Runjun D Kumar

Runjun D Kumar

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Runjun D Kumar

Runjun D Kumar

Publications by authors named "Runjun D Kumar"

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Prioritizing Potentially Druggable Mutations with dGene: An Annotation Tool for Cancer Genome Sequencing Data.

Authors:
Runjun D Kumar Li-Wei Chang Matthew J Ellis Ron Bose

PLoS One 2013 27;8(6):e67980. Epub 2013 Jun 27.

Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America ; Computational and Systems Biology Program, Division of Biology and Biomedical Sciences, Washington University in St. Louis, St. Louis, Missouri, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0067980PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694871PMC
October 2017

Analysis of somatic mutations across the kinome reveals loss-of-function mutations in multiple cancer types.

Authors:
Runjun D Kumar Ron Bose

Sci Rep 2017 07 25;7(1):6418. Epub 2017 Jul 25.

Division of Oncology, Department of Medicine, Washington University School of Medicine, 660S Euclid Ave, St. Louis, MO, 63110, USA.

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http://www.nature.com/articles/s41598-017-06366-x
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http://dx.doi.org/10.1038/s41598-017-06366-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527104PMC
July 2017

Unsupervised detection of cancer driver mutations with parsimony-guided learning.

Authors:
Runjun D Kumar S Joshua Swamidass Ron Bose

Nat Genet 2016 10 12;48(10):1288-94. Epub 2016 Sep 12.

Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1038/ng.3658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328615PMC
October 2016

Statistically identifying tumor suppressors and oncogenes from pan-cancer genome-sequencing data.

Authors:
Runjun D Kumar Adam C Searleman S Joshua Swamidass Obi L Griffith Ron Bose

Bioinformatics 2015 Nov 25;31(22):3561-8. Epub 2015 Jul 25.

Division of Oncology, Department of Medicine, Washington University School of Medicine.

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http://dx.doi.org/10.1093/bioinformatics/btv430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757952PMC
November 2015

