Russell L McLaughlin

Russell L McLaughlin

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Russell L McLaughlin

Russell L McLaughlin

Publications by authors named "Russell L McLaughlin"

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31Publications

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Lifetime Risk and Heritability of Amyotrophic Lateral Sclerosis.

JAMA Neurol 2019 Jul 22. Epub 2019 Jul 22.

Academic Unit of Neurology, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1001/jamaneurol.2019.2044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646974PMC
July 2019

Connectivity-based characterisation of subcortical grey matter pathology in frontotemporal dementia and ALS: a multimodal neuroimaging study.

Brain Imaging Behav 2018 Dec;12(6):1696-1707

Quantitative Neuroimaging Group, Academic Unit of Neurology, Biomedical Sciences Institute, Trinity College Dublin, Pearse Street, Dublin, Ireland.

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http://dx.doi.org/10.1007/s11682-018-9837-9DOI Listing
December 2018

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

Authors:
Aude Nicolas Kevin P Kenna Alan E Renton Nicola Ticozzi Faraz Faghri Ruth Chia Janice A Dominov Brendan J Kenna Mike A Nalls Pamela Keagle Alberto M Rivera Wouter van Rheenen Natalie A Murphy Joke J F A van Vugt Joshua T Geiger Rick A Van der Spek Hannah A Pliner Shankaracharya Bradley N Smith Giuseppe Marangi Simon D Topp Yevgeniya Abramzon Athina Soragia Gkazi John D Eicher Aoife Kenna Gabriele Mora Andrea Calvo Letizia Mazzini Nilo Riva Jessica Mandrioli Claudia Caponnetto Stefania Battistini Paolo Volanti Vincenzo La Bella Francesca L Conforti Giuseppe Borghero Sonia Messina Isabella L Simone Francesca Trojsi Fabrizio Salvi Francesco O Logullo Sandra D'Alfonso Lucia Corrado Margherita Capasso Luigi Ferrucci Cristiane de Araujo Martins Moreno Sitharthan Kamalakaran David B Goldstein Aaron D Gitler Tim Harris Richard M Myers Hemali Phatnani Rajeeva Lochan Musunuri Uday Shankar Evani Avinash Abhyankar Michael C Zody Julia Kaye Steven Finkbeiner Stacia K Wyman Alex LeNail Leandro Lima Ernest Fraenkel Clive N Svendsen Leslie M Thompson Jennifer E Van Eyk James D Berry Timothy M Miller Stephen J Kolb Merit Cudkowicz Emily Baxi Michael Benatar J Paul Taylor Evadnie Rampersaud Gang Wu Joanne Wuu Giuseppe Lauria Federico Verde Isabella Fogh Cinzia Tiloca Giacomo P Comi Gianni Sorarù Cristina Cereda Philippe Corcia Hannu Laaksovirta Liisa Myllykangas Lilja Jansson Miko Valori John Ealing Hisham Hamdalla Sara Rollinson Stuart Pickering-Brown Richard W Orrell Katie C Sidle Andrea Malaspina John Hardy Andrew B Singleton Janel O Johnson Sampath Arepalli Peter C Sapp Diane McKenna-Yasek Meraida Polak Seneshaw Asress Safa Al-Sarraj Andrew King Claire Troakes Caroline Vance Jacqueline de Belleroche Frank Baas Anneloor L M A Ten Asbroek José Luis Muñoz-Blanco Dena G Hernandez Jinhui Ding J Raphael Gibbs Sonja W Scholz Mary Kay Floeter Roy H Campbell Francesco Landi Robert Bowser Stefan M Pulst John M Ravits Daniel J L MacGowan Janine Kirby Erik P Pioro Roger Pamphlett James Broach Glenn Gerhard Travis L Dunckley Christopher B Brady Neil W Kowall Juan C Troncoso Isabelle Le Ber Kevin Mouzat Serge Lumbroso Terry D Heiman-Patterson Freya Kamel Ludo Van Den Bosch Robert H Baloh Tim M Strom Thomas Meitinger Aleksey Shatunov Kristel R Van Eijk Mamede de Carvalho Maarten Kooyman Bas Middelkoop Matthieu Moisse Russell L McLaughlin Michael A Van Es Markus Weber Kevin B Boylan Marka Van Blitterswijk Rosa Rademakers Karen E Morrison A Nazli Basak Jesús S Mora Vivian E Drory Pamela J Shaw Martin R Turner Kevin Talbot Orla Hardiman Kelly L Williams Jennifer A Fifita Garth A Nicholson Ian P Blair Guy A Rouleau Jesús Esteban-Pérez Alberto García-Redondo Ammar Al-Chalabi Ekaterina Rogaeva Lorne Zinman Lyle W Ostrow Nicholas J Maragakis Jeffrey D Rothstein Zachary Simmons Johnathan Cooper-Knock Alexis Brice Stephen A Goutman Eva L Feldman Summer B Gibson Franco Taroni Antonia Ratti Cinzia Gellera Philip Van Damme Wim Robberecht Pietro Fratta Mario Sabatelli Christian Lunetta Albert C Ludolph Peter M Andersen Jochen H Weishaupt William Camu John Q Trojanowski Vivianna M Van Deerlin Robert H Brown Leonard H van den Berg Jan H Veldink Matthew B Harms Jonathan D Glass David J Stone Pentti Tienari Vincenzo Silani Adriano Chiò Christopher E Shaw Bryan J Traynor John E Landers

