderbilt University Nashville, Tennessee University of Colorado Denver and Center for Global Health Colorado School of Public Health Aurora, Colorado Centro Infant at Pontifícia Universidade Católica de Rio Grande do Sul Porto Alegre, Brazil Bill & Melinda Gates Foundation Seattle, Washigton Fundación INFANT, Buenos Aires, Argentina Department of Pediatrics Vanderbilt University Nashville, Tennessee.

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http://pdfs.journals.lww.com/pidj/2016/07000/The_Impact_of_R
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http://dx.doi.org/10.1097/INF.0000000000001167DOI Listing
July 2016

Evaluation of a Live-Attenuated Human Parainfluenza Type 1 Vaccine in Adults and Children.

J Pediatric Infect Dis Soc 2015 Dec 12;4(4):e143-6. Epub 2014 Nov 12.

Respiratory Viruses Section, Laboratory of Infectious Diseases, National Institute of Allergy, Immunology, and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

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https://academic.oup.com/jpids/article-lookup/doi/10.1093/jp
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http://dx.doi.org/10.1093/jpids/piu104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681387PMC
December 2015

A gene deletion that up-regulates viral gene expression yields an attenuated RSV vaccine with improved antibody responses in children.

Sci Transl Med 2015 Nov;7(312):312ra175

RNA Viruses Section, Laboratory of Infectious Diseases, National Institute of Allergy, Immunology, and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1126/scitranslmed.aac8463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342448PMC
November 2015

Evaluation of fast-track diagnostics and TaqMan array card real-time PCR assays for the detection of respiratory pathogens.

J Microbiol Methods 2014 Dec;107:222-6

International Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.mimet.2014.10.009DOI Listing
December 2014

Live-attenuated respiratory syncytial virus vaccines.

Curr Top Microbiol Immunol 2013 ;372:259-84

Center for Immunization Research, Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA,

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http://dx.doi.org/10.1007/978-3-642-38919-1_13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794267PMC
April 2014

Experimental infection of adults with recombinant wild-type human metapneumovirus.

J Infect Dis 2013 Nov 1;208(10):1669-78. Epub 2013 Aug 1.

Center for Immunization Research, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore.

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http://dx.doi.org/10.1093/infdis/jit356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805236PMC
November 2013

Attenuation of live respiratory syncytial virus vaccines is associated with reductions in levels of nasal cytokines.

J Infect Dis 2013 Jun 12;207(11):1773-9. Epub 2013 Mar 12.

Center for Immunization Research, Department of International Health, Johns Hopkins Bloomberg School of Public HealthBaltimore, Maryland, USA.

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http://dx.doi.org/10.1093/infdis/jit089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693589PMC
June 2013

Evaluation of two chimeric bovine-human parainfluenza virus type 3 vaccines in infants and young children.

Vaccine 2012 Jun 14;30(26):3975-81. Epub 2011 Dec 14.

Center for Immunization Research, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0264410X1101945
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http://dx.doi.org/10.1016/j.vaccine.2011.12.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509782PMC
June 2012

Evaluation of pneumonia virus of mice as a possible human pathogen.

J Virol 2012 May 21;86(10):5829-43. Epub 2012 Mar 21.

Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://jvi.asm.org/content/86/10/5829.full.pdf
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http://jvi.asm.org/content/early/2012/03/16/JVI.00163-12.ful
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http://jvi.asm.org/cgi/doi/10.1128/JVI.00163-12
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http://dx.doi.org/10.1128/JVI.00163-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347304PMC
May 2012

Disk diffusion bioassays for the detection of antibiotic activity in body fluids: applications for the Pneumonia Etiology Research for Child Health project.

Clin Infect Dis 2012 Apr;54 Suppl 2:S159-64

International Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health, 855 N. Wolfe St, Suite #600, Baltimore, MD 21205, USA.

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http://academic.oup.com/cid/article/54/suppl_2/S159/375361/D
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http://dx.doi.org/10.1093/cid/cir1061DOI Listing
April 2012

Specimen collection for the diagnosis of pediatric pneumonia.

Clin Infect Dis 2012 Apr;54 Suppl 2:S132-9

International Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1093/cid/cir1068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693496PMC
April 2012

Laboratory methods for determining pneumonia etiology in children.

Clin Infect Dis 2012 Apr;54 Suppl 2:S146-52

Department of Pathology, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1093/cid/cir1073DOI Listing
April 2012

Use and evaluation of molecular diagnostics for pneumonia etiology studies.

Clin Infect Dis 2012 Apr;54 Suppl 2:S153-8

Department of International Health, Johns Hopkins Bloomberg School of Public Health.

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http://dx.doi.org/10.1093/cid/cir1060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297547PMC
April 2012

Immune response following H1N1pdm09 vaccination: differences in antibody repertoire and avidity in young adults and elderly populations stratified by age and gender.

J Infect Dis 2012 Feb 29;205(4):610-20. Epub 2011 Dec 29.

Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/infdis/jir791DOI Listing
February 2012

Public health and biosecurity. The obligation to prevent the next dual-use controversy.

