Publications by authors named "Rudi Balling"

84Publications

Addressing the Increased Expectations of Nutrition.

Annu Rev Nutr 2019 08;39:v-vi

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http://dx.doi.org/10.1146/annurev-nu-39-190619-100001DOI Listing
August 2019

Connecting environmental exposure and neurodegeneration using cheminformatics and high resolution mass spectrometry: potential and challenges.

Environ Sci Process Impacts 2019 Sep;21(9):1426-1445

Environmental Cheminformatics Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 6 Avenue du Swing, L-4367 Belvaux, Luxembourg.

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http://dx.doi.org/10.1039/c9em00068bDOI Listing
September 2019

Genes associated with Parkinson's disease respond to increasing polychlorinated biphenyl levels in the blood of healthy females.

Environ Pollut 2019 Jul 8;250:107-117. Epub 2019 Apr 8.

Department of Toxicogenomics, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands, 6229, ER Maastricht, the Netherlands.

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http://dx.doi.org/10.1016/j.envpol.2019.04.005DOI Listing
July 2019

Workshop Report: Systems Genetics of Neurodegenerative Disease, a Summer School in Systems Medicine, 25th August-1st September 2017.

Front Genet 2019 5;10:29. Epub 2019 Feb 5.

Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, United States.

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http://dx.doi.org/10.3389/fgene.2019.00029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370622PMC
February 2019

Introduction.

Annu Rev Nutr 2018 08;38

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http://dx.doi.org/10.1146/annurev-nu-38-070218-100001DOI Listing
August 2018

Rare coding variants in genes encoding GABA receptors in genetic generalised epilepsies: an exome-based case-control study.

Authors:
Patrick May Simon Girard Merle Harrer Dheeraj R Bobbili Julian Schubert Stefan Wolking Felicitas Becker Pamela Lachance-Touchette Caroline Meloche Micheline Gravel Cristina E Niturad Julia Knaus Carolien De Kovel Mohamad Toliat Anne Polvi Michele Iacomino Rosa Guerrero-López Stéphanie Baulac Carla Marini Holger Thiele Janine Altmüller Kamel Jabbari Ann-Kathrin Ruppert Wiktor Jurkowski Dennis Lal Raffaella Rusconi Sandrine Cestèle Benedetta Terragni Ian D Coombs Christopher A Reid Pasquale Striano Hande Caglayan Auli Siren Kate Everett Rikke S Møller Helle Hjalgrim Hiltrud Muhle Ingo Helbig Wolfram S Kunz Yvonne G Weber Sarah Weckhuysen Peter De Jonghe Sanjay M Sisodiya Rima Nabbout Silvana Franceschetti Antonietta Coppola Maria S Vari Dorothée Kasteleijn-Nolst Trenité Betul Baykan Ugur Ozbek Nerses Bebek Karl M Klein Felix Rosenow Dang K Nguyen François Dubeau Lionel Carmant Anne Lortie Richard Desbiens Jean-François Clément Cécile Cieuta-Walti Graeme J Sills Pauls Auce Ben Francis Michael R Johnson Anthony G Marson Bianca Berghuis Josemir W Sander Andreja Avbersek Mark McCormack Gianpiero L Cavalleri Norman Delanty Chantal Depondt Martin Krenn Fritz Zimprich Sarah Peter Marina Nikanorova Robert Kraaij Jeroen van Rooij Rudi Balling M Arfan Ikram André G Uitterlinden Giuliano Avanzini Stephanie Schorge Steven Petrou Massimo Mantegazza Thomas Sander Eric LeGuern Jose M Serratosa Bobby P C Koeleman Aarno Palotie Anna-Elina Lehesjoki Michael Nothnagel Peter Nürnberg Snezana Maljevic Federico Zara Patrick Cossette Roland Krause Holger Lerche

Lancet Neurol 2018 08 17;17(8):699-708. Epub 2018 Jul 17.

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http://dx.doi.org/10.1016/S1474-4422(18)30215-1DOI Listing
August 2018

Rare variants in 2 German families with Alzheimer disease.

Neurol Genet 2018 Apr 21;4(2):e224. Epub 2018 Mar 21.