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Authors:
Dan E Arking Sara L Pulit Lia Crotti Pim van der Harst Patricia B Munroe Tamara T Koopmann Nona Sotoodehnia Elizabeth J Rossin Michael Morley Xinchen Wang Andrew D Johnson Alicia Lundby Daníel F Gudbjartsson Peter A Noseworthy Mark Eijgelsheim Yuki Bradford Kirill V Tarasov Marcus Dörr Martina Müller-Nurasyid Annukka M Lahtinen Ilja M Nolte Albert Vernon Smith Joshua C Bis Aaron Isaacs Stephen J Newhouse Daniel S Evans Wendy S Post Daryl Waggott Leo-Pekka Lyytikäinen Andrew A Hicks Lewin Eisele David Ellinghaus Caroline Hayward Pau Navarro Sheila Ulivi Toshiko Tanaka David J Tester Stéphanie Chatel Stefan Gustafsson Meena Kumari Richard W Morris Åsa T Naluai Sandosh Padmanabhan Alexander Kluttig Bernhard Strohmer Andrie G Panayiotou Maria Torres Michael Knoflach Jaroslav A Hubacek Kamil Slowikowski Soumya Raychaudhuri Runjun D Kumar Tamara B Harris Lenore J Launer Alan R Shuldiner Alvaro Alonso Joel S Bader Georg Ehret Hailiang Huang W H Linda Kao James B Strait Peter W Macfarlane Morris Brown Mark J Caulfield Nilesh J Samani Florian Kronenberg Johann Willeit J Gustav Smith Karin H Greiser Henriette Meyer Zu Schwabedissen Karl Werdan Massimo Carella Leopoldo Zelante Susan R Heckbert Bruce M Psaty Jerome I Rotter Ivana Kolcic Ozren Polašek Alan F Wright Maura Griffin Mark J Daly David O Arnar Hilma Hólm Unnur Thorsteinsdottir Joshua C Denny Dan M Roden Rebecca L Zuvich Valur Emilsson Andrew S Plump Martin G Larson Christopher J O'Donnell Xiaoyan Yin Marco Bobbo Adamo P D'Adamo Annamaria Iorio Gianfranco Sinagra Angel Carracedo Steven R Cummings Michael A Nalls Antti Jula Kimmo K Kontula Annukka Marjamaa Lasse Oikarinen Markus Perola Kimmo Porthan Raimund Erbel Per Hoffmann Karl-Heinz Jöckel Hagen Kälsch Markus M Nöthen Marcel den Hoed Ruth J F Loos Dag S Thelle Christian Gieger Thomas Meitinger Siegfried Perz Annette Peters Hanna Prucha Moritz F Sinner Melanie Waldenberger Rudolf A de Boer Lude Franke Pieter A van der Vleuten Britt Maria Beckmann Eimo Martens Abdennasser Bardai Nynke Hofman Arthur A M Wilde Elijah R Behr Chrysoula Dalageorgou John R Giudicessi Argelia Medeiros-Domingo Julien Barc Florence Kyndt Vincent Probst Alice Ghidoni Roberto Insolia Robert M Hamilton Stephen W Scherer Jeffrey Brandimarto Kenneth Margulies Christine E Moravec Fabiola del Greco M Christian Fuchsberger Jeffrey R O'Connell Wai K Lee Graham C M Watt Harry Campbell Sarah H Wild Nour E El Mokhtari Norbert Frey Folkert W Asselbergs Irene Mateo Leach Gerjan Navis Maarten P van den Berg Dirk J van Veldhuisen Manolis Kellis Bouwe P Krijthe Oscar H Franco Albert Hofman Jan A Kors André G Uitterlinden Jacqueline C M Witteman Lyudmyla Kedenko Claudia Lamina Ben A Oostra Gonçalo R Abecasis Edward G Lakatta Antonella Mulas Marco Orrú David Schlessinger Manuela Uda Marcello R P Markus Uwe Völker Harold Snieder Timothy D Spector Johan Ärnlöv Lars Lind Johan Sundström Ann-Christine Syvänen Mika Kivimaki Mika Kähönen Nina Mononen Olli T Raitakari Jorma S Viikari Vera Adamkova Stefan Kiechl Maria Brion Andrew N Nicolaides Bernhard Paulweber Johannes Haerting Anna F Dominiczak Fredrik Nyberg Peter H Whincup Aroon D Hingorani Jean-Jacques Schott Connie R Bezzina Erik Ingelsson Luigi Ferrucci Paolo Gasparini James F Wilson Igor Rudan Andre Franke Thomas W Mühleisen Peter P Pramstaller Terho J Lehtimäki Andrew D Paterson Afshin Parsa Yongmei Liu Cornelia M van Duijn David S Siscovick Vilmundur Gudnason Yalda Jamshidi Veikko Salomaa Stephan B Felix Serena Sanna Marylyn D Ritchie Bruno H Stricker Kari Stefansson Laurie A Boyer Thomas P Cappola Jesper V Olsen Kasper Lage Peter J Schwartz Stefan Kääb Aravinda Chakravarti Michael J Ackerman Arne Pfeufer Paul I W de Bakker Christopher Newton-Cheh

Nat Genet 2014 Aug 22;46(8):826-36. Epub 2014 Jun 22.

1] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [3] Harvard Medical School, Boston, Massachusetts, USA. [4] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [5].

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http://dx.doi.org/10.1038/ng.3014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124521PMC
August 2014

DGIdb: mining the druggable genome.

Authors:
Malachi Griffith Obi L Griffith Adam C Coffman James V Weible Josh F McMichael Nicholas C Spies James Koval Indraniel Das Matthew B Callaway James M Eldred Christopher A Miller Janakiraman Subramanian Ramaswamy Govindan Runjun D Kumar Ron Bose Li Ding Jason R Walker David E Larson David J Dooling Scott M Smith Timothy J Ley Elaine R Mardis Richard K Wilson

Nat Methods 2013 Dec 13;10(12):1209-10. Epub 2013 Oct 13.

1] The Genome Institute, Washington University School of Medicine, St. Louis, Missouri, USA. [2] Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA. [3].

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http://dx.doi.org/10.1038/nmeth.2689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851581PMC
December 2013