Publications by authors named "Ruben D Sinisterra"

51Publications

Polycaprolactone nanofibers loaded oxytetracycline hydrochloride and zinc oxide for treatment of periodontal disease.

Mater Sci Eng C Mater Biol Appl 2019 Oct 27;103:109798. Epub 2019 May 27.

Restorative Dentistry Department, Faculty of Dentistry, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos 6627, Belo Horizonte, MG CEP 31270901, Brazil. Electronic address:

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October 2019

Testosterone improves the osteogenic potential of a composite in vitro and in vivo.

Cell Tissue Res 2019 May 12;376(2):221-231. Epub 2019 Jan 12.

Restorative Dentistry Department, Dentistry Faculty, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, Belo Horizonte, CEP 31270901, Brazil.

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May 2019

A long-lasting oral preformulation of the angiotensin II AT1 receptor antagonist losartan.

Drug Dev Ind Pharm 2018 Sep 10;44(9):1498-1505. Epub 2018 May 10.

a Laboratório de Encapsulamento Molecular e Biomateriais (LEMB), Chemistry Department, Universidade Federal de Minas Gerais (UFMG) , Belo Horizonte , MG , Brazil.

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September 2018

Hybrid nanofibers based on poly-caprolactone/gelatin/hydroxyapatite nanoparticles-loaded Doxycycline: Effective anti-tumoral and antibacterial activity.

Mater Sci Eng C Mater Biol Appl 2018 Feb 3;83:25-34. Epub 2017 Aug 3.

Chemistry Depatment, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos 6627, Belo Horizonte, MG CEP 31270-901, Brazil. Electronic address:

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February 2018

Efficient antibacterial nanosponges based on ZnO nanoparticles and doxycycline.

J Photochem Photobiol B 2017 Dec 18;177:85-94. Epub 2017 Oct 18.

Chemistry Department, Universidade Federal de Minas Gerais, Belo Horizonte, MG CEP: 31270-901, Brazil. Electronic address:

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December 2017

Antidiarrheal activity of extracts from Maytenus gonoclada and inhibition of Dengue virus by lupeol.

An Acad Bras Cienc 2017 Jul-Sep;89(3):1555-1564

Universidade Federal de Minas Gerais, Departamento de Química, Instituto de Ciências Exatas, Avenida Antônio Carlos, 6627, 31270-901 Belo Horizonte, MG, Brazil.

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April 2018

Sub-additive effects of photodynamic therapy combined with erlotinib for the treatment of epidermoid carcinoma: An in vitro study.

Photodiagnosis Photodyn Ther 2017 Jun 23;18:252-256. Epub 2017 Mar 23.

Restorative Dentistry Department, Faculty of Dentistry, Universidade Federal de Minas Gerais, Av. Antônio Carlos 6627, CEP 31270-901 Belo Horizonte, MG, Brazil. Electronic address:

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June 2017

Magnetic nanoparticles coated with cyclodextrins and citrate for irinotecan delivery.

Carbohydr Polym 2017 May 2;163:1-9. Epub 2016 Dec 2.

Chemistry Department, Exact Sciences Institute, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos 6627, Belo Horizonte, MG 31270-901, Brazil. Electronic address:

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May 2017

KR12 peptide associated with cyclodextrin: Antimicrobial and antitumor activities.

Biointerphases 2016 12 1;11(4):04B307. Epub 2016 Dec 1.

Department of Chemistry-Exact Science Institute, Universidade Federal de Minas Gerais, Av. Antonio Carlos, 6627, CEP 31270-901 Belo Horizonte, MG, Brazil and National Institute of Science and Technology in Nano-Biopharmaceutical, Belo Horizonte, MG, 31270901, Brazil.

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December 2016

Nanofibers containing tetracycline/β-cyclodextrin: Physico-chemical characterization and antimicrobial evaluation.

Carbohydr Polym 2017 Jan 18;156:417-426. Epub 2016 Sep 18.

Restorative Dentistry Department, Faculty of Dentistry, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos 6627, Belo Horizonte, MG, CEP 31270-901, Brazil. Electronic address:

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January 2017

PLGA nanofibers improves the antitumoral effect of daunorubicin.

Colloids Surf B Biointerfaces 2015 Dec 7;136:248-55. Epub 2015 Sep 7.

Chemistry Department, Institute of Exact Sciences, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, Pampulha, CEP 31270-901 Belo Horizonte, MG, Brazil. Electronic address:

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December 2015

Electrospun nanofibers of polyCD/PMAA polymers and their potential application as drug delivery system.

Mater Sci Eng C Mater Biol Appl 2015 Sep 22;54:252-61. Epub 2015 Apr 22.

Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, 31270-901 MG, Brazil.

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September 2015

Development of a calcium phosphate nanocomposite for fast fluorogenic detection of bacteria.

Molecules 2014 Sep 5;19(9):13948-64. Epub 2014 Sep 5.

Restorative Dentistry Department, Faculty of Dentistry, Universidade Federal de Minas Gerais, Av. Antônio Carlos 6627, CEP 31270-901 Belo Horizonte, MG, Brazil.