Luxembourg Centre for Systems Biomedicine (LCSB) (P.M., D.R.B., R.B., J.G.S.), University of Luxembourg, Esch-sur-Alzette; Department of Psychiatry and Psychotherapy (S.P., D.H., M.M., C.S., M.R.), Saarland University Hospital, Saarland University, Homburg; and Department of Psychiatry and Psychotherapy (A.K.), Klinikum Rechts der Isar, TU-Muenchen, Munich, Germany.

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http://dx.doi.org/10.1212/NXG.0000000000000224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863691PMC
April 2018

A roadmap towards personalized immunology.

NPJ Syst Biol Appl 2018 6;4. Epub 2018 Feb 6.

1Department of Infection and Immunity, Luxembourg Institute of Health (LIH), 29, rue Henri Koch, 4354 Esch-sur-Alzette, Luxembourg.

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http://dx.doi.org/10.1038/s41540-017-0045-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802799PMC
February 2018

Embryonic development of selectively vulnerable neurons in Parkinson's disease.

NPJ Parkinsons Dis 2017 26;3:21. Epub 2017 Jun 26.

Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 6 Avenue du Swing, Belvaux, L-4362 Luxembourg.

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http://dx.doi.org/10.1038/s41531-017-0022-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484687PMC
June 2017

The P4 Health Spectrum - A Predictive, Preventive, Personalized and Participatory Continuum for Promoting Healthspan.

Prog Cardiovasc Dis 2017 Mar - Apr;59(5):506-521. Epub 2016 Aug 18.

College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA; SARENA Clinic, Medical Center and Research Institute.

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http://dx.doi.org/10.1016/j.pcad.2016.08.002DOI Listing
June 2017

Similar α-Synuclein staining in the colon mucosa in patients with Parkinson's disease and controls.

Mov Disord 2016 10;31(10):1567-1570

Department of Gastroenterology, Centre Hospitalier de Luxembourg, Luxembourg-City, Luxembourg.

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http://dx.doi.org/10.1002/mds.26702DOI Listing
October 2016

Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice.

BMC Genomics 2016 Feb 27;17:143. Epub 2016 Feb 27.

Department of Infection Genetics, Helmholtz Centre for Infection Research, Braunschweig and University of Veterinary Medicine Hannover, Inhoffenstr.7, D-38124, Braunschweig, Hannover, Germany.

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http://dx.doi.org/10.1186/s12864-016-2483-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769537PMC
February 2016

Neurological Diseases from a Systems Medicine Point of View.

Methods Mol Biol 2016 ;1386:221-50

Luxembourg Centre for Systems Biomedicine (LCSB), Université du Luxembourg, 7, Avenue des Hauts-Fourneaux, L-4362, Esch-Belval, Luxembourg.

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http://dx.doi.org/10.1007/978-1-4939-3283-2_11DOI Listing
October 2016

The mouse brain metabolome: region-specific signatures and response to excitotoxic neuronal injury.

Am J Pathol 2015 Jun 28;185(6):1699-712. Epub 2015 Apr 28.

Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2015.02.016DOI Listing
June 2015

Platelet mitochondrial membrane potential in Parkinson's disease.

Ann Clin Transl Neurol 2015 Jan 11;2(1):67-73. Epub 2014 Dec 11.

Luxembourg Centre for Systems Biomedicine (LCSB) Esch-sur-Alzette, Luxembourg ; Centre Hospitalier de Luxembourg (CHL) Luxembourg City, Luxembourg.

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http://dx.doi.org/10.1002/acn3.151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301676PMC
January 2015

Critical transitions in chronic disease: transferring concepts from ecology to systems medicine.

Curr Opin Biotechnol 2015 Aug 10;34:48-55. Epub 2014 Dec 10.

Experimental Neurobiology Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Campus Belval, 7 Avenue des Hauts-Fourneaux, L-4362 Esch-sur-Alzette, Luxembourg. Electronic address:

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http://dx.doi.org/10.1016/j.copbio.2014.11.020DOI Listing
August 2015

The hallmarks of Parkinson's disease.

FEBS J 2013 Dec 10;280(23):5981-93. Epub 2013 Jun 10.

Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette, Luxembourg.

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http://dx.doi.org/10.1111/febs.12335DOI Listing
December 2013

PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells.

