Rupert Handgretinger

Rupert Handgretinger

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Rupert Handgretinger

Publications by authors named "Rupert Handgretinger"

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G-CSF administration prior to donor lymphocyte apheresis promotes anti-leukaemic effects in allogeneic HCT patients.

Br J Haematol 2019 Jul 27;186(1):60-71. Epub 2019 Mar 27.

Blood and Marrow Transplantation, Department of Medicine II, University Hospital Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1111/bjh.15881DOI Listing
July 2019

Fast enzymatic synthesis of n.c.a. 6-[ F]fluorodopamine (FDA) from n.c.a. 6-[ F]FDOPA and the fate of 6-FDOPA and 6-FDA in neuroblastoma and Caki-1 cells after their uptake.

J Labelled Comp Radiopharm 2019 May 14. Epub 2019 May 14.

Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1002/jlcr.3752DOI Listing
May 2019

CRISPR/Cas9-modified hematopoietic stem cells-present and future perspectives for stem cell transplantation.

Bone Marrow Transplant 2019 Mar 22. Epub 2019 Mar 22.

University Children's Hospital, Department of Pediatrics I, Hematology and Oncology, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1038/s41409-019-0510-8DOI Listing
March 2019

Favorable immune recovery and low rate of GvHD in children transplanted with partially T cell-depleted PBSC grafts.

Bone Marrow Transplant 2019 Jan 24;54(1):53-62. Epub 2018 May 24.

Department of General Pediatrics, Hematology/Oncology, University Children's Hospital, Tuebingen, 72076, Germany.

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http://dx.doi.org/10.1038/s41409-018-0212-7DOI Listing
January 2019

Gene correction of HBB mutations in CD34 hematopoietic stem cells using Cas9 mRNA and ssODN donors.

Mol Cell Pediatr 2018 Nov 14;5(1). Epub 2018 Nov 14.

Department of Pediatrics I, Pediatric Infectiology and Immunology, Translational Genomics and Gene Therapy in Pediatrics, University of Tuebingen, Tuebingen, Germany.

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https://molcellped.springeropen.com/articles/10.1186/s40348-
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http://dx.doi.org/10.1186/s40348-018-0086-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236008PMC
November 2018

Characterization of monocyte subtypes regarding their phenotype and development in the context of graft-versus-host disease.

Transpl Immunol 2018 10 12;50:48-54. Epub 2018 Jun 12.

Children's Hospital, University of Tuebingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.trim.2018.06.004DOI Listing
October 2018

Identification of fatal outcome in a childhood nasopharyngeal carcinoma patient by protein expression profiling.

Int J Oncol 2018 Oct 19;53(4):1721-1731. Epub 2018 Jul 19.

Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, Johannes Gutenberg University, D-55128 Mainz, Germany.

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http://dx.doi.org/10.3892/ijo.2018.4491DOI Listing
October 2018

Human T cells modulate myeloid-derived suppressor cells through a TNF-α-mediated mechanism.

Immunol Lett 2018 10 1;202:31-37. Epub 2018 Aug 1.

Department of Pediatrics I, University of Tuebingen, Tuebingen, Germany; Department of Pediatrics, Kinderklinik Muenchen Schwabing, Klinikum Schwabing, StKM GmbH und Klinikum rechts der Isar, Technical University of Munich, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.imlet.2018.07.010DOI Listing
October 2018

The age of stored erythrocytes influences methaemoglobin formation when circulated in a heart-lung machine model.

Blood Transfus 2018 07 25;16(4):343-347. Epub 2017 Jan 25.

Department of Thoracic and Cardiovascular Surgery, University Hospital Tüebingen, Germany.

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http://dx.doi.org/10.2450/2017.0185-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034775PMC
July 2018

Haploidentical Stem Cell Transplantation for Refractory/Relapsed Neuroblastoma.

Biol Blood Marrow Transplant 2018 05 4;24(5):1005-1012. Epub 2018 Jan 4.

Department of Pediatrics, Children's University Hospital, University of Tübingen, Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2017.12.805DOI Listing
May 2018

Association analysis between SUFU polymorphism rs17114808 and acute graft versus host disease after hematopoietic stem cell transplantation.

Bone Marrow Transplant 2018 04 12;53(4):377-382. Epub 2018 Jan 12.

Department of General Paediatrics, Haematology/Oncology, University Children's Hospital, 72076, Tübingen, Germany.

