Rudolf S Fehrmann

Rudolf S N Fehrmann

UNVERIFIED PROFILE

Are you Rudolf S N Fehrmann?   Register this Author

Register author
Rudolf S Fehrmann

Rudolf S N Fehrmann

Publications by authors named "Rudolf S N Fehrmann"

42Publications

1397Reads

46Profile Views

1PubMed Central Citations

Serotonin and Dopamine Receptor Expression in Solid Tumours Including Rare Cancers.

Pathol Oncol Res 2019 Sep 2. Epub 2019 Sep 2.

Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Box 30.001, 9700 RB, Groningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12253-019-00734-wDOI Listing
September 2019

Consideration of breast cancer subtype in targeting the androgen receptor.

Pharmacol Ther 2019 Aug 8;200:135-147. Epub 2019 May 8.

Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01637258193007
Publisher Site
http://dx.doi.org/10.1016/j.pharmthera.2019.05.005DOI Listing
August 2019

Transcriptional regulators CITED2 and PU.1 cooperate in maintaining hematopoietic stem cells.

Exp Hematol 2019 May 13;73:38-49.e7. Epub 2019 Apr 13.

Department of Hematology, Cancer Research Center Groningen, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exphem.2019.03.003DOI Listing
May 2019

Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: protocol of a multicentre, open-label, parallel-group, phase II-III, randomised, superiority study (CAIRO6)

BMC Cancer 2019 04 25;19(1):390. Epub 2019 Apr 25.

Department of Surgery, Catharina Hospital, PO Box 1350, 5602 ZA, Eindhoven, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-019-5545-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485075PMC
April 2019

TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells.

Oncogene 2019 02 3;38(6):852-867. Epub 2018 Sep 3.

Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41388-018-0470-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367211PMC
February 2019

Quantitative proteomics analysis identifies MUC1 as an effect sensor of EGFR inhibition.

Oncogene 2019 02 10;38(9):1477-1488. Epub 2018 Oct 10.

Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713GZ, Groningen, Netherlands.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41388-018-0522-7
Publisher Site
http://dx.doi.org/10.1038/s41388-018-0522-7DOI Listing
February 2019

BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity.

Nat Commun 2019 01 9;10(1):100. Epub 2019 Jan 9.

Department of Medical Oncology, University Medical Center Groningen, Cancer Research Center Groningen, University of Groningen, Hanzeplein 1, 9713GZ, Groningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-018-07927-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327059PMC
January 2019

Considering the biology of late recurrences in selecting patients for extended endocrine therapy in breast cancer.

Cancer Treat Rev 2018 Nov 26;70:118-126. Epub 2018 Jul 26.

Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ctrv.2018.07.015DOI Listing
November 2018

Glypican 3 Overexpression across a Broad Spectrum of Tumor Types Discovered with Functional Genomic mRNA Profiling of a Large Cancer Database.

Am J Pathol 2018 09 21;188(9):1973-1981. Epub 2018 Jun 21.

Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2018.05.014DOI Listing
September 2018

Data-Driven prioritisation of antibody-drug conjugate targets in head and neck squamous cell carcinoma.

Oral Oncol 2018 05 27;80:33-39. Epub 2018 Mar 27.

University of Groningen, University Medical Center Groningen, Department of Medical Oncology, Groningen, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.oraloncology.2018.03.005DOI Listing
May 2018

Data-Driven Prioritization and Review of Targets for Molecular-Based Theranostic Approaches in Pancreatic Cancer.

J Nucl Med 2017 12 19;58(12):1899-1903. Epub 2017 Oct 19.

Department of Medical Oncology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands; and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.117.198440DOI Listing
December 2017

Theranostics Using Antibodies and Antibody-Related Therapeutics.

J Nucl Med 2017 09;58(Suppl 2):83S-90S

Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.116.186940DOI Listing
September 2017

Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer.

J Natl Cancer Inst 2017 01 13;109(1). Epub 2016 Oct 13.

Affiliations of authors: Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (RDB, MATMvV, EGEdV, CPS, RSNF); Department of Medical Oncology and Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium (CS, MJPG); Division of Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands (JBAGH).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djw192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284248PMC
January 2017

Identification of novel therapeutic targets in anaplastic thyroid carcinoma using functional genomic mRNA-profiling: Paving the way for new avenues?

Surgery 2017 01 16;161(1):202-211. Epub 2016 Nov 16.

Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.surg.2016.06.064DOI Listing
January 2017

Functional genomic mRNA profiling of a large cancer data base demonstrates mesothelin overexpression in a broad range of tumor types.

Oncotarget 2015 Sep;6(29):28164-72

University of Groningen, University Medical Center Groningen, Department of Medical Oncology, Groningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.4461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695051PMC
September 2015

Regulators of homologous recombination repair as novel targets for cancer treatment.

Front Genet 2015 20;6:96. Epub 2015 Mar 20.

Department of Medical Oncology, Cancer Research Center Groningen, University Medical Center Groningen, University of Groningen Groningen, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fgene.2015.00096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367534PMC
April 2015

Treatment with high-dose simvastatin inhibits geranylgeranylation in AML blast cells in a subset of AML patients.

Exp Hematol 2012 Mar 25;40(3):177-186.e6. Epub 2011 Nov 25.

Department of Hematology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exphem.2011.11.008DOI Listing
March 2012

MixupMapper: correcting sample mix-ups in genome-wide datasets increases power to detect small genetic effects.

Bioinformatics 2011 Aug 7;27(15):2104-11. Epub 2011 Jun 7.

Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btr323DOI Listing
August 2011

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

Authors:
Carl A Anderson Gabrielle Boucher Charlie W Lees Andre Franke Mauro D'Amato Kent D Taylor James C Lee Philippe Goyette Marcin Imielinski Anna Latiano Caroline Lagacé Regan Scott Leila Amininejad Suzannah Bumpstead Leonard Baidoo Robert N Baldassano Murray Barclay Theodore M Bayless Stephan Brand Carsten Büning Jean-Frédéric Colombel Lee A Denson Martine De Vos Marla Dubinsky Cathryn Edwards David Ellinghaus Rudolf S N Fehrmann James A B Floyd Timothy Florin Denis Franchimont Lude Franke Michel Georges Jürgen Glas Nicole L Glazer Stephen L Guthery Talin Haritunians Nicholas K Hayward Jean-Pierre Hugot Gilles Jobin Debby Laukens Ian Lawrance Marc Lémann Arie Levine Cecile Libioulle Edouard Louis Dermot P McGovern Monica Milla Grant W Montgomery Katherine I Morley Craig Mowat Aylwin Ng William Newman Roel A Ophoff Laura Papi Orazio Palmieri Laurent Peyrin-Biroulet Julián Panés Anne Phillips Natalie J Prescott Deborah D Proctor Rebecca Roberts Richard Russell Paul Rutgeerts Jeremy Sanderson Miquel Sans Philip Schumm Frank Seibold Yashoda Sharma Lisa A Simms Mark Seielstad A Hillary Steinhart Stephan R Targan Leonard H van den Berg Morten Vatn Hein Verspaget Thomas Walters Cisca Wijmenga David C Wilson Harm-Jan Westra Ramnik J Xavier Zhen Z Zhao Cyriel Y Ponsioen Vibeke Andersen Leif Torkvist Maria Gazouli Nicholas P Anagnou Tom H Karlsen Limas Kupcinskas Jurgita Sventoraityte John C Mansfield Subra Kugathasan Mark S Silverberg Jonas Halfvarson Jerome I Rotter Christopher G Mathew Anne M Griffiths Richard Gearry Tariq Ahmad Steven R Brant Mathias Chamaillard Jack Satsangi Judy H Cho Stefan Schreiber Mark J Daly Jeffrey C Barrett Miles Parkes Vito Annese Hakon Hakonarson Graham Radford-Smith Richard H Duerr Séverine Vermeire Rinse K Weersma John D Rioux

Nat Genet 2011 Mar 6;43(3):246-52. Epub 2011 Feb 6.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084597PMC
March 2011

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction.

Authors:
Nona Sotoodehnia Aaron Isaacs Paul I W de Bakker Marcus Dörr Christopher Newton-Cheh Ilja M Nolte Pim van der Harst Martina Müller Mark Eijgelsheim Alvaro Alonso Andrew A Hicks Sandosh Padmanabhan Caroline Hayward Albert Vernon Smith Ozren Polasek Steven Giovannone Jingyuan Fu Jared W Magnani Kristin D Marciante Arne Pfeufer Sina A Gharib Alexander Teumer Man Li Joshua C Bis Fernando Rivadeneira Thor Aspelund Anna Köttgen Toby Johnson Kenneth Rice Mark P S Sie Ying A Wang Norman Klopp Christian Fuchsberger Sarah H Wild Irene Mateo Leach Karol Estrada Uwe Völker Alan F Wright Folkert W Asselbergs Jiaxiang Qu Aravinda Chakravarti Moritz F Sinner Jan A Kors Astrid Petersmann Tamara B Harris Elsayed Z Soliman Patricia B Munroe Bruce M Psaty Ben A Oostra L Adrienne Cupples Siegfried Perz Rudolf A de Boer André G Uitterlinden Henry Völzke Timothy D Spector Fang-Yu Liu Eric Boerwinkle Anna F Dominiczak Jerome I Rotter Gé van Herpen Daniel Levy H-Erich Wichmann Wiek H van Gilst Jacqueline C M Witteman Heyo K Kroemer W H Linda Kao Susan R Heckbert Thomas Meitinger Albert Hofman Harry Campbell Aaron R Folsom Dirk J van Veldhuisen Christine Schwienbacher Christopher J O'Donnell Claudia Beu Volpato Mark J Caulfield John M Connell Lenore Launer Xiaowen Lu Lude Franke Rudolf S N Fehrmann Gerard te Meerman Harry J M Groen Rinse K Weersma Leonard H van den Berg Cisca Wijmenga Roel A Ophoff Gerjan Navis Igor Rudan Harold Snieder James F Wilson Peter P Pramstaller David S Siscovick Thomas J Wang Vilmundur Gudnason Cornelia M van Duijn Stephan B Felix Glenn I Fishman Yalda Jamshidi Bruno H Ch Stricker Nilesh J Samani Stefan Kääb Dan E Arking

Nat Genet 2010 Dec 14;42(12):1068-76. Epub 2010 Nov 14.

Division of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338195PMC
December 2010

Multiple common variants for celiac disease influencing immune gene expression.

Nat Genet 2010 Apr 28;42(4):295-302. Epub 2010 Feb 28.

Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847618PMC
April 2010

Evidence based selection of housekeeping genes.

PLoS One 2007 Sep 19;2(9):e898. Epub 2007 Sep 19.

Division of Pediatric Oncology/Hematology, Department of Pediatrics, Beatrix Children's Hospital, Groningen, The Netherlands.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000898PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976390PMC
September 2007

Profiling studies in ovarian cancer: a review.

Oncologist 2007 Aug;12(8):960-6

Department of Medical Oncology, University Medical Center Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/theoncologist.12-8-960DOI Listing
August 2007