Science 2012 Feb 9;335(6070):802-4. Epub 2012 Feb 9.

Johns Hopkins Berman Institute of Bioethics, Johns Hopkins University, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1126/science.1219668DOI Listing
February 2012

The cDNA-derived investigational human parainfluenza virus type 3 vaccine rcp45 is well tolerated, infectious, and immunogenic in infants and young children.

Pediatr Infect Dis J 2011 Oct;30(10):e186-91

Center for Immunization Research, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1097/INF.0b013e31822ea24fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428040PMC
October 2011

Progress in the development of human parainfluenza virus vaccines.

Expert Rev Respir Med 2011 Aug;5(4):515-26

RNA Viruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1586/ers.11.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503243PMC
August 2011

An open label Phase I trial of a live attenuated H6N1 influenza virus vaccine in healthy adults.

Vaccine 2011 Apr 4;29(17):3144-8. Epub 2011 Mar 4.

Center for Immunization Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States.

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http://dx.doi.org/10.1016/j.vaccine.2011.02.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105354PMC
April 2011

Breathing new life into pneumonia diagnostics.

J Clin Microbiol 2009 Nov 9;47(11):3405-8. Epub 2009 Sep 9.

Department of Pathology, University of Otago, Christchurch, P.O. Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.1128/JCM.01685-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772647PMC
November 2009

Young infants can develop protective levels of neutralizing antibody after infection with respiratory syncytial virus.

J Infect Dis 2008 Oct;198(7):1007-15

Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1086/591460DOI Listing
October 2008

Social justice and disadvantaged groups.

Hastings Cent Rep 2007 Jul-Aug;37(4):32-9

Department of Health Policy and Management at the Johns Hopkins Bloomberg School of Public Health, USA.

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http://dx.doi.org/10.1353/hcr.2007.0064DOI Listing
November 2007

Identification of a recombinant live attenuated respiratory syncytial virus vaccine candidate that is highly attenuated in infants.

J Infect Dis 2005 Apr 1;191(7):1093-104. Epub 2005 Mar 1.

Center for Immunization Research, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1086/427813DOI Listing
April 2005

A bovine parainfluenza virus type 3 vaccine is safe and immunogenic in early infancy.

J Infect Dis 2005 Apr 22;191(7):1116-22. Epub 2005 Feb 22.

University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1086/428092DOI Listing
April 2005

rDEN4delta30, a live attenuated dengue virus type 4 vaccine candidate, is safe, immunogenic, and highly infectious in healthy adult volunteers.

J Infect Dis 2005 Mar 27;191(5):710-8. Epub 2005 Jan 27.

Center for Immunization Research, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1086/427780DOI Listing
March 2005

Anti-G protein antibody responses to respiratory syncytial virus infection or vaccination are associated with inhibition of G protein CX3C-CX3CR1 binding and leukocyte chemotaxis.

J Infect Dis 2004 Dec 28;190(11):1936-40. Epub 2004 Oct 28.

National Center for Infectious Diseases, Division of Viral and Rickettsial Diseases, Respiratory and Enteric Virus Branch, Atlanta, GA, USA.

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http://dx.doi.org/10.1086/425516DOI Listing
December 2004

The future of respiratory syncytial virus vaccine development.

Pediatr Infect Dis J 2004 Jan;23(1 Suppl):S65-73

Department of Intenational Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1097/01.inf.0000108194.71892.95DOI Listing
January 2004

Progress in the development of respiratory syncytial virus and parainfluenza virus vaccines.

Clin Infect Dis 2003 Dec 20;37(12):1668-77. Epub 2003 Nov 20.

Center for Immunization Research, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1086/379775DOI Listing
December 2003

Comparison of temple temperatures with rectal temperatures in children under two years of age.

Clin Pediatr (Phila) 2002 Jul-Aug;41(6):405-14

Department of Pediatrics, School of Medicine, The Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1177/000992280204100605DOI Listing
January 2003

A role for immune complexes in enhanced respiratory syncytial virus disease.

J Exp Med 2002 Sep;196(6):859-65

Department of Pediatrics, School of Medicine, Bloomberg School of Public Health at Johns Hopkins University, Baltimore, MD 21205, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194058PMC
http://dx.doi.org/10.1084/jem.20020781DOI Listing
September 2002

Respiratory syncytial virus infection in Navajo and White Mountain Apache children.

Pediatrics 2002 Aug;110(2 Pt 1):e20

Johns Hopkins University School of Medicine, Division of Pediatric Infectious Diseases, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1542/peds.110.2.e20DOI Listing
August 2002

Multiplex assay for detection of strain-specific antibodies against the two variable regions of the G protein of respiratory syncytial virus.

Clin Diagn Lab Immunol 2002 May;9(3):633-8

Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC119994PMC
http://dx.doi.org/10.1128/cdli.9.3.633-638.2002DOI Listing
May 2002

Risk factors for severe respiratory syncytial virus infection among Alaska native children.

Pediatrics 2002 Feb;109(2):210-6

Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, Alaska 99508, USA.

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http://dx.doi.org/10.1542/peds.109.2.210DOI Listing
February 2002