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http://dx.doi.org/10.1038/s41409-017-0059-3DOI Listing
April 2018

Emerging role of immunotherapy for childhood cancers.

Chin Clin Oncol 2018 Apr;7(2):14

Children's University Hospital, Department Hematology/Oncology, University of Tuebingen, Hoppe-Seyler-Strasse 1, Tuebingen, Germany.

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http://dx.doi.org/10.21037/cco.2018.04.06DOI Listing
April 2018

The potential role of γδ T cells after allogeneic HCT for leukemia.

Blood 2018 03 22;131(10):1063-1072. Epub 2018 Jan 22.

Department of Hematology/Oncology, Children's University Hospital, Tuebingen, Germany.

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http://dx.doi.org/10.1182/blood-2017-08-752162DOI Listing
March 2018

Expression of checkpoint molecules on myeloid-derived suppressor cells.

Immunol Lett 2017 12 4;192:1-6. Epub 2017 Oct 4.

Department of Pediatrics I, University of Tuebingen, 72076 Tuebingen, Germany; Roche Pharma Research & Early Development (pRED), Immunology, Inflammation and Infectious Diseases (I3) Discovery and Translational Area, Roche Innovation Center Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.imlet.2017.10.001DOI Listing
December 2017

Enzymatic characterization of novel arylsulfatase A variants using human arylsulfatase A-deficient immortalized mesenchymal stromal cells.

Hum Mutat 2017 11 6;38(11):1511-1520. Epub 2017 Sep 6.

Division of Pediatric Stem Cell Transplantation and Immunology, Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://doi.wiley.com/10.1002/humu.23306
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http://dx.doi.org/10.1002/humu.23306DOI Listing
November 2017

Expression of KIR2DS1 does not significantly contribute to NK cell cytotoxicity in HLA-C1/C2 heterozygous haplotype B donors.

Int Immunol 2017 11;29(9):423-429

Department of Pediatric Hematology and Oncology, University Children's Hospital, Eberhard Karls University, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1093/intimm/dxx052DOI Listing
November 2017

Efficacy, safety and feasibility of antifungal prophylaxis with posaconazole tablet in paediatric patients after haematopoietic stem cell transplantation.

J Cancer Res Clin Oncol 2017 Jul 3;143(7):1281-1292. Epub 2017 Mar 3.

Division of Infectious Diseases, Department of Internal Medicine II, University Medical Centre Würzburg, Oberdürrbacher Straße 6, 97080, Würzburg, Germany.

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http://dx.doi.org/10.1007/s00432-017-2369-7DOI Listing
July 2017

Immunotargeting relapsed or refractory precursor B-cell acute lymphoblastic leukemia - role of blinatumomab.

Onco Targets Ther 2017 19;10:3567-3578. Epub 2017 Jul 19.

Department of Pediatric Hematology and Oncology, University Children's Hospital, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.2147/OTT.S103470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530848PMC
July 2017

Haploidentical hematopoietic cell transplantation using in vitro T cell depleted grafts as salvage therapy in patients with disease relapse after prior allogeneic transplantation.

Ann Hematol 2017 May 28;96(5):817-827. Epub 2017 Feb 28.

Medizinische Klinik II für Onkologie, Hämatologie, Immunologie, Rheumatologie und Pulmologie, Universitätsklinikum Tübingen, Otfried Müller Str. 10, 72076, Tübingen, Germany.

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http://dx.doi.org/10.1007/s00277-017-2941-xDOI Listing
May 2017

Tumor-priming converts NK cells to memory-like NK cells.

Oncoimmunology 2017 18;6(6):e1317411. Epub 2017 Apr 18.

University Children´s Hospital, Dep. of Pediatric Hematology and Oncology, Eberhard Karls University, Tuebingen, Germany.

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http://dx.doi.org/10.1080/2162402X.2017.1317411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486172PMC
April 2017

mRNA-Mediated Gene Supplementation of Toll-Like Receptors as Treatment Strategy for Asthma In Vivo.

PLoS One 2016 21;11(4):e0154001. Epub 2016 Apr 21.

Department of Pediatrics I - Pediatric Infectiology and Immunology - Translational Genomics and Gene Therapy, University of Tübingen, Tübingen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0154001PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839613PMC
March 2017

Phase I/Phase II Study of Blinatumomab in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia.

J Clin Oncol 2016 12 31;34(36):4381-4389. Epub 2016 Oct 31.

