Publications by authors named "Rubin M Tuder"

100Publications

Endothelial HIF-2α as a Key Endogenous Mediator Preventing Emphysema.

Am J Respir Crit Care Med 2020 Jun 9. Epub 2020 Jun 9.

VA Palo Alto, Stanford University, Medicine, Palo Alto, California, United States;

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http://dx.doi.org/10.1164/rccm.202001-0078OCDOI Listing
June 2020

Localization of Macrophages in the Human Lung via Design-based Stereology.

Am J Respir Crit Care Med 2020 05;201(10):1209-1217

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, and.

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http://dx.doi.org/10.1164/rccm.201911-2105OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233346PMC
May 2020

Perspective: pathobiological paradigms in pulmonary hypertension, time for reappraisal.

Am J Physiol Lung Cell Mol Physiol 2020 Jun 18;318(6):L1131-L1137. Epub 2020 Mar 18.

Cardiovascular Pulmonary Research Laboratories, Division of Critical Care Medicine, Departments of Pediatrics and Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado.

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http://dx.doi.org/10.1152/ajplung.00067.2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347272PMC
June 2020

Interstitial Macrophage-Derived Thrombospondin-1 Contributes to Hypoxia-Induced Pulmonary Hypertension.

Cardiovasc Res 2019 Nov 9. Epub 2019 Nov 9.

Division of Pulmonary and Critical Care Medicine, Zuckerberg San Francisco General Hospital and Trauma Center, University of California San Francisco, USA, Building 100, 3rd floor, 1001 Potrero Ave, San Francisco, CA.

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http://dx.doi.org/10.1093/cvr/cvz304DOI Listing
November 2019

GDF15 is an epithelial-derived biomarker of idiopathic pulmonary fibrosis.

Am J Physiol Lung Cell Mol Physiol 2019 10 21;317(4):L510-L521. Epub 2019 Aug 21.

Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1152/ajplung.00062.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842909PMC
October 2019

Pulmonary Arteries and Microcirculation in COPD With Pulmonary Hypertension: Bystander or Culprit?

Chest 2019 07;156(1):4-6

Department of Pathology, University of Colorado School of Medicine, Aurora, CO. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2019.04.100DOI Listing
July 2019

Bringing Light to Chronic Obstructive Pulmonary Disease Pathogenesis and Resilience.

Authors:
Rubin M Tuder

Ann Am Thorac Soc 2018 12;15(Suppl 4):S227-S233

Program in Translational Lung Research and Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado.

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http://dx.doi.org/10.1513/AnnalsATS.201808-583MGDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944393PMC
December 2018

A Review of Neuropathological Features of Familial and Adult Hemophagocytic Lymphohistiocytosis.

J Neuropathol Exp Neurol 2019 03;78(3):197-208

Department of Pathology, University of Colorado School of Medicine, Aurora, Colorado.

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https://academic.oup.com/jnen/advance-article/doi/10.1093/jn
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http://dx.doi.org/10.1093/jnen/nlz001DOI Listing
March 2019

Systems Analysis of the Human Pulmonary Arterial Hypertension Lung Transcriptome.

Am J Respir Cell Mol Biol 2019 06;60(6):637-649

1 Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.

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https://www.atsjournals.org/doi/10.1165/rcmb.2018-0368OC
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http://dx.doi.org/10.1165/rcmb.2018-0368OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543748PMC
June 2019

Paclitaxel blocks Th2-mediated TGF-β activation in Schistosoma mansoni-induced pulmonary hypertension.

Pulm Circ 2019 Jan-Mar;9(1):2045894018820813. Epub 2018 Dec 4.

Program in Translational Lung Research, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

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http://dx.doi.org/10.1177/2045894018820813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304706PMC
December 2018

Cardiopulmonary remodeling in fattened beef cattle: a naturally occurring large animal model of obesity-associated pulmonary hypertension with left heart disease.

Pulm Circ 2019 Jan-Mar;9(1):2045894018796804. Epub 2018 Aug 20.

1 Department of Pediatrics, Critical Care Medicine and Cardiovascular Pulmonary Research Labs, University of Colorado Denver Anschutz School of Medicine, Aurora, CO, USA.

