Publications by authors named "Ruo-Zhen Gong"

5 Publications

  • Page 1 of 1

HRCT and MRI findings in X-linked non-syndromic deafness patients with a POU3F4 mutation.

Int J Pediatr Otorhinolaryngol 2014 Oct 17;78(10):1756-62. Epub 2014 Aug 17.

Shandong Medical Imaging Research Institute, Shandong University, Jinan 250012, China.

Objective: The aim of this study was to analyze HRCT and MRI findings in patients with X-linked non-syndromic deafness and a POU3f4 mutation.

Methods: HRCT and MRI data of four patients (males, 2-19 years old) with a POU3f4 mutation were collected and a retrospective review was performed. Cochlea, internal auditory canal (IAC), vestibule, semicircular canals, vestibular aqueduct, nerve canals in the IAC fundus, stapes and cochlear nerve were evaluated on 2D images (multi-planner reformation, MPR) and cochlear foramen on 3D images (CT virtual endoscopy, CTVE). Ten cases with normal hearing subjected to CT and MR exams served as controls.

Results: Inner ear malformations were bilateral and symmetrical. Cochlear malformation was shown to consist of as a relatively normal outer coat shape, absence of a cochlear modilous, and a direct intercommunication between the IAC and cochlear inner cavity. The lateral portion of the IAC was dilated. A spiral cochlear inner cavity was observed with CTVE images versus a helical cochlear nerve foramen as seen in controls. The labyrinthine facial nerve canal and superior vestibular nerve canal were enlarged. The Bill's bar was hypertrophic and partially pneumatized. A thickened stapes footplate was present and a fissura ante fenestram was absent in seven ears examined. A column shaped stapes was observed in one ear.

Conclusions: The absence of a cochlear modilous with a dilated lateral IAC and thickened stapes footplate were the remarkable features observed with imaging these in X-linked non-syndromic deafness patients with a POU3F4 mutation. Preoperative recognition of the image features in these patients is important because it precludes stapedectomy and indicates the risks in the surgery of cochlear implantation including CSF gusher and electrode insertion into IAC.
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October 2014

A retrospective study of laparoscopic unilateral adrenalectomy for primary hyperaldosteronism caused by unilateral adrenal hyperplasia.

Int Urol Nephrol 2014 Jul 2;46(7):1283-8. Epub 2014 Feb 2.

Minimally Invasive Urology Center, East District of Provincial Hospital Affiliated to Shandong University, 9th Floor, Block C, No. 9677, East Jingshi Road, Jinan, 250014, People's Republic of China.

Objective: To evaluated the long-term outcomes of laparoscopic unilateral adrenalectomy for primary aldosteronism (PA) caused by unilateral adrenal hyperplasia (UAH).

Methods: One hundred and sixty-four patients who underwent laparoscopic unilateral adrenalectomy for UAH from January 2004 to December 2011 were entered in this retrospective analysis. Patients demographics, perioperative parameters, and follow-up results were recorded and analyzed statistically.

Results: All 164 cases suffered hypertension with biochemical evidence of hyperaldosteronism prior to operation. Hypokalemia was observed in 52/164 (37.14%) patients. UAH was proved by multi-slice computed tomography (MSCT). All operations were completed successfully without any conversions or complications. Postoperative pathology confirmed that 164 cases were cortical nodular hyperplasia, of which 4 cases coexist with medullary hyperplasia and 7 with micro-adenoma. At the median follow-up of 48 months, hypertension was cured in 88 (53.7%) patients, improved in 71 (43.3%) patients, and refractory in 5 (3.05%) patients. Hypokalemia and hyperaldosteronism were cured in all patients except re-elevation of blood pressure and plasma aldosterone in two patients 1 month after adrenalectomy.

Conclusions: As an underestimated subtype of PA, UAH is accepted gradually. Laparoscopic unilateral adrenalectomy is nowadays the preferred approach to treat patients with PA caused by UAH. When adrenal venous sampling is not allowed, high-resolution MSCT is a reliable test for lateralization of aldosterone hypersecretion in carefully selected patients and 97% had either cure or improvement in blood pressure control.
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July 2014

[Removable appliance and closed of central incisors: report of 48 cases].

Shanghai Kou Qiang Yi Xue 2012 Dec;21(6):700-4

Department of Pediatric Dentistry, Jinan Hospital of Stomatology, Jinan 250001, China.

Purpose: To evaluate the treatment effect of orthodontic traction on embedded and inverted maxillary bending central incisors.

Methods: Fifty-two embedded and inverted maxillary central incisors without-eruption ability in 48 cases were treated by combined orthodontic traction with surgical treatment after spiral CT positioning and expanding the space, the eruption situation, gingival-breaking time and teeth pulp vitality after treatment were recorded, and the treatment effect was evaluated.

Results: Forty-eight cases with 52 impacted upper central incisors were treated with surgical and closed orthodontic traction, successful results were achieved in 36 cases, accounting for 69.23%; 15 cases had improvement, accounting for 28.85%; 1 case failed, accounting for 1.9%. Pulp vitality tests were all normal and there was no root absorption and ankylosis.

Conclusions: Selecting appropriate cases, precise positioning with spiral CT, proper space expanding and rational application of removable traction appliance are the keys to successful treatment of impacted and inverted maxillary bending central incisors of children in mixed dentition.
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December 2012

[Clinical and computer technology aspects of jugular bulb diverticulum].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2005 Jul;40(7):542-4

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July 2005

[CT multiplan reconstruction images of disorder of stapes].

Zhonghua Er Bi Yan Hou Ke Za Zhi 2004 May;39(5):265-8

Shandong Province Medical Imaging Research Institute, Jinan 250021, China.

Objective: To evaluate the clinical application of multi-planar reformation (MPR) for the stapes with multi-slice spinal thin-section CT in the patients with disorder of stapes before prosthetic ossicular reconstruction and their impact on surgical decision.

Methods: Axial CT scanning of temporal bone was undergone in 50 volunteers. Multiplan reformatted images included coronal, sagittal and oblique MPR, were made. All the MPR images were compared with each other in order to show which one could reveal the whole structures of stapes better. The height of stapes was measured with the oblique MPR. CT findings were evaluated in 102 cases with disorder of stapes. Prosthetic ossicular reconstruction was made in 65 cases.

Results: The full stapes cannot be shown in axial, coronal and sagittal MPR images, however, it was shown in oblique MPR in all the cases. The highness of stapes was (3.3 +/- 0.4) mm in the abnormal group. There was chronic otitis media in 69 cases (90 ears) and congenital abnormalities of the stapes in 33 cases (47 ears) which included the dispart of incudostapedial joint in 5 cases (7 ears), defect of head and crus of stapes in 9 cases (13 ears), defect of one side of crus in 3 cases (4 ears) and absence of the oval window in 16 cases (23 ears).

Conclusions: Coronal and oblique MPR images from Axial Spiral CT Data are essential for the pre-operative planning of prosthetic ossicular reconstruction. The ship, structure or defect of stapes can be shown in the oblique MPR images. It is important for the patient to choose the type of operation.
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May 2004