Arend von Stackelberg, Charité Campus Virchow, Berlin; Gerhard Zugmaier, Amgen Research (Munich), Munich; Rupert Handgretinger, University of Tübingen, Tübingen; Peter Bader, Hospital for Children and Adolescents III, University of Frankfurt, Frankfurt; Paul Gerhardt Schlegel, University Children's Hospital Würzburg, Würzburg; Arndt Borkhardt, University of Düsseldorf Medical Faculty, Düsseldorf, Germany; Franco Locatelli, Ospedale Pediatrico Bambino Gesù, Rome, University of Pavia, Pavia; Carmelo Rizzari, San Gerardo Hospital, University of Milano-Bicocca, Monza; Chiara Messina, Clinica di Oncoematologia Pediatrica, Università degli Studi di Padova, Padova, Italy; Benoît Brethon, Hôpital Robert Debré, Service Hématologie-Immunologie Pédiatrique, Paris; Gérard Michel, Hôpital de la Timone, Marseille, France; Christian M. Zwaan, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, Netherlands; Tanya M. Trippett, Memorial Sloan Kettering Cancer Center, New York, NY; Maureen M. O'Brien, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Deepa Bhojwani, Children's Hospital of Los Angeles; Kuolung Hu and Min Zhu, Amgen, Thousand Oaks, CA; Susan R. Rheingold, Children's Hospital of Philadelphia, Philadelphia, PA; Todd Michael Cooper, Seattle Children's Hospital, Seattle, WA; Phillip Barnette, Primary Children's Medical Center, Salt Lake City, UT; Steven G. DuBois, Dana-Farber/Boston Children's Cancer and Blood Disorders Center and Harvard Medical School, Boston, MA; Lia Gore, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO; and James A. Whitlock, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada.

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http://ascopubs.org/doi/10.1200/JCO.2016.67.3301
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http://dx.doi.org/10.1200/JCO.2016.67.3301DOI Listing
December 2016

Arsenic trioxide potentiates the effectiveness of etoposide in Ewing sarcomas.

Int J Oncol 2016 Nov 21;49(5):2135-2146. Epub 2016 Sep 21.

Laboratory of Cell Biology, Department of Orthopaedic Surgery, Eberhard Karls University Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.3892/ijo.2016.3700DOI Listing
November 2016

Outcomes of pediatric identical living-donor liver and hematopoietic stem cell transplantation.

Pediatr Transplant 2016 Nov 30;20(7):888-897. Epub 2016 May 30.

Department of Pediatric Gastroenterology and Hepatology, University Hospital Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1111/petr.12725DOI Listing
November 2016

Improved selectivity of mIBG uptake into neuroblastoma cells in vitro and in vivo by inhibition of organic cation transporter 3 uptake using clinically approved corticosteroids.

Nucl Med Biol 2016 09 27;43(9):543-551. Epub 2016 May 27.

Eberhard Karls University, Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Tuebingen, Germany; Eberhard Karls University, Department of Radiology, Diagnostic and Interventional Radiology, Hoppe-Seyler-Str. 3, D-72076 Tuebingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.nucmedbio.2016.05.013DOI Listing
September 2016

Hoechst 33342 Staining Identifies the Progenitor Side Population in NOD.Cg-PrkdcscidIL2rgtmWjl/Sz Mice Harboring Pediatric Leukemias.

In Vivo 2015 Nov-Dec;29(6):661-9

Department of Pediatric Hematology and Oncology, University Children's Hospital, Eberhard Karls University, Tuebingen, Germany.

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August 2016

Enhanced binding of necrosis-targeting immunocytokine NHS-IL12 after local tumour irradiation in murine xenograft models.

Cancer Immunol Immunother 2016 08 4;65(8):1003-13. Epub 2016 Jul 4.

Department of General Pediatrics, Oncology/Hematology, Eberhard Karls University Tübingen, Hoppe-Seyler-Str. 1, 72076, Tübingen, Germany.

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http://dx.doi.org/10.1007/s00262-016-1863-0DOI Listing
August 2016

Nifurtimox reduces N-Myc expression and aerobic glycolysis in neuroblastoma.

Cancer Biol Ther 2015 15;16(9):1353-63. Epub 2015 Jul 15.

a University Hospital Tuebingen; Children's Hospital; Department I - General Pediatrics; Hematology/Oncology ; Tuebingen , Germany.

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http://www.tandfonline.com/doi/full/10.1080/15384047.2015.10
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http://dx.doi.org/10.1080/15384047.2015.1070987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622434PMC
July 2016

Collagen VII Half-Life at the Dermal-Epidermal Junction Zone: Implications for Mechanisms and Therapy of Genodermatoses.