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http://dx.doi.org/10.1177/2045894018796804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333945PMC
August 2018

Lung Histological Methods.

Methods Mol Biol 2018 ;1809:315-329

Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.

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http://dx.doi.org/10.1007/978-1-4939-8570-8_20DOI Listing
March 2019

Peroxisome Proliferator-activated Receptor γ and Mitochondria: Drivers or Passengers on the Road to Pulmonary Hypertension?

Am J Respir Cell Mol Biol 2018 05;58(5):555-557

2 Department of Medicine University of Colorado Anschutz Medical Campus Aurora, Colorado.

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http://dx.doi.org/10.1165/rcmb.2017-0318EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946332PMC
May 2018

Advanced Microengineered Lung Models for Translational Drug Discovery.

SLAS Discov 2018 09 15;23(8):777-789. Epub 2018 Feb 15.

1 Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.

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http://dx.doi.org/10.1177/2472555218760217DOI Listing
September 2018

Dynamic and diverse changes in the functional properties of vascular smooth muscle cells in pulmonary hypertension.

Cardiovasc Res 2018 03;114(4):551-564

Pulmonary and Critical Care Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, 12700 E. 19th Avenue, RC2, B131, Aurora, CO 80045, USA.

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https://academic.oup.com/cardiovascres/article/114/4/551/482
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http://dx.doi.org/10.1093/cvr/cvy004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852549PMC
March 2018

Hypoxia-Inducible Factor 1α Signaling Promotes Repair of the Alveolar Epithelium after Acute Lung Injury.

Am J Pathol 2017 Aug 12;187(8):1772-1786. Epub 2017 Jun 12.

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, National Jewish Health, Denver, Colorado; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver, Aurora, Colorado. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530913PMC
August 2017

Pulmonary vascular remodeling in pulmonary hypertension.

Authors:
Rubin M Tuder

Cell Tissue Res 2017 03 26;367(3):643-649. Epub 2016 Dec 26.

Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus Research 2, Room 9001, 12700 East 19th Avenue, Aurora, CO 80045, USA.

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http://link.springer.com/10.1007/s00441-016-2539-y
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http://dx.doi.org/10.1007/s00441-016-2539-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408737PMC
March 2017

Fatty Acid Metabolism, Bone Morphogenetic Protein Receptor Type 2, and the Right Ventricle.

Am J Respir Crit Care Med 2016 09;194(6):655-6

1 Department of Medicine University of Colorado Anschutz Medical Campus Aurora, Colorado.

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http://dx.doi.org/10.1164/rccm.201603-0592EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027232PMC
September 2016

Changes in Aortic Wall Structure, Composition, and Stiffness With Continuous-Flow Left Ventricular Assist Devices: A Pilot Study.

Circ Heart Fail 2015 Sep 1;8(5):944-52. Epub 2015 Jul 1.

From the Department of Medicine, Division of Cardiology (A.V.A.), Department of Bioengineering (K.S.H., R.B.D.), Department of Pediatrics, Division of Cardiology (K.S.H.), Department of Surgery, Division of Cardiothoracic Surgery (A.N.B.), Department of Medicine, Divisions of Pulmonary Sciences and Critical Care Medicine (R.M.T.), and Department of Surgery, Division of Pediatric Surgery (R.B.D.), University of Colorado, Aurora; and Vanderbilt Heart and Vascular Institute, Nashville, TN (J.L.).

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https://www.ahajournals.org/doi/10.1161/CIRCHEARTFAILURE.114
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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.114.001955DOI Listing
September 2015

Severe pulmonary hypertension is associated with altered right ventricle metabolic substrate uptake.

Am J Physiol Lung Cell Mol Physiol 2015 Sep 26;309(5):L435-40. Epub 2015 Jun 26.

Department of Medicine, University of Colorado Denver, Aurora, Colorado;

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http://dx.doi.org/10.1152/ajplung.00169.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556932PMC
September 2015

Telomere dysfunction causes alveolar stem cell failure.

