Ruben Tommasi

Ruben Tommasi

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Ruben Tommasi

Ruben Tommasi

Publications by authors named "Ruben Tommasi"

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24Publications

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Role of the Klebsiella pneumoniae TolC porin in antibiotic efflux.

Res Microbiol 2019 Mar 20;170(2):112-116. Epub 2018 Nov 20.

Entasis Therapeutics, 35 Gatehouse Drive, Waltham, MA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09232508183014
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http://dx.doi.org/10.1016/j.resmic.2018.11.003DOI Listing
March 2019

Titrating Levels of TolC in E. coli: A Sensitive Approach to Quantifying Efflux.

ACS Infect Dis 2019 01 30;5(1):49-54. Epub 2018 Nov 30.

Entasis Therapeutics Inc. , 35 Gatehouse Drive , Waltham , Massachusetts 02451 , United States.

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http://dx.doi.org/10.1021/acsinfecdis.8b00273DOI Listing
January 2019

Antibacterial Drug Discovery: Some Assembly Required.

ACS Infect Dis 2018 05 29;4(5):686-695. Epub 2018 Mar 29.

Entasis Therapeutics, Inc. , 35 Gatehouse Drive , Waltham , Massachusetts 02451 , United States.

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http://dx.doi.org/10.1021/acsinfecdis.8b00027DOI Listing
May 2018

Acinetobacter baumannii OmpA Is a Selective Antibiotic Permeant Porin.

ACS Infect Dis 2018 03 26;4(3):373-381. Epub 2017 Dec 26.

Entasis Therapeutics , 35 Gatehouse Drive , Waltham , Massachusetts 02451 , United States.

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http://dx.doi.org/10.1021/acsinfecdis.7b00168DOI Listing
March 2018

Whole-Cell-Based Assay To Evaluate Structure Permeation Relationships for Carbapenem Passage through the Pseudomonas aeruginosa Porin OprD.

ACS Infect Dis 2017 04 17;3(4):310-319. Epub 2017 Feb 17.

Entasis Therapeutics, Inc. , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States.

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http://dx.doi.org/10.1021/acsinfecdis.6b00197DOI Listing
April 2017

ESKAPEing the labyrinth of antibacterial discovery.

Nat Rev Drug Discov 2015 08 3;14(8):529-42. Epub 2015 Jul 3.

Entasis Therapeutics, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA.

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http://dx.doi.org/10.1038/nrd4572DOI Listing
August 2015

Toward the rational design of carbapenem uptake in Pseudomonas aeruginosa.

Chem Biol 2015 Apr;22(4):535-547

AstraZeneca Infection Innovative Medicines, 35 Gatehouse Drive, Waltham, MA 02451, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2015.03.018DOI Listing
April 2015

Trends and exceptions of physical properties on antibacterial activity for Gram-positive and Gram-negative pathogens.

J Med Chem 2014 Dec 2;57(23):10144-61. Epub 2014 Dec 2.

Infection Innovative Medicines, AstraZeneca Pharmaceuticals , 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States.

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http://pubs.acs.org/doi/10.1021/jm501552x
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http://dx.doi.org/10.1021/jm501552xDOI Listing
December 2014

Atomic-scale characterization of conformational changes in the preQ₁ riboswitch aptamer upon ligand binding.

J Mol Graph Model 2011 Sep 22;30:179-85. Epub 2011 Jul 22.

Novartis Institutes for BioMedical Research, Inc., 100 Technology Square & 250 Massachusetts Ave. Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.jmgm.2011.07.006DOI Listing
September 2011

Optimization of halopemide for phospholipase D2 inhibition.

Bioorg Med Chem Lett 2007 Apr 25;17(8):2310-1. Epub 2007 Jan 25.

Novartis Institutes for BioMedical Research, 100 Technology Square, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.bmcl.2007.01.059DOI Listing
April 2007