J Invest Dermatol 2016 06 18;136(6):1116-1123. Epub 2016 Feb 18.

Department of Dermatology, Medical Center-University of Freiburg, 79104 Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.02.002DOI Listing
June 2016

Exploitation of natural killer cells for the treatment of acute leukemia.

Blood 2016 06 20;127(26):3341-9. Epub 2016 May 20.

Department of Pediatric Hematology and Oncology, University Children's Hospital, University of Tuebingen, Tuebingen, Germany; and Department of Pediatric Intensive Care, University Children's Hospital, Basel, Switzerland.

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http://dx.doi.org/10.1182/blood-2015-12-629055DOI Listing
June 2016

Enriched Bone Marrow Derived Disseminated Neuroblastoma Cells Can Be a Reliable Source for Gene Expression Studies-A Validation Study.

PLoS One 2015 11;10(9):e0137995. Epub 2015 Sep 11.

CCRI, Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, Vienna, Austria; Department of Pediatrics, Medical University of Vienna, Vienna, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137995PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567134PMC
May 2016

NKG2D Signaling Leads to NK Cell Mediated Lysis of Childhood AML.

J Immunol Res 2015 8;2015:473175. Epub 2015 Jul 8.

Department of Hematology and Oncology, University Children's Hospital Tübingen, University of Tübingen, Hoppe-Seyler-Straße 1, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1155/2015/473175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510257PMC
March 2016

Posaconazole plasma concentration in pediatric patients receiving antifungal prophylaxis after allogeneic hematopoietic stem cell transplantation.

Med Mycol 2016 Feb 18;54(2):128-37. Epub 2015 Oct 18.

University Hospital Tübingen, Children's Hospital, Department I - General Pediatrics, Hematology/Oncology, Hoppe-Seyler-Str.1, 72076 Tübingen, Germany Ludwig-Maximilians-University München, Dr. von Hauner'sches Kinderspital, Pediatric Hematology, Oncology and Stem Cell Transplantation, Lindwurmstrasse 4, 80337 Munich

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http://dx.doi.org/10.1093/mmy/myv087DOI Listing
February 2016

Targeting hedgehog signalling by arsenic trioxide reduces cell growth and induces apoptosis in rhabdomyosarcoma.

Int J Oncol 2016 Feb 15;48(2):801-12. Epub 2015 Dec 15.

Department of Haematology and Oncology, Children's Hospital, Eberhard Karls University Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.3892/ijo.2015.3293DOI Listing
February 2016

Ferritin as an early marker of graft rejection after allogeneic hematopoietic stem cell transplantation in pediatric patients.

Ann Hematol 2016 Jan 27;95(2):311-23. Epub 2015 Nov 27.

Department of Paediatric Hematology and Oncology, University Hospital Hamburg-Eppendorf, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.

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http://link.springer.com/content/pdf/10.1007%2Fs00277-015-25
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http://link.springer.com/10.1007/s00277-015-2560-3
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http://dx.doi.org/10.1007/s00277-015-2560-3DOI Listing
January 2016

Modified mRNA as a new therapeutic option for pediatric respiratory diseases and hemoglobinopathies.

Mol Cell Pediatr 2015 Dec 20;2(1):11. Epub 2015 Nov 20.

Department of Pediatrics I-Pediatric Infectiology and Immunology, Translational Genomics and Gene Therapy in Pediatrics, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1186/s40348-015-0022-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654728PMC
December 2015

Isolation and Ex Vivo Culture of Vδ1+CD4+γδ T Cells, an Extrathymic αβT-cell Progenitor.

J Vis Exp 2015 Dec 7(106):e53482. Epub 2015 Dec 7.

Deptartment of Hematology and Oncology, Children's University Hospital Tübingen;

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http://dx.doi.org/10.3791/53482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692788PMC
December 2015

Preemptive administration of human αβ T cell receptor-targeting monoclonal antibody GZ-αβTCR potently abrogates aggressive graft-versus-host disease in vivo.

Ann Hematol 2015 Nov 13;94(11):1907-19. Epub 2015 Aug 13.

Department of Pediatric Hematology and Oncology, University Children's Hospital Tübingen, Hoppe-Seyler Street 1, 72076, Tübingen, Germany.

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http://dx.doi.org/10.1007/s00277-015-2471-3DOI Listing
November 2015

Chronic graft-versus-host-disease in CD34(+)-humanized NSG mice is associated with human susceptibility HLA haplotypes for autoimmune disease.