Proc Natl Acad Sci U S A 2015 Apr 3;112(16):5099-104. Epub 2015 Apr 3.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, and McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205;

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http://dx.doi.org/10.1073/pnas.1504780112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413294PMC
April 2015

Novosphingobium and its potential role in chronic obstructive pulmonary diseases: insights from microbiome studies.

PLoS One 2014 23;9(10):e111150. Epub 2014 Oct 23.

University of Colorado - School of Medicine, Department of Pediatrics, Pulmonary Medicine, Mucosal and Vaccine Research Colorado, Microbiome Research Colorado, Children's Hospital Colorado, Aurora, Colorado, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111150PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207766PMC
January 2016

Rtp801 suppression of epithelial mTORC1 augments endotoxin-induced lung inflammation.

Am J Pathol 2014 Sep 9;184(9):2382-9. Epub 2014 Jul 9.

Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2014.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188171PMC
September 2014

Role of vascular endothelial growth factor signaling in Schistosoma-induced experimental pulmonary hypertension.

Pulm Circ 2014 Jun;4(2):289-99

Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, Anschutz Medical Campus, University of Colorado Denver, Aurora, Colorado, USA ; Pulmonary Vascular Research Institute.

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http://journals.sagepub.com/doi/10.1086/675992
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http://dx.doi.org/10.1086/675992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070790PMC
June 2014

The crossroads of iron with hypoxia and cellular metabolism. Implications in the pathobiology of pulmonary hypertension.

Am J Respir Cell Mol Biol 2014 Dec;51(6):721-9

1 Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado; and.

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http://dx.doi.org/10.1165/rcmb.2014-0021TRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291546PMC
December 2014

Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension.

J Immunol 2014 Jul 13;193(2):597-609. Epub 2014 Jun 13.

Division of Critical Care Medicine/Cardiovascular Pulmonary Research Laboratories, Department of Pediatrics and Medicine, School of Medicine, University of Colorado Denver, Aurora, CO 80045;

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http://dx.doi.org/10.4049/jimmunol.1303048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100597PMC
July 2014

How do we measure pathology in PAH (lung and RV) and what does it tell us about the disease.

Authors:
Rubin M Tuder

Drug Discov Today 2014 Aug 29;19(8):1257-63. Epub 2014 May 29.

Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, 12700 East 18th Avenue, Research Complex 2, Room 9001, Aurora, CO 80045, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2014.05.022DOI Listing
August 2014

Altered nutrient response of mTORC1 as a result of changes in REDD1 expression: effect of obesity vs. REDD1 deficiency.

J Appl Physiol (1985) 2014 Aug 29;117(3):246-56. Epub 2014 May 29.

Department of Exercise and Nutrition Sciences, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York;

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http://www.physiology.org/doi/10.1152/japplphysiol.01350.201
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http://dx.doi.org/10.1152/japplphysiol.01350.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122690PMC
August 2014

Progress in solving the sex hormone paradox in pulmonary hypertension.

Am J Physiol Lung Cell Mol Physiol 2014 Jul 9;307(1):L7-26. Epub 2014 May 9.

Division of Pulmonary, Allergy, Critical Care, Occupational and Sleep Medicine, and Richard L. Roudebush VA Medical Center; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana; and.

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http://ajplung.physiology.org/content/ajplung/307/1/L7.full.
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http://ajplung.physiology.org/lookup/doi/10.1152/ajplung.003
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http://dx.doi.org/10.1152/ajplung.00337.2013DOI Listing
July 2014

Fat and cardiotoxicity in hereditary pulmonary hypertension.

Am J Respir Crit Care Med 2014 Feb;189(3):247-9

1 Division of Pulmonary Sciences and Critical Care Medicine University of Colorado School of Medicine Aurora, Colorado.

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http://dx.doi.org/10.1164/rccm.201312-2240EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977738PMC
February 2014

Heparanase mediates renal dysfunction during early sepsis in mice.

Physiol Rep 2013 Nov 11;1(6):e00153. Epub 2013 Nov 11.

Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine Aurora, Colorado ; Denver Health Medical Center Denver, Colorado.

