Ruslan Dorfman

Ruslan Dorfman

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Ruslan Dorfman

Ruslan Dorfman

Publications by authors named "Ruslan Dorfman"

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38Publications

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Disease Risk Assessment Using a Voronoi-Based Network Analysis of Genes and Variants Scores.

Front Genet 2017 7;8:29. Epub 2017 Mar 7.

Agent-Based Modelling Laboratory, York University Toronto, ON, Canada.

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http://dx.doi.org/10.3389/fgene.2017.00029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339255PMC
March 2017

Prevalence of meconium ileus marks the severity of mutations of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene.

Genet Med 2016 Apr 18;18(4):333-40. Epub 2015 Jun 18.

Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/gim.2015.79DOI Listing
April 2016

Proposed regulatory framework for direct-to-consumer genetic testing: diagnostics vs genetic screening.

Clin Chem 2014 Nov 18;60(11):1455-6. Epub 2014 Sep 18.

GeneYouIn Inc. Toronto, ON, Canada.

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http://www.clinchem.org/cgi/doi/10.1373/clinchem.2014.226993
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http://dx.doi.org/10.1373/clinchem.2014.226993DOI Listing
November 2014

Genetic dissection of photoreceptor subtype specification by the Drosophila melanogaster zinc finger proteins elbow and no ocelli.

PLoS Genet 2014 Mar 13;10(3):e1004210. Epub 2014 Mar 13.

Center for Developmental Genetics, Department of Biology, New York University, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953069PMC
March 2014

Reply to Just the facts, please.

Authors:
Ruslan Dorfman

Nat Biotechnol 2013 Dec;31(12):1076-7

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http://www.nature.com/articles/nbt.2772
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http://dx.doi.org/10.1038/nbt.2772DOI Listing
December 2013

Application of personalized medicine to chronic disease: a feasibility assessment.

Clin Transl Med 2013 Dec 18;2(1):16. Epub 2013 Dec 18.

Present Address: Geneyouin Inc, Maple, ON, Canada.

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http://dx.doi.org/10.1186/2001-1326-2-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878365PMC
December 2013

Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene.

Nat Genet 2013 Oct 25;45(10):1160-7. Epub 2013 Aug 25.

1] Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA. [2] Perdana University Graduate School of Medicine, Serdang, Malaysia. [3] McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1038/ng.2745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874936PMC
October 2013

Falling prices and unfair competition in consumer genomics.

Authors:
Ruslan Dorfman

Nat Biotechnol 2013 Sep;31(9):785-6

Geneyouin Inc., Maple, Ontario, Canada.

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http://dx.doi.org/10.1038/nbt.2693DOI Listing
September 2013

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

Nat Genet 2013 Jun 21;45(6):670-5. Epub 2013 Apr 21.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://petercroucher.com/wp-content/uploads/2013/10/51_Natur
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http://www.nature.com/doifinder/10.1038/ng.2616
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http://dx.doi.org/10.1038/ng.2616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667736PMC
June 2013

The cystic fibrosis gene: a molecular genetic perspective.

Cold Spring Harb Perspect Med 2013 Feb 1;3(2):a009472. Epub 2013 Feb 1.

The University of Hong Kong, Hong Kong, Special Administrative Region, China.

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http://perspectivesinmedicine.cshlp.org/lookup/doi/10.1101/c
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http://dx.doi.org/10.1101/cshperspect.a009472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552342PMC
February 2013

Role of cystic fibrosis transmembrane conductance regulator in patients with chronic sinopulmonary disease.

Chest 2012 Oct;142(4):996-1004

Department of Medicine, University of Toronto, Toronto, ON, Canada; Division of Respirology and Keenan Research Centre of Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada. Electronic address:

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http://linkinghub.elsevier.com/retrieve/pii/S001236921260570
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http://dx.doi.org/10.1378/chest.11-2543DOI Listing
October 2012

Comparing the American and European diagnostic guidelines for cystic fibrosis: same disease, different language?

Thorax 2012 Jul 15;67(7):618-24. Epub 2012 Apr 15.

School of Women's and Children's Health, Faculty of Medicine, University of New South Wales and Sydney Children's Hospital, Randwick, Sydney, Australia.

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http://thorax.bmj.com/lookup/doi/10.1136/thoraxjnl-2011-2014
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http://dx.doi.org/10.1136/thoraxjnl-2011-201454DOI Listing
July 2012

Modifier gene studies to identify new therapeutic targets in cystic fibrosis.

Authors:
Ruslan Dorfman

Curr Pharm Des 2012 ;18(5):674-82

Neuroscience and Mental Health Program, The Hospital for Sick Children, 555 University Av., Toronto, ON M5G 1X8, Canada.

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June 2012

'Sensing' the link between type 1 and type 2 diabetes.

Diabetes Metab Res Rev 2011 Nov;27(8):913-8

The Research Institute, Hospital For Sick Children, University of Toronto, Neuroscience and Mental Health Program, Toronto, ON M5G 1X8, Canada.

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http://dx.doi.org/10.1002/dmrr.1279DOI Listing
November 2011

Evaluation of the disease liability of CFTR variants.

Methods Mol Biol 2011 ;742:355-72

McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1007/978-1-61779-120-8_21DOI Listing
September 2011

Modulatory effect of the SLC9A3 gene on susceptibility to infections and pulmonary function in children with cystic fibrosis.

Pediatr Pulmonol 2011 Apr 21;46(4):385-92. Epub 2010 Oct 21.

Program in Genetics and Genome Biology, Hospital for Sick Children, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/ppul.21372
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http://dx.doi.org/10.1002/ppul.21372DOI Listing
April 2011

Type of CFTR mutation determines risk of pancreatitis in patients with cystic fibrosis.

Gastroenterology 2011 Jan 9;140(1):153-61. Epub 2010 Nov 9.

Physiology and Experimental Medicine, The Research Institute, Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1053/j.gastro.2010.09.046DOI Listing
January 2011

TLR5 as an anti-inflammatory target and modifier gene in cystic fibrosis.

J Immunol 2010 Dec 10;185(12):7731-8. Epub 2010 Nov 10.

Department of Paediatrics, BC Children's Hospital and Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.4049/jimmunol.1001513DOI Listing
December 2010

Normalization of obesity-associated insulin resistance through immunotherapy.

Nat Med 2009 Aug 26;15(8):921-9. Epub 2009 Jul 26.

Department of Pediatrics & Immunology, Research Institute, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/nm.2001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063199PMC
August 2009

Identifying genetic and environmental risk factors for chronic orofacial pain syndromes: human models.

J Orofac Pain 2004 ;18(4):311-7

University of Toronto Centre for the Study of Pain, Faculty of Dentistry, Toronto, Ontario, Canada.

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January 2005

Proximodistal subdivision of Drosophila legs and wings: the elbow-no ocelli gene complex.

Development 2004 Feb;131(4):767-74

European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1242/dev.00979DOI Listing
February 2004

Stripe provides cues synergizing with branchless to direct tracheal cell migration.

Dev Biol 2002 Dec;252(1):119-26

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1006/dbio.2002.0836DOI Listing
December 2002

Robustness of the BMP morphogen gradient in Drosophila embryonic patterning.

Nature 2002 Sep;419(6904):304-8

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

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http://www.nature.com/articles/nature01061
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http://dx.doi.org/10.1038/nature01061DOI Listing
September 2002

Elbow and Noc define a family of zinc finger proteins controlling morphogenesis of specific tracheal branches.

Development 2002 Aug;129(15):3585-96

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

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August 2002