Publications by authors named "Ruben Cloete"

16Publications

Structural Comparison of Diverse HIV-1 Subtypes using Molecular Modelling and Docking Analyses of Integrase Inhibitors.

Viruses 2020 08 26;12(9). Epub 2020 Aug 26.

Division of Medical Virology, Department of Pathology, Faculty of Medicine and Health Sciences, Stellenbosch University, Francie van Zijl Avenue, P.O. Box 241, Cape Town 8000, South Africa.

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http://dx.doi.org/10.3390/v12090936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552036PMC
August 2020

HIV-1 Drug Resistance Mutation Analyses of Cameroon-Derived Integrase Sequences.

AIDS Res Hum Retroviruses 2020 Aug 10. Epub 2020 Aug 10.

Division of Medical Virology, Department of Pathology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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http://dx.doi.org/10.1089/AID.2020.0022DOI Listing
August 2020

Molecular dynamic simulations to investigate the structural impact of known drug resistance mutations on HIV-1C Integrase-Dolutegravir binding.

PLoS One 2020 7;15(5):e0223464. Epub 2020 May 7.

South African Medical Research Council Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape, Cape Town, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0223464PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205217PMC
August 2020

Drug Resistance Mutations Against Protease, Reverse Transcriptase and Integrase Inhibitors in People Living With HIV-1 Receiving Boosted Protease Inhibitors in South Africa.

Front Microbiol 2020 20;11:438. Epub 2020 Mar 20.

Division of Medical Virology, Department of Pathology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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http://dx.doi.org/10.3389/fmicb.2020.00438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099763PMC
March 2020

HIV-1 Integrase Diversity and Resistance-Associated Mutations and Polymorphisms Among Integrase Strand Transfer Inhibitor-Naive HIV-1 Patients from Cameroon.

AIDS Res Hum Retroviruses 2020 05 13;36(5):450-455. Epub 2020 Jan 13.

Division of Medical Virology, Department of Pathology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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http://dx.doi.org/10.1089/AID.2019.0264DOI Listing
May 2020

Structure based identification of novel inhibitors against ATP synthase of Mycobacterium tuberculosis: A combined in silico and in vitro study.

Int J Biol Macromol 2019 Aug 20;135:582-590. Epub 2019 May 20.

South African National Bioinformatics Institute (SANBI), SA Medical Research Council Bioinformatics Unit, University of the Western Cape, Private Bag X17, Bellville, 7535 Cape Town, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.ijbiomac.2019.05.108DOI Listing
August 2019

Author Correction: Analyses of HIV-1 integrase sequences prior to South African national HIV-treatment program and availability of integrase inhibitors in Cape Town, South Africa.

Sci Rep 2018 Apr 16;8(1):6262. Epub 2018 Apr 16.

Division of Medical Virology, Department of Pathology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, 7505, Cape Town, South Africa.

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http://dx.doi.org/10.1038/s41598-018-24183-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902626PMC
April 2018

Analyses of HIV-1 integrase sequences prior to South African national HIV-treatment program and available of integrase inhibitors in Cape Town, South Africa.

Sci Rep 2018 03 16;8(1):4709. Epub 2018 Mar 16.

Division of Medical Virology, Department of Pathology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, 7505, Cape Town, South Africa.

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http://dx.doi.org/10.1038/s41598-018-22914-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856838PMC
March 2018

Structural and functional effects of nucleotide variation on the human TB drug metabolizing enzyme arylamine N-acetyltransferase 1.

J Mol Graph Model 2017 08 10;75:330-339. Epub 2017 Jun 10.

South African Medical Research Council Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape, Private Bag X17, Bellville, Cape Town 7535, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.jmgm.2017.04.026DOI Listing
August 2017

Resistance related metabolic pathways for drug target identification in Mycobacterium tuberculosis.

BMC Bioinformatics 2016 Feb 8;17:75. Epub 2016 Feb 8.

South African Medical Research Council Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape, Bellville, South Africa.

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http://dx.doi.org/10.1186/s12859-016-0898-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745158PMC
February 2016

Comparative analysis of Mycobacterium tuberculosis pe and ppe genes reveals high sequence variation and an apparent absence of selective constraints.

PLoS One 2012 4;7(4):e30593. Epub 2012 Apr 4.

Department of Science and Technology, Medical Research Council Centre for Molecular and Cellular Biology, Stellenbosch University, Tygerberg, Cape Town, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030593PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319526PMC
August 2012