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http://dx.doi.org/10.1002/phy2.153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871468PMC
November 2013

Relevant issues in the pathology and pathobiology of pulmonary hypertension.

J Am Coll Cardiol 2013 Dec;62(25 Suppl):D4-12

Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2013.10.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970402PMC
December 2013

Mammalian target of rapamycin complex 2 (mTORC2) coordinates pulmonary artery smooth muscle cell metabolism, proliferation, and survival in pulmonary arterial hypertension.

Circulation 2014 Feb 22;129(8):864-74. Epub 2013 Nov 22.

Pulmonary, Allergy & Critical Care Division (D.A.G., T.V.K., H.Z., H.D., V.P.K., S.M.K., E.A.G.), Department of Pathology and Laboratory Medicine (K.I.-S.), Pulmonary Vascular Disease Program (K.I.-S., H.D., V.P.K., S.M.K., E.A.G.), Center for Clinical Epidemiology and Biostatistics (S.M.K.), and Abramson Cancer Center (V.P.K.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver, Aurora, CO (R.M.T.); and Division of Pulmonary, Allergy and Critical Care Medicine, Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA (D.A.G., T.V.K.). Dr Goncharova's current affiliation is the Division of Pulmonary, Allergy and Critical Care Medicine, Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.004581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968690PMC
February 2014

Pathology of pulmonary hypertension.

Clin Chest Med 2013 Dec 17;34(4):639-50. Epub 2013 Oct 17.

Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, 12700 East 19th Avenue, Research Complex 2, Room 9001, Aurora, CO 80045, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccm.2013.08.009DOI Listing
December 2013

Pulmonary veins in the normal lung and pulmonary hypertension due to left heart disease.

Am J Physiol Lung Cell Mol Physiol 2013 Nov 13;305(10):L725-36. Epub 2013 Sep 13.

Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Univ. of Colorado Denver, Anschutz Medical Campus, Research 2 - 9th floor, Rm. 9001; Mail stop C-272, 12700 East 19th Ave., Aurora, CO 80045.

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http://www.physiology.org/doi/10.1152/ajplung.00186.2013
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http://dx.doi.org/10.1152/ajplung.00186.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840271PMC
November 2013

Transforming growth factor-β signaling promotes pulmonary hypertension caused by Schistosoma mansoni.

Circulation 2013 Sep 19;128(12):1354-64. Epub 2013 Aug 19.

Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine (B.B.G., J.C., L.G., J.P., E.D., L.D., T.T., L.S., N.D., R.W.V.) and Department of Pathology (X.-J.W.), Anschutz Medical Campus, Aurora, CO; Pulmonary Vascular Research Institute (B.B.G., A.B., H.C.C., G.B., R.M.T.); Memorial S. Jose Hospital, Universidade de Pernambuco in Recife, Recife, Brazil (A.B.); Division of Cardiology, University of Pittsburgh, Pittsburgh, PA (H.C.C.); School of Pharmacy, University of Kent, Kent, UK (G.B.); and Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD (T.A.W.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.003072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880024PMC
September 2013

α₁-Antitrypsin modulates lung endothelial cell inflammatory responses to TNF-α.

Am J Respir Cell Mol Biol 2013 Jul;49(1):143-50

Division of Pulmonary, Allergy, Critical Care, and Occupational Medicine, Center for Immunobiology, Indiana University, Indianapolis, IN 46202, USA.

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http://dx.doi.org/10.1165/rcmb.2012-0515OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727880PMC
July 2013

Pathogenesis of chronic obstructive pulmonary disease.

J Clin Invest 2012 Aug 1;122(8):2749-55. Epub 2012 Aug 1.

Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado, School of Medicine, Denver, CO, USA.

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http://dx.doi.org/10.1172/JCI60324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408733PMC
August 2012

The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis.

Nat Med 2012 Aug 22;18(8):1217-23. Epub 2012 Jul 22.

Department of Medicine, Division of Pulmonary Sciences and Critical Care Medicine, Program in Translational Lung Research, University of Colorado School of Medicine, Aurora, Colorado, USA; Denver Health Medical Center, Denver, Colorado, USA.

