Publications by authors named "Rudolf Waelchli"

12Publications

Design of Potent and Selective Covalent Inhibitors of Bruton's Tyrosine Kinase Targeting an Inactive Conformation.

ACS Med Chem Lett 2019 Oct 6;10(10):1467-1472. Epub 2019 Sep 6.

Global Discovery Chemistry, Autoimmunity, Transplantation & Inflammation, Chemical Biology & Therapeutics, and PK Sciences, Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002 Basel, Switzerland.

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http://dx.doi.org/10.1021/acsmedchemlett.9b00317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792172PMC
October 2019

Patterns of conceptus development and of progesterone concentrations in maternal blood preceding spontaneous early pregnancy failure in mares.

Reprod Fertil Dev 2018 Jul;30(8):1066-1076

Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada.

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http://dx.doi.org/10.1071/RD17336DOI Listing
July 2018

Morphology of twin and triplet equine conceptuses during weeks 3 and 4 of pregnancy.

Reprod Fertil Dev 2013 ;25(5):762-74

Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON N1G 2W1, Canada.

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http://dx.doi.org/10.1071/RD12067DOI Listing
January 2014

Biosynthesis of oestrogen by the early equine embryo proper.

Reprod Fertil Dev 2012 ;24(8):1071-8

Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON N1G2W1, Canada.

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http://dx.doi.org/10.1071/RD11275DOI Listing
April 2013

Relationship between the timing of prostaglandin-induced luteolysis and effects on the conceptus during early pregnancy in mares.

Reprod Fertil Dev 2012 ;24(3):411-24

Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON N1G 2W1, Canada.

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http://dx.doi.org/10.1071/RD11132DOI Listing
July 2012

Estrogen metabolism by the equine embryo proper during the fourth week of pregnancy.

Reproduction 2009 Dec 26;138(6):953-60. Epub 2009 Aug 26.

Department of Biomedical Sciences, University of Guelph, Guelph, Ontario, Canada N1G2W1.

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http://dx.doi.org/10.1530/REP-09-0235DOI Listing
December 2009

Pyrrolo-pyrimidones: a novel class of MK2 inhibitors with potent cellular activity.

Bioorg Med Chem Lett 2008 Dec 11;18(23):6142-6. Epub 2008 Oct 11.

Novartis Institutes for BioMedical Research, global Discovery Chemistry, WSJ-88.508, CH-4002 Basel, Switzerland.

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http://dx.doi.org/10.1016/j.bmcl.2008.10.039DOI Listing
December 2008

Electrolyte distribution and yolk sac morphology in frozen hydrated equine conceptuses during the second week of pregnancy.

Reprod Fertil Dev 2007 ;19(7):804-14

Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.

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http://dx.doi.org/10.1071/rd07050DOI Listing
January 2008

Desialylation of core type 1 O-glycan in the equine embryonic capsule coincides with immobilization of the conceptus in the uterus.

Carbohydr Res 2007 Jun 17;342(8):1110-5. Epub 2007 Feb 17.

Department of Chemistry, University of Guelph, Guelph, ON, Canada N1G 2W1.

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http://dx.doi.org/10.1016/j.carres.2007.02.016DOI Listing
June 2007

Design and preparation of 2-benzamido-pyrimidines as inhibitors of IKK.

Bioorg Med Chem Lett 2006 Jan 19;16(1):108-12. Epub 2005 Oct 19.

Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland.

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http://dx.doi.org/10.1016/j.bmcl.2005.09.035DOI Listing
January 2006

Novel CCR1 antagonists with oral activity in the mouse collagen induced arthritis.

Bioorg Med Chem Lett 2005 Dec 28;15(23):5160-4. Epub 2005 Sep 28.

Novartis Institutes for BioMedical Research, Global Discovery Chemistry, Autoimmunity and Transplantation, CH-4002 Basel, Switzerland.

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http://dx.doi.org/10.1016/j.bmcl.2005.08.057DOI Listing
December 2005

Estrogen metabolism in the equine conceptus and endometrium during early pregnancy in relation to estrogen concentrations in yolk-sac fluid.

Biol Reprod 2004 Oct 26;71(4):1120-7. Epub 2004 May 26.

Department of Biomedical Sciences, University of Guelph, Guelph, Ontario, Canada N1G2W1.

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http://dx.doi.org/10.1095/biolreprod.104.028712DOI Listing
October 2004