Neuron 2018 03;97(6):1268-1283.e6

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867896PMC
March 2018

Insular Celtic population structure and genomic footprints of migration.

PLoS Genet 2018 01 25;14(1):e1007152. Epub 2018 Jan 25.

Complex Trait Genomics Laboratory, Smurfit Institute of Genetics, School of Genetics and Microbiology, Trinity College Dublin, College Green, Dublin, Republic of Ireland.

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http://dx.doi.org/10.1371/journal.pgen.1007152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784891PMC
January 2018

Neuroimaging patterns along the ALS-FTD spectrum: a multiparametric imaging study.

Amyotroph Lateral Scler Frontotemporal Degener 2017 11 31;18(7-8):611-623. Epub 2017 May 31.

a Quantitative Neuroimaging Group, Academic Unit of Neurology , Biomedical Sciences Institute, Trinity College Dublin , Dublin , Ireland.

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http://dx.doi.org/10.1080/21678421.2017.1332077DOI Listing
November 2017

The selective anatomical vulnerability of ALS: 'disease-defining' and 'disease-defying' brain regions.

Amyotroph Lateral Scler Frontotemporal Degener 2016 Oct - Nov;17(7-8):561-570. Epub 2016 Apr 18.

a Quantitative Neuroimaging Group, Academic Unit of Neurology , Biomedical Sciences Institute, Trinity College Dublin , Ireland.

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http://dx.doi.org/10.3109/21678421.2016.1173702DOI Listing
October 2017

Genetic testing in ALS: A survey of current practices.

Neurology 2017 Mar 3;88(10):991-999. Epub 2017 Feb 3.

From the Academic Unit of Neurology (A.V., R.L.M., M.H., O.T., O.H.), Trinity College Dublin; Cognitive Aging and Epidemiology Centre (S.A.), University of Edinburgh; and Institute of Psychiatry, Psychology and Neuroscience (A.A.-C.), King's College London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000003686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333513PMC
March 2017

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia.

Nat Commun 2017 03 21;8:14774. Epub 2017 Mar 21.

Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht 3584 CX, The Netherlands.

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http://dx.doi.org/10.1038/ncomms14774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364411PMC
March 2017

NEK1 variants confer susceptibility to amyotrophic lateral sclerosis.

Nat Genet 2016 09 25;48(9):1037-42. Epub 2016 Jul 25.

Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560030PMC
September 2016

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

Authors:
Wouter van Rheenen Aleksey Shatunov Annelot M Dekker Russell L McLaughlin Frank P Diekstra Sara L Pulit Rick A A van der Spek Urmo Võsa Simone de Jong Matthew R Robinson Jian Yang Isabella Fogh Perry Tc van Doormaal Gijs H P Tazelaar Max Koppers Anna M Blokhuis William Sproviero Ashley R Jones Kevin P Kenna Kristel R van Eijk Oliver Harschnitz Raymond D Schellevis William J Brands Jelena Medic Androniki Menelaou Alice Vajda Nicola Ticozzi Kuang Lin Boris Rogelj Katarina Vrabec Metka Ravnik-Glavač Blaž Koritnik Janez Zidar Lea Leonardis Leja Dolenc Grošelj Stéphanie Millecamps François Salachas Vincent Meininger Mamede de Carvalho Susana Pinto Jesus S Mora Ricardo Rojas-García Meraida Polak Siddharthan Chandran Shuna Colville Robert Swingler Karen E Morrison Pamela J Shaw John Hardy Richard W Orrell Alan Pittman Katie Sidle Pietro Fratta Andrea Malaspina Simon Topp Susanne Petri Susanne Abdulla Carsten Drepper Michael Sendtner Thomas Meyer Roel A Ophoff Kim A Staats Martina Wiedau-Pazos Catherine Lomen-Hoerth Vivianna M Van Deerlin John Q Trojanowski Lauren Elman Leo McCluskey A Nazli Basak Ceren Tunca Hamid Hamzeiy Yesim Parman Thomas Meitinger Peter Lichtner Milena Radivojkov-Blagojevic Christian R Andres Cindy Maurel Gilbert Bensimon Bernhard Landwehrmeyer Alexis Brice Christine A M Payan Safaa Saker-Delye Alexandra Dürr Nicholas W Wood Lukas Tittmann Wolfgang Lieb Andre Franke Marcella Rietschel Sven Cichon Markus M Nöthen Philippe Amouyel Christophe Tzourio Jean-François Dartigues Andre G Uitterlinden Fernando Rivadeneira Karol Estrada Albert Hofman Charles Curtis Hylke M Blauw Anneke J van der Kooi Marianne de Visser An Goris Markus Weber Christopher E Shaw Bradley N Smith Orietta Pansarasa Cristina Cereda Roberto Del Bo Giacomo P Comi Sandra D'Alfonso Cinzia Bertolin Gianni Sorarù Letizia Mazzini Viviana Pensato Cinzia Gellera Cinzia Tiloca Antonia Ratti Andrea Calvo Cristina Moglia Maura Brunetti Simona Arcuti Rosa Capozzo Chiara Zecca Christian Lunetta Silvana Penco Nilo Riva Alessandro Padovani Massimiliano Filosto Bernard Muller Robbert Jan Stuit Ian Blair Katharine Zhang Emily P McCann Jennifer A Fifita Garth A Nicholson Dominic B Rowe Roger Pamphlett Matthew C Kiernan Julian Grosskreutz Otto W Witte Thomas Ringer Tino Prell Beatrice Stubendorff Ingo Kurth Christian A Hübner P Nigel Leigh Federico Casale Adriano Chio Ettore Beghi Elisabetta Pupillo Rosanna Tortelli Giancarlo Logroscino John Powell Albert C Ludolph Jochen H Weishaupt Wim Robberecht Philip Van Damme Lude Franke Tune H Pers Robert H Brown Jonathan D Glass John E Landers Orla Hardiman Peter M Andersen Philippe Corcia Patrick Vourc'h Vincenzo Silani Naomi R Wray Peter M Visscher Paul I W de Bakker Michael A van Es R Jeroen Pasterkamp Cathryn M Lewis Gerome Breen Ammar Al-Chalabi Leonard H van den Berg Jan H Veldink

Nat Genet 2016 09 25;48(9):1043-8. Epub 2016 Jul 25.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1038/ng.3622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556360PMC
September 2016

Homozygosity mapping in an Irish ALS case-control cohort describes local demographic phenomena and points towards potential recessive risk loci.

Genomics 2015 Apr 23;105(4):237-41. Epub 2015 Jan 23.

Academic Unit of Neurology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Pearse Street, Dublin 2, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.ygeno.2015.01.002DOI Listing
April 2015

Second-generation Irish genome-wide association study for amyotrophic lateral sclerosis.

Neurobiol Aging 2015 Feb 6;36(2):1221.e7-13. Epub 2014 Sep 6.

Academic Unit of Neurology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Republic of Ireland.

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.08.030DOI Listing
February 2015

A novel MYH7 Leu1453pro mutation resulting in Laing distal myopathy in an Irish family.

Neuromuscul Disord 2015 Feb 28;25(2):155-60. Epub 2014 Sep 28.

Department of Neurology, Cork University Hospital, Cork, Ireland.

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http://dx.doi.org/10.1016/j.nmd.2014.09.007DOI Listing
February 2015

Genome flux and stasis in a five millennium transect of European prehistory.

Nat Commun 2014 Oct 21;5:5257. Epub 2014 Oct 21.

1] School of Archaeology, University College Dublin, Belfield, Dublin 4, Ireland [2] Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland [3] Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland [4] Earth Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1038/ncomms6257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218962PMC
October 2014

Basal ganglia involvement in amyotrophic lateral sclerosis.

Neurology 2013 Dec 8;81(24):2107-15. Epub 2013 Nov 8.

From the Biomedical Sciences Institute (P.B., M.E., S.B., A.V., O.H.), and Smurfit Institute of Genetics (R.L.M., K.K., D.G.B.), Trinity College Dublin; and Department of Neuropsychology (N.P.), Beaumont Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1212/01.wnl.0000437313.80913.2cDOI Listing
December 2013

Multiparametric MRI study of ALS stratified for the C9orf72 genotype.

Neurology 2013 Jul 14;81(4):361-9. Epub 2013 Jun 14.

Trinity College Institute of Neuroscience-TCIN, Beaumont Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1212/WNL.0b013e31829c5eeeDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772833PMC
July 2013

Using reference databases of genetic variation to evaluate the potential pathogenicity of candidate disease variants.

Hum Mutat 2013 Jun 26;34(6):836-41. Epub 2013 Mar 26.

Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1002/humu.22303DOI Listing
June 2013