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September 2014

Structural and thermodynamic characterization of doxycycline/β-cyclodextrin supramolecular complex and its bacterial membrane interactions.

Colloids Surf B Biointerfaces 2014 Jun 19;118:194-201. Epub 2014 Apr 19.

Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Av. Antonio Carlos 6627, Pampulha, 31270-901, Belo Horizonte, MG, Brazil. Electronic address:

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June 2014

Cross talk between angiotensin-(1-7)/Mas axis and sirtuins in adipose tissue and metabolism of high-fat feed mice.

Peptides 2014 May 15;55:158-65. Epub 2014 Mar 15.

Laboratory of Health Science, Postgraduate Program in Health Sciences, Universidade Estadual de Montes Claros, Montes Claros, Minas Gerais, Brazil; Institute of Biological Sciences, Department of Pharmacology, Universidade Federal de Minas Gerais, Minas Gerais, Brazil; Department of Physiology and Biophysics, Universidade Federal de Minas Gerais, Minas Gerais, Brazil. Electronic address:

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May 2014

Control of size in losartan/copper(II) coordination complex hydrophobic precipitate.

Mater Sci Eng C Mater Biol Appl 2013 Oct 22;33(7):3916-22. Epub 2013 May 22.

Departamento de Farmácia, Universidade Federal de Juiz de Fora (UFJF), Campus Governador Valadares, Av. Dr. Raimundo Monteiro de Rezende, 330, Centro, 35010-177 Governador Valadares, MG, Brazil.

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October 2013

Self-assembled organic-inorganic magnetic hybrid adsorbent ferrite based on cyclodextrin nanoparticles.

Beilstein J Org Chem 2012 1;8:1867-76. Epub 2012 Nov 1.

Centro Federal de Educação Tecnológica (CEFET-MG), Campus VII, Timóteo, MG, Brazil 35183-006 ; Universidade Federal de Juiz de Fora (UFJF), Governador Valadares, 35010-177, MG, Brazil.

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December 2012

Insights into the multi-equilibrium, superstructure system based on β-cyclodextrin and a highly water soluble guest.

Int J Pharm 2012 Dec 25;439(1-2):207-15. Epub 2012 Sep 25.

Núcleo de Espectroscopia e Estrutura Molecular, Departamento de Química, Universidade Federal de Juiz de Fora, Campus Universitário s/n, Martelos, Juiz de Fora, MG, 36036-900, Brazil.

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December 2012

Effect of testosterone incorporation on cell proliferation and differentiation for polymer-bioceramic composites.

J Mater Sci Mater Med 2012 Nov 11;23(11):2751-9. Epub 2012 Aug 11.

Departamento de Odontologia Restauradora, Faculdade de Odontologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

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November 2012

In vivo evaluation of the highly soluble oral β-cyclodextrin-Sertraline supramolecular complexes.

Int J Pharm 2012 Oct 6;436(1-2):478-85. Epub 2012 Jul 6.

Laboratório de Encapsulamento Molecular e Biomateriais (LEMB) - Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG 31270-901, Brazil.

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October 2012

Beneficial effects of long-term administration of an oral formulation of Angiotensin-(1-7) in infarcted rats.

Int J Hypertens 2012 9;2012:795452. Epub 2012 Feb 9.

National Institute of Science and Technology in Nanobiopharmaceutics, Federal University of Minas Gerais, 31.270-901 Belo Horizonte, MG, Brazil.

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August 2012

Superstructure based on β-CD self-assembly induced by a small guest molecule.

Phys Chem Chem Phys 2012 Feb 10;14(6):1934-44. Epub 2012 Jan 10.

Laboratório de Encapsulamento Molecular e Biomateriais (LEMB), Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, 31270-901, MG, Brazil.

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February 2012

Strategies to target tumors using nanodelivery systems based on biodegradable polymers, aspects of intellectual property, and market.

J Chem Biol 2012 30;6(1):7-23. Epub 2012 Nov 30.

Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais (UFMG), Avenida Pres. Antônio Carlos 6627, Pampulha, CEP: 31270-901 Belo Horizonte, Minas Gerais Brazil.

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December 2013

Condensation silicones: do new materials really presents better dimensional stability?

Acta Odontol Latinoam 2011 ;24(1):61-5

Department of Restorative Dentistry, School of Dentistry, Minas Gerais Federal University, Belo Horizonte, Brazil.

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January 2012

Multi-equilibrium system based on sertraline and β-cyclodextrin supramolecular complex in aqueous solution.

Int J Pharm 2011 Dec 22;421(1):24-33. Epub 2011 Sep 22.

Laboratório de Encapsulamento Molecular e Biomateriais - Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, MG, Brazil.

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December 2011

An orally active formulation of angiotensin-(1-7) produces an antithrombotic effect.

Clinics (Sao Paulo) 2011 ;66(5):837-41

Instituto Nacional de Ciência e Tecnologia em Nanobiofarmacêutica - Department of Physiology and Biophysics, Biological Science Institute, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

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June 2012

Inhibition of Candida albicans CC biofilms formation in polystyrene plate surfaces by biosurfactant produced by Trichosporon montevideense CLOA72.