J Autoimmun 2015 Aug 3;62:55-66. Epub 2015 Jul 3.

Department of General Pediatrics, Oncology/Hematology, Eberhard Karls University Tübingen, Hoppe-Seyler-Str. 1, 72076 Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2015.06.006DOI Listing
August 2015

Cytokine serum levels during post-transplant adverse events in 61 pediatric patients after hematopoietic stem cell transplantation.

BMC Cancer 2015 Aug 28;15:607. Epub 2015 Aug 28.

Department of Paediatric Hematology and Oncology, University Hospital Hamburg-Eppendorf, Center for Obstetrics and Paediatrics, Martinistraße 52, 20246, Hamburg, Germany.

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http://dx.doi.org/10.1186/s12885-015-1616-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552308PMC
August 2015

Simultaneous Resection of High-risk Liver Tumors and Pulmonary Metastases in Children.

Ann Surg 2015 Jul;262(1):e1-3

*Department of Pediatric Surgery and Pediatric Urology, University Children's Hospital of Tuebingen, Tuebingen, Germany †Department of Diagnostic and Interventional Radiology, University Hospital of Tuebingen, Tuebingen, Germany ‡Department of Pediatric Hematology and Oncology, University Children's Hospital of Tuebingen, Tuebingen, Germany §Department of Anesthesiology and Intensive Care Medicine, University Hospital of Tuebingen, Tuebingen, Germany ¶Department of Pediatric Cardiology, Pulmonology and Intensive Care, University Children's Hospital of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1097/SLA.0000000000001167DOI Listing
July 2015

Phagocytic activity of monocytes, their subpopulations and granulocytes during post-transplant adverse events after hematopoietic stem cell transplantation.

Immunobiology 2015 May 15;220(5):605-13. Epub 2014 Dec 15.

University Hospital Gießen, Children's Hospital, Dpt. Paediatric Cardiology, Uhlandstr., 35392 Gießen, Germany.

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http://dx.doi.org/10.1016/j.imbio.2014.12.002DOI Listing
May 2015

Patterns of monocyte subpopulations and their surface expression of HLA-DR during adverse events after hematopoietic stem cell transplantation.

Ann Hematol 2015 May 30;94(5):825-36. Epub 2014 Dec 30.

Department I-General Paediatrics, Hematology/Oncology, Children's Hospital, University Hospital Tuebingen, Hoppe-Seyler-Str.1, 72076, Tuebingen, Germany,

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http://link.springer.com/10.1007/s00277-014-2287-6
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http://dx.doi.org/10.1007/s00277-014-2287-6DOI Listing
May 2015

Will post-transplantation cell therapies for pediatric patients become standard of care?

Biol Blood Marrow Transplant 2015 Mar 23;21(3):402-11. Epub 2014 Jul 23.

Departments of Pediatrics and Microbiology, Immunology and Tropical Medicine, Children's National Health System and George Washington University, Division of Pediatric Hematology-Oncology, Washington, DC.

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https://linkinghub.elsevier.com/retrieve/pii/S10838791140044
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http://dx.doi.org/10.1016/j.bbmt.2014.07.018DOI Listing
March 2015

Adoptive T-cell therapy with hexon-specific Th1 cells as a treatment of refractory adenovirus infection after HSCT.

Blood 2015 Mar 23;125(12):1986-94. Epub 2015 Jan 23.

Department of Pediatric Hematology/Oncology, University Children's Hospital Tübingen, Tübingen, Germany; German Center for Infection Research, Ludwig Maximilians University Munich, Munich, Germany.

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http://dx.doi.org/10.1182/blood-2014-06-573725DOI Listing
March 2015

Human leukocyte antigen DR surface expression on CD14+ monocytes during adverse events after hematopoietic stem cell transplantation.

Ann Hematol 2015 Feb 13;94(2):265-73. Epub 2014 Aug 13.

Department I - General Paediatrics, Hematology/Oncology, University Children's Hospital Tübingen, Hoppe-Seyler-Str. 1, 72076, Tübingen, Germany,

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http://dx.doi.org/10.1007/s00277-014-2185-yDOI Listing
February 2015

Human Peripheral CD4(+) Vδ1(+) γδT Cells Can Develop into αβT Cells.

Front Immunol 2014 17;5:645. Epub 2014 Dec 17.