Mol Syst Biol 2012 ;8:624

Department of Infection Genetics, Helmholtz Centre for Infection Research (HZI), University of Veterinary Medicine Hannover, Braunschweig, Germany.

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http://dx.doi.org/10.1038/msb.2012.56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531908PMC
January 2013

Understanding complexity in neurodegenerative diseases: in silico reconstruction of emergence.

Front Physiol 2012 23;3:291. Epub 2012 Jul 23.

Luxembourg Centre for Systems Biomedicine, University of Luxembourg Esch-sur-Alzette, Luxembourg.

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http://dx.doi.org/10.3389/fphys.2012.00291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429063PMC
October 2012

The role of regulatory T cells in neurodegenerative diseases.

Wiley Interdiscip Rev Syst Biol Med 2013 Mar-Apr;5(2):153-80. Epub 2012 Aug 15.

Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Campus Belval, Luxembourg.

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http://doi.wiley.com/10.1002/wsbm.1187
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http://dx.doi.org/10.1002/wsbm.1187DOI Listing
July 2013

Revolutionizing medicine in the 21st century through systems approaches.

Biotechnol J 2012 Aug 20;7(8):992-1001. Epub 2012 Jul 20.

Institute for Systems Biology, 401 Terry Avenue North, Seattle, WA 98109-5234, USA.

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http://doi.wiley.com/10.1002/biot.201100306
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http://dx.doi.org/10.1002/biot.201100306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962497PMC
August 2012

From systems biology to systems biomedicine.

Curr Opin Biotechnol 2012 Aug 24;23(4):604-8. Epub 2011 Nov 24.

Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Luxembourg.

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http://dx.doi.org/10.1016/j.copbio.2011.11.009DOI Listing
August 2012

Emergence of the silicon human and network targeting drugs.

Eur J Pharm Sci 2012 Jul 16;46(4):190-7. Epub 2011 Jun 16.

Molecular Cell Physiology, VU University Amsterdam, de Boelelaan 1085, NL-1081 HV Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ejps.2011.06.006DOI Listing
July 2012

Parkinson's disease mouse models in translational research.

Mamm Genome 2011 Aug 11;22(7-8):401-19. Epub 2011 May 11.

Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Luxembourg.

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http://dx.doi.org/10.1007/s00335-011-9330-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151483PMC
August 2011

Diseases as network perturbations.

Curr Opin Biotechnol 2010 Aug 13;21(4):566-71. Epub 2010 Aug 13.

Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Luxembourg.

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https://linkinghub.elsevier.com/retrieve/pii/S09581669100012
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http://dx.doi.org/10.1016/j.copbio.2010.07.010DOI Listing
August 2010

A non-functioning vitamin D receptor predisposes to leukaemoid reactions in mice.

Hematol Oncol 2010 Dec;28(4):185-91

Institute of Animal Physiology, Ludwig Maximilians University, Veterinärstrasse, Munich, Germany.

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http://doi.wiley.com/10.1002/hon.938
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http://dx.doi.org/10.1002/hon.938DOI Listing
December 2010

Reverse engineering and verification of gene networks: principles, assumptions, and limitations of present methods and future perspectives.

J Biotechnol 2009 Nov 22;144(3):190-203. Epub 2009 Jul 22.

Helmholtz Centre for Infection Research, D-38124 Braunschweig, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S016816560900308
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http://dx.doi.org/10.1016/j.jbiotec.2009.07.013DOI Listing
November 2009

Sudden and unexpected.

Authors:
Rudi Balling

Nat Genet 2007 Dec;39(12):1422-3

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http://dx.doi.org/10.1038/ng1207-1422DOI Listing
December 2007

Dynamic cumulative activity of transcription factors as a mechanism of quantitative gene regulation.

Genome Biol 2007 ;8(9):R181

Biological Systems Analysis Group, HZI- Helmholtz Centre for Infection Research, Inhoffenstrasse, D-38124 Braunschweig, Germany.

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https://orbilu.uni.lu/bitstream/10993/911/1/Dynamic%20cumula
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http://genomebiology.com/2007/8/9/R181
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http://dx.doi.org/10.1186/gb-2007-8-9-r181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375019PMC
May 2008

From mouse genetics to systems biology.

Authors:
Rudi Balling

Mamm Genome 2007 Jul 1;18(6-7):383-8. Epub 2007 Aug 1.