Colloids Surf B Biointerfaces 2011 Jun 3;84(2):467-76. Epub 2011 Mar 3.

Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, C.P. 486, 31270-901, Belo Horizonte, MG, Brazil.

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June 2011

An oral formulation of angiotensin-(1-7) produces cardioprotective effects in infarcted and isoproterenol-treated rats.

Hypertension 2011 Mar 31;57(3):477-83. Epub 2011 Jan 31.

Department of Physiology and Biophysics, National Institute of Science and Technology in Nanobiopharmaceutics, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

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March 2011

Photo-response behavior of electrospun nanofibers based on spiropyran-cyclodextrin modified polymer.

J Mater Chem 2010 Nov 28;20(44):9910-9917. Epub 2010 Sep 28.

Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.

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November 2010

Supramolecular interactions between losartan and hydroxypropyl-β-CD: ESI mass-spectrometry, NMR techniques, phase solubility, isothermal titration calorimetry and anti-hypertensive studies.

Int J Pharm 2011 Feb 17;404(1-2):116-23. Epub 2010 Nov 17.

Laboratório de Encapsulamento Molecular e Biomateriais, Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Av Antônio Carlos 6627, Belo Horizonte 31270-901, MG, Brazil.

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February 2011

Quercetin/beta-cyclodextrin solid complexes prepared in aqueous solution followed by spray-drying or by physical mixture.

AAPS PharmSciTech 2009 12;10(1):235-42. Epub 2009 Mar 12.

Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

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June 2009

Studies on coumestrol/beta-cyclodextrin association: Inclusion complex characterization.

Int J Pharm 2009 Mar 5;369(1-2):5-11. Epub 2008 Nov 5.

Programa de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul. Av. Ipiranga, 2752, Porto Alegre 90.610-000, RS, Brazil.

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March 2009

Complexation with beta-cyclodextrin confers oral activity on the flavonoid dioclein.

Int J Pharm 2009 Feb 7;367(1-2):133-9. Epub 2008 Oct 7.

Departamento de Fisiologia e Biofísica, ICB, Universidade Federal de Minas Gerais, Av Antônio Carlos 6627, 31270-901 Belo Horizonte, MG, Brazil.

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February 2009

Supramolecular self-assembly of cyclodextrin and higher water soluble guest: thermodynamics and topological studies.

J Am Chem Soc 2008 Jul 5;130(26):8426-36. Epub 2008 Jun 5.

Laboratório de Encapsulamento Molecular e Biomateriais-Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil 31270-901.

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July 2008

Supramolecular complex of fluoxetine with beta-cyclodextrin: an experimental and theoretical study.

Int J Pharm 2008 Apr 3;353(1-2):160-9. Epub 2007 Dec 3.

Laboratório de Encapsulamento Molecular e Biomateriais (LEMB), Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.

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April 2008

Study of angiotensin-(1-7) vasoactive peptide and its beta-cyclodextrin inclusion complexes: complete sequence-specific NMR assignments and structural studies.

Peptides 2007 Nov 19;28(11):2199-210. Epub 2007 Aug 19.

Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Av. Antonio Carlos 6627, 31270-901 Belo Horizonte, Minas Gerais, Brazil.

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November 2007

Supramolecular self-assembly of beta-cyclodextrin: an effective carrier of the antimicrobial agent chlorhexidine.

Carbohydr Res 2007 Nov 16;342(15):2286-96. Epub 2007 May 16.

Departamento de Química, Instituto de Ciências Exactas, Universidade Federal de Minas Gerais, UFMG, Avenida Antônio Carlos 6627, 31270-901, Belo Horizonte, MG, Brazil.

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November 2007

Polymer: bioceramic composites optimization by tetracycline addition.

Int J Pharm 2007 May 25;336(1):75-81. Epub 2006 Nov 25.

Departamento de Odontologia Restauradora da Faculdade de Odontologia da Universidade Federal de Minas Gerais (UFMG), Brazil.

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May 2007

Mode of action of beta-cyclodextrin as an absorption enhancer of the water-soluble drug meglumine antimoniate.

Int J Pharm 2006 Nov 13;325(1-2):39-47. Epub 2006 Jun 13.

Departamento de Fisiologia e Biofísica, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Antônio Carlos 6627, Pampulha, 31270-901 Belo Horizonte, MG, Brazil.

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November 2006

An alternative approach based on artificial neural networks to study controlled drug release.

J Pharm Sci 2004 Feb;93(2):418-30

Departamento de Química-ICEx, Universidade Federal de Minas Gerais, Pampulha, (31.270-901) Belo Horizonte, MG-Brazil.

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February 2004

Oral delivery of meglumine antimoniate-beta-cyclodextrin complex for treatment of leishmaniasis.

Antimicrob Agents Chemother 2004 Jan;48(1):100-3

Departamento de Química, ICEX, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil.

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January 2004