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https://pdfs.semanticscholar.org/fb2b/bbf1876c32d7d47b5b5d51
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http://www.nature.com/articles/nm.2843
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http://dx.doi.org/10.1038/nm.2843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723751PMC
August 2012

Senescence in chronic obstructive pulmonary disease.

Proc Am Thorac Soc 2012 May;9(2):62-3

Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA.

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http://dx.doi.org/10.1513/pats.201201-012MSDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359109PMC
May 2012

Significant intrapulmonary Schistosoma egg antigens are not present in schistosomiasis-associated pulmonary hypertension.

Pulm Circ 2011 Oct-Dec;1(4):456-61

Department of Medicine, Program in Translational Lung Research, University of Colorado Denver, Denver, CO, USA.

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http://dx.doi.org/10.4103/2045-8932.93544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329075PMC
August 2012

Targeting energetic metabolism: a new frontier in the pathogenesis and treatment of pulmonary hypertension.

Am J Respir Crit Care Med 2012 Feb 10;185(3):260-6. Epub 2011 Nov 10.

Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, USA.

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http://dx.doi.org/10.1164/rccm.201108-1536PPDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297113PMC
February 2012

Stress responses affecting homeostasis of the alveolar capillary unit.

Proc Am Thorac Soc 2011 Nov;8(6):485-91

Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA.

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http://dx.doi.org/10.1513/pats.201103-029MWDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359075PMC
November 2011

Chair's summary: pulmonary circulation in health and disease.

Authors:
Rubin M Tuder

Proc Am Thorac Soc 2011 Nov;8(6):452

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http://dx.doi.org/10.1513/pats.201108-051MWDOI Listing
November 2011

Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease.

J Clin Invest 2011 Nov 17;121(11):4548-66. Epub 2011 Oct 17.

Department of Pharmacology and Toxicology, Medical College of Georgia, Georgia Health Sciences University, Augusta, Georgia, USA.

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http://dx.doi.org/10.1172/JCI57734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204840PMC
November 2011

Telomere length is a determinant of emphysema susceptibility.

Am J Respir Crit Care Med 2011 Oct 14;184(8):904-12. Epub 2011 Jul 14.

Department of Oncology, Johns Hopkins University School of Medicine, 1650 Orleans Street, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1164/rccm.201103-0520OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208661PMC
October 2011

Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences.

Int J Chron Obstruct Pulmon Dis 2011 13;6:209-17. Epub 2011 Mar 13.

Department of Pharmacology and Center for Lung Biology, University of South Alabama College of Medicine, Mobile, AL 36688, USA.

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http://dx.doi.org/10.2147/COPD.S15922DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107697PMC
October 2011

Just in the "Bik" of time.

Am J Respir Crit Care Med 2011 Jun;183(11):1447-8

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http://dx.doi.org/10.1164/rccm.201103-0566EDDOI Listing
June 2011

Partial netrin-1 deficiency aggravates acute kidney injury.

PLoS One 2011 19;6(5):e14812. Epub 2011 May 19.

Mucosal Inflammation Program, Department of Anesthesiology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0014812PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098227PMC
November 2011

Dependence of Golgi apparatus integrity on nitric oxide in vascular cells: implications in pulmonary arterial hypertension.

Am J Physiol Heart Circ Physiol 2011 Apr 7;300(4):H1141-58. Epub 2011 Jan 7.

Department of Cell Biology and Anatomy, New York Medical College, Valhalla, 10595, USA.

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http://dx.doi.org/10.1152/ajpheart.00767.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075042PMC
April 2011

Lung disease associated with alpha1-antitrypsin deficiency.

Proc Am Thorac Soc 2010 Nov;7(6):381-6

Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado at Denver, Aurora, Colorado, USA.

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http://dx.doi.org/10.1513/pats.201002-020AWDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136958PMC
November 2010

Increased expression of growth differentiation factor-15 in systemic sclerosis-associated pulmonary arterial hypertension.

Chest 2011 May 9;139(5):994-1002. Epub 2010 Sep 9.

Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver, Denver, CO. Electronic address:

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http://dx.doi.org/10.1378/chest.10-0302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087455PMC
May 2011