Helmholtz Centre for Infection Research, Braunschweig, Germany.

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http://dx.doi.org/10.1007/s00335-007-9044-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1998886PMC
July 2007

1alpha,25-Dihydroxyvitamin D3 is a potent suppressor of interferon gamma-mediated macrophage activation.

Blood 2005 Dec 23;106(13):4351-8. Epub 2005 Aug 23.

Junior Research Group Infection Genetics, German Research Centre for Biotechnology, Mascheroder Weg 1, D-38124 Braunschweig, Germany.

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http://dx.doi.org/10.1182/blood-2005-03-1029DOI Listing
December 2005

Maintaining your immune system--one method for enhanced longevity.

Sci Aging Knowledge Environ 2004 Jan 7;2004(1):pe2. Epub 2004 Jan 7.

German Research Centre for Biotechnology, Mascheroder Weg 1, D-38124 Braunschweig, Germany.

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http://dx.doi.org/10.1126/sageke.2004.1.pe2DOI Listing
January 2004

In situ gene expression analysis during BMP2-induced ectopic bone formation in mice shows simultaneous endochondral and intramembranous ossification.

Growth Factors 2002 Dec;20(4):197-210

GSF Research Center Institute of Mammalian Genetics, Ingolstädter Landrtr. 1, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1080/0897719021000069579DOI Listing
December 2002

Mice, microbes and models of infection.

Nat Rev Genet 2003 Mar;4(3):195-205

German Research Centre for Biotechnology (GBF), Mascheroder Weg 1, D-38124 Braunschweig, Germany

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http://www.nature.com/articles/nrg1019
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http://dx.doi.org/10.1038/nrg1019DOI Listing
March 2003

Impaired insulin secretory capacity in mice lacking a functional vitamin D receptor.

FASEB J 2003 Mar 22;17(3):509-11. Epub 2003 Jan 22.

Institute of Animal Physiology, Ludwig Maximilians University, 80539 Munich, Germany.

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http://dx.doi.org/10.1096/fj.02-0424fjeDOI Listing
March 2003

Pax1 and Pax9 activate Bapx1 to induce chondrogenic differentiation in the sclerotome.

Development 2003 Feb;130(3):473-82

GSF-National Research Center for Environment and Health, Institute of Developmental Genetics, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.

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http://dev.biologists.org/content/develop/130/3/473.full.pdf
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http://dx.doi.org/10.1242/dev.00240DOI Listing
February 2003

V76D mutation in a conserved gD-crystallin region leads to dominant cataracts in mice.

Mamm Genome 2002 Aug;13(8):452-5

GSF - National Research Center for Environment and Health, Institute of Mammalian Genetics, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1007/s00335-002-3021-6DOI Listing
August 2002

Progressive loss of PAX9 expression correlates with increasing malignancy of dysplastic and cancerous epithelium of the human oesophagus.

J Pathol 2002 Jul;197(3):293-7

Institute of Experimental Genetics, GSF-National Research Centre for Environment and Health, Neuherberg, Germany.

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http://dx.doi.org/10.1002/path.1115DOI Listing
July 2002

Genetic and molecular control of folate-homocysteine metabolism in mutant mice.

Mamm Genome 2002 May;13(5):259-67

Department of Genetics, Case Western Reserve University School of Medicine, University Hospitals of Cleveland, 10900 Euclid Avenue, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1007/s00335-001-3054-2DOI Listing
May 2002

Thymopoiesis requires Pax9 function in thymic epithelial cells.

Eur J Immunol 2002 04;32(4):1175-81

Max-Planck-Institut für Immunbiologie, Freiburg, Germany.

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http://dx.doi.org/10.1002/1521-4141(200204)32:4<1175::AID-IMMU1175>3.0.CO;2-UDOI Listing
April 2002

Conditional inactivation of Sox9: a mouse model for campomelic dysplasia.

Genesis 2002 Feb;32(2):121-3

Institute of Human Genetics, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1002/gene.10050DOI Listing
February 2002

Beethoven, a mouse model for dominant, progressive hearing loss DFNA36.

Nat Genet 2002 Mar 19;30(3):257-8. Epub 2002 Feb 19.

Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.1038/ng848DOI Listing
March 2002