Department of Hematology and Oncology, University Children's Hospital, University of Tübingen , Tübingen , Germany.

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http://dx.doi.org/10.3389/fimmu.2014.00645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329445PMC
February 2015

Both mature KIR+ and immature KIR- NK cells control pediatric acute B-cell precursor leukemia in NOD.Cg-Prkdcscid IL2rgtmWjl/Sz mice.

Blood 2014 Dec 30;124(26):3914-23. Epub 2014 Oct 30.

University Children's Hospital, Department of Pediatric Hematology and Oncology, Eberhard Karls University, Tuebingen, Germany; University Children's Hospital, Department of Pediatric Intensive Care, Basel, Switzerland.

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http://dx.doi.org/10.1182/blood-2014-05-572743DOI Listing
December 2014

γδ T Cell-Mediated Antibody-Dependent Cellular Cytotoxicity with CD19 Antibodies Assessed by an Impedance-Based Label-Free Real-Time Cytotoxicity Assay.

Front Immunol 2014 2;5:618. Epub 2014 Dec 2.

Department of General Paediatrics, Oncology/Haematology, University Children's Hospital Tübingen , Tübingen , Germany ; Partner Site Tübingen, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ) , Tübingen , Germany.

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http://dx.doi.org/10.3389/fimmu.2014.00618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251440PMC
December 2014

How an accidental discovery paved the way for the treatment of complicated infantile haemangiomas.

Acta Paediatr 2014 Sep 7;103(9):896-7. Epub 2014 Jul 7.

Department of Haematology/Oncology and General Paediatrics, Children's University Hospital, Tuebingen, Germany.

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http://doi.wiley.com/10.1111/apa.12715
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http://dx.doi.org/10.1111/apa.12715DOI Listing
September 2014

HLA-haploidentical stem cell transplantation after removal of αβ+ T and B cells in children with nonmalignant disorders.

Blood 2014 Jul 28;124(5):822-6. Epub 2014 May 28.

Department of Pediatric Hematology and Oncology, Istituto di Ricovero e Cura a Carattere Scientifico Bambino Gesù Children's Hospital, Rome, Italy; Department of Pediatrics, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1182/blood-2014-03-563817DOI Listing
July 2014

Synthesis and biological effects of new hybrid compounds composed of benzylguanidines and the alkylating group of busulfan on neuroblastoma cells.

Bioorg Med Chem Lett 2014 Jun 18;24(12):2728-33. Epub 2014 Apr 18.

Institut für Organische Chemie, Albert-Ludwigs-Universität Freiburg, Albertstraße 21, D-79104 Freiburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X140037
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http://dx.doi.org/10.1016/j.bmcl.2014.04.030DOI Listing
June 2014

Phase I trial of a novel anti-GD2 monoclonal antibody, Hu14.18K322A, designed to decrease toxicity in children with refractory or recurrent neuroblastoma.

J Clin Oncol 2014 May 7;32(14):1445-52. Epub 2014 Apr 7.

Fariba Navid, Barry L. Shulkin, Robert A. Kaufman, Catherine A. Billups, Jianrong Wu, Wayne L. Furman, Lisa M. McGregor, and Victor M. Santana, St Jude Children's Research Hospital; Fariba Navid, Robert A. Kaufman, Wayne L. Furman, Lisa M. McGregor, and Victor M. Santana, College of Medicine, University of Tennessee Health Science Center; Jim A. Allay, Children's GMP, Memphis, TN; Paul M. Sondel, Jacek Gan, Paul Hutson, Songwon Seo, KyungMann Kim, Jacob Goldberg, Jacquelyn A. Hank, and Mario Otto, University of Wisconsin, Madison, WI; Raymond Barfield, Duke University Medical Center, Durham, NC; Stephen D. Gillies, Provenance Biopharmaceuticals, Carlisle, MA; and Rupert Handgretinger, University Children's Hospital, Tübingen, Germany.

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http://ascopubs.org/doi/10.1200/JCO.2013.50.4423
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http://dx.doi.org/10.1200/JCO.2013.50.4423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017710PMC
May 2014

A newborn with grouped facial skin lesions and subsequent seizures.

BMC Pediatr 2014 May 22;14:126. Epub 2014 May 22.

Department I - General Paediatrics, Hematology/Oncology, University Hospital Tuebingen, Children's Hospital, Hoppe-Seyler-Str,1, Tuebingen 72076, Germany.

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http://dx.doi.org/10.1186/1471-2431-14-126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041904PMC
May 2014